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45篇 您的检索式:作者名="SHASHI A"
    题名 作者 年代 出处 被引量
1IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice显示文摘Petrasek Jan Bala Shashi Csak Timea Lippai Dora Kodys Karen Menashy Victoria Barrieau Matthew Min So-Yun Kurt-Jones Evelyn A Szabo Gyongyi 2012EN2012,,10:4
2Changes in glycogen content in some tissues during fluorosis : An experimental study on rabbits显示文摘Shashi A 1988Fluoride1988,21,1:1
3Pathologic alterations in endocrine pancreatic islet cells during experimental flruoosis 显示文摘SHASHI A SHARMA N BHARDWAJ M 2007Asian J Microbiol Biotechnol Environ Sci2007,9,4:1
4Histopathological investigation of fluoride induced neu- rotoxicity in rabbits显示文摘Shashi A 2003Fluoride2003,36,2:1
5Toxic effects of fluoride on rabbit kidney显示文摘Shashi A Singh JP Thapar SP 2002Fluoride2002,35,1:1
6Nucleic acid levels in thyroid gland in acute and chronic fluoride intoxication显示文摘Shashi A 1993Fluoride1993,26,3:1
7Preliminary observations on alterations in rabbit ovary DNA and RNA content in experimental fluorosis 显示文摘Shashi A 1994Fluoride1994,27,2:1
8Nitric oxide alleviates oxidative damage induced by high temperature stress in wheat显示文摘Bavita A Shashi B Navtej SB 2012Indian Journal of Experimental Biology2012,50,5:1
9Histochemical pattern of gastrocnemius muscle in fluoride toxicity syndrome显示文摘Objective:To evaluate the effect of sodium fluoride(NaF) on cytochemical distribution of proteins,DNA,and RNA in the gastrocnemius muscle of rat in experimental fluorosis.Methods: Young Sprague Dawley albino rats were administered with NaF at 30,45,and 75 mg/kg bw/ day subcutaneously for 15 and 30 days,respectively.The control animals were given the vehicle(1cc deionized double distilled water/kg bw/day).Results:In the first phase of 15 days experimentation,the gastrocnemius muscle of rats intoxicated with NaF at 30,45,and 75 mg /kg bw/ day showed decline in proteins including a amino acids as compared to control. In the second phase of 30 days experimentation,the muscle fibers of rat showed elevation in sarcolemmal and sarcoplasmic proteins in 30 mg NaF dose group,and angulated fibers exhibited increase in sarcolemmal proteins in 45 mg NaF group.The marginal regions of angular and rim fibers showed deeply stained rings of sarcoplasmic proteins whereas the split fibers were faindy stained in rats treated with NaF at 75 mg/kg bw/day for 30 days.In rats treated with NaF at 30 mg/kg bw/day for 15 days,the hypertrophied peripheral muscle fibers contained more DNA,however the atrophied fibers had more RNA.In 45 mg NaF group,RNA was located in sarcolemmal regions,while DNA content decreased as compared to control.In 75 mg NaF group,the muscle fibers had dark and light staining regions of DNA and RNA.In the 30 days of experimentation,the DNA level decreased whereas RNA content increased in the gastrocnemius muscle fibers of the rat treated with NaF at 30 mg/kg bw/day.In treatment group with NaF at 45 mg/kg bw/day,the RNA content slighdy declined in comparison to control,in all treatments for 15 days as well as in treatment group with NaF at 30 mg/kg bw/day for 30 days whereas the amount of DNA slightly increased as compared to treatment group with NaF at 75 mg/kg bw/day for 15 days.The highest dose group revealed elevated amount of RNA whereas DNA content remained stable.Conclusions:The findings of present study demonstrate that certain concentrations of fluoride can induce muscle lesions and damage DNA,RNA,and protein in muscle cells and excessive intake and accumulation of fluoride is therefore a serious risk factor for muscular abnormalities in fluorosis.Shashi A Bhushan B Bhardwaj M 2010Asian Pacific Journal of Tropical Medicine2010,3,2:1
10Effect of long-term administration of fluoride on levels of protein, free amino acids and RNA in rabbit brain 显示文摘Shashi A Singh J P Thapar S P 1978Fluoride1978,11,3:1
11Incidence of skeletal deformities in endemic fluorosis 显示文摘SHASHI A KUMAR M BHARDWAJ M 2008Trop Doct2008,58,4:1
12Hitopatholojical effects of sodium fluoride on the duodenum of rabbits显示文摘SHASHI A 2002Fluoride2002,35,:1
13Changes in glycogen content in some tissues during fluorosis: An experimental study on rabbits 显示文摘Shashi A 1988Fluoride1988,21,1:1
14Histopathological investigation of fluoride in- duced neurotoxicity in rabbits显示文摘Shashi A Patiala G 2003Fluoride2003,36,2:1
15Toxical effects of fluoride on rabbit kidney显示文摘Shashi A Singh JP Thapar SP 2002Fluoride2002,35,1:1
16Structure and dielectric studies of some perovskite - type titanates 显示文摘Varaprased A M Shashi Mohan A L Chakrabarty D K et al 1979Phys C : Solid State Phys1979,12,3:1
17Use of the pro-seal laryngeal mask airway facilitates percutaneous dilatational tracheostomy in an intensive care unit 显示文摘Sarkar S Shashi P Paswan A 2010Indian J flit Care Med2010,14,4:1
18Pseudometabolic presentation of dystrophinopathy due to a missense mutation 显示文摘Veerapandiyan A Shashi V Jiang Y H 2010Muscle Nerve2010,42,6:1
19Incidence of skeletal deformities in endemic fluorosis显示文摘Shashi A Kumar M Bhardwaj M 0,,04:1
20Effect of long--term adminiotration of fluoride on levels of pratein, free amino acds and RND in rabbit brain显示文摘Shashi A 1994Fluoride1994,27,3:1
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