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| 1 | New hypothesis and treatment targets of depression:an integrated view of key findings显示文摘Major depressive disorder(MDD) is a common and devastating psychiatric disorder characterized by persistent low mood,cognitive disorder,and impaired social function. Despite its complex mechanisms,increasing evidence has identified the involvement of neurotrophic factors,inflammatory cytokines,the hypothalamuspituitary-adrenal axis,and glutamate receptors in the pathophysiology of this illness. The present review synthesizes recent research achievements to defi ne the network between different hypotheses of MDD and to understand which part is most pivotal for its pathogenesis. By integrating MDD-related signal pathways,we highlight brain-derived neurotrophic factor(BDNF) dysfunction and increased apoptosis as the fi nal common cascades,and new therapeutic strategies aiming to enhance BDNF function have been shown to exert a rapid and effective antidepressant action. | Shangli Cai Shucai Huang Wei Hao | 2015 | Neuroscience Bulletin2015，31，1： | 9 |
| 2 | Variable Selection in Logistic Regression Model显示文摘Variable selection is one of the most important problems in pattern recognition. In linear regression model, there are many methods can solve this problem,such as Least absolute shrinkage and selection operator(LASSO) and many improved LASSO methods, but there are few variable selection methods in generalized linear models. We study the variable selection problem in logistic regression model. We propose a new variable selection method – the logistic elastic net, prove that it has grouping effect which means that the strongly correlated predictors tend to be in or out of the model together. The logistic elastic net is particularly useful when the number of predictors(p) is much bigger than the number of observations(n). By contrast, the LASSO is not a very satisfactory variable selection method in the case when p is more larger than n. The advantage and effectiveness of this method are demonstrated by real leukemia data and a simulation study. | ZHANG Shangli ZHANG Lili QIU Kuanmin LU Ying CAI Baigen | 2015 | Chinese Journal of Electronics2015，24，4： | 5 |
| 3 | DESIGN EFFICIENCY FOR MINIMUM PROJECTION UNIFORMITY DESIGNS WITH TWO LEVELS显示文摘这份报纸的目的是为最小的设计一致性图案学习设计效率的问题。为有力量二的直角的数组,最小的设计一致性标准是为设计效率标准的一个好代理人的结果表演由 Cheng,邓和唐(2002 ) 求婚了。 | Hong QIN Na Z0U Shangli ZHANG | 2011 | Journal of Systems Science & Complexity2011，24，4： | 3 |
| 4 | Research Progress of Grassland Feed-animal Balance at Home and Abroad显示文摘Feed-animal balance is the key technique on the grassland ecosystem management,and attracts widespread attention in the world.Many studies have been conducted by former researchers,and most of their efforts were intended to keep the balance of feed-animal.However,there are still much more issue needed to be studied in details on the face of grassland degeneration and animal husbandry sustainable development.The author analyzed the feed-animal balance research progress,including the concept of stocking rate and its practical management techniques,especially on the stocking rate calculation methods.In addition,the social and economy effects on feed-animal balance were also discussed during the progress of improving the development of pastoral economy.In order to achieve feed-animal balance more effectively,it was concluded that the focus must be shift from only on animal number to the grassland quality,and it's necessary to strengthen market tax control. | Xiaohu MAI Yujuan ZHANG Yingjun ZHANG Shangli SHI Ding HUANG Yajun ZHANG | 2013 | Asian Agricultural Research2013，5，12： | 2 |
| 5 | High strain rate superplasticity of TiC particulate reinforced 2014 aluminum alloy composites显示文摘 | Tsunemichi Imai JianFu Mao Shangli Dong etl | 2004 | Materials Science and Engineering2004，364，： | 1 |
| 6 | Super plasticity of nitride mullite short fiber-reinforced 6061 aluminum composites显示文摘 | Mao J F Tsunemichi I Shangli D | 2003 | Scripta Materialia2003，49，11： | 1 |
| 7 | Thermal decomposition of coal fly ash by concentrated sulfuric acid and alumina extraction process based on it 显示文摘 | Bai Guanghui Qiao Yunhai Shen Bo Chen Shangli | 2011 | Fuel Processing Technology2011，92，： | 1 |
| 8 | Superplasticity evaluation in an extruded Mg–8.5Li alloy显示文摘 | ShangLi Dong Tsunemichi Imai Suk-Won Lim Naoyuki Kanetake Naobumi Saito | 2007 | Journal of Materials Science2007，，13： | 1 |
| 9 | D609 Inhibits Progression of Preexisting Atheroma and Promotes Lesion Stability in Apolipoprotein E?/? Mice: A Role of Phosphatidylcholine-Specific Phospholipase in Atherosclerosis显示文摘 | Lu Zhang Jing Zhao Le Su Bin Huang Li Wang Hua Su Yun Zhang ShangLi Zhang JunYing Miao | 2010 | Arteriosclerosis Thrombosis and Vascular Biology2010，，3： | 1 |
| 10 | Superplasticity of nitride mullite short fiber-reinforced 6061 aluminum composites 显示文摘 | Jianfu Mao Tsunemichi Imai Shangli Dong | 2003 | Scripta Materialia2003，49，11： | 1 |
| 11 | An Application of the Modified Shear Lag Model to Study the Influence of Thermal Residual Stresses on the Stiffness and Yield Strength of Short Fiber Reinforced Metal Matrix Composites显示文摘The modified shear lag model proposed recently was applied to calculate thermal residual stresses and subsequent stress distributions under tensile and compressive loadings. The expressions for the elastic moduli and the yield strengths under tensile and compressive loadings were derived which take account of thermal residual stresses. The asymmetries in the elastic modulus and the yield strength were interpreted using the derived expressions and the obtained results of the stress calculations. The model predictions have exhibited good agreements with the experimental results and also with the other theoretical | Zhonghao JIANG and Jianshe LIAN(Dept. of Materials Science and Engineering, Jilin University of Technology, Changchun 130025, China)Shangli DONG and Dezhuang YANG(School of Materials Science and Engineering, Harbin Institute of Technology, Harbin 150001, | 1999 | Journal of Materials Science & Technology1999，15，3： | 1 |
| 12 | Transient-temperature and residualstress fields in axisym metric metal components after hardening显示文摘 | Yuan Farang Wu Shangli | 1985 | Materials Science and Technology1985，1，10： | 1 |
| 13 | The effects of wihing and storage temperatures on the fermentation quality and aerobic stability of stylo silage显示文摘 | Qinghua Liu Jianguo Zhang Shangli Shi | 2011 | Animal Science Journal2011，82，： | 1 |
| 14 | Superplasticity of nitride mullite short fiber-reinforced 6061 aluminum composites显示文摘 | Mao Jianfu Tsunemichi Imai Shangli Dong | 2003 | Scripta Materialia2003，49，11： | 1 |
| 15 | Estimation by polynomial splines with variable selection in additive Cox models显示文摘 | Shangli Zhang Lichun Wang Heng Lian | 2014 | Statistics2014，，1： | 1 |
| 16 | The broad spectrum inhibitory effect study of 3rare earth salts used for microbial inoculant additive显示文摘 | Pinghui Huo Jianfeng Li Shangli Shi | 2013 | Applied Mechanics and Materials2013，310，： | 1 |
| 17 | Wide spectrum inhibitory effect study of two botanical antimicrobials to soil and air microbes显示文摘 | Pinghui Huo Jianfeng Li Shangli Shi | 2013 | Applied Mechanics and Materials2013，310，： | 1 |
| 18 | Preparation and tribological properties of potassium titanate-Ti_3C_2T_x nanocomposites as additives in base oil显示文摘A potassium titanate-Ti_3 C_2 T_x nanocomposite was synthesized using a facile, low-temperature and environmentally friendly process. The morphology and micro structure of the as-prepared samples were analyzed by means of XRD, SEM, TEM, and XPS. The tribological property of the nanocomposite as additive in base oil was evaluated. The results reveal that the in-situ formed potassium titanate nanowires with average diameter of 30 nm and the uniform distribution on the surface of Ti3 C2 Tx nanosheets.Compare to Ti_3 C_2 T_x nanosheets, the average friction coefficient and wear scar width of the oil containing potassium titanate-Ti_3 C_2 T_x nanocomposites are decreased by 4.9% and 22% under the same conditions.The excellent tribological performance is attributed to the synergic effects of the two components in the nanocomposite structure. | Xuefeng Zhang Yu Guo Yijia Li Yong Liu Shangli Dong | 2019 | Chinese Chemical Letters2019，30，2： | 1 |
| 19 | High Strain Rate Superplastieity of TiC Particulate Reinforced 2014 Aluminum Alloy Composites显示文摘 | Tsunemiehi Imai JianFu Mao Shangli Dong | 2004 | Materials Science and Engineering A2004，364，12： | 1 |
| 20 | Circulating cell-free DNA for cancer early detection显示文摘Effective screening modalities are currently available for only a small subset of cancers,and they generally have suboptimal performance with complicated procedures.Therefore,there is an urgent need to develop simple,accurate,and non-invasive methods for early detection of cancers.Genetic and epigenetic alterations in plasma circulating cell-free DNA(cfDNA)have shown the potential to revolutionize methods of early detection of cancers and facilitate subsequent diagnosis to improve survival of patients.The medical interest in cfDNA assays has been inspired by emerging single-and multi-early detection of cancers studies.This review summarizes current technological and clinical advances,in the hopes of providing insights into the development and applications of cfDNA assays in various cancers and clinical scenarios.The key phases of clinical development of biomarkers are highlighted,and the future developments of cfDNA-based liquid biopsies in early detection of cancers are outlined.It is hoped that this study can boost the potential integration of cfDNA-based early detection of cancers into the current clinical workflow. | Qiang Gao Qiang Zeng Zhijie Wang Chengcheng Li Yu Xu Peng Cui Xin Zhu Huafei Lu Guoqiang Wang Shangli Cai Jie Wang Jia Fan | 2022 | The Innovation2022，3，4： | 1 |
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