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| 1 | Hepatitis B virus prevalence and transmission risk factors in inflammatory bowel disease patients at Clementino Fraga Filho university hospital显示文摘AIM: To evaluate the prevalence of hepatitis B virus (HBV) infection in inflammatory bowel disease (IBD) patients that followed up in our hospital and try to identify the possible risk factors involved in this infection transmission. METHODS: This was a cross-sectional study for which 176 patients were selected according to their arrival for the medical interview. All these patients had already IBD diagnosis. The patient was interviewed and a questionnaire was filled out. RESULTS: In the group of 176 patients whom we examined, we found that 17% (30) were anti-HBc positive. Out of 30 patients with positive anti-HBc, 2.3% (4) had positive HBsAg and negative HBV-DNA. In an attempt to identify the possible HBV infection transmission risk factors in IBD patients, it was observed that 117 patients had been submitted to some kind of surgical procedure, but only 24 patients had positive anti-HBc (P = 0.085). It was also observed that surgery to treat IBD complications was not a risk factor for HBV infection transmission, since we did not get a statically significant P value. However, IBDpatients that have been submitted to surgery to treat IBD complications received more blood transfusions then patients submitted to other surgical interventions (P = 0.015). CONCLUSION: There was a high incidence of positive anti-HBc (17%) and positive HBsAg (2.3%) in IBD patient when compared with the overall population (7.9%). | Yolanda Faia Manhes Tolentino Homero Soares Fogaa Cyrla Zaltman Lia Laura Lewis Ximenes Henrique Sérgio Moraes Coelho | 2008 | World Journal of Gastroenterology2008，14，20： | 10 |
| 2 | Bartter's syndrome:clinical findings,genetic causes and therapeutic approach显示文摘Backgound Bartter's syndrome(BS)is a rare group of salt losing tubulopathies due to the impairment of transport mecha-nisms at the thick ascending limb of the Henle's loop.Data sources Literature reviews and original research articles were collected from database,including PubMed and Scopus.Results According to the time of onset and symptoms,BS can be classified into antenatal and classic BS.Molecular studies have identified different subtypes of BS.BS types Ⅰ,Ⅱ and Ⅲ are caused by mutations on genes encoding the luminal Na^(+)-K^(+)-2Cl^(-) co-transporter,the luminal K+ channel ROMK,and the basolateral chloride channel ClC-Kb(CLCNKB),respectively.Loss-of-function mutations of Barttin CLCNK type accessory beta subunit cause BS type Ⅳa.Simultaneous mutations of CLCNKB and CLCNKA cause BS type Ⅳb.BS type Ⅴ consists in a novel transient form characterized by antenatal presentation due to mutations in the MAGE family member D2.Severe gain-of-function mutations of the extracellular calcium sensing receptor gene can result in an autosomal dominant condition of BS.Main clinical and biochemical alterations in BS include polyuria,dehydration,hypokalemia,hypochloremic metabolic alka-losis,hyperreninemia,high levels of prostaglandins,normal or low blood pressure,hypercalciuria and failure to thrive.Treatment focuses mainly at correcting dehydration and electrolyte disturbances and in measures to reduce polyuria,including the use of nonsteroidal anti-inflammatory medications to control excessive renal prostaglandin E2 production.Conclusions Early diagnosis and treatment of BS may prevent long-term consequences such as growth failure,nephrocal-cinosis and end-stage renal disease. | Flavia Cristina Carvalho Mrad Sílvia Bouissou Morais Soares Luiz Alberto Wanderley de Menezes Silva Pedro Versiani dos Anjos Menezes Ana Cristina Simoes-e-Silva | 2021 | World Journal of Pediatrics2021，17，1： | 10 |
| 3 | 中医药在巴西的发展现状与分析显示文摘巴西医疗保险以统一医疗体系(Unified Health System,SUS)的免费医疗为主、私人保险为补充,已实现全民享有基本医疗服务。导致该国居民死亡的主要疾病是缺血性心脏病、脑卒中、下呼吸道感染,近年来AD、慢性肾脏病及糖尿病的发病率显著增高。以针灸为代表的中医疗法在19世纪初传入巴西,目前针灸治疗已得到较广泛的认可和应用,被纳入SUS,并在多所高校开设相关课程,但中医药整体特色有待加强,从业人员对中药的理解、运用不足,以及中医药教育缺乏规范等问题限制了中医药在巴西的发展。建议通过发挥中医药治未病的特色,加大中药研发力度并扩大市场,规范中医教育等措施,促进两国在中医药领域的广泛合作,推动中医药在巴西的发展与传播。 | 李皓月 党迎迎 Thaís Salles Araujo Fatima Terezinha Pelachini Farias Jaime Amador Soares Graciela Mendonça da Silva de Medeiros 于涛 魏竞竞 赵静 许家杰 曹洪欣 | 2021 | 国际中医中药杂志2021，43，5： | 5 |
| 4 | Acute pancreatitis and COVID-19:A literature review显示文摘BACKGROUND Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is responsible for the ongoing pandemic of coronavirus disease 2019(COVID-19),and has caused more than 80 million infections and 1.7 million deaths worldwide.Although it is primarily a respiratory virus,SARS-CoV-2 also has extra-pulmonary effects.Pancreatic injury and cases of acute pancreatitis(AP)have been recognized and attributed to SARS-CoV-2,but the mechanisms of pancreatic injury are still a subject of debate.There is also controversy on whether SARS-CoV-2 can cause AP or if it is an epiphenomenon.AIM To review and to explore the relationship between SARS-CoV-2 infection and AP,and to provide an overview of the existing literature on possible mechanisms of SARS-CoV-2-induced pancreatic lesion.METHODS A systematic review was conducted in accordance with PRISMA guidelines for papers on SARS-CoV-2 infection and AP.A narrative review on possible mechanisms of SARS-CoV-2-induced pancreatic lesion was also performed.RESULTS A literature review revealed a growing body of evidence on SARS-CoV-2-induced pancreatic lesions including the mechanisms of direct virus-mediated injury,systemic inflammatory response and circulating pro-inflammatory interleukins,virus-induced lipotoxicity,and drug-induced injury.A systematic review of the literature revealed 22 cases of AP in COVID-19 patients.However,limitations of the reported cases make it difficult to establish a causal relationship between SARS-CoV-2 infection and AP.All of the studies agreed on special monitoring and surveillance of this subset of patients due to the still unknown clinical progression,therapeutic implications,and prognosis.CONCLUSION AP should be considered in COVID-19 patients,especially in those exhibiting abdominal pain and systematic,and complete reporting of these cases should be general practice.However,there is still insufficient evidence showing that COVID-19 can cause AP or negatively impact prognosis.Additional studies are needed to clarify the relationship between these two entities and their theragnostic significance. | Tiago Correia de Sá Carlos Soares Mónica Rocha | 2021 | World Journal of Gastrointestinal Surgery2021，13，6： | 2 |
| 5 | Abeliovich a denitrification in laboratory sandy columms: Carbon regime, gas accumulation and hydraulic prodraulic properties显示文摘 | Soares M I M Braester C Belkin S | 1991 | Water Research1991，25，3： | 2 |
| 6 | Wheat straw as substrate for water denitrification显示文摘 | M.Inês M Soares Aharon Abeliovich | 1998 | Water Research1998，，12： | 2 |
| 7 | A SYBR Green real-time PCR assay to detect and quantify pork meat in processed poultry meat products显示文摘 | Sónia Soares Joana S. Amaral M. Beatriz P.P. Oliveira Isabel Mafra | 2013 | Meat Science2013，，1： | 2 |
| 8 | Dinamica-a stochastic cellular automata model designed to simulate the landscape dynamics in an Amazonian colonization frontier显示文摘 | Soares B S Cerqueira G C Pennachin C L | 2002 | Ecological Modelling2002，154，3： | 1 |
| 9 | A graphical user interface for variable selection employing the successive projections algorithm显示文摘 | PAIVA H M SOARES S F C GALVAO R K H | 2012 | Chemometrics and Intelligent Laboratory Systems2012，118，15： | 1 |
| 10 | A SYBR green real-time PCR assay to detect and quantify pork meat in processed poultry meat products显示文摘 | SOARES S AMARAL J S OLIVEIRA M B P P | 2013 | Meat Science2013，94，： | 1 |
| 11 | Contact indentation of marine composites显示文摘 | Sutherland L S Soares C G | 2005 | Composite Structures2005，70，3： | 1 |
| 12 | Corrosion resistant of a Zn-Ni electrodeposited alloy obtained with a controlled flow and gelatin additive 显示文摘 | SOARES M N SOUZA C A C KURI S E | 2006 | Surf Coat Technol2006，201，： | 1 |
| 13 | An array of possibilities for the study of autoimmunity显示文摘 | FATHMAN C G SOARES L CHAN S M | 2005 | Nature2005，435，7042： | 1 |
| 14 | Evidence for the notch signaling pathway on the role of estrogen in an giogenesis显示文摘 | Soares R Balogh G Guo S | 2004 | Mol Endocrinol2004，18，9： | 1 |
| 15 | Simple and rapid method determination for metformin in human plasma using high performance liquid chromatography tandem mass spectrometry: application to pharmacokinetic studies 显示文摘 | S'lpoli Marques M A Soares A S Pinto O W | 2007 | Chromatography B2007，852，： | 1 |
| 16 | Quantitative detection of poultry meat adulteration with pork by a duplex PCR assay 显示文摘 | Soares S Amaral JS M afra l | 2010 | Meat Sci2010，85，3： | 1 |
| 17 | Develop- ment and evaluation of an edible antimicrobial film based on yam starch and chitosan 显示文摘 | Durango A M Soares N F Benevides S | 2006 | Packaging Technology and Science2006，19，1： | 1 |
| 18 | Aging effect on the reflectivity measurements of polychloroprene matrices containing carbon black and carbonyl-iron powder显示文摘 | Pinho M S Gregori M L Nunes R C R Soares B G | 2001 | Polymer Degradation and Stability2001，73，： | 1 |
| 19 | 17β- estradiol-mediated vessel assembly and stabilization in tumor angiugenesis requires TGFβ and EGFR crosstalk 显示文摘 | Soares R Guo S Gartner F | 2003 | Angiogenesis2003，6，4： | 1 |
| 20 | lntraguild predation between the aphidophagous ladybird beetles Harmonia axyridis and Coccinella undecimpunctata (Coleoptera: Coccinellidae): the role of body weight显示文摘 | Fdlix S Soares A O | 2004 | European Journal of Entomology2004，101，2： | 1 |
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