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| 1 | Studies on the overexpression of the soybean GmNHX1 in Lotus corniculatus: The reduced Na^+ level is the basis of the increased salt tolerance显示文摘The full length cDNA coding for a novel vacuolar Na+/H+ antiporter (GmNHX1) was cloned from soybean and determined to consist of 2591 bp with a 5′-untranslated region of 464 bp, an open reading frame (ORF) of 1641 bp, and a 3′-untrans- lated region of 486 bp. The deduced protein se- quence contains 546 aa with the typical characters of the vacuolar Na+/H+ antiporters, and shares high similarity with that of AtNHX1, OsNHX1 and AgNHX1. The soybean genome showed a single copy of the GmNHX1 gene. Northern blot analysis demonstrated that the expression of the GmNHX1 was tissue-spe- cific, increased by ABA treatment, NaCl, KCl, LiCl and dehydration stress, and lower in leaves but higher in roots and hypocotyls of salt-tolerant than salt-sensitive cultivars. The GmNHX1 was overex- pressed under the control of a tandem cauliflower mosaic virus (CaMV) 35S promoter in the model le- guminous plant Lotus corniculatus L. and conferred salt-tolerance of the transgenic plants. Measure- ments of Na+ and K+ contents in both roots and shoots demonstrated that the plantlets of GmNHX1- overexpressing lines had lower Na+ and K+ content, and higher K+/Na+ ratio than the controlled lines that were transformed with the empty vector, which indi- cates that the salt-tolerance conferred by GmNHX1 is closely related with decreased accumulation of Na+ in the transgenic plants. | SUN Yanxiang WANG Dan BAI Yanling WANG Ningning WANG Yong | 2006 | Chinese Science Bulletin2006，51，11： | 10 |
| 2 | Current status of applying microwave-associated catalysis for the degradation of organics in aqueous phase – A review显示文摘Interactions between microwaves and certain catalysts can lead to efficient, energy-directed convergence of a relatively dispersed microwave field onto the reactive sites of the catalyst,which produces thermal or discharge effects around the catalyst. These interactions form'high-energy sites'(HeS) that promote energy efficient utilization and enhanced in situ degradation of organic pollutants. This article focuses on the processes occurring between microwaves and absorbing catalysts, and presents a critical review of microwave-absorbing mechanisms. This article also discusses aqueous phase applications of relevant catalysts(ironbased, carbon-based, soft magnetic, rare earth, and other types) and microwaves, special effects caused by the dimensions and structures of catalytic materials, and the optimization and design of relevant reactors for microwave-assisted catalysis of wastewater. The results of this study demonstrate that microwave-assisted catalysis can effectively enhance the degradation rate of organic compounds in an aqueous phase and has potential applications to a variety of engineering fields such as microwave-assisted pyrolysis, pollutant removal,material synthesis, and water treatment. | Chao Xue Yanpeng Mao Wenlong Wang Zhanlong Song Xiqiang Zhao Jing Sun Yanxiang Wang | 2019 | Journal of Environmental Sciences2019，31，7： | 8 |
| 3 | Characterization and complete genome sequence of vB_EcoP-Bp4,a novel polyvalent N4-like bacteriophage that infects chicken pathogenic Escherichia coli显示文摘Dear Editor,Pathogenic Escherichia coli cause chicken colibacillosis,which is economically devastating to the poultry industry worldwide(Bagheri et al.,2014).Owing to increasing antibiotic resistance,phage therapy reagents have been developed to treat bacterial infections(Xu et al.,2015).Coliphage N4 is the first reported phage in the'N4-like viruses'genus and the only member recognized | Can Zhang Yanxiang Ma Ting Wang Huzhi Sun Guomin Lu Huiying Ren | 2016 | Virologica Sinica2016，31，4： | 7 |
| 4 | Agonistic AT_1 Receptor Autoantibody Increases in Serum of Patients with Refractory Hypertension and Improves Ca^(2+) Mobilization in Cultured Rat Vascular Smooth Muscle Cells显示文摘Agonistic AT1 receptor autoantibodies (AT1-AAs) have been described in the patients with malignant hypertension or preeclampia. Furthermore, AT1-AAs were highly associated with refractory hypertension. Function of vascular smooth muscle cells (VSMCs) is important in the regulation of blood pressure. We investigated and compared the ability of angiotensin II (Ang II) and AT1-AAs to stimulate the intracellular calcium mobilization and cellular proliferation of rat VSMCs. Twenty-two patients with refractory hypertension, 24 patients with non-refractory hypertension and 37 normotensives were recruited. The serum of each patient was detected for the presence of AT1-AAs by ELISA. Ang II and the AT1-AAs from the sera of patients were used to stimulate rat VSMCs in vitro. AT1-AAs were detected in 10/22, 3/24 and 3/37 of patients with refractory hypertension, non-refractory hypertension and normotensives, respectively. AT1-AAs led the increase intracellular calcium mobilization in a dose-dependent manner and cellular proliferation of VSMCs just as Ang II. Both of these effects caused by AT1-AAs were blocked with losartan or a peptide corresponding to a part of the second extracellular loop of AT1 receptor. Since AT1-AAs exhibited pharmacological activity in rat VSMCs just as Ang II, they might play a role in the elevation of peripheral vascular resistance and in vascular remodeling. And AT1-AAs were suggested to involve in resistance to antihypertensive therapy. | Feng Zhu Yanxiang Sun Yuhua Liao Yumiao Wei Ming Chen Min Wang Zihua Zhou | 2008 | Cellular & Molecular Immunology2008，5，3： | 4 |
| 5 | Scaling effects on combustion modes in a single-side expansion kerosene-fueled scramjet combustor显示文摘The combustion modes in two different scramjet combustors with the mass flow rates of 1.8 kg/s and 3.6 kg/s are experimentally investigated to explore the scaling effects on supersonic combustion with a Mach number 2.0 inflow.It is found that the scramjet combustor with a larger scale can broaden the flame rich blowout limit.As the Equivalence Ratio(ER)increases,the combustion in the small-scale combustor maintains in the cavity-stabilized mode,and the flamebase moves downstream along the cavity shear layer;however,the combustion in the large-scale combustor gradually transfers from the cavity-stabilized mode to the jet-wake-stabilized mode.The differences in the cavity residence time,the ignition delay time and the Damkohler number caused by different scales of the scramjet combustor are likely to account for the scaling effects on the combustion modes. | Fan LI Mingbo SUN Jiajian ZHU Zun CAI Hongbo WANG Yanxiang ZHANG Yongchao SUN | 2021 | Chinese Journal of Aeronautics2021，34，5： | 2 |
| 6 | A CTAPras- sisted hydrothermal and solvothermal synthesis of ZnO na- nopowders显示文摘 | Wang Yanxiang Sun Jian Fan Xueyun | 2011 | Ceram Int2011，37，8： | 1 |
| 7 | The differences of osmotic behaviors of bovine embryos from in vitro and in vivo and their quality evaluation显示文摘 | Jiang Guocheng Sun Yanxiang Yang Zhonghua | 1997 | Theriogenology1997，47，1： | 1 |
| 8 | A Model of Distributed OS Automatic Generating System显示文摘Nowadays,there are some problems in the area of distributed operating system(DOS)and its research methods.To solve these problems,we have provided a Distributed Operat-ing System Auto-generating System(DOSAGS)model,which is characterized by intelli-gence,integration and moldability.DOSAGS’ system structure,functions,work principlesand key problems in its implementation are presented.It is obvious that the DOS generatedby DOSAGS is a real new generation distributed OS. | He Yanxiang Xia Xunbin Chen Yantao Sun Xiangsheng (Department of Computer Science,Wuhan University Wuhan 430072,P.R.China) | 1995 | High Technology Letters1995，1，1： | 1 |
| 9 | The differences of osmotic behaviors of bovine embryos from invitro and in vivo and their quality evaluation显示文摘 | Jiang Guocheng Sun Yanxiang Yang Zhonghua | 1997 | Theriogenology1997，47，1： | 1 |
| 10 | Identification and evaluation of modification level for compacted graphite cast iron 显示文摘 | Sun Xinjian Li Yanxiang Chen Xiang | 2008 | Journal of Materials Processing Technology2008，200，13： | 1 |
| 11 | Controlling melt quality of compacted graphite iron 显示文摘 | Sun Xinjian Li Yanxiang Chen Xiang | 2007 | Materials Science and Engineering A2007，466，12： | 1 |
| 12 | Free and esterified triterpene alcohol composition of bee pollen from different botanical origins显示文摘 | XU Xiang GAO Yanxiang SUN Liping | 2012 | Food Research International2012，48，： | 1 |
| 13 | Tanshinone IA decreases microcalcifications in plaque via Nox1-dependent reactive oxygen species generation of smooth muscle cells in apoE^(-/-) mice显示文摘A variety of NADPH oxidase(Nox)isoforms including Noxs 1,2,4 and 5 catalyze the formation of reactive oxygen species(ROS)in the vascular wall.The Noxl isoform complex in smooth muscle cells has received greater attention in the progression of atherogenesis in animal models.Thus,we explored the effect of traditional Chinese herbal medicine monomer tanshinone IIA on microcalcifications,and investigated the underlying molecular mechanism of ROS.The 8-week old maleapolipoprotein E-deficient(ApoE^(-/-))mice and C57BL/6 mice were divided into three groups:Control group(C57BL/6 mice),Model group(ApoE^(-/-) mice). | Sun Weiliang Guo Jing Zhang Yuting Gao Yanxiang | 2021 | 解剖学杂志2021，44，S01： | 0 |
| 14 | Ticagrelor versus clopidogrel in East Asian patients with acute coronary syndrome:A meta-analysis显示文摘Objective:There exist conflicting data on the efficacy and safety of ticagrelor and clopidogrel in East Asian patients with acute coronary syndrome(ACS).We performed a meta-analysis to evaluate whether ticagrelor or clopidogrel produces better outcomes for East Asian patients with ACS.Methods:We searched for randomized controlled trials reporting associations between ticagrelor and clopidogrel in East Asian patients with acute coronary syndrome in PubMed,EMBASE,web of science and Cochrane central register of controlled trials.Results:Ten studies involving 3715 participants were qualified for our analysis.The major adverse cardiovascular events(MACE)were significantly decreased in patients with ticagrelor treatment compared to those with clopidogrel(risk ratio[RR]:0.61;95%confidence interval[CI]:0.38-0.98;P=0.042).There was no significant difference in all-cause death(RR:0.89;95%CI:0.61-1.29;P=0.540),cardiovascular death(RR:0.86;95%CI:0.58-1.27;P=0.451),myocardial infarction(RR:0.91;95%CI:0.65-1.27;P=0.575)and stroke(RR:0.77;95%CI:0.44-1.36;P=0.372)between ticagrelor and clopidogrel.Ticagrelor was associated with a significantly higher risk of bleeding compared to clopidogrel(RR:1.71;95%CI:1.37-2.13;P=0.000).Conclusion:The present meta-analysis demonstrates that ticagrelor reduced the incidence of MACE in ACS patients from East Asia compared with clopidogrel.However,it increased the risk of bleeding. | Meijiao He Yanxiang Zang Danghui Sun Jianqiang Li Guangzhong Liu Jing Shi Yue Li | 2022 | Frigid Zone Medicine2022，2，1： | 0 |
| 15 | Roles of UV light strength and auxiliary electric field in the photocatalytic degradation effect of organic contaminant显示文摘The accumulation of contaminants on the electrical devices could adversely affect the operation.The present work used photocatalytic functional material to coat on the surface of the electrical devices to prevent the influence of organic contamination.This kind of material was mainly composed of TiO_(2)that can remove the contamination by the effect of photooxidation.The photocatalysis was affected by the strength of UV light and electric field.In the experiment,methyl orange(MO)was used as the organic contaminant.The effect of UV light and auxiliary electric field were analysed based on the theoretical simulation.With the stronger UV light,more electron-hole pairs were generated,photocatalytic effect became more pronounced.With the auxiliary electric field,the recombination of electron and hole could be restrained that would increase the productive rate of hole;therefore,more hydroxyl radical will be produced to degrade MO. | Lin YaoYu Ma YanXiang Bian XingMing Sun PengCheng | 2019 | High Voltage2019，4，2： | 0 |
| 16 | Hepatitis B Virus Induces Microtubule Stabilization to Promote Productive Infection through Upregulating Microtubule-associated Protein 1S显示文摘Background and Aims:Continuous release and transmission of hepatitis B virus(HBV)is one of the main factors leading to chronic hepatitis B(CHB)infection.However,the mechanism of HBV-host interaction for optimal viral transport is unclear.Hence,we aimed to explore how HBV manipulates microtubule-associated protein 1S(MAP1S)and microtubule(MT)to facilitate its transport and release.Methods:The expression of MAP1S or acetylated MT was investigated by immunofluorescence,RT-PCR,immunoblotting,and plasmid transfection.MAP1S overexpression or knockdown was performed by lentiviral infection or shRNA transfection,respectively.HBV DNA was quantified using q-PCR.Results:Significantly higher level of MAP1S in HepG2215 cells compared with HepG2 cells was detected using RT-PCR(p<0.01)and immunoblotting(p<0.001).Notably,stronger MAP1S expression was observed in the liver tissues of patients with CHB than in healthy controls.MAP1S overexpression or knockdown demonstrated that MAP1S promoted MT acetylation and reduced the ratio of HBV DNA copies inside to outside cells.Further,transfection with the hepatitis B virus X protein(HBx)-expressing plasmids induced significantly higher level of MAP1S than that in controls(p<0.0001),whereas HBVX−mutant-encoding HBV proteins(surface antigen,core protein,and viral DNA polymerase)hardly affected its expression.Conclusions:These results demonstrate that HBx induces the forma tion of stable MTs to promote the release of HBV particles through upregulating MAP1S.Thus,our studies delineate a unique molecular pathway through which HBV manipulates the cytoskeleton to facilitate its own transportation,and indicate the possibility of targeting MAP1S pathway for treatment of patients with CHB. | Yuanyue Guan Bin Sun Shijie Zhang Yuan Zhuang Yanxiang Huang Minghua Lin Rongling Zheng Dexi Chen Ying Shi Yanjun Wang | 2022 | Journal of Clinical and Translational Hepatology2022，10，3： | 0 |
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