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560篇 您的检索式:作者名="STEWART A C"
    题名 作者 年代 出处 被引量
1Dynamic chromatin states in human ES cells reveal potential regulatory sequences and genes involved in pluripotency显示文摘Pluripotency,一个细胞的能力区分并且产生所有胚胎的系,定义象胚胎的茎(ES ) 那样的哺乳动物的细胞类型的一个小数字细胞。当它通常被保持了时,那 pluripotency 是 transcriptional 的产品激活并且维持关键干细胞基因的表达式的规章的网络,积累的证据在建立并且保卫 ES 房间的 pluripotency 为 epigenetic 进程正在指向一个关键角色,象维持区分的房间类型的身份一样。以便更好在 pluripotency 理解 epigenetic 机制的角色,我们检验了在经历区别进一个 mesendodermal 系的人的 ES 房间(hESCs ) 染色体宽的染色质修正的动力学。我们发现在倡导者的染色质修正在区别期间仍然保持大部分不变,除了在在在 H3K27 的 acetylation 和 methylation 之间的一个动态开关标记在基因表示的激活和 silencing 之间的转变的倡导者的一个小数字,建议在在大多数差别上的房间命运承诺的一个层次表示了基因。我们也在 50 000 潜在的 enhancers 上印射,并且在染色质修正,特别 H3K4me1 和 H3K27ac 观察了大得多的动力学,它与他们的潜在的目标基因的表示相关。这些 enhancers 的进一步的分析揭示了 pluripotency 和可以在 hESCs 授与发展胜任的一个平衡状态的一口染色质签名陈述语气的潜在地关键的 transcriptional 管理者。我们的结果提供在定义 enhancers 和 pluripotency 支持染色质修正的角色的新证据。R David Hawkins Gary C Hon Chuhu Yang Jessica E Antosiewicz-Bourget Leonard K Lee Que-Minh Ngo Sarit Klugman Keith A Ching Lee E Edsall Zhen Ye Samantha Kuan Pengzhi Yu Hui Liu Xinmin Zhang Roland D Green Victor V Lobanenkov Ron Stewart James A Thomson Bing Ren 2011Cell Research2011,21,10:6
2子宫炎性肌纤维母细胞肿瘤通常存在ALK与IGFBP5和THBS1基因的融合显示文摘炎性肌纤维母细胞肿瘤能够发生在包括子宫在内的多个解剖部位。子宫炎性肌纤维母细胞肿瘤与发生在软组织的炎性肌纤维母细胞肿瘤相似,也通常表达ALK,并存在ALK基因重排。该文着重分析子宫炎性肌纤维母细胞肿瘤的基因融合特征。Haimes J D Stewart C J R Kudlow B A 赵芳 魏建国 2018临床与实验病理学杂志2018,34,1:2
3Extensive butyltin contamination in southwestern coastal British Columbia显示文摘Stewart C Thompson J A J 1994Marine Pollution Bulletin1994,28,:1
4Multi-destination trip patterns显示文摘Stewart S I Vogt C A 1997Annals of Tourism Research1997,24,2:1
5A contingency perspective on organizational learning: integrating environment context, organizational learning processes and types of learning 显示文摘GNYAWALI D R STEWART A C 2003Management learning2003,34,1:1
6Bacteria-induced de-emulsification of oil-in-water petroleum emulsions 显示文摘Gray N C C Stewart A L Cairns W L 1984Biotechnology Letters1984,6,7:1
7Influence of nitrogen source and availability on amino acids pigments and tissue nitrogen of Gracilaria eduils (Rhodophyta) 显示文摘 Dennison W C Stewart G R 1996J Phycol1996,32,:1
8Studies on the decontamination of air by Chilean plants显示文摘Cornejo J J Munoz F G Ma C Y Stewart A J 1999Ecotoxicology1999,8,:1
9Substrate-induced phenotypic switches of human smooth muscle cells: an in vitro study of in-stent restenosis activation pathways显示文摘GUILDFORD A L STEWART H J MORRIS C 2011J R Soc Interface2011,8,58:1
10Immune reactive cells in senile plaques and cognitive decline in Alzheimer's disease显示文摘Vehamas A Kawas C Stewart W 2003Neurobiol Aging2003,24,2:1
11Loss of myosin Ⅵ reduces secretion and the size of the Golgi in fibroblasts from Snell' s waltzer mice显示文摘WARNER C L STEWART A LUZIO J P 2003EMBO J2003,22,3:1
12An improved in vivo method for atrioventricu lar node ablation via thoracotomy显示文摘Maciver R H Stewart R D Backer C L Tsao S Harrington D A Mavroudis C 2010Braz J Med Biol Res2010,43,:1
13Field and laboratory studies of Desmodora cazca Gerlach,1956 (Desmodoridae:Nematoda) from mangrove mud-flats显示文摘Nicholas W L Stewart A C Marples T G 1988Nematologica1988,34,3:1
14Natural infection of pigs with bovine viral diarrhea virus and its differential diagnosis from hog cholera 显示文摘Carbrey E A Stewart W C Kresse J I 1976J Am Vet Med Assoc1976,169,:1
15Growth of alligator weed (A lternanthera philoxeroides)and population development of Agasicles hygrophila in northern New Zealand显示文摘Stewart C A Chapman R B Frampton C M A 2000Plant Protection Quarterly2000,15,1:1
16Natural infection of pigs with bovine viral diarrhea virus and its differential diagnosis from hog cholera显示文摘Carbrey'E A Stewart W C Kresse J I 1976J Arn Vet Med Assoc1976,169,11:1
17Determination of iron in semiconductor-grade silicon by furnace atomic-absorption spectrometry显示文摘STEWART D A NEWTON D C 1983Analyst1983,108,1293:1
18Abnormal loading of the major joints in knee osteoarthritis and the response to knee replacement显示文摘Metealfe A Stewart C Postans N 2013Gait Posture2013,37,1:1
19Tissue - specific expression of male-transmitted mitochondrial DNA and its implications for rates of molecular evolution in Mytilus mussels ( Bivalvia: Mytilidae) 显示文摘DALZIEL A C STEWART D T 2002Genome2002,45,2:1
20Different and divergent regulation of the KIR2DL4 and KIR3DL4 promoters显示文摘Stewart C A van Bergen J Trowsdale J 2003J Immunol2003,170,12:1
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