|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Helicobacter pylori in human health and disease:Mechanisms for local gastric and systemic effects显示文摘Helicobacter pylori(H. pylori) is present in roughly 50% of the human population worldwide and infection levels reach over 70% in developing countries. The infection has classically been associated with different gastro-intestinal diseases, but also with extra gastric diseases. Despite such associations, the bacterium frequently persists in the human host without inducing disease, and it has been suggested that H. pylori may also play a beneficial role in health. To understand how H. pylori can produce such diverse effects in the human host, several studies have focused on understanding the local and systemic effects triggered by this bacterium. One of the main mechanisms by which H. pylori is thought to damage the host is by inducing local and systemic inflammation. However, more recently, studies are beginning to focus on the effects of H. pylori and its metabolism on the gastric and intestinal microbiome. The objective of this review is to discuss how H. pylori has co-evolved with humans, how H. pylori presence is associated with positive and negative effects in human health and how inflammation and/or changes in the microbiome are associated with the observed outcomes. | Denisse Bravo Anilei Hoare Cristopher Soto Manuel A Valenzuela Andrew FG Quest | 2018 | World Journal of Gastroenterology2018，24，28： | 32 |
| 2 | Going beyond 1000000 resolved points in a Brillouin distributed fiber sensor: theoretical analysis and experimental demonstration显示文摘Distributed fiber sensing possesses the unique ability to measure the distributed profile of an environmental quantity along many tens of kilometers with spatial resolutions in the meter or even centimeter scale.This feature enables distributed sensors to provide a large number of resolved points using a single optical fiber.However,in current systems,this number has remained constrained to a few hundreds of thousands due to the finite signal-to-noise ratio(SNR)of the measurements,which imposes significant challenges in the development of more performing sensors.Here,we propose and experimentally demonstrate an ultimately optimized distributed fiber sensor capable of resolving 2100000 independent points,which corresponds to a one-orderof-magnitude improvement compared to the state-of-the-art.Using a Brillouin distributed fiber sensor based on phase-modulation correlation-domain analysis combined with temporal gating of the pump and time-domain acquisition,a spatial resolution of 8.3 mm is demonstrated over a distance of 17.5 km.The sensor design addresses the most relevant factors impacting the SNR and the performance of medium-to-long range sensors as well as of sub-meter spatial resolution schemes.This step record in the number of resolved points could be reached due to two theoretical models proposed and experimentally validated in this study:one model describes the spatial resolution of the system and its relation with the sampling interval,and the other describes the amplitude response of the sensor,providing an accurate estimation of the SNR of the measurements. | Andrey Denisov Marcelo A Soto Luc Thévenaz | 2016 | Light(Science & Applications)2016，5，1： | 11 |
| 3 | Influence of dissolved organic matter character on mercury incorporation by planktonic organisms: An experimental study using oligotrophic water from Patagonian lakes显示文摘Ligands present in dissolved organic matter(DOM) form complexes with inorganic divalent mercury(Hg2+) afecting its bioavailability in pelagic food webs. This investigation addresses the influence of a natural gradient of DOM present in Patagonian lakes on the bioaccumulation of Hg2+(the prevailing mercury species in the water column of these lakes) by the algae Cryptomonas erosa and the zooplankters Brachionus calyciflorus and Boeckella antiqua. Hg2+accumulation was studied through laboratory experiments using natural water of four oligotrophic Patagonian lakes amended with197Hg2+. The bioavailability of Hg2+was afected by the concentration and character of DOM. The entrance of Hg2+into pelagic food webs occurs mostly through passive and active accumulation. The incorporation of Hg2+by Cryptomonas, up to 27% of the Hg2+amended, was found to be rapid and dominated by passive adsorption,and was greatest when low molecular weight compounds with protein-like or small phenolic signatures prevailed in the DOM.Conversely, high molecular weight compounds with a humic or fulvic signature kept Hg2+in the dissolved phase, resulting in the lowest Hg2+accumulation in this algae. In Brachionus and Boeckella the direct incorporation of Hg from the aqueous phase was up to3% of the Hg2+amended. The dietary incorporation of Hg2+by Boeckella exceeded the direct absorption of this metal in natural water,and was remarkably similar to the Hg2+adsorbed in their prey. Overall, DOM concentration and character afected the adsorption of Hg2+by algae through competitive binding, while the incorporation of Hg2+into the zooplankton was dominated by trophic or dietary transfer. | María C.Diéguez Claudia P.Queimalios Sergio Ribeiro Guevara Mark Marvin-DiPasquale Carolina Soto Crdenas María A.Arribre | 2013 | Journal of Environmental Sciences2013，25，10： | 6 |
| 4 | An overview of the American trauma system显示文摘美国损伤系统被设计提供组织回答给损害。它从象在城市的社区医院里开发的原则一样在第 20 世纪的战争从美洲参与接受的教训拉它的基础。尽管在本地、州的政府水平跑,它被国家社会指导并且成为了一个世界级例子。它当前也面对 ? 有衰退偿还和提供的平等者的挑战存取喜欢所有美国人。职业社会和立法身体持续为这些问题的公平、公平的答案一起正在工作。 | Jose M. Soto Yilu Zhang Jason H. Huang Dong-Xia Feng | 2018 | Chinese Journal of Traumatology2018，21，2： | 5 |
| 5 | OPTIMIZATION OF A WAVE CANCELLATION MULTIHULL SHIP USING CFD TOOLS显示文摘A simple CFD tool, coupled to a discrete surface representation and a gradient based optimization procedure, is applied to the design of optimal hull forms and optimal arrangement of hulls for a wave cancellation multihull ship. The CFD tool, which is used to estimate the wave drag, is based on the zeroth order slender ship approximation. The hu ll surface is represented by a triangulation, and almost every grid point on the surface can be used as a design variable. A smooth surface is obtained via a si mplified pseudo shell problem. The optimal design process consists of two steps . The optimal center and outer hull forms are determined independently in the fi rst step, where each hull forms are determined independently in the first step, where each hull keeps the same displacement as the original design while the wav e drag is minimized. The optimal outer hull arrangement is determined in the se cond step for the optimal center and outer hull forms obtained in the first step . Results indicate that the new design can achieve a large wave drag reduction i n comparison to the original design configuration. | C. Yang, R. L■hner, O. Soto (School of Computational Sciences, George Mason University Fairfax VA 22030-4444, USA) | 2002 | Journal of Hydrodynamics2002，14，1： | 5 |
| 6 | Diabetic gastroenteropathy:An underdiagnosed complication显示文摘This article is an extensive review that provides an update on the pathophysiology,symptoms,diagnosis,and treatment of diabetic gastroenteropathy.There is no reported prevalence,but it has been described that patients with type 1 diabetes have a cumulative incidence at 10 years of 5.2%,and type 2 patients,1%.Also,in the group of type 1 diabetes,it has been observed that women are more likely to present this condition(5.8%vs 3.5%).Many factors are associate with its development(e.g.,hyperglycemia,vagal dysfunction,loss of expression of neural nitric oxide synthase in the myenteric plexus,alterations in the Cajal interstitial cell network,and oxidative stress).Gastrointestinal discomfort could be perceived 70% higher in diabetic patients,describing that 25%of diabetic patients experience gastrointestinal symptoms.Diabetic enteropathy could affect any portion of the gastrointestinal tract,but esophageal alterations were described in more than 60% of diabetic patients,also 60% of them present constipation,and 20%,diarrhea.Gastric emptying scintigraphy is useful to evaluate gastroparesis,therefore,gastric retention of more than 60%at 2 h has a sensitivity of 100% and specificity of 20% for diagnosis;however,other studies such as breath tests,with a sensitivity of 89% and a specificity of 80%,or the endoscopic capsule contribute to the diagnosis.There is no cure;however,management must be multidisciplinary,focused on slowing the progression of diabetic gastroenteropathy,reducing symptoms,and restoring function;that includes nutritional recommendation,maintain glucose levels kept below 180 mg/dL,use of prokinetics,anti-emetics;nowadays,it has been special interest in surgical treatment,such as pyloroplasty,also gastric electrical stimulation appears to be another alternative. | Marcio JoséConcepción Zavaleta Jhean Gabriel Gonzáles Yovera Diego Martín Moreno Marreros Luciana del Pilar Rafael Robles Kely Roxana Palomino Taype Karen Nohelly Soto Gálvez Luis Fernando Arriola Torres Julia Cristina Coronado Arroyo Luis Alberto Concepción Urteaga | 2021 | World Journal of Diabetes2021，12，6： | 4 |
| 7 | Liquid-liquid interfacial tension of equilibrated mixtures of ionic liquids and hydrocarbons显示文摘Ionic liquids are possible alternative solvents for the separation of aromatic and aliphatic hydrocarbons by liquid-liquid extrac- tion. Interfacial tension is an important property to consider in the design of liquid-liquid extraction processes. In this work, the liquid-liquid interfacial tension and the mutual solubility at 25 °C have been measured for a series of biphasic, equilibrated mixtures of an ionic liquid and a hydrocarbon. In particular, the ionic liquids 1-alkyl-3-methylimidazolium bis(trifluorome- thanesulfonyl)imide (with the alkyl substituent being ethyl, hexyl or decyl), 1-ethyl-3-methylimidazolium ethylsulfate, and 1-ethyl-3-methylimidazolium methanesulfonate have been selected, as well as the hydrocarbons benzene, hexane, ethylben- zene, and octane. The selected sets of ionic liquids and hydrocarbons allow the analysis of the influence of a series of effects on the interfacial tension. For example, the interfacial tension decreases with an increase in the length of the alkyl substituent chain of the cation or with an increase of the degree of charge delocalisation in the anion of the ionic liquid. Also, the interfa- cial tension with the aromatic hydrocarbons is markedly lower than that with the aliphatic hydrocarbons. A smaller effect is caused by variation of the size of the hydrocarbon. Some of the observed trends can be explained from the mutual solubility of the hydrocarbon and the ionic liquid. | RODRíGUEZ Héctor ARCE Alberto SOTO Ana | 2012 | Science China Chemistry2012，55，8： | 4 |
| 8 | Morphological Characterization and Hydrodynamic Behavior of Shortfin Mako Shark(Isurus oxyrinchus)Dorsal Fin Denticles显示文摘The shortfin mako shark(Isurus oxyrinchus)is one of the fastest marine fishes,reaching speeds of up to 70 km·h^-1.Their speed is related to the skin surface design composed of dermal denticles.Denticles vary in size and shape according to placement on the body and minimize turbulence around the body.The objective of this study is to analyze the interaction between seawater flow and denticles on the dorsal fin.High-resolution microscopy(scanning electron microscopy and confocal microscopy)were used to measure defined parts of the dermal denticles.These measurements,along with ratios based on length-to-width define three morphologies(rounded,semi-rounded,long)that were 3D reconstructed.Computational fluid dynamics simulated fluid passage over reconstructed denticles and describe hy-drodynamic efficiency under different conditions.An increase in angle of inclination produced a relevant increase in the drag coefficient,especially for high velocity inlets.The lowest drag coefficient values were found in long and semi-rounded,followed by rounded mor-phologies.The hydrodynamic behavior of shark skin demonstrates a relation to the morphological characteristics of dermal denticles on the dorsal fin.It is concluded that the best hydroefficiency relies on the rounded morphology and may serve to design hydrodynamically efficient surfaces or manmade assemblies. | Fernandez-Waid Patricia Diez Guzman Bidaguren Inigo Izagirre Urtzi Blanco Jesus Maria Soto Manu | 2019 | Journal of Bionic Engineering2019，16，4： | 3 |
| 9 | Smoking and Inflammatory Bowel Disease: A Meta-analysis显示文摘 | Suhal S. Mahid Kyle S. Minor Roberto E. Soto Carlton A. Hornung Susan Galandiuk | 2006 | Mayo Clinic Proceedings2006，，11： | 3 |
| 10 | Comparative study of the efficacy and safety of bromfenac, nepafenac and diclofenac sodium for the prevention of cystoid macular edema after phacoemulsification显示文摘● AIM: To compare the efficacy, tolerability and safety of bromfenac 0.09%, nepafenac 0.1% or diclofenac 0.1% for the prophylaxis of the cystoid macular edema(CME) after phacoemulsification.● METHODS: Group sequential observational comparative study. After phacoemulsification, patients received two months for topical treatment of either diclofenac sodium, bromfenac or nepafenac. All patients received concomitant topical tobramycin 0.3% and topical prednisolone 1%. We measured CME using optical coherence tomography(OCT) central foveal thickness, macular thickness and total macular volume.● RESULTS: We enrolled 243 patients from January to June 2015, and 35% received diclofenac, 32.9% bromfenac and 32.1% nepafenac. When we compared pre-operative to three weeks to two months, bromfenac was more effective in reducing foveal volume(21.3 and 35.4 mm3, respectively), compared with the diclofenac(1.3 and 11.5 mm3, respectively), and the nepafenac group, became more edematous 6.4 and 5.3, respectively. Totally 133 patients completed the post-surgical satisfaction questionnaire. Patients complained of eye stickiness in 13.8% whom we gave nepafenac, versus 10.3% whom we gave diclofenac sodium, and in 0 whom we gave bromfenac.● CONCLUSION: Bromfenac is the best tolerated and is more effective than diclofenac and nepafenac in reducing CME after phacoemulsification. | Ana Maria Chinchurreta Capote Mercedes Lorenzo Soto Francisco Rivas Ruiz Enrique Caso Peláez Alicia Garcia Vazquez Group OftaCosta Antonio Ramos Suárez | 2018 | International Journal of Ophthalmology(English edition)2018，11，7： | 2 |
| 11 | Cost-effectiveness of enhanced liver fibrosis test to assess liver fibrosis in chronic hepatitis C virus and alcoholic liver disease patients显示文摘AIM To assess liver fibrosis(LF) in hepatitis C virus(HCV) and alcoholic liver disease(ALD), estimate health outcomes and costs of new noninvasive testing strategies METHODS A Markov model was developed to simulate LF progression in HCV and ALD for a cohort of 40-yearold men with abnormal levels of transaminases. Three different testing alternatives were studied: a single liver biopsy; annual Enhanced liver fibrosis(ELF?) followed by liver stiffness measurement(LSM) imaging as a confirmation test if the ELF test is positive; and annual ELF test without LSM. The analysis was performed from the perspective of a university hospital in Spain.Clinical data were obtained from published literature. Costs were sourced from administrative databases of the hospital. Deterministic and probabilistic sensitivity analyses were performed.RESULTS In HCV patients, annual sequential ELF test/LSM and annual ELF test alone prevented respectively 12.9 and 13.3 liver fibrosis-related deaths per 100 persons tested, compared to biopsy. The incremental costeffectiveness ratios(ICERs) were respectively €13400 and €11500 per quality-adjusted life year(QALY). In ALD, fibrosis-related deaths decreased by 11.7 and 22.1 per 100 persons tested respectively with sequential ELF test/LSM and annual ELF test alone. ICERs were €280 and €190 per QALY, respectively.CONCLUSION The use of the ELF test with or without a confirmation LSM are cost-effective options compared to a single liver biopsy for testing liver fibrosis in HCV and ALD patients in Spain. | Marcelo Soto Laura Sampietro-Colom Luis Lasalvia Aurea Mira Wladimiro Jiménez Miquel Navasa | 2017 | World Journal of Gastroenterology2017，23，17： | 2 |
| 12 | Meta-analysis on the effectiveness of powered toothbrushes for orthodontic patients显示文摘 | Eleftherios G. Kaklamanos Sotos Kalfas | 2008 | American Journal of Orthodontics & Dentofacial Orthopedics2008，，2： | 2 |
| 13 | Differential responses to artificial selection on oviposition site preferences in Drosophila melanogaster and D. simulans显示文摘在植物昆虫相互作用的偏爱表演关系是在进化生态学的一个中央主题。在许多昆虫之中,鸡蛋是脆弱的,幼虫限制了活动性,使一个适当 oviposition 地点的选择成为为女性的最重要的决定之一。我们由人工地为 2 个自然资源,葡萄和植物的一种为偏爱选择在果蝇 melanogaster Meigen 和果蝇 simulans Sturtevant 调查了 oviposition 偏爱的进化。我们的学习的主要发现是 D 的微分回答。melanogaster 和 D。simulans。尽管偏爱在 D 的试验性的人口演变。melanogaster,回答不与政体使用了的选择一致。相反,在 D 的回答。simulans 与期望一致,证明这种有为特点的可选的基因变化。而且,在 D 之间交叉。simulans 分叉的线证明涉及葡萄偏爱的基因因素看起来大部分后退。在摘要,我们的人工的选择学习建议那 D。melanogaster 和 D。simulans 为这个特点拥有不同基因体系结构。 | Eduardo M. Soto Maria I. L. Betti Juan Hurtado Esteban Hasson | 2015 | Insect Science2015，22，6： | 2 |
| 14 | Imaging of Miscellaneous Pancreatic Pathology (Trauma, Transplant, Infections, and Deposition)显示文摘 | Nagaraj-Setty Holalkere Jorge Soto | 2012 | Radiologic Clinics of North America2012，，3： | 2 |
| 15 | Imaging of blunt pancreatic trauma显示文摘 | Satinder Rekhi Stephan W. Anderson James T. Rhea Jorge A. Soto | 2010 | Emergency Radiology2010，，1： | 2 |
| 16 | Iron Activation of Natural Aluminosilicates to Remove Arsenic from Groundwater显示文摘 | Irma Lia Botto Maria Jose Gonzalez Delia Gazzolli Edgardo Luis Soto | 2013 | Journal of Environmental Science and Engineering(A)2013，2，12： | 2 |
| 17 | The E-screen assay as a tool to identify estrogens:An update on estrogenic environmental pollutants显示文摘 | Soto AM Sonnenschein C Chung KL | 1995 | Environ Health Perspect1995，103，： | 2 |
| 18 | Developing a Marker of exposure to xenoestrogen mixtures in human serum显示文摘 | Soto A M Fernandez M F Luizzi M F | 1997 | Environ Health Perspect1997，105，3： | 2 |
| 19 | A comparative evaluation of microalgae for the degradation of piggery wastewater under photosynthetic oxygenation显示文摘 | Ignacio de Godos Virginia A. Vargas Saúl Blanco María C. García González Roberto Soto Pedro A. García-Encina Eloy Becares Raúl Mu?oz | 2010 | Bioresource Technology2010，，14： | 2 |
| 20 | Involvement of chemokine receptors in breast cancer metastasis显示文摘 | Muller A Hmey B Soto H | | 0，，： | 2 |
您所在的机构暂未开通此部分的功能，请联系管理员