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| 1 | Folic acid supplementation inhibits recurrence of colorectal adenomas:A randomized chemoprevention trial显示文摘AIM: To determine whether folic acid supplementation will reduce the recurrence of colorectal adenomas, the precursors of colorectal cancer, we performed a double-blind placebo-controlled trial in patients with adenomatous polyps. METHODS: In the current double-blind, placebo-controlled trial at this VA Medical Center, patients with colorectal adenomas were randomly assigned to receive either a daily 5 mg dose of folic acid or a matched identical placebo for 3 years. All polyps were removed at baseline colonoscopy and each patient had a follow up colonoscopy at 3 years. The primary endpoint was a reduction in the number of recurrent adenomas at 3 years. RESULTS: Of 137 subjects, who were eligible after confirmation of polyp histology and run-in period to conform compliance, 94 completed the study; 49 in folic acid group and 45 in placebo group. Recurrence of adenomas at 3-year was compared between the two groups. The mean number of recurrent polyps at 3-year was 0.36 (SD, 0.69) for folic acid treated patients compared to 0.82 (SD, 1.17) for placebo treated subjects, resulting in a 3-fold increase in polyp recurrence in the placebo group. Patients below 70 years of age and those with left-sided colonicadenomas or advanced adenomas responded better to folic acid supplementation. CONCLUSION: High dose folic acid supplementation is associated with a signif icant reduction in the recurrence of colonic adenomas suggesting that folic acid may be an effective chemopreventive agent for colorectal neoplasia. | Richard Jaszewski Sabeena Misra Martin Tobi Nadeem Ullah Jo Ann Naumoff Omer Kucuk Edi Levi Bradley N Axelrod Bhaumik B Patel Adhip PN Majumdar | 2008 | World Journal of Gastroenterology2008，14，28： | 10 |
| 2 | Pepsin,a reliable marker of gastric aspiration,is frequently detected in tracheal aspirates from premature ventilated neonates:relationship with feeding and methylxanthine therapy显示文摘 | Sabeena F Zubair HA Tarek N | 2006 | Jounral of Pediatric Gastroen- terology and Nutrition2006，43，3： | 1 |
| 3 | Antioxidant activity of Cod ( Gadus morhua ) protein hydrolysates: Part 1 – In vitro assays and evaluation in 5% fish oil-in-water emulsion显示文摘 | K.H. Sabeena Farvin Lisa Lystb?k Andersen Henrik Hauch Nielsen Charlotte Jacobsen Greta Jakobsen Inez Johansson Flemming Jessen | 2013 | Food Chemistry2013，，： | 1 |
| 4 | Antioxidant activity of yoghurt peptides: Part 2-characterisation of peptide fractions显示文摘 | SABEENA FARVIN K H BARON C P NIELSEN N S | 2010 | Food Chemistry2010，123，4： | 1 |
| 5 | Diagnosis of enteric fever in the emergency department: a retrospective study from Pakistan显示文摘 | Uzma Rahim Khan Junaid A. Razzak Ali Faisal Saleem Adnan Ahmed Sabeena Jalal | 2010 | International Journal of Emergency Medicine2010，，1： | 1 |
| 6 | Antioxidant activity of yoghurt peptides:Part l-in vitro assays and evaluationin x-3 enriched milk显示文摘 | K H Sabeena Farvin Caroline P Baron Nina Skall Nielsen | 2010 | Food Chemistry2010，123，： | 1 |
| 7 | Characterization of a Toxigenie Vibrio cholerae O139 Strain belonging to a new ribotype and isolated from a diarrheal patient显示文摘 | Bhanumathi R Sabeena F Isae SR | 2002 | J Clin Microbiol2002，40，12： | 1 |
| 8 | Potato peel extract as a natural antioxidant in chilled storage of minced horse mackerel(Trachurus trachurus):Effect on lipid and protein oxidation显示文摘 | Sabeena Farvin K H Grejsen H D Jacobsen C | 2012 | Food Chemistry2012，131，3： | 1 |
| 9 | Effect of squa- lene on tissue defense system in isoproterenol-induced myocardial infarction in rats显示文摘 | Sabeena Farvin K H Anandan R Kumar S H | 2004 | Pharmacol Res2004，50，3： | 1 |
| 10 | Molecular characterization of Vibrio cholerae 0139 bengal isolated from water and the aquatic plant Eichhornia crassipes in the River Ganga, Varanasi,India 显示文摘 | Bhanumathi R Sabeena F Isac S R | 2003 | Applied and Environmental Microbiology2003，69，4： | 1 |
| 11 | Bond stress slip response of bars embedded in hybrid fibre reinforced high performance concrete 显示文摘 | Ganesan N Indira P V Sabeena M V | 2014 | Construction and Building Materials2014，50，： | 1 |
| 12 | Antioxidant Activity of Potato Peel Extracts in a Fish-Rapeseed Oil Mixture and in Oil-in-Water Emulsions显示文摘 | Sabeena Farvin Koduvayur Habeebullah Nina Skall Nielsen Charlotte Jacobsen | 2010 | Journal of the American Oil Chemists’ Society2010，，11： | 1 |
| 13 | Potato peel extract as a natural antioxidant in chilled storage of minced horse mackerel (Trachurus trachurus): Effect on lipid and protein oxidation显示文摘 | Sabeena Farvin K H Grejsen H D Jacobsen C | 2012 | Food Chemistry2012，131，3： | 1 |
| 14 | Antioxidant activity of yoghurt peptides:Part 1-in vitro assays and evaluationin x-3 enriched milk显示文摘 | Sabeena Farvin K H Baron Caroline P Nina Skall Nielsen | 2010 | Food Chemistry2010，123，2010： | 1 |
| 15 | Antioxidant activity of yoghurt peptides:Part 1-in vitro assays and evaluationin x-3 enriched milk显示文摘 | K H Sabeena Farvin Caroline P Baron Nina Skall Nielsen | | 0，，： | 1 |
| 16 | Antioxidant activities and functional properties of pro- tein and peptide fractions isolated from salted herring brine 显示文摘 | TAHERI A SABEENA FARVIN K H JACOBSEN C | 2014 | Food Chemistry2014，142，： | 1 |
| 17 | Pepsin,a reliable marker of gastric aspiration, is frequently detected in tracheal aspirates from premature ventilated neonates: relationship with feeding and methylxanthine therapy显示文摘 | Sabeena F Zubair HA Tarek N | 2006 | Jounral of Pediatric Gastroen- terology and Nutrition2006，43，3： | 1 |
| 18 | Characterization of a Toxigenic Vibrio cholerae O139 Strains Belonging to a New Ribotype and Isolated from a Diarrheal Patient显示文摘 | Bhanumathi R Sabeena F SR | 2002 | J Clin Microbiol2002，40，12： | 1 |
| 19 | Molecular characterization of Vibrio cholerae O139 bengal isolated from water and the aquatic plant Eichhornia crassipes in the River Ganga,Varanasi,India显示文摘 | Bhanumathi R Sabeena F Isac SR | 2003 | Appl Environ Microbiol2003，69，4： | 1 |
| 20 | Antioxidant activity of yoghurt peptides: Part 1- in vitro assays and evaluation in ω-3 enriched milk显示文摘 | K.H. Sabeena Farvin Caroline P. Baron Nina Skall Nielsen Charlotte Jacobsen | 2010 | Food Chemistry2010，，4： | 1 |
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