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| 1 | 沼液灌溉对紫色土菜地土壤特性的影响显示文摘三峡库区山地城镇重肥效的沼液灌溉,既需做到能够充分利用粪污资源,又要不破坏植物的生长与土壤环境。试验采用某大型奶牛养殖场粪污处理站不同阶段的废水进行灌溉,其中包括:沉砂池污水(grit chamber wastewater,GCW)、集水池污水(collection basin wastewater,CBW)、厌氧池沼液(anaerobic tank wastewater,ATW)、好氧池出水(aerobic effluent,AE),并以清水(clean water,CW)作为对照组,5组试验平行同步对紫色土试验样地进行灌溉。土壤剖面铵态氮含量在0~5cm土层ATW为最大860mg/kg,5~10cm土层5个试验组含量略有升高,10~20cm土层试验组GCW、CBW、ATW、AE呈下降趋势。硝态氮含量在0~5cm土层仍是ATW最大为23.95mg/kg。有效磷在0~5cm土层5组试验都低于100mg/kg,5~10cm土层试验组CBW和CW含量上升较大分别为10%和11%,5个试验组总体磷吸收能力都为弱。在沼灌土壤自身承载量的试验中,土壤承载铵态氮最大值为1355mg/kg,硝态氮24.65mg/kg,有效磷为163.66mg/kg,磷吸收系数在第5~9d高于500。通过前期不同阶段污水灌溉研究氮、磷积累吸附及土壤自身承载力的试验,确定沼液灌溉能提供较多有效氮、磷的优良可行性,并为进一步提出合理灌溉量和实际操作提供指导。 | 余薇薇 张智 罗苏蓉 毕生兰 Naresh Singhal | 2012 | 农业工程学报2012，28，16： | 20 |
| 2 | Anti-tumor activity of thalidomide in refractory multiple myeloma显示文摘 | Singhal S Mehta J Desikan R | | 0，，： | 8 |
| 3 | Laparoscopic liver resection for benign and malignant liver tumors显示文摘BACKGROUND:Laparoscopic liver resection is one of the most complex procedures in hepatobiliary surgery.In the last two decades,laparoscopic liver surgery has emerged as an option at major academic institutions.The purpose of this study is to describe the initial experience of minimally invasive liver resections at a non-academic institution. METHODS:We retrospectively reviewed medical records of patients undergoing laparoscopic liver resections between June 2006 and December 2009 at our center.Indications, technical aspects,and outcomes of these patients are described. RESULTS:Laparoscopic liver resection was attempted in 28 patients.Of these,27 patients underwent laparoscopic liver resection(22 total laparoscopic and 5 hand assisted)and one needed conversion to open surgery.Twenty patients had a benign lesion and 8 had malignant lesions.Three patients had multiple lesions in different segments requiring separate resections.The lesions were located in segments Ⅱ-Ⅲ(n=18), Ⅳ(n=3),Ⅴ-Ⅵ(n=9),and VII(n=1).Tumor size ranged from 1.5 cm to 8.5 cm.The surgical procedures included left lateral sectionectomy(n=17),left hepatectomy(n=2),sectionectomy (n=8),and local resections(n=4).Median operative time was 110 minutes(range 55-210 minutes),and the median length of hospital stay was 2.5 days(range 1-7 days).There was no perioperative mortality.One patient developed hernia at the site of tumor extraction requiring repair at 3 months. CONCLUSIONS:Laparoscopic liver resections can be safely performed in selected patients with benign and malignant liver tumors.With increasing experience,laparoscopic liver resections are likely to become a favorable alternative to open resection. | Ashish Singhal Vivek Kohli Nazih | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，1： | 7 |
| 4 | 低VOC涂料用成膜助剂(英文)显示文摘随着环保法规的日益严格和人们环境质量意识的增强,研发新型材料,采用新工艺是降低VOC的有效途径。本文介绍了新型油酸类无溶剂型成膜助剂,能有效降低涂料中的VOC含量以及提高涂料相应性能。 | Shruti Singhal | 2006 | 涂料工业2006，36，9： | 5 |
| 5 | Imaging of the temporomandibular joint: An update显示文摘Imaging of the temporomandibular joint(TMJ) is continuously evolving with advancement of imaging technologies. Many different imaging modalities are currently used to evaluate the TMJ. Magnetic resonance imaging is commonly used for evaluation of the TMJ due to its superior contrast resolution and its ability to acquire dynamic imaging for demonstration of the functionality of the joint. Computed tomography and ultrasound imaging have specific indication in imaging of the TMJ. This article focuses on state of the art imaging of the temporomandibular joint. Relevant normal anatomy and biomechanics of movement of the TMJ are discussed for better understanding of many TMJ pathologies. Imaging of internal derangements is discussed in detail. Different arthropathies and commontumors are also discussed in this article. | Asim K Bag Santhosh Gaddikeri Aparna Singhal Simms Hardin Benson D Tran Josue A Medina Joel K Curé | 2014 | World Journal of Radiology2014，6，8： | 5 |
| 6 | Giant cell tumor of the pancreas:a pathological diagnosis with poor prognosis显示文摘BACKGROUND: Giant cell tumors are rare and highly malignant tumors of the pancreas. Based on two distinct cell populations, they have been divided into two subtypes corresponding to the osteoclast-like giant cell tumor and the pleomorphic giant cell carcinoma of the pancreas. Distinctive imaging features of the tumors remain uncharacterized. Surgical removal is the only appropriate treatment for them, but responses to chemotherapy or radiotherapy remain undocumented. METHODS: Clinical, radiological, histopathologic, and immuno- histochemical features of two cases of giant cell tumor of the pancreas are presented along with a brief review of the literature. RESULTS: En-bloc resection was done successfully in both cases. The patient with an osteoclast-like giant cell tumor remained disease-free with no clinical or radiological evidence of recurrence at 6 months after surgery. However, the patient with the pleomorphic type died 4 months later due to diffuse pulmonary metastasis. CONCLUSIONS: En-bloc surgical resection is the only appropriate treatment for giant cell tumors. The overall prognosis of these tumors is poorer than that of pancreatic ductal adenocarcinoma, especially the pleomorphic type. More studies are required to document the management and outcomes of the tumors. | Ashish Singhal Stan S Shrago Vivek Kohli | 2010 | Hepatobiliary & Pancreatic Diseases International2010，9，4： | 4 |
| 7 | Traumatic cardiac injury: Experience from a level-1 trauma centre显示文摘 | Biplab Mishra Amit Gupta Sushma Sagar Maneesh Singhal Subodh Kumar | 2016 | Chinese Journal of Traumatology2016，19，6： | 4 |
| 8 | 在有经历非肝的外科的肝疾病的病人的 Perioperative 风险因素显示文摘 The patients with liver disease present for various surgical interventions. Surgery may lead to complications in a significant proportion of these patients. These complications may result in considerable morbidity and mortality. Preoperative assessment can predict survival to some extent in patients with liver disease undergoing surgical procedures. A review of literature suggests nature and the type of surgery in these patients determines the peri-operative morbidity and mortality. Optimization of premorbid factors may help to reduce perioperative mortality and morbidity. The purpose of this review is to discuss the effect of liver disease on perioperative outcome; to understand various risk scoring systems and their prognostic significance; to delineate different preoperative variables implicated in postoperative complications and morbidity; to establish the effect of nature and type of surgery on postoperative outcome in patients with liver disease and to discuss optimal anaesthesia strategy in patients with liver disease. | Chandra Kant Pandey Sunaina Tejpal Karna Vijay Kant Pandey Manish Tandon Amit Singhal Vivek Mangla | 2012 | World Journal of Gastrointestinal Surgery2012，4，12： | 4 |
| 9 | Countermeasures for local scour at offshore wind turbine monopile foundations:A review显示文摘Local scour at monopile foundations of offshore wind turbines is one of the most critical structural stability issues.This article reviews the contemporary methods of scour countermeasures at monopile foundations.These methods include armouring countermeasures(e.g.,riprap protection)to enhance the anti-scour ability of the bed materials and flow-altering countermeasures(e.g.,collars and sacrificial piles)to reduce downflow or change flow patterns around the monopiles.Stability number and size-selection equations for riprap armour layers are summarised and compared.Moreover,other alternative methods to riprap are briefly introduced and presented.A typical graph of the scour depth reduction with different collar sizes and elevations under specific test conditions is summarised and compared with a plot for a pile founded on a caisson.Reduction rates for different flow-altering countermeasures,including the collar,are listed and compared.A newly developed soil improvement method,namely microbially induced calcite precipitation(MICP),is also reviewed and introduced as a scour protection method.As a popular bio-soil treatment method,MICP has a good potential as a scour countermeasure method.Bio-soil treatment methods and traditional armouring methods are defined as active and passive soil enhancement scour countermeasures,respectively. | Zi-hao Tang Bruce Melville Naresh Singhal Asaad Shamseldin Jin-hai Zheng Da-wei Guan Liang Cheng | 2022 | Water Science and Engineering2022，15，1： | 4 |
| 10 | Effect of doping of different rare earth(europium,gadolinium,dysprosium and neodymium) metal ions on structural,optical and photocatalytic properties of LaFeO3 perovskites显示文摘Different rare earth substituted perovskites LaRExFe1-xO3(where RE=Eu3+,Gd3+,Dy3+,Nd3+and x=0.02,0.04,0.06,0.08,0.1)with orthorhombic structure and narrow band gaps were successfully fabricated via sol-gel autocombustion method.All the substituted perovskites are found to exhibit excellent photocatalytic activity towards the oxidative degradation of dye molecules.An excellent increase in the rate constant values of pure perovskite(LaFeO3)photocatalytic reactions is observed with the substitution of rare earth metal ions.Best results are obtained for LaNd0.1Fe0.9O3 which exhibits around 7 times increase in the rate constant values for degradation reaction of SO(1.76×10-1 min-1)and RBY(1.69×10-1 min-1)dyes. | Manisha Dhiman Sonal Singhal | 2019 | Journal of Rare Earths2019，37，12： | 4 |
| 11 | Endoscopic full thickness resection for gastric tumors originating from muscularis propria显示文摘AIM: To do systematic review of current literature for endoscopic full thickness resection(EFTR) technique for gastric tumors originating from muscularis propria.METHODS: An extensive English literature search was done till December 2015; using Pub Med and Google scholar to identify the peer reviewed original and review articles using keywords-EFTR, gastric tumor, muscularis propria. Human only studies were included. The references of pertinent studies were manually searched to identify additional relevant studies. The indications, procedural details, success rates, clinical outcomes, complications and limitations were considered. For the purpose of review, data from individual studies was combined to calculate mean. No other statistical test was applied.RESULTS: A total of 9 original articles were identified. Four articles were from same institute and the time frames of these studies were overlapping. To avoid duplication of data, only the study with patients over the longest time interval was included and other three were excluded. In total six studies were included in the final review. In our systematic review, the mean success rate for EFTR of gastric tumors originating from muscularis propria was 96.8%. The mean procedure time varied from a minimum of 37 min to a maximum of 105 min. There was no reported mortality from the technique itself. The most common histological diagnosis was gastrointestinal stromal tumors and leiomyoma. Gastric wall defect closure by either metallic clips or over the scope clip(OTSC) had similar outcomes although experience with OTSC was limited to smaller lesions(<3cm).CONCLUSION: EFTR is a minimally invasive technique to resect gastric submucosal tumors originating from muscularis propria with a high success rate and low complication rate. | Deepanshu Jain Ejaz Mahmood Aakash Desai Shashideep Singhal | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，14： | 4 |
| 12 | Importance of reporting segmental bowel preparation scores during colonoscopy in clinical practice显示文摘AIM: To evaluate the impact of reporting bowel preparation using Boston Bowel Preparation Scale(BBPS) in clinical practice.METHODS: The study was a prospective observational cohort study which enrolled subjects reporting for screening colonoscopy. All subjects received a gallon of polyethylene glycol as bowel preparation regimen. After colonoscopy the endoscopists determined quality of bowel preparation using BBPS. Segmental scores were combined to calculate composite BBPS. Site and size of the polyps detected was recorded. Pathology reports were reviewed to determine advanced adenoma detection rates(AADR). Segmental AADR's were calculated and categorized based on the segmental BBPS to determine the differential impact of bowel prep on AADR. RESULTS: Three hundred and sixty subjects were enrolled in the study with a mean age of 59.2 years, 36.3% males and 63.8% females. Four subjects with incomplete colonoscopy due BBPS of 0 in any segment were excluded. Based on composite BBPS subjects were divided into 3 groups; Group-0(poor bowel prep, BBPS 0-3) n = 26(7.3%), Group-1(Suboptimal bowel prep, BBPS 4-6) n = 121(34%) and Group-2(Adequate bowel prep, BBPS 7-9) n = 209(58.7%). AADR showed a linear trend through Group-1 to 3; with an AADR of 3.8%, 14.8% and 16.7% respectively. Also seen was a linear increasing trend in segmental AADR with improvement in segmental BBPS. There was statistical significant difference between AADR among Group 0 and 2(3.8% vs 16.7%, P < 0.05), Group 1 and 2(14.8% vs 16.7%, P < 0.05) and Group 0 and 1(3.8% vs 14.8%, P < 0.05). χ2 method was used to compute P value for determining statistical significance.CONCLUSION: Segmental AADRs correlate with segmental BBPS. It is thus valuable to report segmental BBPS in colonoscopy reports in clinical practice. | Deepanshu Jain Mojdeh Momeni Mahesh Krishnaiah Sury Anand Shashideep Singhal | 2015 | World Journal of Gastroenterology2015，21，13： | 4 |
| 13 | Advances in solid oxide fuel cell technology显示文摘 | S.C Singhal | 2000 | Solid State Ionics2000，，1： | 3 |
| 14 | Association of overexpression of TIF1γ with colorectal carcinogenesis and advanced colorectal adenocarcinoma显示文摘AIM:To determine the expression and clinical significance of transcriptional intermediary factor 1 gamma (TIF1γ),Smad4 and transforming growth factor-beta (TGFβR) across a spectrum representing colorectal cancer (CRC) development.METHODS:Tissue microarrays were prepared from archival paraffin embedded tissue,including 51 colorectal carcinomas,25 tubular adenomas (TA) and 26 HPs,each with matched normal colonic epithelium.Immunohistochemistry was performed using antibodies against TIF1γ,Smad4 and TGFβ RⅡ.The levels of expression were scored semi-quantitatively (score 0-3 or loss and retention for Smad4).RESULTS:Overexpression of TIF1γ was detected in 5/26 (19%) HP;however,it was seen in a significantly higher proportion of neoplasms,15/25 (60%) TAs and 24/51 (47%) CRCs (P<0.05).Normal colonic mucosa,HP,and TAs showed strong Smad4 expression,while its expression was absent in 22/51 (43%) CRCs.Over-expression of TGFβ RⅡ was more commonly seen in neoplasms,13/25 (52%) TAs and 29/51 (57%) CRCs compared to 9/26 (35%) HP (P<0.05).Furthermore,there was a correlation between TIF1γ overexpression and Smad4 loss in CRC (Kendall tau rank correlation value=0.35,P<0.05).The levels of TIF1γ overexpression were significantly higher in stage Ⅲ than in stage Ⅰ and Ⅱ CRC (P<0.05).CONCLUSION:The findings suggest that over-expression of TIF1γ occurs in early stages of colorectal carcinogenesis,is inversely related with Smad4 loss,and may be a prognostic indicator for poor outcome. | Shilpa Jain Shashideep Singhal Franto Francis Cristina Hajdu Jin-Hua Wang Arief Suriawinata Yin-Quan wang Miao Zhang Elizabeth H Weinshel Fritz Francois Zhi-Heng Pei Peng Lee Ru-Liang Xu | 2011 | World Journal of Gastroenterology2011，17，35： | 3 |
| 15 | myocardial 以后梗塞巨人让室的 pseudoaneurysm 与严重的心失败介绍显示文摘 Left ventricle(LV) pseudoaneurysm is a late mechanical complication of myocardial infarction.A giant LV pseudoaneurysm is a rare presentation.We report a case of giant LV pseudoaneurysm in a post-MI patient who presented with gross congestive heart failure.The patient had a successful surgical repair of the aneurysm and had a favorable 3-mo outcome.The imaging modality and surgical treatment of the pseudoaneurysm are discussed. | Rajesh Vijayvergiya Alok Kumar Sandeep S Rana Harkant Singh Goverdhan D Puri Manphool Singhal | 2012 | World Journal of Cardiology2012，4，11： | 3 |
| 16 | Nrf2 is required for normal postnatal bone acquisition in mice显示文摘A large body of literature suggests that bone metabolism is susceptible to the ill effects of reactive species that accumulate in the body and cause cellular dysfunction. One of the body's front lines in defense against such damage is the transcription factor, Nrf2. This transcription factor regulates a plethora of antioxidant and cellular defense pathways to protect cells from such damage. Despite the breadth of knowledge of both the function of Nrf2 and the effects of reactive species in bone metabolism, the direct role of Nrf2 in skeletal biology has yet to be thoroughly examined. Thus, in the current study, we have examined the role of Nrf2 in postnatal bone metabolism in mice. Mice lacking Nrf2(Nrf22/2) exhibited a marked deficit in postnatal bone acquisition,which was most severe at 3 weeks of age when osteoblast numbers were 12-fold less than observed in control animals. While primary osteoblasts from Nrf22/2mice functioned normally in vitro, the colony forming capacity of bone marrow stromal cells(BMSCs) from these mice was significantly reduced compared to controls.This defect could be rescued through treatment with the radical scavenger N-acetyl cysteine(NAC), suggesting that increased reactive species stress might impair early osteoblastogenesis in BMSCs and lead to the failure of bone acquisition observed in Nrf22/2animals. Taken together, these studies suggest Nrf2 represents a key pathway in regulating bone metabolism, which may provide future therapeutic targets to treat osteoporosis. | Jung-Hyun Kim Vandana Singhal Shyam Biswal Rajesh K Thimmulappa Douglas J Di Girolamo | 2014 | Bone Research2014，2，4： | 3 |
| 17 | Novel anti-diabetic agents in non-alcoholic fatty liver disease: a mini-review显示文摘BACKGROUND:Non-alcoholic fatty liver disease(NAFLD)encompasses a spectrum that ranges from simple steatosis to non-alcoholic steatohepatitis(NASH)and to cirrhosis.The recommended treatment for this disease includes measures that target obesity and insulin resistance.The present review summarizes the role of newer anti-diabetic agents in treatment of NAFLD.DATA SOURCES:PubMed,MEDLINE and Ovid databases were searched to identify human studies between January 1990and January 2013 using specified key words.Original studies that enrolled patients with a diagnosis of NAFLD or NASH and involved use of newer classes of anti-diabetic agents for a duration of at least 3 months were included.RESULTS:Out of the screened articles,four met eligibility criteria and were included in our review.The classes of newer anti-diabetic medications described were dipeptidyl peptidase IV inhibitors and glucagon-like peptide-1 analogues.CONCLUSIONS:Liraglutide and Exenatide showed improvement in transaminases as well as histology in patients with NASH.Sitagliptin showed improvement in transaminases but limited studies are there to access its effect on histology.Further studies are needed to support use of newer anti-diabetic medications in patients with NAFLD. | Manhal Olaywi Taruna Bhatia Sury Anand Shashideep Singhal | 2013 | Hepatobiliary & Pancreatic Diseases International2013，12，6： | 3 |
| 18 | Peroral endoscopic reduction of dilated gastrojejunal anastomosis after bariatric surgery: Techniques and efficacy显示文摘AIM: To investigate the techniques and efficacy of peroral endoscopic reduction of dilated gastrojejunal anastomosis after bariatric surgery.METHODS: An extensive English language literature search was conducted using Pub Med, MEDLINE, Medscape and Google to identify peer-reviewed original and review articles using the keywords 'bariatric endoscopic suturing', 'overstitch bariatric surgery', 'endoscopic anastomotic reduction', 'bariatric surgery', 'gastric bypass', 'obesity', 'weight loss'. We identified articles describing technical feasibility, safety, efficacy, and adverse outcomes of overstitch endoscopic suturing system for transoral outlet reduction in patients with weight regain following Roux-en-Y gastric bypass(RYGB). All studies that contained material applicable to the topic were considered. Retrieved peer-reviewed original and review articles were reviewed by the authors and the data extracted using a standardized collection tool. Data were analyzed using statistical analysis as percentages of the event. RESULTS: Four original published articles which met our search criteria were pooled. The total number cases were fifty-nine with a mean age of 46.75 years(34-63 years). Eight of the patients included in those studies were males(13.6%) and fifty-one were females(86.4%). The mean time elapsed since the primary bypass surgery was 5.75 years. The average pre-endoscopic procedure body mass index(BMI) was 38.68(27.5-48.5). Mean body weight regained post-RYGB surgery was 13.4 kg from their post-RYGB nadir. The average pouch length at the initial upper endoscopy was 5.75 cm(2-14 cm). The pre-intervention anastomotic diameter was averaged at 24.85 mm(8-40 mm). Average procedure time was 74 min(50-164 min). Mean post endoscopic intervention anastomotic diameter was 8 mm(3-15 mm). Weight reduction at 3 to 4 mo post revision noted to be anaverage of 10.1 kg. Average overall post revision BMI was recorded at 37.7. The combined technical and clinical success rate was 94.9%(56/59) among studied participants. CONCLUSION: Endoscopic suturing can be technically feasible, effective and safe for transoral outlet reduction in patients with weight regain following RYGB. | Kinesh Changela Emmanuel Ofori Sushil Duddempudi Sury Anand Shashideep Singhal | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，4： | 2 |
| 19 | Coexistence of pneumothorax and chilaiditi sign:A case report显示文摘We present a case of 50 year old male patient with coexistence of Pneumothorax and Chilaiditi sign.Chilaiditi sign is an incidental radiographic finding of a usually asymptomatic condition in which a part of intestine is located between the liver and diaphragm;however,the term'Chilaiditi syndrome'is used for symptomatic hepatodiaphragmatic interposition.The patient had no symptoms of abdominal pain,constipation,diarrhea,or emesis.Incidentally,Chilaiditi sign was diagnosed on chest radiography.Pneumothorax is defined as air in the pleural space.Pneumothoraces are classified as spontaneous or traumatic.Spontaneous pneumothorax is labelled as primary when no underlying lung disease is present,or secondary,when it is associated with pre-existing lung disease.Our case is the rare in the literature indicating the coexistence of Chilaiditi sign and pneumothorax. | Tangri Nitin Singhal Sameer Sharma Priyanka Mehta Dinesh Bansal Sachin Bhushan Neeraj Singla Sulbha Singh Puneet | 2014 | Asian Pacific Journal of Tropical Biomedicine2014，4，1： | 2 |
| 20 | Over the Scope Clip: Technique and Expanding Clinical Applications显示文摘 | Shashideep Singhal Kinesh Changela Haris Papafragkakis Sury Anand Mahesh Krishnaiah Sushil Duddempudi | 2013 | Journal of Clinical Gastroenterology2013，，9： | 2 |
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