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| 1 | Evaluation and management of patients with refractory ascites显示文摘Some patients with ascites due to liver cirrhosis become no longer responsive to diuretics. Once other causes of ascites such as portal vein thrombosis, malignancy or infection and non-compliance with medications and low sodium diet have been excluded, the diagnosis of refractory ascites can be made based on strict criteria. Patients with refractory ascites have very poor prognosis and therefore referral for consideration for liver transplantation should be initiated. Search for reversible components of the underlying liver pathology should be undertaken and targeted therapy, when available, should be considered. Currently, serial large volume paracentesis (LVP) and transjugular intrahepatic portasystemic stent-shunt (TIPS) are the two mainstay treatment options for refractory ascites. Other treatment options are available but not widely used either because they carry high morbidity and mortality (most surgical options) rates, or are new interventions that have shown promise but still need further evaluation. In this comprehensive review, we describe the evaluation and management of patients with refractory ascites from the prospective of the practicing physician. | Bahaa Eldeen Senousy Peter V Draganov | 2009 | World Journal of Gastroenterology2009，15，1： | 14 |
| 2 | Body mass index and colon cancer screening:The road ahead显示文摘Screening for colorectal cancer(CRC) has been associated with a decreased incidence and mortality from CRC.However,patient adherence to screening is less than desirable and resources are limited even indeveloped countries.Better identification of individuals at a higher risk could result in improved screening efforts.Over the past few years,formulas have been developed to predict the likelihood of developing advanced colonic neoplasia in susceptible individuals but have yet to be utilized in mass screening practices.These models use a number of clinical factors that have been associated with colonic neoplasia including the body mass index(BMI).Advances in our understanding of the mechanisms by which obesity contributes to colonic neoplasia as well as clinical studies on this subject have proven the association between BMI and colonic neoplasia.However,there are still controversies on this subject as some studies have arrived at different conclusions on the influence of BMI by gender.Future studies should aim at resolving these discrepancies in order to improve the efficiency of screening strategies. | Kanwarpreet Tandon Mohamad Imam Bahaa Eldeen Senousy Ismail Fernando Castro | 2015 | World Journal of Gastroenterology2015，21，5： | 4 |
| 3 | Spot urinary sodium for assessing dietary sodium restriction in cirrhotic ascites显示文摘AIM: To evaluate the accuracy of spot urinary Na/K and Na/creatinine (Cr) ratios as an alternative to 24-h urinary sodium in monitoring dietary compliance in patients with liver cirrhosis and ascites treated with diuretics. METHODS: The study was carried on 40 patients with liver cirrhosis and ascites treated with diuretic therapy. Patients were divided into two groups according to 24-h urinary sodium. We measured spot urine Na/K ratio, Na/ Cr ratio and 24-h urinary sodium. Student's t test was used to compare the interval variables and χ2 test to compare the nominal variables between the two groups. Receiver operator characteristic curve was used to identify the best cutoff point for Na/K and Na/Cr ratio. RESULTS: The best cutoff point for Na/K ratio was 2.5 (P < 0.001) and area under the curve (AUC) was 0.9, and for Na/Cr ratio, the best cutoff point was 35 (P < 0.001) and AUC was 0.885. Na/K ratio showed higher sensitivity and accuracy compared to Na/Cr ratio (87.5% and 87% for Na/K ratio; 81% and 85% for Na/Cr ratio, respectively). CONCLUSION: Spot urine Na/K ratio has adequate accuracy for assessment of dietary sodium restrictioncompared with 24-h urinary sodium in patients with liver cirrhosis and ascites. | Mohammed Abdelhamid El-Bokl Bahaa Eldeen Senousy Khaled Zakaria El-Karmouty Inas El-Khedr Mohammed Sherif Monier Mohammed Sherif Sadek Shabana Hassan Shalaby | 2009 | World Journal of Gastroenterology2009，15，29： | 2 |
| 4 | Fast three dimensional AC electro-osmotic pumps with nonphotolithographic electrode patterning 显示文摘 | SENOUSY Y M HARNETT C K | 2010 | Biomicrofluidics2010，4，3： | 1 |
| 5 | Hepatotoxic effects of therapies for tuberculosis 显示文摘 | SENOUSY BE BELAL Sl DRAGANOV PV | 2010 | Nat Rev Gastroenterol Hepa- to12010，，10： | 1 |
| 6 | Phylogenetic Placement of Botryococcus braunii (Trebouxiophyceae) and Botryococcus sudeticus isolate UTEX 2629 (Chlorophyeeae)显示文摘 | Senousy H H Beakes G W Hack E | 2004 | Journal of Phycology2004，40，2： | 1 |
| 7 | Phylogenetic placement of Botuococcus braunii (Ttrbouxiophyceae) and Botryococcus sudetic- us isolate UTEX 2629 (Chlorophyeeae) 显示文摘 | Senousy H H Beakes G W Hack E | 2004 | Journal of Phycolo- gy2004，40，2： | 1 |
| 8 | Angiotensin‐Converting Enzyme Inhibition and Angiotensin AT1 Receptor Blockade Downregulate Angiotensin‐Converting Enzyme Expression and Attenuate Renal Injury in Streptozotocin‐Induced Diabetic Rats显示文摘 | Tarek K. Motawi Shohda A. El‐Maraghy Mahmoud A. Senousy | 2013 | J Biochem Mol Toxicol2013，，7： | 1 |
| 9 | Angiotensin-converting enzyme inhibition and angiotensin AT1 receptor blockade downregulate enzyme expression and attenuate renal injury in streptozotocin-induced diabetic rats 显示文摘 | Motawi T K E1-Maraghy S A Senousy M A | 2013 | J Biochem Mol Toxicol2013，27，7： | 1 |
| 10 | Hepatotoxic e{fects of therapies for tuberculosis 显示文摘 | Senousy BE Belal SI Draganov PV | 2010 | Nat Rev Gastroenterol Hepatol2010，7，10： | 1 |
| 11 | Angiotensin-converting enzyme inhibition and angiotensin ATl receptor blockade downregulate angiotensin-converting enzyme expression and attenuate renal injury in streptozotocin-induced diabetic rats显示文摘 | Motawi TK E1-Maraghy SA Senousy MA | | 0，，7： | 1 |
| 12 | Angiotensin - conver- ting enzyme inhibition and angiotensin AT1 receptor blockade down- regulate angiotensin - converting enzyme expression and attenuate renal injury in streptozotocin -induced diabetic rats显示文摘 | Motawi TK E1 - Maraghy SA Senousy MA | 2013 | J Biochem Mol Toxicol2013，27，7： | 1 |
| 13 | Phylogenetic placement of Botryococcus braunii (Ttrbouxiophyceae)and Botryococcus sudeticus isolate UTEX 2629 (Chlorophyceae)显示文摘 | Senousy H H Beakes G W Hack E | 2004 | Journal of Phycology2004，40，2： | 1 |
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