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| 1 | Epidemiological profiles of human immunodeficiency virus and hepatitis C virus infections in Malian women:Risk factors and relevance of disparities显示文摘AIM:To document the epidemiologic patterns and risk factors of human immunodeficiency virus(HIV)and hepatitis C virus(HCV)infections in Mali in order to develop prevention means for both diseases.METHODS:Two prospective studies were conducted in Bamako in 2009 among 1000 pregnant women(i.e.,young women)who consulted six reference health centers,and in 2010,among 231 older women who attended general practice in two hospitals.Antibody tests and molecular analysis(performed only for HCV)were used to quantify the frequencies of both infections.The data were collected from patients recruited through a questionnaire.Transmission risk factors of both diseases were identified by univariate and multivariate analysis.RESULTS:HCV seroprevalence was 0.2% for young and 6.5% for older women.HIV prevalence was similar in both populations(4.1% vs 6.1%).In older women,the analysis of risk factors highlighted an association between HCV infection and episodes of hospitalization(P < 0.01).The study did not show an association between HIV infection and the variables such as hospitalization,transfusion,tattoo,dental care,and endoscopy.A significant decrease of HIV seroprevalence was detected in young women who used condoms for contraception more than for other purposes(P < 0.01).By contrast,HIV seroprevalence was significantly increased in young women using condoms mainly to prevent sexual infections rather than for contraception(P < 0.01).No HCV/HIV coinfection was detected in our study.CONCLUSION:Risk factors and epidemiologic data of HIV and HCV as well as the absence of co-infection strongly suggest epidemiological disparities between these diseases. | Nouhoum Bouare Andre Gothot Jean Delwaide Sebastien Bontems Dolores Vaira Laurence Seidel Paul Gerard Christiane Gerard | 2013 | World Journal of Hepatology2013，5，4： | 4 |
| 2 | UML&AADL'2007 grand challeoges显示文摘 | Sebastien Gerard Peter Feiler Jean - Francois RoUand | 2007 | ACM2007，4，4： | 1 |
| 3 | Carbon input to soil may decrease soil carbon content显示文摘 | SEBASTIEN F GERARD B LUC A | 2004 | Ecology Letters2004，7，： | 1 |
| 4 | Functional Specializations of Human Epidermal Langerhans Cells and CD14 + Dermal Dendritic Cells显示文摘 | Eynav Klechevsky Rimpei Morita Maochang Liu Yanying Cao Sebastien Coquery LuAnn Thompson-Snipes Francine Briere Damien Chaussabel Gerard Zurawski A. Karolina Palucka Yoram Reiter Jacques Banchereau Hideki Ueno | 2008 | Immunity2008，，： | 1 |
| 5 | 在 Malian 女人和血清学的试金表演的二张人口的 HIV 和 HCV 感染的流行显示文摘 AIM:To estimate the prevalence of human immunodeficiency virus(HIV) and hepatitis C virus(HCV) infections in women in Mali and to evaluate the performance of serological assays.METHODS:Two prospective studies were conducted in 2009 and 2010 in Mali.They concerned first,1000 pregnant women attending six reference health centers in Bamako(Malian capital) between May 26 and June 16,2009;and secondly,231 women over 50 years who consulted general practitioners of two hospitals in Bamako between October 25 and December 24,2010.Blood samples were collected and kept frozen in good condition before analysis.All samples depicted as positive using HIV/HCV enzyme immuno-assay screening assays were submitted to confirmation analysis.Molecular markers of HCV were characterized.RESULTS:The seroprevalence of HIV and HCV in the population of pregnant women was 4.1% and 0.2% respectively.Among older women the seroprevalence was higher and similar for HIV and HCV(6.1% vs 6.5%).The anti-HIV prevalence was not different in young and older women(4.1% vs 6.1%).In contrast,the anti-HCV prevalence was higher in older compared to younger women(6.5% vs 0.2%,P < 0.01).Of 2 pregnant women who were HCV seropositive,only one was polymerase chain reaction(PCR) reactive and infected by genotype 2,with a viral load of 1600 IU/mL.Regarding older women who were HCV seropositive,13 out of 15 were PCR reactive,infected by genotype 1 or 2.Globally HCV genotype 2 was predominant.The positive predictive value(PPV) measured with VIKIA HIV test in young women was 100% therefore significantly higher than the 87.5% measured in older women(P < 0.05).Conversely,the PPV measured with Monolisa HCV assay in older women was 88.2% and higher than the 14.3% measured in younger women(P < 0.01).CONCLUSION:Whereas HIV prevalence was similar in both subpopulations HCV was more frequent among older women(P < 0.01).The PPV of screening assays varied with the age of the subjects. | Nouhoum Bouare Dolores Vaira Andre Gothot Jean Delwaide Sebastien Bontems Laurence Seidel Paul Gerard Christiane Gerard | 2012 | World Journal of Hepatology2012，4，12： | 1 |
| 6 | 布鲁塞尔当代收藏设计展显示文摘3月7日至11日,布鲁塞尔市中心举办了首届布鲁塞尔收藏展。与以展示20世纪中期或经典设计作品为主的传统展会不同,本次展会将焦点放在了21世纪的当代设计作品,为艺术和设计行业带来了一个全新的视角。 | Paolo Gonzato Muller Van Severen unfold Olga Engel Core Studio Caporusso Sebastien Destroyers Bullders Net Verbeke Paulin Paulin.Paulin MODE Gerard Kuijpers Collectible Design Fair 彭佳 | 2018 | 现代装饰2018，0，4： | 0 |
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