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| 1 | Survival benefit in patients after palliative resection vs non-resection colon cancer surgery显示文摘AIM: To evaluate survival in patients undergoing pallia- tive resection versus non-resection surgery for primary colorectal cancer in a retrospective analysis. METHODS: Demographics, TNM status, operating de- tails and survival were reviewed for 67 patients under- going surgery for incurable colorectal cancer. Palliative resection of the primary tumor was performed in 46 cases in contrast to 21 patients with non-resection of the primary tumor and bypass surgery. Risk factors for post- operative mortality and poor survival were analyzed with univariate and multivariate analyses.RESULTS: The two groups were comparable in terms of age, gender, preoperative presence of ileus and tumor stage. Multivariate analysis showed that median survival was significantly higher in patients with palliative resec- tion surgery (544 vs 233 d). Differentiation of the tumor and tumor size were additional independent factors that were associated with a significantly poorer survival rate. CONCLUSION: Palliative resection surgery for primary colorectal cancer is associated with a higher median survival rate. Also, the presence of liver metastasis and tumor size are associated with poor survival. Therefore, resection of the primary tumor should be considered in patients with non-curable colon cancer. | A Beham M Rentsch K Püllmann L Mantouvalou H Spatz HJ Schlitt A Obed | 2006 | World Journal of Gastroenterology2006，12，41： | 5 |
| 2 | Preparation of stable micropatterns of gold on cell-adhesion-resistant hydrogels assisted by a hetero-bifunctional macromonomer linker显示文摘Surface patterning is very useful in biomaterial studies, yet it is not easy to prepare a micropattern with cell-adhesion contrast that is stable in a wet environment. Recently, a platform technique of transfer photolithography was invented to fabricate stable metal microarrays on the surface of a cell-adhesion resistant and mechanically biomimetic poly(ethylene glycol) hydrogel; the linker is the key chemical in such a transfer strategy. This article reports the design and synthesis of a hetero-bifunctional macromonomer linker with a thiol group at one end and an acryloyl group at the other end. The bifunctional linker was characterized by GPC and 1H NMR, and the average number of thiol groups in the bifunctional linker was detected by Ellman's reagent. The regent stability under wet conditions was also confirmed by the model reactants. The resultant micropatterned surfaces are meaningful for future studies of cell behaviors on mechanically biomimetic matrixes. | SUN JianGuo GRAETER Stefan V TANG Jian HUANG JingHuan LIU Peng LAI YuXiao YU Lin MAJER Günter SPATZ Joachim P DING JianDong | 2014 | Science China Chemistry2014，57，4： | 2 |
| 3 | Connections between single-cell biomechanics and human disease states: gastrointestinal cancer and malaria显示文摘 | Suresh S Spatz J Mills J P | 2005 | Acta Biomater2005，，1： | 1 |
| 4 | Supplementary material S5: computational modeling of optical tweezers stretching of malaria-infected human red blood cells显示文摘 | Suresh S Spatz J Mills J P | 2005 | Acta Biomater2005，，1： | 1 |
| 5 | Mechanically milled Mg composites for hydrogen storage the transition to a steady state composition显示文摘 | SPATZ P Z(U)TTEL A | 1996 | J Alloys and Compounds1996，240，12： | 1 |
| 6 | Noble metal loaded block ionomers : micelle organization, adsorption of free chains and formation of thin films 显示文摘 | Spatz J P Roescher A Sheiko S | 1995 | Ady Mater1995，，7： | 1 |
| 7 | Environmental sensing through focal adhesions 显示文摘 | Geiger B Spatz J P Bershadsky A D | 2009 | Nat Rev Mol Cell Biol2009，10，1： | 1 |
| 8 | Block copolymer micelle nanolithography 显示文摘 | Glass R Moeller M Spatz J P | 2003 | Nanotechnology2003，14，10： | 1 |
| 9 | Ordered deposition of inorganic clusters from micellar block copolymer films 显示文摘 | Spatz J P Mossmer S Hartmann C | 2000 | Langmuir2000，16，2： | 1 |
| 10 | Mechanically milled Mg composites for hydrogen storage-the transition to a steady state composition显示文摘 | GROSS K J SPATZ P ZUTTEL A | 1996 | Journal of Alloy and Componnds1996，240，： | 1 |
| 11 | Towards a“free radical theory of graying”:Melanocyte apoptosis in the aging human hair follicle is an indicator of oxidative stress induced tissue damage显示文摘 | ARCK P C OVERALL R SPATZ K | 2006 | The FASEB Journal2006，20，9： | 1 |
| 12 | Primary yolk sac tumor of the endometrium : a case report and review of the literature 显示文摘 | Spatz A Bouron D Pautier P | 1998 | Gynecol Oncol1998，70，2： | 1 |
| 13 | Tailored antireflective biomimetic nanostructures for UV applications显示文摘 | Christoph Morhard Claudia Pacholski Dennis Lehr Robert Brunner Michael Helgert Michael Sundermann Joachim P Spatz | 2010 | Nanotechnology2010，，42： | 1 |
| 14 | Observation of Crossover from Three- to Two-dimensional Variable-range Hopping in Template-synthesized Polypyrrole and Polyaniline 显示文摘 | SPATZ J P LORENZ B WEISHAUPT K | 1994 | Phys Rev B1994，50，14： | 1 |
| 15 | 显示文摘 | Gross K J Spatz P Zuettel A Schoapbach L | 1996 | J Alloys Compd1996，240，： | 1 |
| 16 | Gold - polypyrrole core - shell particles in diblock copolymer micelles 显示文摘 | Selvan T Spatz J P Klok H A | 1998 | Ad- vanced Materials1998，10，2： | 1 |
| 17 | Micellar inorganic-polymer hybrid systems-a tool for nanolithography显示文摘 | Herzog T Mobmer S | 1999 | Adv Mater1999，11，： | 1 |
| 18 | Gold Nanoparticles in Micellar Poly ( styrene ) - b - Poly ( - ethyleneoxide ) Films 显示文摘 | Spatz J P Roesher A Moiler M | 1996 | Adv Mater1996，8，： | 1 |
| 19 | Treating depression in patients with Academic heart disease显示文摘 | Steven P Roose Erica Spatz | 2000 | Practi Dru Safe2000，21，5： | 1 |
| 20 | Mechanicallymilled Mg composites for hydrogen storage:the transitionto a steady state composition显示文摘 | GROSS K J SPATZ P ZUTTEL A | 1996 | J Alloys Compd1996，240，： | 1 |
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