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| 1 | Pretreatment with adenosine and adenosine A1 receptor agonist protects against intestinal ischemia-reperfusion injury in rat显示文摘AIM: To examine the effects of adenosine and A1 re- ceptor activation on reperfusion-induced small intestinal injury. METHODS: Rats were randomized into groups with sham operation, ischemia and reperfusion, and systemic treatments with either adenosine or 2-chloro-N6-cyclo- pentyladenosine, A1 receptor agonist or 8-cyclopentyl- 1,3-dipropylxanthine, A1 receptor antagonist, plus ade- nosine before ischemia. Following reperfusion, contra- ctions of ileum segments in response to KCl, carbachol and substance P were recorded. Tissue myeloperoxidase, malondialdehyde, and reduced glutathione levels were measured. RESULTS: Ischemia significantly decreased both contra- ction and reduced glutathione level which were ameliora- ted by adenosine and agonist administration. Treatment also decreased neutrophil infiltration and membrane lipid peroxidation. Beneficial effects of adenosine were abolis- hed by pretreatment with A1 receptor antagonist. CONCLUSION: The data suggest that adenosine and A1 receptor stimulation attenuate ischemic intestinal in- jury via decreasing oxidative stress, lowering neutrophil infiltration, and increasing reduced glutathione content. | V Haktan Ozacmak Hale Sayan | 2007 | World Journal of Gastroenterology2007，13，4： | 3 |
| 2 | Choosing Multiple Parameters for Support Vector Machines显示文摘 | Olivier Chapelle Vladimir Vapnik Olivier Bousquet Sayan Mukherjee | 2002 | Machine Learning (-)2002，，1： | 3 |
| 3 | Nanocellulose,a versatile platform:From the delivery of active molecules to tissue engineering applications显示文摘Nanocellulose,a biopolymer,has received wide attention from researchers owing to its superior physicochemical properties,such as high mechanical strength,low density,biodegradability,and biocompatibility.Nanocellulose can be extracted from wide range of sources,including plants,bacteria,and algae.Depending on the extraction process and dimensions(diameter and length),they are categorized into three main types:cellulose nanocrystals(CNCs),cellulose nanofibrils(CNFs),and bacterial nanocellulose(BNC).CNCs are a highly crystalline and needle-like structure,whereas CNFs have both amorphous and crystalline regions in their network.BNC is the purest form of nanocellulose.The nanocellulose properties can be tuned by chemical functionalization,which increases its applicability in biomedical applications.This review highlights the fabrication of different surface-modified nanocellulose to deliver active molecules,such as drugs,proteins,and plasmids.Nanocellulose-mediated delivery of active molecules is profoundly affected by its topographical structure and the interaction between the loaded molecules and nanocellulose.The applications of nanocellulose and its composites in tissue engineering have been discussed.Finally,the review is concluded with further opportunities and challenges in nanocellulose-mediated delivery of active molecules. | Tejal V.Patil Dinesh K.Patel Sayan Deb Dutta Keya Ganguly Tuhin Subhra Santra Ki-Taek Lim | 2022 | Bioactive Materials2022，7，3： | 2 |
| 4 | An improved response surface method for the determination of failure probability and importance measures显示文摘 | Sayan Gupta C.S Manohar | 2003 | Structural Safety2003，，2： | 2 |
| 5 | An improved response surface method for the determination of failure probability and importance measures显示文摘 | SAYAN G MANOHAR C S | 2004 | Structural Safety2004，26，1： | 1 |
| 6 | Routine using pattern andperformance of diagnostic tests for tuberculosis on a universityhospital显示文摘 | Dunder D Sayan M Arsian Z | 2010 | AM J Medsci2010，339，3： | 1 |
| 7 | Choosing Multiple Parameters for Support Vector Machines显示文摘 | Olivier Chapelle Vladimir Vapnik Olivier Bousquet Sayan Mukherjee | 2002 | Machine Learning (-)2002，，1： | 1 |
| 8 | Macrolide and tetracy- cline resistance and emm type distribution of Strepto- coccus pyogenes isolates recovered from Turkish pa- tients显示文摘 | Dundar D Sayan M Tamer GS | 2010 | Microb Drug Resist2010，16，4： | 1 |
| 9 | The effectiveness of Watson's caring model on the quality of life and blood pressure of patients with hypertension显示文摘 | Eric B Sayan A Tortumluoglu G | 2003 | J Adv N URS2003，41，2： | 1 |
| 10 | The Multi- tasking Clinician: Decision Making and Cognitive De- mand during and after Team Handoffs in Emergency Care 显示文摘 | Laxmisan A Hakimzada F Sayan OR | 2007 | International Journal of Medical Informat- ics2007，76，1112： | 1 |
| 11 | An improved response surface method for the determination of failure probability and importance measures显示文摘 | Sayan Gup ta C S Manohar | 2004 | Structural Safety2004，，26： | 1 |
| 12 | Apoptin induces apoptosis by changing the equilibrium between the stability of Tap73andΔNp73isoforms through ubiquitin ligase PIR2显示文摘 | Taebunpakulm P Sayan BS Flinterman M | 2012 | Apoptosis2012，17，8： | 1 |
| 13 | p73: in silico evi dence for a putative third promoter region显示文摘 | Sayan A E Rossi M Melino G Knight R A | 2004 | Biochem Biophys Res Commun2004，313，： | 1 |
| 14 | Effects of moderate altitude on exhaled nitric oxide, erythrocytes lipid peroxidation and superoxide dismutase levels显示文摘 | Guzel NA Sayan H Erbas D | 2000 | Jpn J Physiol2000，50，2： | 1 |
| 15 | An improved response surface method for the determination of failure probability and importance measures显示文摘 | Sayan Gupta Manohar C S | 2004 | Structural Safety2004，26，2： | 1 |
| 16 | A serological diagnostic survey for Brucella canis infection in Turkish patients with Brucellosis-likesymp- toms显示文摘 | Sayan M Erdenlig S Stack J | 2011 | Jpn J Infect Dis2011，64，： | 1 |
| 17 | General ccnditions for predictivity in learning theory显示文摘 | POGGIO Tomaso RIFKIN Ryan MUKHERJEE Sayan | 2004 | Nature2004，428，： | 1 |
| 18 | p53 is cleaved by caspases generating fragments localizing to mitochondria显示文摘 | Sayan B S Sayan A E Knight R A | 2006 | J Biol Chem2006，281，19： | 1 |
| 19 | p73 induces apoptosis by different mechanisms 显示文摘 | Ramadan S Terrinoni A Catani M V Sayan A E Knight R A Mueller M | 2005 | Biochem Biophys Res Commun2005，331，： | 1 |
| 20 | Regulation of p53 expression, phosphorylation and subcellular localization by a G-protein-coupled receptor显示文摘 | Solyakov L Sayan E Riley J | 2009 | Oncogene2009，28，41： | 1 |
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