|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Hepatoprotective activity of brown alga Padina boergesenii against CCl_4 induced oxidative damage in Wistar rats显示文摘Objective:To investigate the protective effects of brown alga Padina boergesenii(P.boergeseii) against carbon tetrachloride(CCl4) induced oxidative damage and liver fibrosis in rats.Methods: To assess the hepatic damage liver weight,the activities of TBARS level,glutathione,SOD,CAT and GPx in circulation and liver.Results:The group of rats induced with CCl4 alone(2 mL/kg body weight),showed noticeable increase in the liver weight and TBARS level.Followed by, the level of antioxidant enzymes glutathione peroxidase,Superoxide dismutase and catalase was also significantly(P<0.01) diminished.Where as,the rats pretreated with P.boergesenii(150 mg/ kg body weight) modulated the CCl4 induced liver fibrosis.The level of antioxidant enzymes and lipid peroxidation products was found to be significandy(P<0.01) attenuated to near normal level, when compared with rats induced with CCL,alone.In order to assess the role of carotenoids in the relevant activity,total carotenoid content of the extract was analysed and found to be 0.59 mg/g fresh weight(FW).Further,the histopathogical studies provide a supportive evidence for this study to show the protective nature of P.boergesenii.Conclusions:The protective role of brown alga P.boergesenii extract has confirmed its potential activity through its antioxidant sparing actions against CCl4 induced free radical damage.However,the possible mechanism of hepatoprotection is rather speculative at this stage and investigations are underway to isolate and characterize the bioactive compounds from P.boergesenii. | Rajamani Karthikeyan ST Somasundaram T Manivasagam T Balasubramanian P Anantharaman | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，9： | 6 |
| 2 | Isolation and characterization of acid and pepsin-solubilized collagen from the skin of sailfish (Istiophorus platyp- terus)显示文摘 | Somasundaram T Anguchamy V Muthuvel A | 2013 | Food Research International2013，54，： | 1 |
| 3 | Automatic brain extraction methods for TI magnetic resonance images using region labeling and morphological operations显示文摘 | SOMASUNDARAM K KALAISELVI T | 2011 | Computers in Biology and Medicine2011，41，8： | 1 |
| 4 | Dietary curcumin inhibits chemotherapy-induced apoptosis in models of human breast cancer 显示文摘 | Somasundaram S Edmund N A Moore D T | 2002 | Cancer research2002，62，13： | 1 |
| 5 | An atomic resolution structure for human fibroblast growth factor 1显示文摘 | BERNETT M J SOMASUNDARAM T BLABER M | 2004 | Proteins2004，57，3： | 1 |
| 6 | Pseudonyms Based Blind Signature Approach for an Improved Secured Communication at Social Spots in VANETs 显示文摘 | Thenmozhi T Somasundaram R M | 2015 | Wireless Personal Communications2015，82，： | 1 |
| 7 | Transition state structure of arginine kinase: implications for catalysis of bimolecular reactions显示文摘 | Zhoug Somasundaram T Blanc E | 1998 | Proc Natl Acad Sci USA1998，95，15： | 1 |
| 8 | Cytotoxic T-cell memory without antigen显示文摘 | Lau LL Jamieson BD Somasundaram T | 1994 | Nature1994，369，6482： | 1 |
| 9 | OPF with FACTS De- vices in Interconnected Power Systems Using Fuzzy Stochastic Al- gorithms显示文摘 | PRASANNA T S SOMASUNDARAM P | 2009 | International Journal of Power and Energy Conver- sion2009，1，23： | 1 |
| 10 | Transition structure of argininge kinase:implications for catalysis of bimolecular reactions显示文摘 | Zhou G Somasundaram T Blanc E | | 0，，： | 1 |
| 11 | Occurrence of atrazine and degradates as contaminants of subsurface drainage and shallow groundwater显示文摘 | Jayachandran K Steinheimer T R Somasundaram L | 1994 | J Environ Qual1994，23，： | 1 |
| 12 | Propagation of Casuarina equisetiflolia forest by planting shoots 显示文摘 | Somasundaram T R Jagadees S | 1977 | Indian Forester1977，103，： | 1 |
| 13 | DDoS defense system for Web services in a cloud environment 显示文摘 | Vissers T Somasundaram T S Pieters L | 2014 | Future Generation Computer Systems2014，37，： | 1 |
| 14 | Melanoma-Derived Conditioned Media Efficiently Induce the Differentiation of Monocytes to Macrophages that Display a Highly Invasive Gene Signature显示文摘 | Wang T Ge Y Xiao M Lopez-Coral A Azuma R Somasundaram R Zhang G Wei Z Xu X Rauscher Iii F J | | 0，，： | 1 |
| 15 | Cytotoxic T-cell memory without antigen 显示文摘 | Lau LL Jamieson BD Somasundaram T | 1994 | Nature1994，369，6482： | 1 |
| 16 | The passage of gases through the liquid water vapour interface:a simulation study显示文摘 | SOMASUNDARAM T LYNDEN-BELL R M PATTERSON C H | 1999 | Phys Chem Chem Phys1999，1，1： | 1 |
| 17 | Low molecular weight molluscan glycosaminoglycan from bivalve Katelysia opima (Gmelin) 显示文摘 | Vijayabaskar P Balasubrarnanian T Somasundaram ST | 2008 | Methods Find Exp Clin PharmacoL2008，30，3： | 1 |
| 18 | Breast cancer and human papillomavirus infection:no evidence of HPV etiology of breast cancer in Indian women显示文摘 | Hedau S Kumar U Hussain S Shukla S Pande S Jain N Tyagi A Deshpande T Bhat D Mir MM Chakraborty S Singh YM Kumar R Somasundaram K Bharti AC Das BC | 2011 | BMC Cancer2011，11，： | 1 |
| 19 | A simulation study of the kinetics of passage of CO_2 and N_2 through the liquid/vapor interface of water显示文摘 | SOMASUNDARAM T PANHUIS M I H LYNDENBELL R M | 1999 | J Chem Phys1999，111，5： | 1 |
| 20 | Developmentally dictated expression of heat shock factors : exclusive expression of HSF4 in the postnatal lens and its specific interaction with alphaB-crystallin heat shock promoter 显示文摘 | Somasundaram T Bhat SP | 2004 | J Biol Chem2004，279，44： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员