|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Effectiveness of very low-volume preparation for colonoscopy:A prospective, multicenter observational study显示文摘BACKGROUND The effectiveness of colonoscopy strictly depends on adequate bowel cleansing.Recently,a 1 L polyethylene glycol plus ascorbate(PEG-ASC)solution(Plenvu;Norgine,Harefield,United Kingdom)has been introduced on the evidence of three phase-3 randomized controlled trials,but it had never been tested in the real-life.AIM To assess the effectiveness and tolerability of the 1 L preparation compared to 4 L and 2 L-PEG solutions in a real-life setting.METHODS All patients undergoing a screening or diagnostic colonoscopy after a 4,2 or 1 L PEG preparation,were consecutively enrolled in 5 Italian centers from September 2018 to February 2019.The primary endpoints of the study were the assessment of bowel cleansing success and high-quality cleansing of the right colon.The secondary endpoints were the evaluation of tolerability,adherence and safety of the different bowel preparations.Bowel cleansing was assessed through the Boston Bowel Preparation Scale.Adherence was defined as consumption of at least 75%of each dose,while tolerability was evaluated through a semiquantitative scale.Safety was systematically monitored through adverse events reporting.RESULTS Overall,1289 met the inclusion criteria and were enrolled in the study.Of these,490 patients performed a 4 L-PEG preparation(Selgesse^■),566 a 2 L-PEG cleansing(Moviprep^■or Clensia^■)and 233 a 1 L-PEG preparation(Plenvu^■).Bowel cleansing by Boston Bowel Preparation Scale was 6.5±1.5 overall and 6.3±1.5,6.2±1.5,7.3±1.5(P<0.001)in the subgroups of 4 L,2 L and 1 L-PEG preparation,respectively.Cleansing success was achieved in 72.4%,74.1%and 90.1%(P<0.001),while a high-quality cleansing of the right colon in 15.9%,12.0%and 41.4%(P<0.001)for 4 L,2 L and 1 L-PEG preparation groups,respectively.The 1 L preparation was the most tolerated compared to the 2 and 4 L-PEG solutions in the absence of serious adverse events within any of the three groups.Multiple regression models confirmed 1 L PEG-ASC preparation as an independent predictor of overall cleansing success,high-quality cleansing of the right colon and of tolerability.CONCLUSION This study supports the effectiveness and tolerability of 1 L PEG-ASC,also showing it is an independent predictor of overall cleansing success,high-quality cleansing of the right colon and of tolerability. | Marcello Maida Emanuele Sinagra Gaetano Cristian Morreale Sandro Sferrazza Giuseppe Scalisi Dario Schillaci Marco Ventimiglia Fabio Salvatore Macaluso Giovanni Vettori Giuseppe Conoscenti Concetta Di Bartolo Serena Garufi Domenico Catarella Michele Manganaro Clara Maria Virgilio Salvatore Camilleri | 2020 | World Journal of Gastroenterology2020，26，16： | 2 |
| 2 | Contribution offrontal cerebral blood flow measured by (99m) tc-bicisate spectand executive function deficits to predicting treatment outcome inalcohol-dependent patients显示文摘 | Noel X Sferrazza R Van Der Linden M | 2002 | Alcohol Alcohol2002，37，4： | 1 |
| 3 | Sonogashira cross-coupling of arenediazonium salts显示文摘 | Fabrizi G Goggiamani A Sferrazza A | | 0，，： | 1 |
| 4 | Can lung ultrasound replace chest ra-diography for the diagnosisof pneumonia in hospitalized children? 显示文摘 | Reali F Sferrazza Papa GF Carlucci P | 2014 | Respiration2014，88，2： | 1 |
| 5 | Fronto-limbic disconnection in bipolar disorder显示文摘 | Radaelli D Sferrazza Papa G Vai B | 2014 | Eur psychiatry2014，，： | 1 |
| 6 | 显示文摘 | Carbone E A D Boucher N Sferrazza M | 2010 | Surface and Interface Analysis2010，42，67： | 1 |
| 7 | FokI polymorphism of the vitamin D receptor gene corre lates with parameters of bone mass and turnover in a female population of the Italian island of Lampe- dusa显示文摘 | Falchetti A Sferrazza C Cepollaro C | 2007 | CalcifTissueInt2007，80，1： | 1 |
| 8 | Vohwinkel syndrome: treatment of pseudo-ainhum 显示文摘 | Basosett F Tiengo C Sferrazza R | 2010 | Dermatol2010，49，1： | 1 |
| 9 | Can Lung Ultrasound Replace Chest Radiography for the Diagnosis of Pneumonia in Hospitalized Children?显示文摘 | Reali F Sferrazza Papa GF Carlucci P | 2014 | Respiration2014，88，2： | 1 |
| 10 | Wide-band linear phase SAW filter design using slanted transducer fingers显示文摘 | CAMPBELL C K YE Yang-lin SFERRAZZA P J J | 1982 | IEEE Transactions on Sonics and Ultrasonics1982，29，4： | 1 |
| 11 | Two novel mutations at exon 8 of the Sequestosome 1(SQSTM1)gene in an Italian series of patients affected by Paget's disease of bone(PDB)显示文摘 | Falchetti A Di Stefano M Marini F Del Monte F Mavilia C Sttigoli D De Feo M L lsaia G Masi L Amedei A Cioppi F Ghinoi V Bongi S M Di Fede G Sferrazza C Rini G B Melchiorre D MatucciCerinic M Brandi M L | | 0，，06： | 1 |
| 12 | Can lung ultrasound replace chest radiography for the diagnosis of pneumonia in hospitalized children显示文摘 | Reali F Sferrazza PG Carlucci P | 2014 | Respiration2014，88，2： | 1 |
| 13 | Aerosol therapy during mechanical ventilation: an international survey显示文摘 | Ehrmann S Roche-Campo F Sferrazza PG | 2013 | Intensive Care Med2013，39，6： | 1 |
| 14 | Asthma and respiratory physiology:putting lung function into perspective显示文摘 | Sferrazza PGF Pellegrino GM Pellegrino R | 2014 | Respirology2014，19，7： | 1 |
| 15 | Therapeutic strategies for gastroenteropancreatic neuroendocrine neoplasms: State-of-the-art and future perspectives显示文摘Although gastroenteropancreatic neuroendocrine neoplasms(GEP-NENs)have always been considered rare tumors,their incidence has risen over the past few decades.They represent a highly heterogeneous group of neoplasms with several prognostic factors,including disease stage,proliferative index(Ki67),and tumor differentiation.Most of these neoplasms express somatostatin receptors on the cell surface,a feature that has important implications in terms of prognosis,diagnosis,and therapy.Although International Guidelines propose algorithms aimed at guiding therapeutic strategies,GEP-NEN patients are still very different from one another,and the need for personalized treatment continues to increase.Radical surgery is always the best option when feasible;however,up to 80%of cases are metastatic upon diagnosis.Regarding medical treatments,as GEP-NENs are characterized by relatively long overall survival,multiple therapy lines are adopted during the lifetime of these patients,but the optimum sequence to be followed has never been clearly defined.Furthermore,although new molecular markers aimed at predicting the response to therapy,as well as prognostic scores,are currently being studied,their application is still far from being part of daily clinical practice.As they represent a complex disease,with therapeutic protocols that are not completely standardized,GEP-NENs require a multidisciplinary approach.This review will provide an overview of the available therapeutic options for GEP-NENs and attempts to clarify the possible approaches for the management of these patients and to discuss future perspectives in this field. | Elettra Merola Andrea Michielan Umberto Rozzanigo Marco Erini Sandro Sferrazza Stefano Marcucci Chiara Sartori Chiara Trentin Giovanni de Pretis Franca Chierichetti | 2022 | World Journal of Gastrointestinal Surgery2022，14，2： | 1 |
| 16 | Vohwinkel syndrome: treatment of pseudo-ainhum显示文摘 | Bassetto F Tiengo C Sferrazza R | 2010 | Int J Dermatol2010，49，1： | 1 |
| 17 | Neutron Refleetivity Study of the Adsorption of Beta-Laetoglobulin at a Hydrophilic Solid/Liquid Interface 显示文摘 | MARSH R J JONES R A L SFERRAZZA M | 1999 | J Colloid Interf Sci1999，218，1： | 1 |
| 18 | Primary versus ternary adsorption of proteins onto PEG brushes显示文摘 | HALPERIN G F SCHILLIER A SFERRAZZA M | 2007 | Langmuir2007，23，21： | 1 |
| 19 | Vohwinkel syndrome: treatment of pseudo- ainhum 显示文摘 | Bassetto F Tiengo C Sferrazza R | 2010 | Int J Dermatol2010，49，1： | 1 |
| 20 | Management of antiplatelet or anticoagulant therapy in endoscopy: A review of literature显示文摘Endoscopic procedures hold a basal risk of bleeding that depends on the type of procedure and patients’comorbidities.Moreover,they are often performed in patients taking antiplatelet and anticoagulants agents,increasing the potential risk of intraprocedural and delayed bleeding.Even if the interruption of antithrombotic therapies is undoubtful effective in reducing the risk of bleeding,the thromboembolic risk that follows their suspension should not be underestimated.Therefore,it is fundamental for each endoscopist to be aware of the bleeding risk for every procedure,in order to measure the risk-benefit ratio for each patient.Moreover,knowledge of the proper management of antithrombotic agents before endoscopy,as well as the adequate timing for their resumption is essential.This review aims to analyze current evidence from literature assessing,for each procedure,the basal risk of bleeding and the risk of bleeding in patients taking antithrombotic therapy,as well as to review the recommendation of American society for gastrointestinal endoscopy,European society of gastrointestinal endoscopy,British society of gastroenterology,Asian pacific association of gastroenterology and Asian pacific society for digestive endoscopy guidelines for the management of antithrombotic agents in urgent and elective endoscopic procedures. | Marcello Maida Sandro Sferrazza Carlo Maida Gaetano Cristian Morreale Alessandro Vitello Giovanni Longo Vincenzo Garofalo Emanuele Sinagra | 2020 | World Journal of Gastrointestinal Endoscopy2020，12，6： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员