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| 1 | 肝门部胆管癌手术治疗中血管(特别是肝动脉)切除重建的意义显示文摘方法:回顾性收集从1992年4月到2014年3月横滨市立大学医学院附属医院172例肝门部胆管癌手术病人的影像学资料、手术及预后相关资料。将手术病人是否血管重建分成三组:1.VR(-)组:门静脉、肝动脉都未进行切除(74例)。2.VR-(PV)组:只对门静脉切除重建组(54例)。 | Ryusei Matsuyama Ryutaro Mori Yohei Ota 林杰 刘付宝 | 2016 | 肝胆外科杂志2016，24，5： | 2 |
| 2 | Patient-derived orthotopic xenograft models for cancer of unknown primary precisely distinguish chemotherapy,and tumor-targeting S.typhimurium A1-R is superior to first-line chemotherapy显示文摘Cancer of unknown primary(CUP)is a recalcitrant disease with poor prognosis because it lacks standard first-line therapy.CUP consists of diverse malignancy groups,making personalized precision therapy essential.The present study aimed to identify an effective therapy for a CUP patient using a patient-derived orthotopic xenograft(PDOX)model.This paper reports the usefulness of the PDOX model to precisely identify effective and ineffective chemotherapy and to compare the efficacy of S.typhimurium A1-R with first-line chemotherapy using the CUP PDOX model.The present study is the first to use a CUP PDOX model,which was able to precisely distinguish the chemotherapeutic course.We found that a carboplatinum(CAR)-based regimen was effective for this CUP patient.We also demonstrated that S.typhimurium A1-R was more effective against the CUP tumor than first-line chemotherapy.Our results indicate that S.typhimurium A1-R has clinical potential for CUP,a resistant disease that requires effective therapy. | Kentaro Miyake Tasuku Kiyuna Masuyo Miyake Kei Kawaguchi Sang Nam Yoon Zhiying Zhang Kentaro Igarashi Sahar Razmjooei Sintawat Wangsiricharoen Takashi Murakami Yunfeng Li Scott D.Nelson Tara A.Russell Arun S.Singh Yukihiko Hiroshima Masashi Momiyama Ryusei Matsuyama Takashi Chishima Shree Ram Singh Itaru Endo Fritz C.Eilber Robert M.Hoffman | 2018 | Signal Transduction and Targeted Therapy2018，3，1： | 2 |
| 3 | Increased serum levels of VEGF in patients with renal cell carci-noma显示文摘 | KAZUNARI S NORIHIKO T RYUSEI S | 1999 | Jpan J Cancer Res1999，90，4： | 1 |
| 4 | High-pressure behavior and tribological properties of wind turbine gear oil显示文摘 | Sobahan Mia Shota Mizukami Ryusei Fukuda | 2010 | Journal of Mechanical Science and Technology2010，24，1： | 1 |
| 5 | Immunological Impact of Neoadjuvant Chemoradiotherapy in Patients with Borderline Resectable Pancreatic Ductal Adenocarcinoma显示文摘 | Yuki Homma Koichi Taniguchi Takashi Murakami Kazuya Nakagawa Masatoshi Nakazawa Ryusei Matsuyama Ryutaro Mori Kazuhisa Takeda Michio Ueda Yasushi Ichikawa Kuniya Tanaka Itaru Endo | 2014 | Annals of Surgical Oncology2014，，2： | 1 |
| 6 | Covered self‐expandable metal stent deployment promises safe neoadjuvant chemoradiation therapy in patients with borderline resectable pancreatic head cancer显示文摘 | Kensuke Kubota Takamitsu Sato Seitaro Watanabe Kunihiro Hosono Noritoshi Kobayashi Ryutaro Mori Koichi Taniguchi Ryusei Matsuyama Itaru Endo Atsushi Nakajima | 2014 | Digestive Endoscopy2014，，1： | 1 |
| 7 | Efficacy of neoadjuvant chemotherapy for initially resectable colorectal liver metastases:A retrospective cohort study显示文摘BACKGROUND The liver is the most common metastatic site of colorectal cancer.Hepatectomy is the mainstay of treatment for patients with colorectal liver metastases(CRLMs).However,there are cases of early recurrence after upfront hepatectomy alone.In selected high-risk patients,neoadjuvant chemotherapy(NAC)may improve longterm survival.AIM To determine the efficacy of NAC for initially resectable CRLMs.METHODS Among 644 patients who underwent their first hepatectomy for CRLMs at our institution,297 resectable cases were stratified into an upfront hepatectomy group(238 patients)and a NAC group(59 patients).Poor prognostic factors for upfront hepatectomy were identified using multivariate logistic regression analysis.Propensity score matching was used to compare clinical outcomes between the upfront hepatectomy and NAC groups,according to the number of poor prognostic factors.Survival curves were estimated using the Kaplan-Meier method and compared using the log-rank test.RESULTS Preoperative carcinoembryonic antigen levels(≥10 ng/mL)(P=0.003),primary histological type(other than well/moderately differentiated)(P=0.04),and primary lymph node metastases(≥1)(P=0.04)were identified as independent poor prognostic factors for overall survival(OS)in the upfront hepatectomy group.High-risk status was defined as the presence of two or more risk factors.After propensity score matching,50 patients were matched in each group.Among high-risk patients,the 5-year OS rate was significantly higher in the NAC group(13 patients)than in the upfront hepatectomy group(18 patients)(100%vs 34%;P=0.02).CONCLUSION NAC may improve the prognosis of high-risk patients with resectable CRLMs who have two or more risk factors. | Kazuhisa Takeda Yu Sawada Yasuhiro Yabushita Yuki Honma Takafumi Kumamoto Jun Watanabe Ryusei Matsuyama Chikara Kunisaki Toshihiro Misumi Itaru Endo | 2022 | World Journal of Gastrointestinal Oncology2022，14，7： | 1 |
| 8 | Increased serumlevels of VEGF inp atientsw ith ernalcelc erci-noms显示文摘 | Kazunari S Norihiko T Ryusei S | 1999 | J pm JCancer Res1999，90，4： | 1 |
| 9 | Increased serum levels of VEGF in patients with renal cell carcinoma 显示文摘 | Kazunari S Norihiko T Ryusei S | 1999 | Jpn J Cancer Res1999，90，4： | 1 |
| 10 | Synchronous multiple lung cancers with hilar lymph node metastasis of small cell carcinoma:A case report显示文摘BACKGROUND Synchronous multiple lung cancers are rare and refer to the simultaneous presence of two or more primary lung tumors,which present significant challenges in terms of diagnosis and treatment.CASE SUMMARY We report a case of multiple synchronous lung cancers with hilar lymph node metastasis of small cell carcinoma of unknown origin in a 73-year-old man.Transbronchial lung biopsy revealed squamous cell carcinoma.Although enlargement of lymph node 12u was detected,no distant metastases were observed.The patient was preoperatively diagnosed with T1cN0M0 and underwent thoracoscopic right upper lobectomy with nodal dissection(ND2a).Based on histopathological findings,the primary lesion was squamous cell carcinoma.A microinvasive adenocarcinoma was also observed on the cranial side of the primary lesion.Tumors were detected in two resected lymph nodes(#12u and#11s).Both tumors were pathologically diagnosed as small cell carcinomas.The primary lesion of the small cell carcinoma could not be identified even by whole-body imaging;however,chemotherapy was initiated for hilar lymph node metastasis of the small cell carcinoma of unknown origin.CONCLUSION Multiple synchronous lung cancers can be accompanied by hilar lymph node metastasis of small cell carcinomas of unknown origin. | Ryusei Yoshino Nana Yoshida Shunsuke Yasuda Akane Ito Masaki Nakatsubo Sayaka Yuzawa Masahiro Kitada | 2023 | World Journal of Clinical Cases2023，11，25： | 0 |
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