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| 1 | Antigenic variation of the human influenza A(H3N2) virus during the 2014–2015 winter season显示文摘The human influenza A(H3N2) virus dominated the 2014–2015 winter season in many countries and caused massive morbidity and mortality because of its antigenic variation. So far, very little is known about the antigenic patterns of the recent H3N2 virus. By systematically mapping the antigenic relationships of H3N2 strains isolat ed since 2010, we discov ered that two groups with obvious antigenic divergence, named SW13(A/Switzerland/9715293/2013-like strains) and HK14(A/Hong Kong/5738/2014-like strains), co-circulated during the 2014–2015 winter season. HK14 group co-circulated with SW13 in Europe and the United States during this season, while there were few strains of HK14 in China's Mainland, where SW13 has dominated since 2012. Furthermore, we found that substitutions near the receptor-binding site on hemagglutinin played an important role in the antigenic variation of both the groups. These findings provide a comprehensive understanding of the recent antigenic evolution of H3N2 virus and will aid in the selection of vaccine strains. | HUA Sha LI XiYan LIU Mi CHENG YanHui PENG YouSong HUANG WeiJuan TAN MinJu WEI HeJiang GUO JunFeng WANG DaYan WU AiPing SHU YueLong JIANG TaiJiao | 2015 | Science China(Life Sciences)2015，58，9： | 17 |
| 2 | The Influence of Phacoemulsification on Corneal Endothelia Cells at Varying Blood Glucose Levels显示文摘Purpose:To investigate the influence of phacoemulsification on corneal endothelial cells in diabetes patients and normal controls. Methods:Phacoemulsification and intraocular lens implantation were performed on 75 patients with diabetic cataract (126 eyes) who were divided into two groups: Trial group 1 (Glu≤6 mmol/L); Trial group 2 (Glu 6-10 mmol/L) and 65 nondiabetic controls (112 eyes).The density and percentage of hexagonal cells and coefficient of variation of the corneal endothelia were measured before surgery and 1 day,1 month and 3 months postoperatively. Results: There was no statistical difference in the density and percentage of hexagonal cells and coefficient of variation of the corneal endothelia prior to phacoemulsification.(P>0.05) between the three groups.The density and percentage of hexagonal cells of the corneal endothelia decreased significantly after surgery in all three groups(P<0.05),while the Coefficient of variation increased in all groups(P<0.05). The rate of loss of corneal endothelial cells in the diabetic groups was significantly higher than for the control group (P<0.05), the percentage of hexagonal cells in the diabetic groups was significantly lower than for the control group (P<0.05), and the coefficient of variation in the diabetic groups was significantly higher than for the control group (P<0.05) at 1 day, 1 month and 3 months post-operatively. There was no statistical difference between the two diabetic groups in terms of these post-operative measurements. Conclusion:The corneal endothelium of diabetic patients is more prone to damage from phacoemulsification. It is advisable to evaluate the corneal endothelium routinely prior to phacoemulsification, particularly in diabetic persons. | RuiMing Yang Xiangyin Sha Mingbing Zeng Yingqian Tan Yu Zheng Feihong Fan | 2011 | Eye Science2011，26，2： | 14 |
| 3 | Spatio-temporal patterns of satellite-derived grassland vegetation phenology from 1998 to 2012 in Inner Mongolia, China显示文摘Spatio-temporal variations of vegetation phenology, e.g. start of green-up season(SOS) and end of vegetation season(EOS), serve as important indicators of ecosystems. Routinely processed products from remotely sensed imagery, such as the normalized difference vegetation index(NDVI), can be used to map such variations. A remote sensing approach to tracing vegetation phenology was demonstrated here in application to the Inner Mongolia grassland, China. SOS and EOS mapping at regional and vegetation type(meadow steppe, typical steppe, desert steppe and steppe desert) levels using SPOT-VGT NDVI series allows new insights into the grassland ecosystem. The spatial and temporal variability of SOS and EOS during 1998–2012 was highlighted and presented, as were SOS and EOS responses to the monthly climatic fluctuations. Results indicated that SOS and EOS did not exhibit consistent shifts at either regional or vegetation type level; the one exception was the steppe desert, the least productive vegetation cover, which exhibited a progressive earlier SOS and later EOS. Monthly average temperature and precipitation in preseason(February, March and April) imposed most remarkable and negative effects on SOS(except for the non-significant impact of precipitation on that of the meadow steppe), while the climate impact on EOS was found to vary considerably between the vegetation types. Results showed that the spatio-temporal variability of the vegetation phenology of the meadow steppe, typical steppe and desert steppe could be reflected by the monthly thermal and hydrological factors but the progressive earlier SOS and later EOS of the highly degraded steppe desert might be accounted for by non-climate factors only, suggesting that the vegetation growing period in the highly degraded areas of the grassland could be extended possibly by human interventions. | SHA Zongyao ZHONG Jialin BAI Yongfei TAN Xicheng Jonathan LI | 2016 | Journal of Arid Land2016，8，3： | 13 |
| 4 | Assessing the impacts of human activities and climate variations on grassland productivity by partial least squares structural equation modeling(PLS-SEM)显示文摘The cause-effect associations between geographical phenomena are an important focus in ecological research. Recent studies in structural equation modeling(SEM) demonstrated the potential for analyzing such associations. We applied the variance-based partial least squares SEM(PLS-SEM) and geographically-weighted regression(GWR) modeling to assess the human-climate impact on grassland productivity represented by above-ground biomass(AGB). The human and climate factors and their interaction were taken to explain the AGB variance by a PLS-SEM developed for the grassland ecosystem in Inner Mongolia, China. Results indicated that 65.5% of the AGB variance could be explained by the human and climate factors and their interaction. The case study showed that the human and climate factors imposed a significant and negative impact on the AGB and that their interaction alleviated to some extent the threat from the intensified human-climate pressure. The alleviation may be attributable to vegetation adaptation to high human-climate stresses, to human adaptation to climate conditions or/and to recent vegetation restoration programs in the highly degraded areas. Furthermore, the AGB response to the human and climate factors modeled by GWR exhibited significant spatial variations. This study demonstrated that the combination of PLS-SEM and GWR model is feasible to investigate the cause-effect relation in socio-ecological systems. | SHA Zongyao XIE Yichun TAN Xicheng BAI Yongfei LI Jonathan LIU Xuefeng | 2017 | Journal of Arid Land2017，9，4： | 8 |
| 5 | Tunable Syngas Synthesis from Photocatalytic CO2 Reduction Under Visible-Light Irradiation by Interfacial Engineering显示文摘Visible-light-driven CO2 photoreduction to achieve renewable materials,such as syngas,hydrocarbons,and alcohols,is a key process that could relieve environmental problems and the energy crisis simultaneously.Reduction of syngas products with diff erent H2:CO proportions is highly expected to produce high value-added chemicals in the industry.However,the development of technologies employing long-wavelength irradiation to achieve CO2 photoreduction and simultaneous tuning of the resultant H2:CO proportion remains a challenging endeavor.In this work,we carried out interfacial engineering by designing a series of heterostructured layered double-hydroxide/MoS2 nanocomposites via electrostatic self-assembly.The syngas proportion(H 2:CO)obtained from CO2 photoreduction could be modulated from 1:1 to 9:1 by visible-light irradiation(λ>400 nm)under the control of the interface-rich heterostructures.This work provides a cost-eff ective strategy for solar-tofuel conversion in an artificial photosynthetic system and describes a novel route to produce syngas with targeted proportions. | Conghui Qiu Sha Bai Wenjing Cao Ling Tan Junyan Liu Yufei Zhao Yu-Fei Song | 2020 | Transactions of Tianjin University2020，26，5： | 6 |
| 6 | TsCl-promoted sulfonylation of quinoline N-oxides with sodium sulfinates in water显示文摘An eco-friendly protocol for the synthesis of various 2-sulfonyl quinolines/pyridines through sulfonylation of heteroaromatic N-oxides with sodium sulfinates in water at ambient temperature under metal-and oxidant-free conditions has been developed.The mild reaction conditions,high reaction efficiency,operational simplicity,short reaction time and remarkable functional-group compatibility make the developed protocol very attractive for the preparation of 2-sulfonyl N-heteroaromatic compounds. | Sha Peng Yan-Xi Song Jun-Yi He Shan-Shan Tang Jia-Xi Tan Zhong Cao Ying-Wu Lin Wei-Min He | 2019 | Chinese Chemical Letters2019，30，12： | 5 |
| 7 | The potential value of microRNA-4463 in the prognosis evaluation in hepatocellular carcinoma显示文摘The purpose of this study is to measure the expression of microRNA-4463 and microRNA-6087 between normal persons and patients with hepatocellular carcinoma(HCC),and to clarify the meaning of them in the prognosis evaluation in HCC.Forty-five samples from healthy people and patients,who had been diagnosed with hepatocellular carcinoma before any treatment,were collected to study respectively.Real-time PCR was used to detect the expression of miRNA-4463 and miRNA-6087 in the serum of control group and hepatocellular carcinoma patients.The expression of miR-4463 in the serum of HCC patients was significantly higher than that in control group(P<0.05),and the expression level was independent of gender,tumor size,cell types,stages,alanine aminotransferase(ALT),aspartate aminotransferase(AST),total bilirubin(TBIL)and HBsAg status(P>0.05).But there was a significant difference of different level of AFP in HCC(P<0.05),and the difference between the group of AFP lower than 400 ug/l and the control group is statistically significant(P<0.05).Besides,the survival time had showed a significant difference at the high and low expression levels(P<0.05).But the expression level of miRNA-6087 was no difference in HCC and control group.The disorder of miRNA-4463 occurred in HCC,even the AFP level doesn’t rises.What’s more,patients who get the high level of miRNA-4463 seem to have a shorter survival time.And it contributes great to the prognostic evaluation.This is the first study to illustrate the potential significance of miRNA-4463 in the prognosis in HCC. | Tian Hu Jincheng Li Chuhong Zhang Xiu lv Sai Li Sha He Hanxing Yan Yixi Tan Mingsheng Lei Meiling Wen Jianhong Zuo | 2017 | Genes & Diseases2017，4，2： | 3 |
| 8 | The role of hypoxia-inducible factors in tumor angiogenesis and cell metabolism显示文摘Hypoxia-inducible factor(HIF)is a main heterodimeric transcription factor that regulates the cellular adaptive response to hypoxia by stimulating the transcription of a series of hypoxia-inducible genes.HIF is frequently upregulated in solid tumors,and the overexpression of HIF can promote tumor progression or aggressiveness by blood vessel architecture and altering cellular metabolism.In this review,we focused on the pivotal role of HIF in tumor angiogenesis and energy metabolism.Furthermore,we also emphasized the possibility of HIF pathway as a potential therapeutic target in cancer. | Xiu Lv Jincheng Li Chuhong Zhang Tian Hu Sai Li Sha He Hanxing Yan Yixi Tan Mingsheng Lei Meiling Wen Jianhong Zuo | 2017 | Genes & Diseases2017，4，1： | 3 |
| 9 | Low-frequency repetitive transcranial magnetic simulation prevents chronic epileptic seizure显示文摘Although low-frequency repetitive transcranial magnetic simulation can potentially treat epilepsy,its underlying mechanism remains unclear.This study investigated the influence of low-frequency repetitive transcranial magnetic simulation on changes in several nonlinear dynamic electroencephalographic parameters in rats with chronic epilepsy and explored the mechanism underlying repetitive transcranial magnetic simulation-induced antiepileptic effects.An epilepsy model was established using lithium-pilocarpine intraperitoneal injection into adult Sprague-Dawley rats,which were then treated with repetitive transcranial magnetic simulation for 7 consecutive days.Nonlinear electroencephalographic parameters were obtained from the rats at 7,14,and 28 days post-stimulation.Results showed significantly lower mean correlation-dimension and Kolmogorov-entropy values for stimulated rats than for non-stimulated rats.At 28 days,the complexity and point-wise correlation dimensional values were lower in stimulated rats.Low-frequency repetitive transcranial magnetic simulation has suppressive effects on electrical activity in epileptic rats,thus explaining its effectiveness in treating epilepsy. | Yinxu Wang Xiaoming Wang Sha Ke Juan Tan Litian Hu Yaodan Zhang Wenjuan Cui | 2013 | Neural Regeneration Research2013，8，27： | 2 |
| 10 | Scaled-up synthesis of defect-rich layered double hydroxide monolayers without organic species for efficient oxygen evolution reaction显示文摘The scaled-up synthesis of organic-free monolayer nanomaterials is highly desirable,especially in obtaining green energy by electrocatalysis.In this study,a method for the scaled-up synthesis of the series of monolayer layered double hydroxides(LDHs)without the addition of organic solvents is reported via the separate nucleation and aging steps process.The resulting monolayer LDHs with the thicknesses of less than 1 nm showed a narrow thickness distribution.X-ray absorption fine-structure revealed that monolayer NiFe-LDH nanosheets have a number of oxygen and metal vacancies defects.As a practical application,monolayer NiFe-LDH nanosheets containing defects showed an enhanced electrocatalytic water oxidation activity compared with that of bulk NiFe-LDH.Density functional theory calculations uncovered that excellent catalytic activity is attributed to vacancies defects.The proposed method is an economical and universally applicable strategy for the scaled-up production of monolayer LDHs. | Haoyuan Chi Jingwen Dong Tian Li Sha Bai Ling Tan Jikang Wang Tianyang Shen Guihao Liu Lihong Liu Luyi Sun Yufei Zhao Yu-Fei Song | 2022 | Green Energy & Environment2022，7，5： | 2 |
| 11 | Quantitative detection of ING1 mRNA under different gene regulation based on molecular beacon显示文摘The effects of drug treatment, gene transfection, and p53 RNA interference (RNAi) on level of ING1 mRNA in tumor cells were quantitatively detected with the help of ING1 molecular beacon (MB)/cRNA standard curve based on MB detection technology. Results showed that the level of ING1 mRNA could be upregulated by 5-FU treatment or ING1 transfection in low expression cell line of MCF-7 and be inhibited by silencing p53 with RNAi technology in normal expression cell line of CNE2. The level of ING1 varied from 7.7×10?16 to 53.4× 10?16 mol/μg total RNA of tumor cells. The results not only provided evidence for the regulation effects of gene expression but also were applied to investigat- ing the interaction of multigenes on signal transduc- tion pathway. | LIU Bin1,2,3,4, WANG Kemin1,2,3,4, XIAO Zhiqiang5,6, WANG Wei1,3,4, TAN Weihong1,2,3,4, SUN Yi5,6, TANG Hongxing1,3,4 & YANG Xiaohai1,3,41. State Key Laboratory of Chemo/Biosensing and Chemometrics, Hu- nan University, Changsha 410082, China 2. Life Science and Biotechnology Institute, Hunan University, Chang- sha 410082, China 3. Chemistry and Chemical Engineer College, Hunan University, Changsha 410082, China 4. Hunan Engineering Research Center for Bio-Nanotechnology, Hunan University, Changsha 410082, China 5. Medical Experiment Research Center, Xiangya Hospital, Central South University, Changsha 410008, China 6. Key Laboratory of Cancer Proteomics of Chinese Ministry of Health, Changsha 410008, China | 2006 | Chinese Science Bulletin2006，51，17： | 2 |
| 12 | Bacterial community response to petroleum contamination in brackish tidal marsh sediments in the Yangtze River Estuary, China显示文摘The brackish tidal marsh in the Baimaosha area of the Yangtze River Estuary was severely contaminated by 400 tons of heavy crude petroleum from a tanker that sank in December 2012.The spill accident led to severe environmental damage owing to its high toxicity,persistence and wide distribution.Microbial communities play vital roles in petroleum degradation in marsh sediments.Therefore,taxonomic analysis,high-throughput sequencing and 16 S rRNA functional prediction were used to analyze the structure and function of microbial communities among uncontaminated(CK),lightly polluted(LP),heavily polluted(HP),and treated(TD)sediments.The bacterial communities responded with increased richness and decreased diversity when exposed to petroleum contamination.The dominant class changed from Deltaproteobacteria to Gammaproteobacteria after petroleum contamination.The phylum Firmicutes increased dramatically in oil-enriched sediment by 75.78%,346.19%and 267.26%in LP,HP and TD,respectively.One of the suspected oil-degrading genera,Dechloromonas,increased the most in oil-contaminated sediment,by 540.54%,711.27%and 656.78%in LP,HP and TD,respectively.Spore protease,quinate dehydrogenase(quinone)and glutathione-independent formaldehyde dehydrogenase,three types of identified enzymes,increased enormously with the increasing petroleum concentration.In conclusion,petroleum contamination altered the community composition and microorganism structure,and promoted some bacteria to produce the corresponding degrading enzymes.Additionally,the suspected petroleum-degrading genera should be considered when restoring oil-contaminated sediment. | Min Wang Chenyan Sha Jian Wu Jinghua Su Jianqiang Wu Qing Wang Juan Tan Shenfa Huang | 2021 | Journal of Environmental Sciences2021，33，1： | 2 |
| 13 | Synthesis and electrocatalytic applications of flower-like motifs and associated composites of nitrogen-enriched tungsten nitride(W2N3)显示文摘We have sought to improve the electrocatalytic performance of tungsten nitride through synthetic control over chemical composition and morphology.In particular,we have generated a thermodynamically unstable but catalytically promising nitrogen-rich phase of tungsten via a hydrothermal generation of a tungsten oxide intermediate and subsequent annealing in ammonia.The net product consisted of three-dimensional(3D)micron-scale flower-like motifs of W2N3;this architecture not only evinced high structural stability but also incorporated the favorable properties of constituent two-dimensional nanosheets.From a performance perspective,as-prepared 3D W2N3 demonstrated promising hydrogen evolution reaction(HER)activities,especially in an acidic environment with a measured overpotential value of−101 mV at a current density of 10 mA/cm^2.To further enhance the electrocatalytic activity,small amounts of precious metal nanoparticles(such as Pt and Au),consisting of variable sizes,were uniformly deposited onto the underlying 3D W2N3 motifs using a facile direct deposition method;these composites were applied towards the CO2 reduction reaction(CO2RR).A highlight of this series of experiments was that Au/W2N3 composites were found to be a much more active HER(as opposed to either a CO2RR or a methanol oxidation reaction(MOR))catalyst. | Sha Tan Brian M.Tackett Qun He Ji Hoon Lee Jingguang G.Chen Stanislaus S.Wong | 2020 | Nano Research2020，13，5： | 2 |
| 14 | Sphingosine kinase 1 promotes growth of glioblastoma by increasing inflammation mediated by the NF-κB/IL-6/STAT3 and JNK/PTX3 pathways显示文摘Glioblastoma(GBM)is the most challenging malignant tumor of the central nervous system because of its high morbidity,mortality,and recurrence rate.Currently,mechanisms of GBM are still unclear and there is no effective drug for GBM in the clinic.Therefore,it is urgent to identify new drug targets and corresponding drugs for GBM.In this study,in silico analyses and experimental data show that sphingosine kinase 1(SPHK1)is up-regulated in GBM patients,and is strongly correlated with poor prognosis and reduced overall survival.Overexpression of SPHK1 promoted the proliferation,invasion,metastasis,and clonogenicity of GBM cells,while silencing SPHK1 had the opposite effect.SPHK1 promoted inflammation through the NF-κB/IL-6/STAT3 signaling pathway and led to the phosphorylation of JNK,activating the JNK-JUN and JNK-ATF3 pathways and promoting inflammation and proliferation of GBM cells by transcriptional activation of PTX3.SPHK1 interacted with PTX3 and formed a positive feedback loop to reciprocally increase expression,promote inflammation and GBM growth.Inhibition of SPHK1 by the inhibitor,PF543,also decreased tumorigenesis in the U87-MG and U251-MG SPHK1 orthotopic mouse models.In summary,we have characterized the role and molecular mechanisms by which SPHK1 promotes GBM,which may provide opportunities for SPHK1-targeted therapy. | Wan Li Hongqing Cai Liwen Ren Yihui Yang Hong Yang Jinyi Liu Sha Li Yizhi Zhang Xiangjin Zheng Wei Tan Guanhua Du Jinhua Wang | 2022 | Acta Pharmaceutica Sinica B2022，12，12： | 2 |
| 15 | Genome-wide Association and Follow-Up Replication Studies Identified ADAMTS18 and TGFBR3 as Bone Mass Candidate Genes in Different Ethnic Groups显示文摘 | Dong-Hai Xiong Xiao-Gang Liu Yan-Fang Guo Li-Jun Tan Liang Wang Bao-Yong Sha Zi-Hui Tang Feng Pan Tie-Lin Yang Xiang-Ding Chen Shu-Feng Lei Laura M. Yerges Xue-Zen Zhu Victor W. Wheeler Alan L. Patrick ClareAnn H. Bunker Yan Guo Han Yan Yu-Fang Pei Yin-Pi | 2009 | The American Journal of Human Genetics2009，，3： | 1 |
| 16 | Simulating multiphase flow in a two-stage pusher centrifuge using computational fluid dynamics显示文摘二阶段的 pusher 离心机的设计很快发展了,但是在他们的实践后面的理论的好理解是一个长期的问题。更好理解离心的过滤器过程,计算液体动力学(CFD ) 软件程序流畅被用来为三维的几何学建模并且基于 Euler-Euler,动人的网孔,动态网孔和多孔的媒介模仿多相的流动模型。模拟正切的速度是比为僵硬身体的运动的那些小一些的。在稳定的流动区域,光线的速度在对理论数据的好同意。另外,稳固的集中分发与试验性的数据被获得并且也出现了好同意。这些结果证明这个模拟方法能是一个有效工具优化二阶段的 pusher 离心机的设计。 | Chong PANG Wei TAN Endian SHA Yuanqing TAO Liyan LIU | 2012 | Frontiers of Chemical Science and Engineering2012，6，3： | 1 |
| 17 | Mapping Domain- and Age-Specific Functional Brain Activity for Children’s Cognitive and Affective Development显示文摘The human brain undergoes rapid development during childhood,with significant improvement in a wide spectrum of cognitive and affective functions.Mapping domain-and age-specific brain activity patterns has important implications for characterizing the development of children’s cognitive and affective functions.The current mainstay of brain templates is primarily derived from structural magnetic resonance imaging(MRI),and thus is not ideal for mapping children’s cognitive and affective brain development.By integrating task-dependent functional MRI data from a large sample of 250 children(aged 7 to 12)across multiple domains and the latest easy-to-use and transparent preprocessing workflow,we here created a set of age-specific brain functional activity maps across four domains:attention,executive function,emotion,and risky decision-making.Moreover,we developed a toolbox named Developmental Brain Functional Activity maps across multiple domains that enables researchers to visualize and download domain-and age-specific brain activity maps for various needs.This toolbox and maps have been released on the Neuroimaging Informatics Tools and Resources Clearinghouse website(http://gffzza9adc041c78b4b3bh5n96u090quu566pw.ffgz.tsg.suse.edu.cn/projects/dbfa).Our study provides domain-and age-specific brain activity maps for future developmental neuroimaging studies in both healthy and clinical populations. | Lei Hao Lei Li Menglu Chen Jiahua Xu Min Jiang Yanpei Wang Linhua Jiang Xu Chen Jiang Qiu Shuping Tan Jia-Hong Gao Yong He Sha Tao Qi Dong Shaozheng Qin | 2021 | Neuroscience Bulletin2021，37，6： | 1 |
| 18 | Effect of cooling rate on phosphorus segregation behavior and the corresponding precipitation of γ’’ and γ’ phases in IN718 alloy显示文摘Effect of segregation behaviors of P at different cooling rates on the precipitation of γ' and γ' phases and the corresponding strength are investigated. The precipitation of γ' and γ' phases during cooling is sensi-tive to P concentration. With increasing the concentration of Pf the amount of γ' and γ' particles increases after air cooling. With decreasing the cooling rate, the accelerating effect of P on the precipitation of γ' and γ' phases decreased first and then increased, which demonstrates the concentration of P dissolved in the grain interior decreases first and then increases. The different effects of P on γ'and γ' phases with different cooling rates were analyzed by the kinetic characteristic of nonequilibrium grain-boundary seg-regation. The characteristic of nonequilibrium grain-boundary segregation of P in superalloy is further confirmed, and the phenomenon caused by critical cooling rate is captured. | Anwen Zhang Sha Zhang Fang Liu Feng Qi Xiaoyu Yao Yuanguo Tan Dan Jia Wenru Sun | 2019 | Journal of Materials Science & Technology2019，35，7： | 1 |
| 19 | Predicting pedestrian counts in crowded scenes with rich and high-dimension al features 显示文摘 | Zhang J Tan B Sha F | 2011 | IEEE Transitions on Intelligent Transportation Systems2011，12，4： | 1 |
| 20 | Geoscience model service integrated workflow for rainstorm waterlogging analysis显示文摘This paper proposed a geoscience model service integrated workflowbased rainstorm waterlogging analysis method to overcome the defects of conventional waterlogging analysis systems.In this research,we studied a general OGC WPS service invoking strategy,an automatic asynchronous invoking mechanism of WPS services in the BPEL workflow,and a distributed waterlogging analysis services integrated workflow to realize the reconstruction of a waterlogging analysis model based on the proposed method.The proposed method can make use of the flexible adjustment capability of the workflow and not only overcomes the inherent defects of conventional geoscience analysis methods but also realizes the integration and calculation of distributed geospatial data,models and computing resources automatically.The method has better construction convenience,execution reliability,extensibility and intelligence potential than a conventional method and has important value for dealing with more natural disasters and environmental challenges. | Xicheng Tan Jingguo Jiao Nengcheng Chen Fang Huang Liping Di Jinchuan Wang Zongyao Sha Jin Liu | 2021 | International Journal of Digital Earth2021，14，7： | 1 |
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