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| 1 | Outcome in obscure gastrointestinal bleeding after capsule endoscopy显示文摘AIM: To investigate the clinical impact of capsule endoscopy(CE) after an obscure gastrointestinal bleeding(OGIB) episode, focusing on diagnostic work-up, followup and predictive factors of rebleeding. METHODS: Patients who were referred to Hospital del Mar(Barcelona, Spain) between 2007 and 2009 for OGIB who underwent a CE were retrospectively analyzed. Demographic data, current treatment with non-steroid antiinflammtory drugs or anticoagulant drugs, hemoglobin levels, transfusion requirements, previous diagnostic tests for the bleeding episode, as well as CE findings(significant or non-significant), work-up and patient out-comes were analyzed from electronic charts. Variables were compared by χ 2 analysis and Student t test. Risk factors of rebleeding were assessed by Log-rank test, Kaplan-Meier curves and Cox regression model. RESULTS: There were 105 patients [45.7% women, median age of 72 years old(interquartile range 56-79)] and a median follow-up of 326 d(interquartile range 123-641) included in this study. The overall diagnostic yield of CE was 58.1%(55.2% and 63.2%, for patients with occult OGIB and overt OGIB, respectively). In 73 patients(69.5%), OGIB was resolved. Multivariate analysis showed that hemoglobin levels lower than 8 g/dL at diagnosis [hazard ratios(HR) = 2.7, 95%CI: 1.9-6.3], patients aged 70 years and above(HR = 2.1, 95%CI: 1.2-6.1) and significant findings in CE(HR = 2.4, 95%CI: 1.1-5.8) were independent predictors of rebleeding. CONCLUSION: One third of the patients presented with rebleeding after CE; risk factors were hemoglobin levels < 8 g/dL, age ≥ 70 years or the presence of significant lesions. | Alex Caas-Ventura Lucia Márque Xavier Bessa Josep Maria DedeuDepartment of Gastroenterology Hospital del Mar Research Institute Pompeu Fabra University Marc Puigvehí Sílvia Delgado-Aros Ines Ana Ibáez Agustin Seoane Luis Barranco Felipe Bory Montserrat Andreu Begoa González-Suárez | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，11： | 4 |
| 2 | OAZ uses distinct DNA- and protein-binding zinc fingers in separate BMP-Smad and Olf signaling pathways显示文摘 | Hata A Seoane J Lagna G Montalvo E Hemmati Brivanlou A Massague J | | 0，，： | 2 |
| 3 | P-Rexl participatesin Neuregulin-ErbB signal transduction and its expressioncorrelates with patient outcome in breast cancer 显示文摘 | Montero JC Seoane S Ocana A | 2011 | Onco-gene2011，30，9： | 1 |
| 4 | Automated criterion-based analysis for Cole parameters assessment from cerebral neonatal electrical bioimpedance spectroscopy measurements显示文摘 | Seoane F Ward L C Lindecrantz K | | 0，，8： | 1 |
| 5 | Tunable flexible artificial synapses:a new path toward a wearable electronic system显示文摘The flexible electronics has been deemed to be a promising approach to the wearable electronic systems.However,the mismatching between the existing flexible deices and the conventional computing paradigm results an impasse in this field.In this work,a new way to access to this goal is proposed by combining flexible devices and the neuromorphic architecture together.To achieve that,a high-performance flexible artificial synapse is created based on a carefully designed and optimized memristive transistor.The device exhibits high-performance which has near-linear non-volatile resistance change under 10,000 identical pulse signals within the 515%dynamic range,and has the energy consumption as low as 45 fJ per pulse.It also displays multiple synaptic plasticity features,which demonstrates its potential for real-time online learning.Besides,the adaptability by virtue of its threeterminal structure specifically contributes its improved uniformity,repeatability,and reduced power consumption.This work offers a very viable solution for the future wearable computing. | Kunlong Yang Sijian Yuan Yuxiang Huan Jiao Wang Li Tu Jiawei Xu Zhuo Zou Yiqiang Zhan Lirong Zheng Fernando Seoane | 2018 | npj Flexible Electronics2018，2，1： | 1 |
| 6 | A possible role ofneuropeptide Y,agouti-related protein and leptin receptor iso-forms in hypothalamic programming by perinatal feeding in therat显示文摘 | LOPEZ M SEOANE L M TOVAK S | 2005 | Diabetologia2005，48，1： | 1 |
| 7 | Flow cytomet- ric DNA ploidy analysis of oral cancer comparison with histologic grading显示文摘 | Seoane J Asenjo JA Bascones A | 1999 | Oral Oncol1999，35，3： | 1 |
| 8 | Involvement of hidden allergens in food allergic reactions显示文摘 | Anibarro B Seoane F J Mugica M V | 2007 | J Investig Allergol Clin Immonol2007，17，3： | 1 |
| 9 | Limitations of soil enzymes as indicators of soil pollution显示文摘 | Trasar-Cepeda C Lefos M C Seoane S | 2000 | Soil Biology & Biochemistry2000，，32： | 1 |
| 10 | Allergy to Eggs from Duck and Goose without Sensitization to Hen Egg Proteins显示文摘 | Bel6n Afiibarro Seoane FJ Concepci6n Vila | 2000 | J allergy Clin Immunol2000，105，4： | 1 |
| 11 | Treatment with fixed thyroxine doses in pregnant women with subclinical hypothyroidism显示文摘 | Seoane Cruz I Penin alvarez M Luna Cano R | 2012 | Endocfinol Nutr2012，59，5： | 1 |
| 12 | Utilization of grass silage by growing cattle:effect of a supplement containing ruminally protected amino acids 显示文摘 | VEIRA D M SEOANE J R PROULX J G | 1991 | Joumai of Animal Science1991，69，12： | 1 |
| 13 | The synthesis of 2-amino-4-aryl-3-ethoxycarbonyl-4H- naphtho pyrans revisited 显示文摘 | MARTIN N MARTINEZ-GRAU A SEOANE C | 1995 | Journal of Heterocyclic Chemistry1995，32，4： | 1 |
| 14 | Smad transcription factors显示文摘 | Massague J Seoane J Wotton D | 2005 | Genes Dev2005，19，： | 1 |
| 15 | Helicobacter pylori and gastric cancer: relationship with histological subtype and tumor location显示文摘 | Seoane A Bessa X Balleste B | 2005 | Gastroenterol Hepatol2005，28，2： | 1 |
| 16 | Ghrelin elicits a marked stimulatory effect on GH secretion in freely-moving rats显示文摘 | SEOANE LM TOVAR S BALDEELLI R | 2000 | Eur J Endocrinol2000，143，： | 1 |
| 17 | Dependence of mineralization of soil organic matter on temperature and moisture显示文摘 | Leiros M C Trasar-Cepeda C Seoane S | 1999 | Soil Biology and Biochemistry1999，31，： | 1 |
| 18 | Ethylene oxidation to acetic acid with palladium-vanadium(Ⅴ) oxide type catalysts显示文摘 | Boutry P Montarnal R | 1980 | J Catal1980，63，1： | 1 |
| 19 | Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation显示文摘 | Seoane J Le HV Shen L | 2004 | Cell2004，117，2： | 1 |
| 20 | CD4 + T-cell immu- nodeficiency is more dependent on immune activation than viral load in HIV-infected children on highly active antiretroviral thera- py显示文摘 | S Resino E Seoane MDG Gutierrez | 2006 | J AIDS Syndr2006，42，3： | 1 |
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