|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 纳米复合佐剂的抗肿瘤免疫调控作用及效果研究显示文摘目的:探究纳米复合佐剂在肿瘤内的免疫调控作用及抗肿瘤效果。方法:制备包载CpG的β葡聚糖纳米颗粒(CNP),体外培养小鼠骨髓来源的树突细胞(BMDC),分5组进行体外免疫处理,分别为PBS对照组、β葡聚糖组、β葡聚糖纳米载体(NP)组、CpG组和CNP组,利用流式仪分析BMDC成熟情况。将体外培养的黑色素瘤B16F10细胞接种于C57BL/6N小鼠右后肢皮下,建立肿瘤模型,第6 d挑选肿瘤大小相对一致的24只小鼠均分为4组,即PBS组、NP组、CpG组、CNP组进行治疗,后颈部皮下注射给药,共给药4次,每次间隔3 d,期间隔天测量肿瘤体积,最后一次给药后第3 d眼眶取血,测定血浆中γ干扰素(IFN-γ)浓度,处死小鼠后分离肿瘤及脾脏,流式细胞术检测瘤内浸润性T淋巴细胞比例及脾脏内T细胞比例。结果:CNP佐剂处理后BMDC成熟比例约为CpG佐剂组的2.8倍。在小鼠体内接种肿瘤15 d后,CNP治疗组肿瘤体积较其他组均减小,血浆中IFN-γ含量显著高于其他实验组,约为CpG组的1.5倍,肿瘤浸润性T淋巴细胞与其他组相比也有明显升高。结论:构建的葡聚糖-CpG纳米复合佐剂能够有效激活BMDC,改善肿瘤微环境,具有良好的体内抗肿瘤效果。 | 赵佳琦 Khattak Sameena Noor 董晓筱 胡张可 韩卢 邓雄威 安东妮娜 胡秦 盛望 | 2020 | 生物技术通讯2020，31，2： | 3 |
| 2 | Development of Non-enzymatic Cholesterol Electrochemical Sensor Based on Polyindole/Tungsten Carbide Nanocomposite显示文摘Non-enzymatic electrochemical sensor was developed for estimation of low-level cholesterol.Polyindole/tungsten carbide(PIN/WC)nanocomposite was synthesized and used as an electroactive material to develop low-cost modified stainless steel plate electrode(SSPE).Surface morphology of developed electrode was characterized by scanning electron microscopy.Electrochemical behavior of cholesterol was investigated through electron impedance spectroscopy,potentiodynamic polarization and cyclic voltammetry in 1-M KOH electrolytic solution.The quantification of cholesterol was studied by square wave voltammetry and differential pulse voltammetry.The calibration plots between the cholesterol concentration and peak current were in linear relation with limit of detection of 1.23×10^(−6) mol L^(−1).The overall result reveals that developed PIN/WC/SSPE electrode has excellent performance for trace-level cholesterol estimation and can be further employed for cholesterol monitoring in blood serum samples. | Shubham Sharma Preeti Joshi Sameena Mehtab Md.Ghulam Haider Zaidi Kavita Singhal Tanveer Irshad Siddiqi | 2020 | Journal of Analysis and Testing2020，4，1： | 2 |
| 3 | Ants find the shortest path:a mathematical proof显示文摘 | Jayadeva Sameena Shah Amit Bhaya | 2013 | Swarm Intelligence2013，，3： | 1 |
| 4 | Effect of Pterocarpus santalinus bark, on blood glucose, serum lipids, plasma insulin and hepatic carbohydrate metabolic enzymes in streptozotocin-induced diabetic rats显示文摘 | Vinay Kumar Kondeti Kameswara Rao Badri Dilip Rajasekhar Maddirala Sampath Kumar Mekala Thur Shaik Sameena Fatima Ramesh Babu Kasetti Chippada Appa Rao | 2010 | Food and Chemical Toxicology2010，，5： | 1 |
| 5 | Use of Negative Extrathoracic Pressure to Improve Hemodynamics After Cardiac Surgery显示文摘 | Rakesh K. Chaturvedi Arnold A. Zidulka Peter Goldberg Benoit deVarennes Sameena Iqbal Elham Rahme Kevin Lachapelle | 2008 | The Annals of Thoracic Surgery2008，，4： | 1 |
| 6 | Multiplex bead array assays for detection of soluble cytokines : comparisons of sensitivity and quantitative values among kits from multiple manufacturers 显示文摘 | Sameena SK Meghan SS Debra R | 2004 | Clin Cytometry (Part B)2004，61，： | 1 |
| 7 | A cobalt(Ⅱ)-selective PVC membrane based on a Schiff base complex of N,N'-bis(salicylidene)-3,4-diaminotoluene显示文摘 | Gupta Vinod Kumar Singh Ashok Kumar Mehtab Sameena | 2006 | Analytica Chinaica Acta2006，566，1： | 1 |
| 8 | Antihyperglycemic and antihyperlipidemic activities of methanol:water (4:1) fraction isolated from aqueous extract of Syzygium alternifolium seeds in streptozotocin induced diabetic rats显示文摘 | Ramesh Babu Kasetti Maddirala Dilip Rajasekhar Vinay Kumar Kondeti Shaik Sameena Fatima Ethamakula Guravaiah Tiruvenkata Kumar Sirasanagandla Swapna Bellamkonda Ramesh Chippada Appa Rao | 2010 | Food and Chemical Toxicology2010，，4： | 1 |
| 9 | Quartz-titania composites for the photocatalytical modification of construction materi- als显示文摘 | Sameena K Dietmar S | 2013 | Cement & Concrete Composites2013，，36： | 1 |
| 10 | Tremelimumab (anti-CTLA4) mediates immune responses mainly by direct activation of T effector cells rather than by affecting T regulatory cells显示文摘 | Sameena Khan Deborah J. Burt Christy Ralph Fiona C. Thistlethwaite Robert E. Hawkins Eyad Elkord | 2010 | Clinical Immunology2010，，： | 1 |
| 11 | Synthesis ofpseudopolyrotaxanes using mixtures of cyclic oligoesters显示文摘 | Sameena D Philip H Stephen D | 2003 | Reactive& FunetionalPolymers2003，54，： | 1 |
| 12 | Thiocyanate Selective Sensor Based on Tripodal Zinc Complex for DirectDetermination of Thiocyanate in Biological Samples 显示文摘 | Ashok K S Udai P S Sameena M | 2007 | Sens Actuators B2007，125，： | 1 |
| 13 | Cyanoacrylate: a bio adhesive for suture less surgery: a review 显示文摘 | SAMEENA T SETHY SP PATIL P | 2014 | Asian J Res Chem2014，7，3： | 1 |
| 14 | Sol-gel mediated coating and characterization of photocatalytic sand and fumed silica for environmental remediation显示文摘 | Sameena K Dietmar S | 2014 | Water Air Soil ^0^2014，225，： | 1 |
| 15 | Vascular Access–Related Infections: Definitions, Incidence Rates, and Risk Factors显示文摘 | Jean-Philippe Lafrance Elham Rahme Jacques Lelorier Sameena Iqbal | 2008 | American Journal of Kidney Diseases2008，，5： | 1 |
| 16 | Texture,flavor,and sensory quality of buffalo milk Cheddar cheese as influenced by reducing sodium salt content显示文摘 | MURTAZA M A HUMA N SAMEENA | 2014 | Journal of Dairy Science2014，97，11： | 1 |
| 17 | A Novel Action Transformer Network for Hybrid Multimodal Sign Language Recognition显示文摘Sign language fills the communication gap for people with hearing and speaking ailments.It includes both visual modalities,manual gestures consisting of movements of hands,and non-manual gestures incorporating body movements including head,facial expressions,eyes,shoulder shrugging,etc.Previously both gestures have been detected;identifying separately may have better accuracy,butmuch communicational information is lost.Aproper sign language mechanism is needed to detect manual and non-manual gestures to convey the appropriate detailed message to others.Our novel proposed system contributes as Sign LanguageAction Transformer Network(SLATN),localizing hand,body,and facial gestures in video sequences.Here we are expending a Transformer-style structural design as a“base network”to extract features from a spatiotemporal domain.Themodel impulsively learns to track individual persons and their action context inmultiple frames.Furthermore,a“head network”emphasizes hand movement and facial expression simultaneously,which is often crucial to understanding sign language,using its attention mechanism for creating tight bounding boxes around classified gestures.The model’s work is later compared with the traditional identification methods of activity recognition.It not only works faster but achieves better accuracy as well.Themodel achieves overall 82.66%testing accuracy with a very considerable performance of computation with 94.13 Giga-Floating Point Operations per Second(G-FLOPS).Another contribution is a newly created dataset of Pakistan Sign Language forManual and Non-Manual(PkSLMNM)gestures. | Sameena Javaid Safdar Rizvi | 2023 | Computers, Materials & Continua2023，，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员