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| 1 | Cancer risk in patients with hereditary hemochromatosis and in their first-degree relatives显示文摘 | Maria Elmberg Rolf Hultcrantz Anders Ekbom Lena Brandt Sigvard Olsson Rolf Olsson Stefan Lindgren Lars L??f Per St?l Sven Wallerstedt Sven Almer Hanna Sandberg-Gertzén Johan Askling | 2003 | Gastroenterology2003，，6： | 1 |
| 2 | Multiplex real-time PCR for detection of respiratory tract infections显示文摘 | Robin Brittain-Long Sandra Nord Sigvard Olofsson Johan Westin Lars-Magnus Anderson Magnus Lindh | 2007 | Journal of Clinical Virology2007，，1： | 1 |
| 3 | Detection and Typing of herpes simplex virus(HSV) in mucocutaneous samples by TaqMan PCR targeting a gB segment homologous for HSV types 1 and 2显示文摘 | Lilly Namvar Sigvard Olofsson Tomas Bergstrom | 2005 | Journal of Clinical Microbiology2005，5，： | 1 |
| 4 | Hemorrhagic colitis induced by trientine in a 51-year-old patient with Wilson's disease waiting for liver transplantation:A case report显示文摘BACKGROUND Wilson's disease(WD)is a rare inherited disorder of copper metabolism.Treatment consists of chelating agents,but side effects are common.We describe a patient who developed colitis during trientine treatment leading to decompensation of liver cirrhosis.CASE SUMMARY A healthy 51-year-old woman was diagnosed with liver cirrhosis due to decompensation with ascites.Etiologic evaluation raised suspicion of hereditary hemochromatosis because of compound heterozygosity HFE p.C282Y/p.H63D,and phlebotomy was started.Re-evaluation showed low ceruloplasmin,increased urinary copper excretion and the presence of Kayser-Fleischer rings.WD was confirmed by genetic analysis.Because of decompensated cirrhosis,she was referred for liver transplant evaluation.Simultaneously,treatment with trientine was initiated.Liver function initially stabilized,and the patient was not accepted for a liver transplant.Shortly after this,she developed severe hemorrhagic colitis,most probably a side effect of trientine.During that episode,she decompensated with hepatic encephalopathy.Because of a second decompensating event,she was accepted for liver transplantation,and an uneventful transplantation was carried out after clinical improvement of colitis.CONCLUSION Despite WD being a rare disorder,it is important to consider because it can present with a plethora of symptoms from childhood to an elderly age.Colitis should be recognized as a serious adverse drug reaction to trientine treatment that can result in decompensated liver disease. | Andreas Schult Matts Andersson Jorge Asin-Cayuela Karl Sigvard Olsson | 2022 | World Journal of Hepatology2022，14，8： | 1 |
| 5 | Ropivacaine for dental anesthesia: a dose-finding study 显示文摘 | Malin E Sigvard K | 2002 | J Oral Maxillofae Surg2002，60，9： | 1 |
| 6 | Ropivacaine for dental anesthesia: a dose-finding study 显示文摘 | Malin E Sigvard K | 2002 | J Oral Maxillofac Surg2002，60，9： | 1 |
| 7 | Objective Criteria Accurately Predict Amputation following Lower Extremity Trauma显示文摘 | KAJ JOHANSEN MICHAEL DAINES THOMAS HOWEY DAVID HELFET SIGVARD T. HANSEN | 1990 | The Journal of Trauma: Injury, Infection, and Critical Care1990，，5： | 1 |
| 8 | Seasonal variations of 15 respiratory agents illustrated by the application of a multiplex polymerase chain reaction assay显示文摘 | Robin Brittain-Long Lars-Magnus Andersson Sigvard Olofsson Magnus Lindh Johan Westin | 2012 | Scandinavian Journal of Infectious Diseases2012，，1： | 1 |
| 9 | Can a multifaceted educational intervention targeting both nurses and physicians change the prescribing of antibiotics to nursing home residents a cluster randomized controlled trial 显示文摘 | Eva P Asa V Sigvard M | 2011 | J Antimicrob Chemother2011，66，： | 1 |
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