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| 1 | Cytokines,cytokine gene polymorphisms and Helicobacter pylori infection:Friend or foe?显示文摘Helicobacter pylori(H.pylori)is a flagellated,spiralshaped,microaerophilic Gram-negative bacillus that colonises the gastric mucosa of more than 50%of the human population.Infection is a risk factor for gastritis,ulcer disease and stomach cancer.Immunity against H.pylori is mainly related to Th1/Th17 skewing,and the activation of regulatory T cells is the main strategy used to limit inflammatory responses,which can result in the pathogen persistence and can lead to chronic gastrointestinal diseases,including cancer.Furthermore,host genetic factors that affect cytokines may determine differences in the susceptibility to many diseases.In this review,we present the cytokine profiles and the main cytokine gene polymorphisms associated with resistance/susceptibility to H.pylori and discuss how such polymorphisms may influence infection/disease outcomes. | Camila A Figueiredo Cintia Rodrigues Marques Ryan dos Santos Costa Hugo Bernardino F da Silva Neuza M Alcantara-Neves | 2014 | World Journal of Gastroenterology2014，20，18： | 11 |
| 2 | Realistic expectations and a dis- ease management model for depressed patients with persistent symp- toms 显示文摘 | Keitner GI Ryan CE Solomon DA | 2006 | The Journal of Clinical Psychiatry2006，67，： | 1 |
| 3 | The association of ill- ness uncertainty to parent and youth adjustment in juvenile rheumatic diseases:effect of youth age显示文摘 | Fedele DA Ramsey RR Ryan JL | 2011 | J Dev Behav Pedi- atr2011，32，5： | 1 |
| 4 | Realistic expectations and a disease management model for depressed patients with persistent symptoms显示文摘 | Keitner GI Ryan CE Solomon DA | 2006 | J Clin Psychiatry2006，67，9： | 1 |
| 5 | Coordinate up-regulation of hypoxia inducible factor (HIF)-la and HIF-1 target genes during multi-stage epidermal carcinogenesis and wound healing显示文摘 | Elson DA Ryan HE Snow JW | | Cancer Res0，2，： | 1 |
| 6 | Degenerative anular changes induced by puncture are associated with insufficiency of disc biomechanical function 显示文摘 | Hsieh AH Hwang D Ryan DA | 2009 | Spine2009，34，10： | 1 |
| 7 | Lithium plus valproate as maintenance polypharmacy for patients with bipolar Ⅰ disorder:A review显示文摘 | Solomaon DA Keitner GI Ryan CE | 1998 | J Clin Psychopharmacol1998，18，1： | 1 |
| 8 | Absorption, disposition, and metabolism of rosiglitazone, a potent thiazolidinedione insulin sensitizer, in humans显示文摘 | Cox PJ Ryan DA Hollis FJ | 2000 | Drug Metab Dispos2000，28，7： | 1 |
| 9 | Cilengitide (EMD 121974, NSC 707544) in asymptomatic metastatic castration resistant prostate cancer patients: a randomized phase I1 trial by the prostate cancer clinical trials consortium显示文摘 | Bradley DA Daignault S Ryan C J | 2010 | Investigational New Drugs2010，29，6： | 1 |
| 10 | A comparison of esomeprazole and lansoprazole for control of intragastric pH in patients with symptoms of gastro-oesophageal reflux disease 显示文摘 | Johnson DA Stacy T Ryan M | 2005 | Aliment Pharmacol Ther2005，22，2： | 1 |
| 11 | A comparision of esomeprazole and lansoprazole for control of intragastric pH in patients with symptoms of gastro-oesophageal reflux disease显示文摘 | Johnson DA Stacy T Ryan M | 2005 | J Aliment pharmaeol Ther2005，22，2： | 1 |
| 12 | Dose response re lationship of prenatal mercury exposure and IQ: an integra- tive analysis of epidemiologic data显示文摘 | Axelrad DA Bellinger DC Ryan LM etal | 2007 | Environ Health Per spect2007，115，4： | 1 |
| 13 | Objective estimates of the probability of death from bum injuries 显示文摘 | Ryan CM Sehoenfeld DA Thorpe WP | 1998 | N Engl J Med1998，338，： | 1 |
| 14 | Aβ-ttirected single-chain antibody delivery via a serotype-1 AAV vector improves learning behavior and pathology in Alzheimer's disease mice显示文摘 | Ryan DA Mastrangelo MA Narrow WC | 2010 | Mol Ther2010，18，8： | 1 |
| 15 | Sensitivity and specificity of the Distress Thermometer and a two - item depression screen (Patient Health Questionnaire - 2) with a 'help' question for psy-chological distress and psychiatric morbidity in patients with ad- vanced eaneer显示文摘 | Ryan DA Gallagher P Wright S | 2012 | Psyehooncology2012，21，12： | 1 |
| 16 | Guidelines for evaluating wet packs显示文摘 | Karle DA Ryan P | 1983 | AORN Journal1983，38，2： | 1 |
| 17 | Realistic expectations and a disease management model for depressed patients with persis tent symptoms显示文摘 | Keitner Gi Ryan CE Solomon DA | 2006 | J Clin Psychiatry2006，67，： | 1 |
| 18 | Effects of blood flow on skirl heating induced by millimeter wave irradiation in humans显示文摘 | Walters TJ Ryan KL Nelson DA | 2004 | Heahh Phys2004，86，2： | 1 |
| 19 | Realistic expectations and a disease management model for depressed patients with persistent symptoms显示文摘 | Keitner GI Ryan CE Solomom DA | 2006 | J Clin Psychiatry2006，67，9： | 1 |
| 20 | Endothelial colony- forming ceils from preterm infants are increased and more susceptible to hyperoxia显示文摘 | Baker CD Ryan SL Ingrain DA | 2009 | Am J Respir Crit Care Med2009，180，5： | 1 |
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