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617篇 您的检索式:作者名="STEWART D A"
    题名 作者 年代 出处 被引量
1Dynamic chromatin states in human ES cells reveal potential regulatory sequences and genes involved in pluripotency显示文摘Pluripotency,一个细胞的能力区分并且产生所有胚胎的系,定义象胚胎的茎(ES ) 那样的哺乳动物的细胞类型的一个小数字细胞。当它通常被保持了时,那 pluripotency 是 transcriptional 的产品激活并且维持关键干细胞基因的表达式的规章的网络,积累的证据在建立并且保卫 ES 房间的 pluripotency 为 epigenetic 进程正在指向一个关键角色,象维持区分的房间类型的身份一样。以便更好在 pluripotency 理解 epigenetic 机制的角色,我们检验了在经历区别进一个 mesendodermal 系的人的 ES 房间(hESCs ) 染色体宽的染色质修正的动力学。我们发现在倡导者的染色质修正在区别期间仍然保持大部分不变,除了在在在 H3K27 的 acetylation 和 methylation 之间的一个动态开关标记在基因表示的激活和 silencing 之间的转变的倡导者的一个小数字,建议在在大多数差别上的房间命运承诺的一个层次表示了基因。我们也在 50 000 潜在的 enhancers 上印射,并且在染色质修正,特别 H3K4me1 和 H3K27ac 观察了大得多的动力学,它与他们的潜在的目标基因的表示相关。这些 enhancers 的进一步的分析揭示了 pluripotency 和可以在 hESCs 授与发展胜任的一个平衡状态的一口染色质签名陈述语气的潜在地关键的 transcriptional 管理者。我们的结果提供在定义 enhancers 和 pluripotency 支持染色质修正的角色的新证据。R David Hawkins Gary C Hon Chuhu Yang Jessica E Antosiewicz-Bourget Leonard K Lee Que-Minh Ngo Sarit Klugman Keith A Ching Lee E Edsall Zhen Ye Samantha Kuan Pengzhi Yu Hui Liu Xinmin Zhang Roland D Green Victor V Lobanenkov Ron Stewart James A Thomson Bing Ren 2011Cell Research2011,21,10:6
2子宫炎性肌纤维母细胞肿瘤通常存在ALK与IGFBP5和THBS1基因的融合显示文摘炎性肌纤维母细胞肿瘤能够发生在包括子宫在内的多个解剖部位。子宫炎性肌纤维母细胞肿瘤与发生在软组织的炎性肌纤维母细胞肿瘤相似,也通常表达ALK,并存在ALK基因重排。该文着重分析子宫炎性肌纤维母细胞肿瘤的基因融合特征。Haimes J D Stewart C J R Kudlow B A 赵芳 魏建国 2018临床与实验病理学杂志2018,34,1:2
3Prohibitin an evalutionarily conserved intracellular protein that blocks DNA synthesis in normal fthroblasts and HeLa cells 显示文摘Nuell M J Stewart D A Walker L 1991Mal Cell Biol1991,11,3:1
4A contingency perspective on organizational learning: integrating environment context, organizational learning processes and types of learning 显示文摘GNYAWALI D R STEWART A C 2003Management learning2003,34,1:1
5Root proliferation, soil fauna and plant nitrogen capture from nutrient-rich patches in soil 显示文摘Hodge A Stewart J Robinson D 1998New Phytologist1998,139,3:1
6Effect of volatiles from bacteria and yeast on the growth and pigmentation of sapstain fungi显示文摘Brace A Stewart D Verrall S 2003International Biodeterioration & Biodeg''radation2003,51,2:1
7A gene map of the human genome显示文摘Schuler G D Boguski M S Stewart E A 1996Science1996,274,:1
8Abrasive wear behaviour of conventional and nanocomposite HVOF-sprayed WC-Co coatings显示文摘STEWART D A SHIPWAY P H MCCARTN E Y D G 1999Wear1999,225,2:1
9Asymmetrie bioreductions of 13-ni- troacrylates as a route to chiral 13 2-amino acids显示文摘Swiderska M A Stewart J D 2006Organic Letter2006,8,26:1
10Biofilm resistance to antimicrobial agents显示文摘XU K D McFETERS G A STEWART P S 2000Microbiology2000,146,3:1
11Isolation of a cDNA that hybrid selects antiproliferative mRNA from rat liver显示文摘McClung J K Danner D B Stewart D A 1989Biochem Biophys1989,16,4:1
12Influence of plant density on cot ton response to mepiquat chloride application显示文摘SIEBERT J D Stewart A M 2006Agronomy Journal2006,98,:1
13An improved in vivo method for atrioventricu lar node ablation via thoracotomy显示文摘Maciver R H Stewart R D Backer C L Tsao S Harrington D A Mavroudis C 2010Braz J Med Biol Res2010,43,:1
14Reactive processin-gof poly(ethylene 2,6-naphthalate dicarboxylate)/poly(ethylene terephthalate)blends显示文摘Stewart M E Cox A J Naylor D M 0,,19:1
15Microstructural evolution in thermally sprayed WC-Co coatings: Comparison between nanocomposite and conventional starting powders 显示文摘Stewart D A Shipway P H McCartney D G 2000Acta Materialia2000,48,7:1
16Antiproliferative activity is predominantly associated with ellagitannins in raspberry extracts 显示文摘Ross H A McDougall J Stewart D 2007Phytochemistry2007,68,:1
17Determination of iron in semiconductor-grade silicon by furnace atomic-absorption spectrometry显示文摘STEWART D A NEWTON D C 1983Analyst1983,108,1293:1
18Comparative growth and yield of cotton grown in various densities and configura- tions 显示文摘SEIBERT J D STEWART A M LEONARD B R 2006Agron J2006,98,:1
19A review of recent studies on malondialdehyde as toxic molecule and biological marker of oxidative stress 显示文摘Del Rio D Stewart A J Pellegrini N 2005Nutr Metab Cardiovasc Dis2005,15,4:1
20Defects in cutaneous angiotensin converting enzyme 2 and angiotensin - ( 1 - 7 ) production in postural tachycardia syndrome 显示文摘Stewart JM Ocon A J Clarke D 2009Hypertension2009,53,5:1
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