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| 1 | Prospective randomized controlled trial evaluating cap-assisted colonoscopy vs standard colonoscopy显示文摘AIM: To study the significance of cap-fitted colonoscopy in improving cecal intubation time and polyp detection rate. METHODS: This study was a prospective randomized controlled trial conducted from March 2008 to February 2009 in a tertiary referral hospital at Sydney. The primary end point was cecal intubation time and the secondary endpoint was polyp detection rate. Consecutive cases of total colonoscopy over a 1-year period were recruited. Randomization into either standard colonoscopy (SC) or cap-assisted colonoscopy (CAC) was performed after consent was obtained. For cases randomized to CAC, one of the three sizes of cap was used: D-201-15004 (with a diameter of 15.3 mm), D-201-14304 (14.6 mm) and D-201-12704 (13.0 mm). All of these caps were produced by Olympus Medical Systems, Japan. Independent predictors for faster cecal time and better polyp detection rate were also determined from this study. RESULTS: There were 200 cases in each group. There was no signif icant difference in terms of demographic characteristics between the two groups. CAC, when compared to the SC group, had no signif icant difference in terms of cecal intubation rate (96.0% vs 97.0%, P = 0.40) and time (9.94 ± 7.05 min vs 10.34 ± 6.82 min, P = 0.21), or polyp detection rate (32.8% vs 31.3%, P = 0.75). On the subgroup analysis, there was no significant difference in terms of cecal intubation time by trainees (88.1% vs 84.8%, P = 0.40), ileal intubation rate (82.5% vs 79.0%, P = 0.38) or total colonoscopy time (23.24 ± 13.95 min vs 22.56 ± 9.94 min, P = 0.88). On multivariate analysis, the independent determinants of faster cecal time were consultant-performed procedures (P < 0.001), male patients (P < 0.001), non-usage of hyoscine (P < 0.001) and better bowel preparation (P = 0.01). The determinants of better polyp detection rate were older age (P < 0.001), no history of previous abdominal surgery (P = 0.04), patients not having esophagogastroduodenoscopy in the same setting (P = 0.003), trainee-performed procedures (P = 0.01), usage of hyoscine (P = 0.01) and procedures performed for polyp follow-up (P = 0.01). The limitations of the study were that it was a single-center experience, no blinding was possible, and there were a large number of endoscopists. CONCLUSION: CAC did not signif icantly different from SC in term of cecal intubation time and polyp detection rate. | Hoi-Poh Tee Crispin Corte Hamdan Al-Ghamdi Emilia Prakoso John Darke Raman Chettiar Wassim Rahman Scott Davison Sean P Griffin Warwick S Selby Arthur J Kaffes | 2010 | World Journal of Gastroenterology2010，16，31： | 10 |
| 2 | Electromagnetic fileds of energized conductors显示文摘 | Dawalibi F P Selbi A | 1993 | IEEE Trans on PWRD1993，8，3： | 2 |
| 3 | Hidden risks associated with conventional short intermittent hemodialysis:A call for action to mitigate cardiovascular risk and morbidity显示文摘The development of maintenance hemodialysis(HD)for end stage kidney disease patients is a success story that continues to save many lives.Nevertheless,intermittent renal replacement therapy is also a source of recurrent stress for patients.Conventional thrice weekly short HD is an imperfect treatment that only partially corrects uremic abnormalities,increases cardiovascular risk,and exacerbates disease burden.Altering cycles of fluid loading associated with cardiac stretching(interdialytic phase)and then fluid unloading(intradialytic phase)likely contribute to cardiac and vascular damage.This unphysiologic treatment profile combined with cyclic disturbances including osmotic and electrolytic shifts may contribute to morbidity in dialysis patients and augment the health burdenof treatment. As such, HD patients are exposed to multiple stressors including cardiocirculatory,inflammatory, biologic, hypoxemic, and nutritional. This cascade of events can be termed thedialysis stress storm and sickness syndrome. Mitigating cardiovascular risk and morbidityassociated with conventional intermittent HD appears to be a priority for improving patientexperience and reducing disease burden. In this in-depth review, we summarize the hidden effectsof intermittent HD therapy, and call for action to improve delivered HD and develop treatmentschedules that are better tolerated and associated with fewer adverse effects. | Bernard Canaud Jeroen P Kooman Nicholas M Selby Maarten Taal Andreas Maierhofer Pascal Kopperschmidt Susan Francis Allan Collins Peter Kotanko | 2022 | World Journal of Nephrology2022，11，2： | 2 |
| 4 | Insecticidal Anthranilamide: a New Class of Potent Ryanodine Receptor Activators显示文摘 | LAHM G P SELBY T P FREUDENBERGER J H | 2005 | Bioorganic & Medicinal Chemistry Letters2005，，15： | 1 |
| 5 | Detection of coloreetal cancer cells in peripheral blood by reverse transcriptase polymerase chain reaction for cytokeratin 20 显示文摘 | Wyld D K Selby P Perren T J | 1998 | Int J Cancer1998，79，3： | 1 |
| 6 | Detection of melanoma cells in peripheral blood by means of reverse transcriptase and polymerase chain reaction 显示文摘 | Smith B Selby P Southgate J | 1991 | Lancet1991，338，8777： | 1 |
| 7 | Detection of melanoma ceils in perihperal blood by means of reverse transcriptase and polymerase chain reaction显示文摘 | Smith B Selby P Southgate J | 1991 | Lancet1991，338，8777： | 1 |
| 8 | Body burdens of lead in hypertensive nephropathy 显示文摘 | Osterloh J D Selby J V Bernard B P | 1989 | Arch Environ Health1989，44，5： | 1 |
| 9 | Insecticidal anthranilic diamides:a new class of potent ryanodine receptor activators显示文摘 | LAHM G P SELBY T P FREUDENBERGER J H | 2005 | Bioorganic & Medicinal Chemistry Letters2005，15，： | 1 |
| 10 | RynaxypyTM:a new insecticidal anthranilic diamide that acts as a potent and selective ryanodine receptor activator显示文摘 | LAHM G P STEVENSON T M SELBY T P | 2007 | Bioorg & Med Chem Lett2007，17，： | 1 |
| 11 | The incidence of colorectal cancer following a negative screening sigmoidoscopy: implications for screening interval 显示文摘 | DORIA-ROSE V P LEVIN T R SELBY J V | 2004 | Gastroenterology2004，127，3： | 1 |
| 12 | Freudenberger,insecticidal anthranilamide:anew class of potent ryanodine receptor activator显示文摘 | GEORGE P LAHM THOMAS P SELBY JOHN H | | 0，，： | 1 |
| 13 | Tumour Necrosis Factor in Man: Clinical and Biological Observations显示文摘 | Hobbs S Viner C | 1987 | Br J Cancer1987，56，： | 1 |
| 14 | Discovery of Cyantraniliprole, a Potent and Selective Anthranilic Diamide Ryano-dine Receptor with Cross-spectrum Insecticidal Activity 显示文摘 | Selby T P Lahm G P Stevenson T M | 2013 | Bioorga- nic & Medicinal Chemistry Letters2013，23，23： | 1 |
| 15 | Class Ⅰ heat shock genes hrcA and dnaK play an important role in heat shock response and response to pH and NaCl stress of group Ⅰ Clostridium botulinum ATCC 3502显示文摘 | Selby K Lindstr(o)m M Somervuo P Heap JT Minton NP Korkeala H | | 0，，： | 1 |
| 16 | The molecular detection of circulating tumor cells显示文摘 | Jobson P W M Burchill SA Selby PJ | 1995 | Br J Cancer1995，72，： | 1 |
| 17 | Progestogens of varying androgenicity and cardiovascular risk factors in postmenopausal women receiving oestrogen replacement therapy 显示文摘 | KWOK S SELBY PL MCELDUFF P | 2004 | Clin Endocrinol(Oxf)2004，61，6： | 1 |
| 18 | The potential of organic poly- mer-based hydrogen storage materials 显示文摘 | Budd P M Butler A Selbie J | 2007 | Phys Chem Chem Phys2007，9，26： | 1 |
| 19 | Facts, noise and wishful thinking:musle protein turnover in aging and human disuse at- rophy显示文摘 | Rennie M J Selby A Atherton P | 2010 | Scand J Med Sci Sports2010，20，1： | 1 |
| 20 | A comparison of in situ hybridisation, reverse transcriptase-polymerase chain reaction (RT-PCR) and in situ-RT-PCR for the detection of canine distemper virus RNA in Paget’s disease显示文摘 | Judith A Hoyland Janet A Dixon Jacqueline L Berry Michael Davies Peter L Selby Andrew P Mee | 2003 | Journal of Virological Methods2003，，2： | 1 |
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