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| 1 | Tensor-Based Low-Complexity Channel Estimation for mmWave Massive MIMO-OTFS Systems显示文摘Orthogonal time frequency space(OTFS)modulation,collaborated with millimeter-wave(mmWave)massive multiple-input-multiple-output(MIMO),is a promising technology for next generation wireless communications in high mobility scenarios.However,one of the main challenges for mmWave massive MIMO-OTFS systems is the enormous computational complexity of channel estimation incurred by the huge OTFS symbol size and the large number of antennas.To address this issue,in this paper,a tensor-based orthogonal matching pursuit(OMP)channel estimation algorithm is proposed by exploiting the channel sparsity in the delay-Doppler-angle domain.In particular,we firstly propose a novel pilot design for the OTFS symbol structure in the frequency-time domain.Then,based on the proposed pilot structure,we formulate the channel estimation as a sparse signal recovery problem,and the tensor decomposition and parallel support detection are introduced into the tensor-based OMP algorithm to reduce the signal processing dimension significantly.Numerical simulations are performed to verify the superiority and the robustness of the proposed tensor-based OMP algorithm. | Xianda Wu Shaodan Ma Xi Yang | 2020 | Journal of Communications and Information Networks2020，5，3： | 5 |
| 2 | Microvascular pathological features and changes in related injury factors in a rat acute blood stasis model显示文摘OBJECTIVE: To examine the microvascular pathological characteristics and changes in related injury factors in a rat model of acute blood stasis.METHODS: A total of 75 Sprague-Dawley rats were divided randomly and equally into a control group and four experimental groups assessed at different times after the induction of stasis(0, 1, 3 or 6 h after stasis)(n = 15). The acute blood stasis model was established through rat tail-vein injection of high-molecular-weight dextran. After Electrocardiograph(ECG) detection at predetermined times(0,1, 3 and 6 h after induction of stasis), the rats were sacrificed and blood and cardiac samples were harvested for analysis. Hematoxylin-eosin(HE) staining and transmission electron microscopy were used for histopathological detection; an enzyme linked immunosorbent assay(ELISA) was used to detect thromboxane B2(TXB2) and 6-keto-prostaglandin F1α(6-Keto-PGF1α) concentrations; a real-time polymerase chain reaction(PCR) reaction system was used to detect intercellular adhesion molecule1(ICAM-1) and vascular cell adhesion molecule1(VCAM-1) m RNA expression; western blotting was used to detect vascular endothelial cadherin(VE-cadherin) protein expression.RESULTS: The ST segment in the ECG showed gradual elevation after induction of stasis and continued elevation at a high level at 3 and 6 h. The HE staining showed changes in myocardial cell necrosis and tissue dissociation after the induction of stasis, along with inflammatory infiltration. Results of transmission electron microscopy showed immediate changes in blood stasis and lumen occlusion in the microvasculature, along with endothelial cell swelling. After the induction of stasis, TXB2 concentrations gradually increased while 6-Keto-PGF1αconcentrations were immediately significantly reduced. The TXB2/6-Keto-PGF1αratio was maintained at a high level. ICAM-1 m RNA expression showed an unstable elevation while VCAM-1 m RNA expression was significantly reduced after the induction of stasis. Compared with the control group, VE-cadherin protein expression increased at 0 and 3 h after the induction of stasis, while no change occurred at 1 and 6 h.CONCLUSION: The pathological manifestations of acute blood stasis are microvascular blood retention, lumen stenosis and even occlusion. The condition is also called 'blood coagulation and weep' in Traditional Chinese Medicine. The blood stasis model resulted in the injury and necrosis of endothelial cells and cardiomyocytes, along with the presence of an imbalance of vasomotor factor levels, platelet activation, and increases in the expression of adhesion molecules and endothelial barrier dysfunction,which corresponds to 'blood failed to nourish' in Traditional Chinese Medicine. | Zhang Junxiu Feng Yu Li Shaodan, Liu Yi Zhang Yin Guo Yunxia Yang Minghui | 2017 | Journal of Traditional Chinese Medicine2017，37，1： | 5 |
| 3 | Changes in nitric oxide,angiotensinⅡ,angiopoietin-like protein 4 mRNA,neuregulin 1 mRNA,and platelet endothelial cell adhesion molecule-1 in rats with acute blood stasis induced by high-molecular-weight dextran显示文摘OBJECTIVE: To investigate the influence of acute blood stasis on nitric oxide(NO), angiotensin Ⅱ(Ang Ⅱ), angiopoietin-like protein 4(ANGPTL4)m RNA, neuregulin 1(NRG-1) m RNA, and platelet endothelial cell adhesion molecule-1(PECAM-1) in rats with stasis induced by high-molecular-weight dextran(HMWD).METHODS: Seventy-five Sprague Dawley rats were divided randomly into five groups(n = 15 in each group): control group, immediate group, 1 h group,3 h group, and 6 h group. A model of acute blood stasis was established via injection of HMWD into the tail vein. After performing electrocardiogram at the predetermined times according to the grouping, we collected blood and cardiac samples for hematoxylin-eosin(HE) staining and histopathological examination via transmission electron microscopy. Enzyme-linked immunosorbent assay was used to detect plasma levels of NO, AngⅡ, and fibrinogen. Real-time polymerase chain reaction was used to detect the expression of ANGPTL4 m RNA and NRG-1 m RNA. Immunohistochemical methods were used to detect PECAM-1 protein expression.RESULTS: The rat model of blood stasis showed blood retention in the capillary lumens. The ST segment showed gradual elevation, and was still elevated at 3 and 6 h after induction of blood stasis.HE staining showed myocardial cell necrosis and dissolution after modeling, along with basement membrane rupture and mitochondrial structural damage. Transmission electron microscopy showed endothelial cell swelling and an increase in absorption vesicles immediately after modeling. Endothelial cell apoptosis was increased at 3 and 6 h after modeling. Cardiac muscle fibers were disordered and intercalated discs were blurred immediately after modeling. There were massive numbers of dissolved cardiac muscle fibers, ruptured basement membranes, and mitochondrial structural damage at 3 and 6 h after modeling. NO plasma concentration was significantly reduced immediately and 1 h after modeling, while it was increased at 3 and 6 h.AngⅡ plasma concentration was decreased immediately after modeling, but increased at 1, 3, and6 h. Fibrinogen plasma concentration was significantly increased at immediate, 1, 3, and 6 h after modeling. PECAM-1 protein expression was obviously increased immediately after modeling, at 1, 6 h was found mild augment. Expression of Ang PTL4 m RNA was increased at immediate, 1, 3, and 6 h after modeling, and was found further augment at 3,and 6 h. Expression of NRG-1 m RNA was increased at immediate, 1, 3, and 6 h after modeling, and the strongest expression was at 1 h.CONCLUSION: The pathological manifestation of acute blood stasis is characterized by microvascular blood retention. Prolonged blood stasis leads to worsening endothelial cell and cardiomyocyte damage, along with imbalances in the expression of vasomotor factors and increased vascular tone.The pathological damage caused by blood stasis also promotes the expression of cell protection factors. | Feng Yu Zhang Junxiu Li Shaodan Liu Yi Zhang Yin Guo Yunxia Yang Minghui | 2017 | Journal of Traditional Chinese Medicine2017，37，6： | 3 |
| 4 | Recent progress in synthesis of lanthanide-based persistent luminescence nanoparticles显示文摘Persistent luminescence nanoparticles(PLNPs)are a kind of phosphors that can remain luminescent for seconds to several days after the stoppage of excitation.Lanthanides show the special capability to largely broaden the emission range and enhance the luminescence intensity of PLNPs due to their dense energy structure and unique electronic configurations.In the past decades,various methods have been developed for the synthesis of lanthanide-based PLNPs with excellent pe rsistent luminescence propertie s,and the lanthanide-based PLNPs are widely studied in areas including biome dicine,energy,and information storage.In this review,we summarized the research progress in the synthe sis of lanthanidebased PLNPs and outline d several typical synthesis methods.We discussed the fundamental concepts of preparation methods as well as the advantages and drawbacks of the typical synthetic approache s.Moreove r,the current challenges and the potential solutions for the development of lanthanide-based PLNP s are also discussed in an attempt to provide strate gies to further improve the optical properties of lanthanide-based PLNPs.We hope this review can contribute to the design of lanthanide-based PLNPs with desired properties and further promote their applications in biomedicine,energy,and information science. | Yurong Wei Chengxu Gong Min Zhao Lei Zhang Shaodan Yang Peixu Li Zhao Ding Quan Yuan Yanbing Yang | 2022 | Journal of Rare Earths2022，40，9： | 2 |
| 5 | Tea polyphenols inhibit the growth and angiogenesis of breast cancer xenografts in a mouse model显示文摘Objective:To investigate the anti-angiogenic effect of tea polyphenols(TPS)on breast cancer and normal tissues in a mouse model.Methods:Breast cancer was successfully implanted into 48 BALB/c mice,which were then randomly divided into a TP oral gavage group,a TP local injection group,a ginsenoside Rg3 group,and a model control group according to a random number table.The tumor inhibitory rates of each group were calculated,while microvessel density(MVD)and the expression of vascular endothelial growth factor(VEGF),basic fibroblast growth factor(bFGF),and tissue inhibitor of metalloproteinase(TIMP-2)were detected by immunohistochemistry.Results:TPs could inhibit the growth of breast cancer xenografts in the mouse model.The tumor inhibition rates of the TP oral gavage and TP local injection groups were 37.43%and 40.94%,respectively.Compared with the model control group,MVD and VEGF and bFGF expression was downregulated(all P<.05),whereas TIMP-2 expression was elevated in the TP oral gavage and TP local injection groups(P=.015 and P=.032).TPs showed no significant effect on MVD and VEGF and TIMP-2 expression in the heart,brain,and kidney of the mouse model.Conclusion:TPs can restrict the growth of breast cancer by specifically inhibiting the angiogenesis of breast tumor tissue while having little effect on the normal tissue of important organs including the heart,brain,and kidney. | Peng Lv Fengqin Shi Xinyi Chen Li Xu Chong Wang Shaodan Tian Heng Yang Li Hou | 2020 | Journal of Traditional Chinese Medical Sciences2020，7，2： | 2 |
| 6 | Organelle-inspired supramolecular nanomedicine to precisely abolish liver tumor growth and metastasis显示文摘Organelles are responsible for the efficient storage and transport of substances in living systems.A myriad of extracellular vesicles(EVs)acts as a bridge to exchange signaling molecules in cell-cell communication,and the highly dynamic tubulins and actins contribute to efficient intracellular substance transport.The inexhaustible cues of natural cargo delivery by organelles inspire researchers to explore the construction of biomimetic architectures for“smart”delivery carriers.Herein,we report a 10-hydroxycamptothecin(HCPT)-peptide conjugate HpYss that simulates the artificial EV-to-filament transformation process for precise liver cancer therapy.Under the sequential stimulus of extracellular alkaline phosphatase(ALP)and intracellular glutathione(GSH),HpYss proceeds via tandem self-assembly with a morphological transformation from nanoparticles to nanofibers.The experimental phase diagram elucidates the influence of ALP and GSH contents on the self-assembled nanostructures.In addition,the dynamic transformation of organelle-mimetic architectures that are formed by HpYss in HepG2 cells enables the efficient delivery of the anticancer drug HCPT to the nucleus,and the size-shape change from extracellular nanoparticles(50-100 nm)to intracellular nanofibers(4-9 nm)is verified to be of key importance for nuclear delivery.Nuclear targeting of HpYss amplifies apoptosis,thus significantly enhancing the inhibitory effect of HCPT(>10-fold)to HepG2 cells.Benefitting from the spatiotemporally controlled nanostructures,HpYss exhibited deep penetration,enhanced accumulation,and long-term retention in multicellular spheroid and xenograft models,potently abolishing liver tumor growth and preventing lung metastasis.We envision that our organelle-mimicking delivery strategy provides a novel paradigm for designing nanomedicine to cancer therapy. | Jie Zhan Yuhan Wang Shaodan Ma Qin Qin Ling Wang Yanbin Cai Zhimou Yang | 2022 | Bioactive Materials2022，7，3： | 1 |
| 7 | Wind Power Prediction Based on Multi-class Autoregressive Moving Average Model with Logistic Function显示文摘The seasonality and randomness of wind present a significant challenge to the operation of modern power systems with high penetration of wind generation. An effective shortterm wind power prediction model is indispensable to address this challenge. In this paper, we propose a combined model, i.e.,a wind power prediction model based on multi-class autoregressive moving average(ARMA). It has a two-layer structure: the first layer classifies the wind power data into multiple classes with the logistic function based classification method;the second layer trains the prediction algorithm in each class. This two-layer structure helps effectively tackle the seasonality and randomness of wind power while at the same time maintaining high training efficiency with moderate model parameters. We interpret the training of the proposed model as a solvable optimization problem. We then adopt an iterative algorithm with a semi-closed-form solution to efficiently solve it. Data samples from open-source projects demonstrate the effectiveness of the proposed model. Through a series of comparisons with other state-of-the-art models, the experimental results confirm that the proposed model improves not only the prediction accuracy,but also the parameter estimation efficiency. | Yunxuan Dong Shaodan Ma Hongcai Zhang Guanghua Yang | 2022 | Journal of Modern Power Systems and Clean Energy2022，10，5： | 1 |
| 8 | Blind Symbol Synchronization Based on Cyclic Prefix for OFDM Systems显示文摘 | Ma Shaodan Pan Xinyue Yang Guanghua | | 0，，04： | 1 |
| 9 | Blind symbol synchronization based on cyclic prefix for OFDM systems显示文摘 | Ma Shaodan Pan Xinyue Yang Guanghua | 2009 | IEEE Transactions on Vehicular Tech- nology2009，58，4： | 1 |
| 10 | Blind symbol synchronization based on cyclic prefix for OFDM systems显示文摘 | Ma Shaodan Pan Xinyue Yang Guanghua | 2009 | IEEE Transactions on Vehicular Technology2009，58，4： | 1 |
| 11 | Blind Symbol Synchronization Based on Cyclic Prefix for OFDM Systems显示文摘 | Ma Shaodan Pan Xinyue Yang Guanghua | 2009 | IEEE Transactions on Vehicular Technology2009，，4： | 1 |
| 12 | Outage Performance and Optimal Design of MIMO-NOMA Enhanced Small Cell Networks with Imperfect Channel-State Information显示文摘This paper focuses on boosting the performance of small cell networks(SCNs)by integrating multiple-input multiple-output(MIMO)and nonorthogonal multiple access(NOMA)in consideration of imperfect channel-state information(CSI).The estimation error and the spatial randomness of base stations(BSs)are characterized by using Kronecker model and Poisson point process(PPP),respectively.The outage probabilities of MIMO-NOMA enhanced SCNs are first derived in closed-form by taking into account two grouping policies,including random grouping and distance-based grouping.It is revealed that the average outage probabilities are irrelevant to the intensity of BSs in the interference-limited regime,while the outage performance deteriorates if the intensity is sufficiently low.Besides,as the channel uncertainty lessens,the asymptotic analyses manifest that the target rates must be restricted up to a bound to achieve an arbitrarily low outage probability in the absence of the inter-cell interference.Moreover,highly correlated estimation error ameliorates the outage performance under a low quality of CSI,otherwise it behaves oppositely.Afterwards,the goodput is maximized by choosing appropriate precoding matrix,receiver filters and transmission rates.In the end,the numerical results verify our analysis and corroborate the superiority of our proposed algorithm. | Zheng Shi Hong Wang Yaru Fu Guanghua Yang Shaodan Ma Xinrong Ye | 2021 | China Communications2021，18，10： | 0 |
| 13 | A Novel Ratiometric Fluorescent Probe for Cyanide Anion with High Selectivity and Its Application in Cell Imaging显示文摘 | FENG Yusha BAI Lifei WANG Shaodan KONG Xianyi CONG Lele ZHAO Qing YANG Qingbiao LIYaoxian | 2017 | Chemical Research in Chinese Universities2017，33，4： | 0 |
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