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| 1 | Metastatic type 1 gastric carcinoid:A real threat or just a myth?显示文摘AIM:To describe disease characteristics and treatment modalities in a group of rare patients with metastatic gastric carcinoid type 1(GCA1).METHODS:Information on clinical,biochemical,radiological,histopathological findings,the extent of the disease,as well as the use of different therapeutic modalities and the long-term outcome were recorded.Patients’data were assessed at presentation,and thereafter at 6 to 12 monthly intervals both clinically and biochemically,but also endoscopically and histopathologically.Patients were evaluated for the presence of specific symptoms;the presence of autoimmune disorders and the presence of other gastrointestinal malignancies in other family members were also recorded.The evaluation of response to treatment was defined using established WHO criteria.RESULTS:We studied twenty consecutive patients with a mean age of 55.1 years.The mean follow-up period was 83 mo.Twelve patients had regional lymph node metastases and 8 patients had liver metastases.The primary tumor mean diameter was 20.13±10.83mm(mean±SD).The mean Ki-67 index was 6.8%±11.2%.All but one patient underwent endoscopic or surgical excision of the tumor.The disease was stable in all but 3 patients who had progressive liver disease.All patients remained alive during the follow-up period.CONCLUSION:Metastatic GCA1 carries a good overall prognosis,being related to a tumor size of≥1 cm,an elevated Ki-67 index and high serum gastrin levels. | Simona Grozinsky-Glasberg Dimitrios Thomas Jonathan R Strosberg Ulrich-Frank Pape Stephan Felder Apostolos V Tsolakis Krystallenia I Alexandraki Merav Fraenkel Leonard Saiegh Petachia Reissman Gregory Kaltsas David J Gross | 2013 | World Journal of Gastroenterology2013，19，46： | 11 |
| 2 | Final height in girls with central idiopathic precocious puberty treated with gonadotropin-releasing hormone analog and oxandrolone 显示文摘 | Alessandra V Simona P Marta V | 2006 | J Clin Endoerinol Etab2006，91，4： | 1 |
| 3 | Biofunctionalization of textile materials by antimicrobial treatments : A crit- ical overview 显示文摘 | Diana C Simona O Narcisa V | 2010 | Rom Biotech Lett2010，15，1： | 1 |
| 4 | HPLC fingerprint of bioactive compounds and antioxidant activities of Viscum album from differ-ent host trees显示文摘 | SIMONA I V DUMITRIA RA LOREDANA L | 2011 | Not Bot Hort Agrobot Cluj2011，39，1： | 1 |
| 5 | Molecular characterization of lymphatic endothelial cells 显示文摘 | Simona P Pascal B Paula V | 2002 | PNAS2002，99，16： | 1 |
| 6 | Human papilloma virus DNA testing by PCR - ELISA and hybrid capture Ⅱ from a single cytological specimen: concordance and correlation with cytological results 显示文摘 | SIMONA V MONICA C FRANCESCA B | 2002 | Journal of Clinical Viology2002，32，25： | 1 |
| 7 | Role of C - reactive protein in contributing to increased cardiovascular risk in metabolic syndrome显示文摘 | Sridevi D Simona V Devid S | 2010 | Curr Atheroscler Rep2010，12，2： | 1 |
| 8 | Analysis of genetic diversity of Furcellaria lumbricalis (Gigartinales, Rhodophyta) in the Baltic Sea by RAPD-PCR technique 显示文摘 | Simonas V Antta M Tapani Y M | 2000 | Phycologia2000，39，2： | 1 |
| 9 | Final height in girls with central idiopathic precocious puberty treated with gonadotropin-releasing hormone analog and oxandrolone显示文摘 | Alessandra V Simona P Marta V | 2006 | J Clin Endocrinol Metab2006，91，4： | 1 |
| 10 | Polymorphisms in arsenic (+III)methyltransferase (AS3MT) predict gene expression of AS3MT as wellas arsenic metabolism显示文摘 | KarinE Marie V Simona JM | 2011 | Environ Health Perspect2011，119，： | 1 |
| 11 | Panayiotopoulos syndrome: a clinical, EEG and neuropsychological study of 93 consecutive patients显示文摘 | Nicola S Marina T Vincenzo DC Simona C Giovanni M Josiv V | 2010 | Epilepsia2010，51，10： | 1 |
| 12 | Effect of a tomato-based drink on markers of inflammation, immunomodulation, and oxida- tive stress 显示文摘 | Patrizia R Francesco V Simona G | 2006 | J Agric Food Chem2006，54，7： | 1 |
| 13 | Modeling Trust to Study Consumers' Acceptance of Online Shopping显示文摘 | SIMONA V IULIANA C LUIGI D ALIN O | 2013 | Revista Economica2013，，65： | 1 |
| 14 | Biochemical basis for retinol deficiency induced by the 141N and G75D mutations in human plasma retinol-binding protein 显示文摘 | Claudia F Simona V Marco B | 2005 | Biochemical and Biophysical Research Communications2005，336，： | 1 |
| 15 | Human papillomavirus DNA testing by PCR-ELISA and hybrid capture Ⅱ from a single cytological specimen:concordance and correlation with cytological results显示文摘 | Simona V Monica C Francesca B | 2002 | Journal of Clinical Viology2002，32，25： | 1 |
| 16 | Suitability of soil microbial parameters as indicators of heavy metal pollution显示文摘 | Simona C Angela R F Amalia V D S | 2004 | Water Air and Soil Pollution2004，158，1： | 1 |
| 17 | Dgrivative Potentiometric Stripping Analysis (dPSA) Used forthe Determination of Cadmium,Copper,Lead and Zinc in Sicilian Olive Oils显示文摘 | Lara L Simona L Alessandro V | | 0，，11： | 1 |
| 18 | Pain and oxidative stress in the newborn显示文摘 | iLorenzo I Carlo V B Simona N | 2010 | Early Hum Dev2010，86，1： | 1 |
| 19 | Role of C-reactive protein incontributing to increased cardiovascular risk in metabolic syndrome显示文摘 | Sridevi D Simona V Devid St | 2010 | Curr Atheroscler Rep2010，12，2： | 1 |
| 20 | Molecular characteriza- tion of lymphatic endothelial cells 显示文摘 | Simona P Pascal B Paula V | 2002 | PNAS2002，99，25： | 1 |
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