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| 1 | Physicochemical properties of β-cyclodextrin solutions and precipitates prepared from injectable vehicles显示文摘β-Cyclodextrin( β-CyD) is cyclic oligosaccharide of a glucopyranose, containing a relatively hydrophobic central cavity and hydrophilic outer surface. However, the usefulness of β-CyD is limited owing to its low aqueous solubility whereas we found that its apparent high solubility was evident in some injectable solvents including 2-pyrrolidone(PYR), Nmethyl pyrrolidone(NMP) and dimethyl sulfoxide(DMSO). Therefore, in the present study, the physicochemical properties of the 30–60% w/w β-CyD in PYR, NMP and DMSO were investigated such as viscosity, water resistant, matrix formation rate and syringeability. The higher the concentration of β-CyD resulted in the increased viscosity and the higher force and energy of syringeability. β-CyD in PYR gave the highest viscosity which contributed to the lowest syringeability while β-CyD in DMSO exhibited the highest syringeability. The β-CyD in DMSO and NMP exhibited the higher rate of matrix formation. β-CyD in PYR showed the highest water resistant for phase separation while β-CyD in NMP gave the faster de-mixing rate compared to that from PYR. The difference in physicochemical properties of β-CyD dried ppts studied by scanning electron microscope(SEM), differential scanning calorimetry(DSC), X-ray diffraction(XRD), Fourier-transform infrared spectroscopy(FT-IR) and thermogravimetric analysis(TGA) revealed that there was partial complexation of β-CyD with respective solvents. Both solution and precipitate characteristic properties will be useful for using β-CyD in further investigation as matrix material dissolved in the injectable vehicles as the in situ forming gel for periodontitis treatment. | Saia Myo Thurein Nutdanai Lertsuphotvanit Thawatchai Phaechamud | 2018 | Asian Journal of Pharmaceutical Sciences2018，13，5： | 2 |
| 2 | Short and long term clinical benefit of sirolimus-eluting stents compared to conventional bare stents for patients with acute myocardial infarction显示文摘 | Lemos PA Saia F Hofma SH | 2004 | J Am Coll Cardiol2004，43，4： | 1 |
| 3 | Sirolimus-eluting stent implantation in ST elevatioancute myocardial infarction:a clinical and anglographic study显示文摘 | Saia F Lemos PA Lee CH | 2003 | Circulation2003，108，16： | 1 |
| 4 | Diagnostic performance of standard electrocardiogram for prediction of infarct related artery and site of coronary occlusion in unselected STEMI patients undergoing primary percutaneous coronary intervention显示文摘 | Taglie-ri N Saia F Alessi L | 2014 | Eur Heart J Acute Cardiovasc Care2014，3，4： | 1 |
| 5 | 药物洗脱支架应用的长期安全性和有效性:REAL多中心注册研究的两年结果显示文摘背景:药物洗脱支架(DES)应用的长期安全性和有效性近来受到质疑。方法和结果:在2002年7月至2005年6月间,10629例应用DES(n=3064)或裸金属支架(BMS;n=7565)行择期经皮冠状动脉介入治疗的患者被纳入一项前瞻性注册研究(包括13所医院)。 | Marzocchi A. Saia F. Piovaccari G. 刘相飞 | 2007 | 世界核心医学期刊文摘(心脏病学分册)2007，，11： | 1 |
| 6 | Progressive stroke in pontine infarction显示文摘 | Saia V Pantoni L | 2009 | Acta Neurol Scand2009，120，4： | 1 |
| 7 | Long-term safetyand efficacy of drug-eluting stents:two-year results of theREAL (Registro AngiopLastiche dell'Emilia Romagna) multicenterregistry显示文摘 | Marzocchi A Saia F Piovaccari G | 2007 | Circulation2007，115，25： | 1 |
| 8 | Eroded versusruptured plaques at the culprit site of STEMI : in vivo patho-physiological features and response to primary PCI显示文摘 | SAIA F KOMUKAI K CAPODANNO D | 2015 | JACCCardiovasc Imaging2015，8，5： | 1 |
| 9 | Short-and long-term clinical benefit of sirolimus-eluting stnets compared to conventional bare stents for patients with acute myocardial infarction显示文摘 | SAIA F HOFMA S H | 2004 | J Am Coll Cardiol2004，43，4： | 1 |
| 10 | Clinical outcomes for sirolimus-eluting stent implantation and vascular brachytherapy for the treatment of in-stent restenosis 显示文摘 | Saia F Lemos P A Hoye A | 2004 | Catheter Cardiovasc Interv2004，62，3： | 1 |
| 11 | Transradial versus transfemoral intervention for acute myocardial infarction: a propensity seore-adiusted and-matched analysis from the REAL ( REgistro regionale AngiopLastiche dell Emilia Romagna) multicenter registry显示文摘 | Valgimigli M Saia F Guastaroba P | 2012 | JACC Cardiovasc lnterv2012，5，1： | 1 |
| 12 | Prognostic significance of mean platelet volume on admission in an unselected cohort of patients with non ST-segment elevation acute coronary syndrome显示文摘 | Taglieri N Saia F Rapezzi C | 2011 | Thromb Haemost2011，106，1： | 1 |
| 13 | Effect of fluvastatin on long-term outcome after coronary revascularization with stent implantation显示文摘 | Francesco Saia Pim de Feyter Patrick W. Serruys Pedro A. Lemos Chourmouzios A. Arampatzis Guy R. Hendrickx Nicholas Delarche Dick Goedhart Emmanuel Lesaffre Angelo Branzi | 2004 | The American Journal of Cardiology2004，，1： | 1 |
| 14 | Effect of fluvastatin on long - term outcome after coronary revascularization with stent implantation显示文摘 | De Feyter P Serruys PW | 2004 | Am J Cardiol2004，93，： | 1 |
| 15 | Heparin attenuates TNF-alpha induced inflammatory response through a CDllb dependent mechanism显示文摘 | SAIAS A SANS M SORIANO A | 2000 | Gut2000，47，1： | 1 |
| 16 | Inhibition of p21-ac- tivated kinase 6 (PAK6) increases radiosensitivity of prostate eanc-er cells显示文摘 | Zhang M Siedow M Saia G Chakravarti A | 2010 | Prostate2010，70，8： | 1 |
| 17 | Sirolimus-eluting stent implantation in ST-elevation acute myocardial infarction:a clinical and angiographic study显示文摘 | Saia F Lemos PA Lee CH | 2003 | Circulation2003，108，16： | 1 |
| 18 | Lescol intervention prevention study (LIPS) investigatorsl Effect of fiuvastatin on long term outcome after coronary revascularization with stent imp lantation 显示文摘 | Saia F De Feyter P Serruys PW | 2004 | Am J Cardiol2004，93，： | 1 |
| 19 | Short and long term clinical benefit of sirolimus - eluting stents compared to conventional bare stents for patients with acute myocardial infarction 显示文摘 | Lemos PA Saia F Hofma SH | 2004 | J Am Coll Cardiol2004，43，： | 1 |
| 20 | The role of the neonatal nurse practitioner in post NICU follow-up显示文摘 | Beal J A Tiani T B Saia T A et at | 1999 | J Perinat Neonatal Nurs1999，13，1： | 1 |
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