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| 1 | Relationship between dew presence and Bassia dasyphylla plant growth显示文摘Dew has been recognized for its ecological significance and has also been identified as an additional source of water in arid zones.We used factorial control experiment,under dew presence in the field,to explore photosynthetic performance,water status and growth response of desert annual herbage.Bassia dasyphylla seedlings were grown in contrasting dew treatments (dew-absent and dew-present) and different watering regimes (normal and deficient).The effects of dew on the water status and photosynthetic performance of Bassia dasyphylla,grown in a desert area of the Hexi Corridor in Northwestern China,were evaluated.The results indicated the presence of dew significantly increased relative water content (RWC) of shoots and total biomass of plants in both water regimes,and enhanced the diurnal shoot water potential and stomatal conductance in the early morning,as well as photosynthetic rate,which reached its maximum only in the water-stressed regime.The presence of dew increased aboveground growth of plants and photosynthate accumulation in leaves,but decreased the root-to-shoot ratio in both water regimes.Dew may have an important role in improving plant water status and ameliorating the adverse effects of plants exposed to prolonged drought. | YanLi ZHUANG Sophia RATCLIFFE | 2012 | Journal of Arid Land2012,4,1: | 21 |
| 2 | Extensively drug-resistant bacteria are an independent predictive factor of mortality in 130 patients with spontaneous bacterial peritonitis or spontaneous bacteremia显示文摘AIM: To evaluate the epidemiology and outcomes of culture-positive spontaneous bacterial peritonitis(SBP) and spontaneous bacteremia(SB) in decompensated cirrhosis.METHODS: We prospectively collected clinical, laboratory characteristics, type of administered antibiotic, susceptibility and resistance of bacteria to antibiotics in one hundred thirty cases(68.5% males) with positive ascitic fluid and/or blood cultures during the period from January 1, 2012 to May 30, 2014. All patients with SBP had polymorphonuclear cell count in ascitic fluid > 250/mm3. In patients with SB a thorough study did not reveal any other cause of bacteremia. The patients were followed-up for a 30-d periodfollowing diagnosis of the infection. The final outcome of the patients was recorded in the end of follow-up and comparison among 3 groups of patients according to the pattern of drug resistance was performed.RESULTS: Gram-positive-cocci(GPC) were found in half of the cases. The most prevalent organisms in a descending order were Escherichia coli(33), Enterococcus spp(30), Streptococcus spp(25), Klebsiella pneumonia(16), S. aureus(8), Pseudomanas aeruginosa(5), other Gram-negative-bacteria(GNB)(11) and anaerobes(2). Overall, 20.8% of isolates were multidrug-resistant(MDR) and 10% extensively drugresistant(XDR). Health-care-associated(HCA) and/or nosocomial infections were present in 100% of MDR/XDR and in 65.5% of non-DR cases. Meropenem was the empirically prescribed antibiotic in HCA/nosocomial infections showing a drug-resistance rate of 30.7% while third generation cephalosporins of 43.8%. Meropenem was ineffective on both XDR bacteria and Enterococcus faecium(E. faecium). All but one XDR were susceptible to colistin while all GPC(including E. faecium) and the 86% of GNB to tigecycline. Overall 30-d mortality was 37.7%(69.2% for XDR and 34.2% for the rest of the patients)(log rank, P = 0.015). In multivariate analysis, factors adversely affecting outcome included XDR infection(HR = 2.263, 95%CI: 1.005-5.095, P = 0.049), creatinine(HR = 1.125, 95%CI: 1.024-1.236, P = 0.015) and INR(HR =1.553, 95%CI: 1.106-2.180, P = 0.011).CONCLUSION: XDR bacteria are an independent lifethreatening factor in SBP/SB. Strategies aiming at restricting antibiotic overuse and rapid identification of the responsible bacteria could help improve survival. | Alexandra Alexopoulou Larisa Vasilieva Danai Agiasotelli Kyriaki Siranidi Sophia Pouriki Athanasia Tsiriga Marina Toutouza Spyridon P Dourakis | 2016 | World Journal of Gastroenterology2016,22,15: | 19 |
| 3 | Deep Learning Based Single Image Super-resolution:A Survey显示文摘Single image super-resolution has attracted increasing attention and has a wide range of applications in satellite imaging, medical imaging, computer vision, security surveillance imaging, remote sensing, objection detection, and recognition. Recently, deep learning techniques have emerged and blossomed, producing ' the state-of-the-art” in many domains. Due to their capability in feature extraction and mapping, it is very helpful to predict high-frequency details lost in low-resolution images. In this paper, we give an overview of recent advances in deep learning-based models and methods that have been applied to single image super-resolution tasks. We also summarize, compare and discuss various models from the past and present for comprehensive understanding and finally provide open problems and possible directions for future research. | Viet Khanh Ha Jin-Chang Ren Xin-Ying Xu Sophia Zhao Gang Xie Valentin Masero Amir Hussain | 2019 | International Journal of Automation and computing2019,16,4: | 17 |
| 4 | Small for size syndrome following living donor and split liver transplantation显示文摘The field of liver transplantation is limited by the availability of donor organs. The use of living donor and split cadaveric grafts is one potential method of expanding the donor pool. However, primary graft dysfunction can result from the use of partial livers despite the absence of other causes such as vascular obstruction or sepsis. This increasingly recognised phenomenon is termed 'Small-for-size syndrome' (SFSS). Studies in animal models and humans have suggested portal hyperperfusion of the graft combined with poor venous outflow and reduced arterial flow might cause sinusoidal congestion and endothelial dysfunction. Graft related factors such as graft to recipient body weight ratio < 0.8, impaired venous outflow, steatosis > 30% and pro- longed warm/cold ischemia time are positively predictive of SFSS. Donor related factors include deranged liver function tests and prolonged intensive care unit stay greater than five days. Child-Pugh grade C recipients are at relatively greater risk of developing SFSS. Surgi- cal approaches to prevent SFSS fall into two categories: those targeting portal hyperperfusion by reducing inflow to the graft, including splenic artery modulation and portacaval shunts; and those aiming to relieve paren-chymal congestion. This review aims to examine thecontroversial diagnosis of SFSS, including current strate-gies to predict and prevent its occurrence. We will also consider whether such interventions could jeopardize the graft by compromising regeneration. | Hector Daniel Gonzalez Sophia Cashman Giuseppe K Fusai | 2010 | World Journal of Gastrointestinal Surgery2010,2,12: | 13 |
| 5 | SRC-3/AIB1:transcriptional coactivator in oncogenesis显示文摘类固醇受体 coactivator-3 (SRC-3,也作为 NCoA3, AIB1, p/CIP, RAC3, ACTR,和 TRAM1 知道) ,在一个经常放大的区域上局部性, 20q12,与多重癌症被联系了包括胸,胃并且前列腺癌症。尽管 SRC-3 作为 oncogene 被含有,引人注目的证据仅仅最近出现了含有它作为在人的癌症的开始的一个原因的因素。这里,我们总结显示异常 SRC-3 表示在荷尔蒙敏感、感觉迟钝的人的癌症是重要的最近的证据。 | Jun YAN Sophia Y TSAI Ming-jer TSAI | 2006 | Acta Pharmacologica Sinica2006,27,4: | 12 |
| 6 | 3种方法检测粪便中溶组织内阿米巴的结果比较显示文摘目的比较生理盐水直接涂片法、醛醚沉淀法及ELISA 3种方法检测粪便中溶组织内阿米巴的优缺点。方法采集受检者粪便标本278份.分别采用3种方法进行阿米巴原虫感染检测,检测结果进行统计学处理,分析3种方法的阳性检出率、准确率、敏感性、特异性及费用。结果生理盐水直接涂片法、醛醚沉淀法和ELISA法的阳性率分别为9.71%、10.79%和12.23%,差异无统计学意义(P>0.05);阳性标本经PCR确证,3种方法的阳性符合率分别为48.71%、51.11%和77.36%,差异有统计学意义(P<0.05)。生理盐水直接涂片法费用低(1元/份),耗时少(0.1 h~0.2 h)。结论粪便溶组织内阿米巴检测推荐使用ELISA法,其次是醛醚沉淀法,如果用生理盐水涂片法,至少要重复检测3次。 | 刘慧 孙晓东 聂仁华 邓艳 沈旭 Sophia Manue 郭晓芳 李春富 杨亚明 李崇珍 张苍林 | 2008 | 中国病原生物学杂志2008,3,9: | 12 |
| 7 | Obstructive sleep apnea syndrome and cardiovascular disease: The influence of C-reactive protein显示文摘Obstructive sleep apnea syndrome(OSAS) is a common medical condition, associated with atherosclerosis and cardiovascular disease(CVD). The underlying pathophysiologic mechanisms of this association have not been completely understood and may be multifactorial in origin. A number of studies suggest that inflammatory processes have emerged critical in the pathogenesis of CVD in OSAS. A range of circulating inflammatory molecules has been identified and measured, with a view to assess inflammation and predict vascular damage risk, such as plasma cytokines, adhesion molecules, and C-reactive protein(CRP). CRP is a relevant marker worthy of further study, because not only is elevated in patients with OSAS, but also is rapidly becoming a risk factor for cardiac disease. Furthermore, in selected OSAS patients, aggressive treatment of the disorder may lead to retarding or even improvement of CVD progression. However, still there is a debate on the true correlation between CRP and OSAS, as well as the clinical effect of any reduction after OSAS treatment. Further research is required to define those OSAS patients who will have a considerable reduction with treatment, as well as to understand the significance of the interaction between cardiovascular risk factor and CRP reduction in patients with OSAS. | Izolde Bouloukaki Charalampos Mermigkis Eleftherios M Kallergis Violeta Moniaki Eleni Mauroudi Sophia E Schiza | 2015 | World Journal of Experimental Medicine2015,5,2: | 12 |
| 8 | Therapeutic regulation of autophagy in hepatic metabolism显示文摘Metabolic homeostasis requires dynamic catabolic and anabolic processes. Autophagy, an intracellular lysosomal degradative pathway, can rewire cellular metabolism linking catabolic to anabolic processes and thus sustain homeostasis. This is especially relevant in the liver, a key metabolic organ thatgoverns body energy metabolism. Autophagy’s role in hepatic energy regulation has just begun to emerge and autophagy seems to have a much broader impact than what has been appreciated in the field. Though classically known for selective or bulk degradation of cellular components or energy-dense macromolecules, emerging evidence indicates autophagy selectively regulates various signaling proteins to directly impact the expression levels of metabolic enzymes or their upstream regulators. Hence, we review three specific mechanisms by which autophagy can regulate metabolism: A) nutrient regeneration, B) quality control of organelles, and C) signaling protein regulation. The plasticity of the autophagic function is unraveling a new therapeutic approach. Thus, we will also discuss the potential translation of promising preclinical data on autophagy modulation into therapeutic strategies that can be used in the clinic to treat common metabolic disorders. | Katherine Byrnes Sophia Blessinger Niani Tiaye Bailey Russell Scaife Gang Liu Bilon Khambu | 2022 | Acta Pharmaceutica Sinica B2022,12,1: | 11 |
| 9 | 吡啶硫酮锌在乳胶漆中的防霉抗藻性研究显示文摘对比了各种防霉抗藻剂单体的化学结构式及优缺点,以及它们在乳胶漆中的防霉抗藻性比较,通过对不同种类防霉抗藻剂的性能实验及环保性法规探讨,研究了吡啶硫酮锌在乳胶漆中的应用前景。 | 张熠 陈炳耀 陈明毅 刘伟 徐野 Sophia Ge | 2012 | 涂料工业2012,42,1: | 10 |
| 10 | Anterograde and Retrograde Regulation of Nuclear Genes Encoding Mitochondrial Proteins during Growth, Development, and Stress显示文摘在植物的 Mitochondrial 生物的续生说和功能要求编码 mitochondrial 蛋白质(NGEMP ) 的超过 1000 原子基因的表示。这些基因的表达式被织物特定、发展、内部、外部的刺激 thatresult 在涉及的一个动态细胞器调整新陈代谢并且许多发信号的进程。尽管线粒体的新陈代谢的 andbiosynthetic 机械很好相对被理解,调整这些过程和 varioussignaling 小径的因素仅仅在分子的水平正在识别包含。anterograde 的分子的部件(对 mitochondrial 原子) 并且后退(mitochondrial 到原子) 与叶绿体调整 NGEMPsinteract 的表示的发信号的小径 -- ,生长 -- ,并且在在许多层次的房间的发信号压力的小径,与在这些信号的传播和执行的普通 componentsinvolved。这作为在 thecell,不是仅仅在 mitochondrial 功能本身的直接发信号,而且在察觉到或集成许多 otherinternal 和外部信号发信号的重要中心放线粒体。这与精力新陈代谢和压力回答集成并且优化生长,哪个在光合、非光合的 cells.Key 词的 isrequired: | Sophia Ng Inge De Clercqc Olivier Van Akena Simon R. Lawd Aneta Ivanovad Patrick Willems Estelle Giraud Frank Van Breusegem James Wheland | 2014 | Molecular Plant2014,7,7: | 8 |
| 11 | Collagen/hyaluronan based hydrogels releasing sulfated hyaluronan improve dermal wound healing in diabetic mice via reducing inflammatory macrophage activity显示文摘Sustained inflammation associated with dysregulated macrophage activation prevents tissue formation and healing of chronic wounds.Control of inflammation and immune cell functions thus represents a promising approach in the development of advanced therapeutic strategies.Here we describe immunomodulatory hyaluronan/collagen(HA-AC/coll)-based hydrogels containing high-sulfated hyaluronan(sHA)as immunoregulatory component for the modulation of inflammatory macrophage activities in disturbed wound healing.Solute sHA downregulates inflammatory activities of bone marrow-derived and tissue-resident macrophages in vitro.This further affects macrophage-mediated pro-inflammatory activation of skin cells as shown in skin ex-vivo cultures.In a mouse model of acute skin inflammation,intradermal injection of sHA downregulates the inflammatory processes in the skin.This is associated with the promotion of an anti-inflammatory gene signature in skin macrophages indicating a shift of their activation profile.For in vivo translation,we designed HA-AC/coll hydrogels allowing delivery of sHA into wounds over a period of at least one week.Their immunoregulatory capacity was analyzed in a translational experimental approach in skin wounds of diabetic db/db mice,an established model for disturbed wound healing.The sHA-releasing hydrogels improved defective tissue repair with reduced inflammation,augmented pro-regenerative macrophage activation,increased vascularization,and accelerated new tissue formation and wound closure. | Sophia Hauck Paula Zager Norbert Halfter Elke Wandel Marta Torregrossa Ainur Kakpenova Sandra Rother Michelle Ordieres Susann Räthel Albrecht Berg Stephanie Möller Matthias Schnabelrauch Jan C.Simon Vera Hintze Sandra Franz | 2021 | Bioactive Materials2021,6,12: | 7 |
| 12 | 孕早期子宫动脉血流动力学参数对反复妊娠丢失患者妊娠结局的预测价值显示文摘目的探讨孕早期子宫动脉血流动力学参数监测对反复妊娠丢失(recurrent pregnancy loss,RPL)患者妊娠结局的预测价值。方法回顾性分析2017年11月至2018年5月期间就诊于同济大学附属第一妇婴保健院生殖免疫科的RPL患者资料,采用病例对照研究设计,按照RPL妊娠结局将患者分为活产组和流产组,分析两组患者在孕早期子宫动脉血流动力学参数的差异。结果研究纳入活产组348例,流产组312例。随孕周增加,子宫动脉收缩期峰值/舒张末期流速(peak uterine artery systolic/end-diastolic velocity,S/D)、搏动指数(pulsatility index,PI)及血流阻力指数(blood flow resistance index,RI)在两组中均呈下降趋势;与流产组相比,活产组子宫动脉S/D、PI和RI分别多下降3.4621(95%CI=-6.4835~0.4408,P=0.0252)、0.4742(95%CI=-1.0005~0.0521,P=0.0781)和0.0546(95%CI=-0.1115~0.0024,P=0.0609),孕早期活产组子宫动脉S/D、PI和RI下降速率较流产组高0.0645(95%CI=0.0136~0.1159,P=0.0145)、0.0094(95%CI=0.0005~0.0184,P=0.0394)和0.0011(95%CI=0.0001~0.0020,P=0.0322)。结论活产组子宫动脉血流参数下降速率较流产组更快,早孕期监测子宫动脉血流动力学对RPL患者妊娠结局具有预测价值。 | 张敏 阮加里 Frempong Sophia Twum 鲍时华 | 2021 | 中华生殖与避孕杂志2021,41,7: | 7 |
| 13 | 中国四川省视力损伤及盲的原因和发病率(英文)显示文摘目的:了解四川省低视力及盲的原因和发病率。方法:分层多阶段及随机抽样调查38个县市40351户125641人,进行全面眼部检查,包括标准对数视力表检测视力,发病率以年龄和性别为标准根据2000年中国人口普查结果进行分析。结果:盲率0.77%(95%可信区间:0.72~0.82,n=966),低视力率1.22%(95%可信区间1.14~1.27,n=1513)。视力残疾率城市1.40%,农村2.22%(P<0.01),白内障无论城市还是农村均是首位致残原因(55.7%,n=1381),视网膜疾病居第二(9.7%,n=236),但是城市明显高于农村(34.3%vs2.7%,P<0.01)。角膜病居第三(6.5%,n=161),农村明显多于城市(7.2%vs3.9%,P=0.006)。结论:四川省估计有约172万视力残疾患者,其中52.5万盲人,防盲重心在农村。 | 魏敏 陈辉 樊映川 Sophia Pathai | 2010 | 国际眼科杂志2010,10,1: | 7 |
| 14 | The role of the orphan nuclear receptor COUP-TFII in tumorigenesis显示文摘The chicken ovalbumin upstream promoter transcription factors (COUP-TFs), members of the nuclear receptor superfamily, consist of two highly homologous subtypes, COUP-TFI (EAR-3, NR2F1) and COUP-TFII (ARP-1, NR2F2). They are referred to as orphan receptors because the COUP-TF ligands have yet to be identified. Since the discovery of COUP-TFs in 1986, extensive studies have demonstrated their crucial functions in a variety of developmental processes, such as organogenesis, angiogenesis, and metabolic homeostasis. Recently, emerging evidence has highlighted that COUP-TFs, specifically COUP-TFII, play important roles in tumorigenesis. In this review, we will discuss the critical functions of COUP-TFII in the development of the tumor microenvironment, the progression of various cancers, and its underlying mechanisms. | Mafei XU lun QIN Sophia Y TSAI Ming-jer TSAI | 2015 | Acta Pharmacologica Sinica2015,36,1: | 6 |
| 15 | n-Butylidenephthalide induced apoptosis in the A549 human lung adenocarcinoma cell line by coupled down-regulation of AP-2α and telomerase activity显示文摘 | Chyou-wei WEI Chai-ching LIN Yung-luen YU Chai-yi LIN Po-cheng LIN Min-tze WU Cheng-jueng CHEN Wen-liang CHANG Shinn-zong LIN Yi-lin Sophia CHEN Horng-jyh HARN | 2009 | Acta Pharmacologica Sinica2009,30,9: | 5 |
| 16 | 健康婴幼儿及儿童心电图时间参数的比较显示文摘目的比较不同年龄和性别健康婴幼儿及儿童心电图(ECG)时间参数的特点,评估现有国内外健康婴幼儿及儿童ECG标准应用于我国儿童的可行性。方法记录上海地区1557名健康婴幼儿和儿童(男812例,女745例;年龄1~17岁)ECG的心率(HR)、P波时间、P-R间期、QRS波时间、Q-T间期、Q-R峰值时间,并在不同年龄组及男女组间进行比较。结果HR、P波时间、P-R间期、QRS波时间、Q-T间期、校正Q-T间期(QTc)、QT离散度(QTd)及Q-R峰值时间在各年龄组间均有显著性差异(Pa<0.001),P波时间、P-R间期、QRS波时间及Q-T间期均与年龄呈正相关,与HR呈负相关(Pa<0.001)。部分测量值男女组间以及与既往标准间的差异均有统计学意义(Pa<0.05)。结论健康婴幼儿及儿童ECG时间参数具有年龄、性别、时间和种族差异。沿用传统的国内外健康婴幼儿及儿童ECG标准不合适,有必要修订更新传统的正常值标准,并应重视年龄、性别间的差异。与之相关的疾病诊断标准也应进行修订。 | 周弋 李奋 孙锟 Sophia Zhou 李筠 杨健萍 朱敏 邢海华 | 2008 | 实用儿科临床杂志2008,23,19: | 5 |
| 17 | 溶组织内阿米巴ELISA试剂盒在阿米巴病调查的应用显示文摘目的了解景洪市爱尼族人群阿米巴病流行情况,为阿米巴病监测和防治提供依据,并评价ELISA试剂盒在阿米巴病调查应用的效果。方法以整群随机抽样爱尼族村寨,逐户收集新鲜粪便标本,用观察法、碘液涂片镜检法和TECHLAB第二代溶组织内阿米巴ELISA试剂盒对照检测粪便标本溶内阿米巴。结果镜检278例,E·h/E·d感染为9·71%;ELISA检测366例,E·h感染率为9·29%;镜检和ELISA共同阳性15例,占镜检阳性的55·56%;粪便观察和ELISA检测结果诊断5例为肠阿米巴病,发病率为1·37%,E·h致病率为14·71%。结论景洪爱尼族阿米巴病流行严重,应加强阿米巴病的监测和防治工作,同时积极推广新技术。 | 孙晓东 Sophia Manue 张晓阳 刘惠 邓艳 杨亚明 汪丽波 李春富 郭晓芳 张苍林 | 2006 | 中国热带医学2006,6,11: | 5 |
| 18 | Acute pancreatitis in aging animals:Loss of pancreatitis-associated protein protection?显示文摘AIM:To investigate the effect of age on severity of acute pancreatitis(AP) using biochemical markers,histology and expression of the protective pancreatitisassociated proteins(PAPs).METHODS:AP was induced via intraductal injection of 4% sodium taurocholate in young and old rats.Sera and pancreata were assayed at 24 h for the parameters listed above;we also employed a novel molecular technique to assess bacterial infiltration using polymerase chain reaction to measure bacterial genomic ribosomal RNA.RESULTS:At 24 h after induction of AP,the pancreata of older animals had less edema(mean ± SE histologic score of young vs old:3.11 ± 0.16 vs 2.50 ±-0.11,P < 0.05),decreased local inflammatory response(histologic score of stromal infiltrate:3.11 ± 0.27 vs 2.00 ± 0.17,P < 0.05) and increased bacterial infiltration(174% ± 52% increase from sham vs 377% ± 4%,P < 0.05).A decreased expression of PAP1 and PAP2 was demonstrated by Western blotting analysis and immunohistochemical staining.There were no differences in serum amylase and lipase activity,or tissue myeloperoxidase or monocyte chemotactic protein-1 levels.However,in the most-aged group,serum C-reactive protein levels were higher(young vs old:0.249 ± 0.04 mg/dL vs 2.45 ± 0.68 mg/dL,P < 0.05).CONCLUSION:In older animals,there is depressed PAP expression related to a blunted inflammatory response in AP which is associated with worsened bacterial infiltration and higher C-reactive protein level;this may explain the more aggressive clinical course. | Sophia Fu Albert Stanek Cathy M Mueller Nefertti A Brown Chongmin Huan Martin H Bluth Michael E Zenilman | 2012 | World Journal of Gastroenterology2012,18,26: | 5 |
| 19 | 标准肢体导联和Mason-Likar肢体导联心电图波段的定量比较显示文摘目的在正常中国人中,对标准导联和Mason-Likar导联所记录肢体导联心电图的波段进行定量比较。方法经冠脉造影和心脏超声检查结果均正常者共84例,列为正常人。结果两类导联系统所记录的心电图存在良好的相关性,但也存在显著性差异。与标准肢体导联相比,Mason-Likar肢体导联心电图的差异包括:①心电轴右偏,平均增加23.3±26.7度;②II、III和aVF导联中R波和QRS波振幅显著增加,ST段显著下移,III和aVF导联T波振幅降低或T波转为倒置,其中III导联变化最大;③I和aVL导联QRS波振幅显著增加,ST段显著上移伴T波振幅增加。与心电图改变有关的相关性包括:①R波振幅改变与QRS波电轴偏移存在相关性;②ST80ms和T波振幅与T波电轴偏移存在相关性,与QRS波振幅改变也存在相关性。结论应充分认识两类导联系统所记录心电图的差异性。 | 刘霞 金琳 郭芳 Sophia Zhou | 2007 | 临床心电学杂志2007,16,6: | 5 |
| 20 | 右胸导联V_(4R)和V_(5R)对由右冠脉近段阻塞引起的急性ST段抬高型心肌梗死的诊断价值显示文摘目的与右冠脉阻塞关联的ST段抬高型右室心肌梗死,住院期死亡率高。本研究假设是:右胸导联(V4R和V5R导联)有助于发现ST段抬高型右室心肌梗死。1342例患者记录12导联加右胸导联心电图。结果右冠脉近段阻塞者,V4R和V5R导联常见有ST段抬高,同时伴有Ⅰ,aVL,V5和V6导联ST段压低;常规12导联心电图通常不能发现ST段抬高。结论对于急性冠脉综合征,提高对ST段抬高型心肌梗死诊断的敏感性,常规12导联附加右胸导联是一项简便的方法。 | 刘霞 Sophia Zhou 邱慷 郭芳 沈卫峰 | 2006 | 临床心电学杂志2006,15,3: | 5 |