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27篇 您的检索式:作者名="Samoilova M"
    题名 作者 年代 出处 被引量
1Connexin 43 mimetic peptides inhibit spontaneous epileptiform activity in organotypic hippocampal slice cultures显示文摘Samoilova M Wentlandt K Adamchik Y 2008Exp Neurol2008,210,2:1
2Epileptiform activity in hippocampal slice cultures exposed chronically to bicuculline:increased gap junctional function and expression显示文摘Samoilova M Li J Pelletier MR 2003J Neurochem2003,86,3:1
3Epileptiform activity in hippocampal slice cultures exposed chronically to bicuculline:increased gap junctional function and expression显示文摘Samoilova M Li J Pelletier MR 2003J Neurochem2003,86,:1
4Epileptiform activity in hippocampal slice cultures exposed chronically to bicuculline:increased gap junctional function and expression显示文摘Samoilova M Li J Pelletiet MR 2003J Neurochem2003,86,7:1
5Con- nexin 43 mimetic peptides inhibit spontaneous epileptiform ac- tivity in organotypic hippocampal slice cultures显示文摘SAMOILOVA M WENTLANDT K ADAMCHIK Y 2008Exp Neurol2008,210,2:1
6Epileptiform activity in hippocampal slice cultures exposed chronically to bicuculline:increased gap junctional function and expression显示文摘Samoilova M Li J pelletier MR 2003Neurochem2003,86,2:1
7Connexin 43 mimetic peptides inhibit spontaneous epileptiform activity in organotypic hippocampal slice cultures显示文摘Samoilova M Wentlandt K Adamchik Y 2008Exp Neurol2008,210,2:1
8Two routes oftantalum-catalyzed alkene carbomagnesiation with ethyl Grignardreagents显示文摘Sultanov R M Dzhemilev U M Samoilova E V 2012Journal of Organometallic Chemistry2012,715,:1
9Chronic in vitro ketosis is neuroprotective but not anti-convulsant 显示文摘Samoilova M Weisspapir M Abdelmalik P 2010J Neurochem2010,113,4:1
10Bortezomib plus melphalan and prednisone for initial treatment of multiple my- eloma显示文摘San Miguel JF Schlag R Khuageva NK Dimopoulos MA Shpil- berg O Kropff M Spieka I Petrucci MT Palumbo A Samoilova OS Dmoszynska A Abdulkadyrov KM Schots R Jiang B Ma- teos MV Anderson KC Esseltine DL Liu K Cakana A van de Velde H Richardson PG VISTA Trial Investigators 2008N Engl J Meal2008,359,9:1
11Gap junctions in epileptogenesis:chicken or egg显示文摘 LI J 2004Epilepsy Curt2004,4,2:1
12Gap Junctions in Epileptogenesis: Chicken or Egg? 显示文摘Samoilova M Li J 2004Epilepsy Curr2004,4,2:1
13Epileptiform activity in hippocampal slice culturesexposed chronically to bicuculline : increased gapjunctional function and expression 显示文摘SAMOILOVA M LI J PELLETIER MR 2003JNeurochem2003,86,3:1
14Vascular smooth muscle and nitric oxide synthase显示文摘Buchwalow IB Podzuweit T Bocker W Samoilova VE Thomas S Wellner M 2002FASEB J2002,16,6:1
15Connexin 43 mimetic peptides inhibit spontaneous epileptiform activity in organotypie hippocampal slice cultures显示文摘Samoilova M Wentlandt K Adamchik Y 2008Exp Neurol2008,210,2:1
16General anesthetics inhibit gap junction in cultured organotypic hippocampal slices显示文摘Wentlandt K Samoilova M Carlen PL 2006Anesth Analg2006,102,6:1
17Disease modifying treatment of spinal cord injury with directly reprogrammed neural precursor cells in non-human primates显示文摘BACKGROUND The development of regenerative therapy for human spinal cord injury(SCI)is dramatically restricted by two main challenges:the need for a safe source of functionally active and reproducible neural stem cells and the need of adequate animal models for preclinical testing.Direct reprogramming of somatic cells into neuronal and glial precursors might be a promising solution to the first challenge.The use of non-human primates for preclinical studies exploring new treatment paradigms in SCI results in data with more translational relevance to human SCI.AIM To investigate the safety and efficacy of intraspinal transplantation of directly reprogrammed neural precursor cells(drNPCs).METHODS Seven non-human primates with verified complete thoracic SCI were divided into two groups:drNPC group(n=4)was subjected to intraspinal transplantation of 5 million drNPCs rostral and caudal to the lesion site 2 wk post injury,and lesion control(n=3)was injected identically with the equivalent volume of vehicle.RESULTS Follow-up for 12 wk revealed that animals in the drNPC group demonstrated a significant recovery of the paralyzed hindlimb as well as recovery of somatosensory evoked potential and motor evoked potential of injured pathways.Magnetic resonance diffusion tensor imaging data confirmed the intraspinal transplantation of drNPCs did not adversely affect the morphology of the central nervous system or cerebrospinal fluid circulation.Subsequent immunohistochemical analysis showed that drNPCs maintained SOX2 expression characteristic of multipotency in the transplanted spinal cord for at least 12 wk,migrating to areas of axon growth cones.CONCLUSION Our data demonstrated that drNPC transplantation was safe and contributed to improvement of spinal cord function after acute SCI,based on neurological status assessment and neurophysiological recovery within 12 wk after transplantation.The functional improvement described was not associated with neuronal differentiation of the allogeneic drNPCs.Instead,directed drNPCs migration to the areas of active growth cone formation may provide exosome and paracrine trophic support,thereby further supporting the regeneration processes.Vladimir P Baklaushev Oleg V Durov Vladimir A Kalsin Eugene V Gulaev Sergey V Kim Ilya L Gubskiy Veronika A Revkova Ekaterina M Samoilova Pavel A Melnikov Dzhina D Karal-Ogly Sergey V Orlov Alexander V Troitskiy Vladimir P Chekhonin Alexander V Averyanov Jan-Eric Ahlfors 2021World Journal of Stem Cells2021,13,5:1
18Epileptiform activity in hipp- ocampal slice cultures exposed chronically to bieuculline:increased gap junctional function and expression 显示文摘Samoilova M Li J Pelletier MR 2003J Neurochem2003,86,3:1
19General anesthetics inhibit gap junction communication in cultured organotypic hippocampal slices显示文摘Wentlandt K Samoilova M Carlen PL 0,,06:1
20Epileptiform activity in hipp- ocampal slice cultures exposed chronically to bicucalline: increased gap junctional function and expression 显示文摘Samoilova M Li J Pelletier MR 2003J N eurochem2003,86,:1
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