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480篇 您的检索式:作者名="Ryan E J"
    题名 作者 年代 出处 被引量
1Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis显示文摘Rayner Katey J Sheedy Frederick J Esau Christine C Hussain Farah N Temel Ryan E Parathath Saj van Gils Janine M Rayner Alistair J Chang Aaron N Suarez Yajaira Fernandez-Hernando Carlos Fisher Edward A Moore Kathryn J 2011Journal of Clinical Investigation2011,,7:2
2HIF-1α is required for solid tumor formation and embryonic vascularization显示文摘Ryan H E Lo J Johnson R S 1998EMBO J1998,17,11:2
3A new framework for reverse cholesterol transport: Non-biliary contributions to reverse cholesterol transport显示文摘Reduction of low-density lipoprotein-cholesterol through statin therapy has only modestly decreased coronary heart disease (CHD)-associated mortality in developed countries, which has prompted the search for alternative therapeutic strategies for CHD. Major efforts are now focused on therapies that augment high-density lipoprotein (HDL)-mediated reverse cholesterol transport (RCT), and ultimately increase the fecal disposal of cholesterol. The process of RCT has long been thought to simply involve HDL-mediated delivery of peripheral cholesterol to the liver for biliary excretion out of the body. However, recent studies have revealed a novel pathway for RCT that does not rely on biliary secretion. This nonbiliary pathway rather involves the direct excretion of cholesterol by the proximal small intestine. Compared to RCT therapies that augment biliary sterol loss, modulation of non-biliary fecal sterol loss through the intestine is a much more attractive therapeutic strategy, given that excessive biliary cholesterol secretion can promote gallstone formation. However, we are at an early stage in understanding the molecular mechanisms regulating the non-biliary pathway for RCT, and much additional work is required in order to effectively target this pathway for CHD prevention. The purpose of this review is to discuss our current understanding of biliary and nonbiliary contributions to RCT with particular emphasis on the possibility of targeting the intestine as an inducible cholesterol secretory organ.Ryan E Temel J Mark Brown 2010World Journal of Gastroenterology2010,16,47:2
4The elemental composition of street dust from large and small urban areas related to city type,source and particle size显示文摘Fergusson J E Ryan D E 1984Science of the Total Environment1984,34,:2
5Synthesis of anthracycline C-glycosyl isosteres 显示文摘ACTION E M RYAN K J TRACY M 1986Tetrahedron Lett1986,27,:1
6Control Topology Options for Single-Phase UPS Inverters显示文摘 Brumsickle W E Lorenz R D 1996Power Electronics Drivers and Growth1996,,8:1
7显示文摘Shapiro A Lakey J Ryan E 2000N Engl J Med2000,343,:1
8S1- opoke epi-cadmium neutron flux in activation analysis显示文摘HOLZBECHER J CHATT A RYAN D E 1985Canadian Journal of Spectroscopy1985,30,3:1
9Does video - assisted thoracic surgery provide a safe alternative to conventional tech- niques in patients with limited pulmonary function who are other- wise suitable for lung resection? 显示文摘OPARKA J YAN T D RYAN E 2013Interact Cardiovasc Thorac Surg2013,17,1:1
10Extremely Metal-poor Stars II:Elemental Abundances and the Early Chemical Enrichment of the Galaxy显示文摘RYAN S G NORRIS J E BEERS T C 1996ApJ1996,471,:1
11Percutaneous transthoracic needle aspiration biopsy显示文摘RYAN C LARSCHEID PATRICIA E THORPE WALTER J SCOTT 1998Chest1998,114,:1
12Effecct of acarbose on insulin sensitivity in elderly patients with diabetes显示文摘MENEILLY G S RYAN E A RAAADZIUUK J 2000Diabetes Care2000,23,8:1
13The global de-cline of reptiles, d6j6 vu amphibians 显示文摘Gibbon J W Scott D E Ryan T J 2000BioScience2000,50,8:1
14Self-determination in a work organization显示文摘DECI E L CONNELL J P RYAN R M 1989Journal of Applied Psychology1989,74,4:1
15Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen显示文摘SHAPIRO A M LAKEY J R RYAN E A 2000N Engl J Med2000,343,4:1
16Analysis of several phenolic compounds with potential antioxidant properties in grape extracts and wines by high- performance liquid chromatography - photodiode array detection without sample preparation显示文摘 Ryan J M 2000J Chrom2000,,:1
17Neutron Capture Element In s-process-rich,Very Metal-poor Stars显示文摘AOKI W RYAN S G NORRIS J E 2001ApJ2001,561,:1
18Self-determination in a work organization显示文摘DECI E L CONNELL J P RYAN R M 1989Journal of Applied Psychology1989,74,:1
19Aluminum tolerance in plants and the complexing role of organic acids显示文摘Ma J F Ryan P R Delhaize E 2001Trends Ham Sci2001,6,6:1
20A Subaru/high Dispersion Spectrograph Study of Lead Abundances in Eight s-process Element-rich, Metal-poor Stars 显示文摘AOKI W RYAN S G NORRIS J E 2002ApJ2002,580,:1
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