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| 1 | Impact of built environment on physical activity and obesity among children and adolescents in China:A narrative systematic review显示文摘Background: Neighborhood built environment may profoundly influence children's physical activity(PA) and body weight. This study systematically reviewed scientific evidence regarding the impact of built environment on PA and obesity among children and adolescents in China.Methods: A keyword and reference search was conducted in Active Living Research, Cochrane Library, PubMed, and Web of Science. Studies that met all of the following criteria were included in the review:(1) study designs—experimental studies, observational studies, and qualitative studies;(2) study subjects—Chinese children and/or adolescents aged 17 years;(3) exposures—neighborhood built environment;(4)outcomes—PA and/or body weight status;(5) article type—peer-reviewed publications;(6) time window of search—from the inception of an electronic bibliographic database to May 31, 2018;(7) country—China; and(8) language—articles written in English.Results: A total of 20 studies, including 16 cross-sectional studies, 3 longitudinal studies, and 1 descriptive study, met the predetermined selection criteria and were included in the review. A total of 13 studies adopted subjective built environment measures reported by parents and/or children, 2 adopted objective measures(e.g., geographical information system, field observations), and 5 adopted both objective and subjective measures. PA behaviors included PA, physical inactivity, sedentary behavior, active/passive commuting from/to school, and park visits. Among the 16 studies that provided some quantitative estimates of the influence of built environment on PA and body weight status, all reported a statistically significant relationship in the expected direction. Availability and accessibility in proximity to greenspaces, parks, recreational facilities,and sidewalks were found to be associated with increased PA levels, reduced sedentary behaviors, and/or active commuting among Chinese children and adolescents. In contrast, the absence of bike lanes and living in higher density residential areas were associated with increased likelihood of childhood overweight and obesity.Conclusion: Neighborhood built environment plays an important role in Chinese children's PA engagement and weight outcomes. Building new exercise facilities and enhancing the accessibility of existing facilities hold the potential to enhance PA engagement among Chinese children and adolescents. In addition, urban designs that incorporate sidewalks, bike lanes, walking paths, less motorized traffic, and lower residential density are likely to promote PA and prevent childhood obesity in China. | Ruopeng An Jing Shen Qiuying Yang Yan Yang | 2019 | Journal of Sport and Health Science2019，8，2： | 13 |
| 2 | Radiotherapy in combination with systemic therapies for brain metastases:current status and progress显示文摘Brain metastases(BMs)are the most common cause of intracranial neoplasms in adults with poor prognosis.Most BMs originate from lung cancer,breast cancer,or melanoma.Radiotherapy(RT),including whole brain radiotherapy(WBRT)and stereotactic radiation surgery(SRS),has been widely explored and is considered a mainstay anticancer treatment for BMs.Over the past decade,the advent of novel systemic therapies has revolutionized the treatment of BMs.In this context,there is a strong rationale for using a combination of treatments based on RT,with the aim of achieving both local disease control and extracranial disease control.This review focuses on describing the latest progress in RT as well as the synergistic effects of the optimal combinations of RT and systemic treatment modalities for BMs,to provide perspectives on current treatments. | Lei Liu Wanqi Chen Ruopeng Zhang Yuekun Wang Penghao Liu Xin Lian Fuquan Zhang Yu Wang Wenbin Ma | 2020 | Cancer Biology & Medicine2020，17，4： | 5 |
| 3 | Projecting the impact of the coronavirus disease-2019 pandemic on childhood obesity in the United States: A microsimulation model显示文摘Purpose:The coronavirus disease-2019(COVID-19)pandemic in the United States led to nationwide stay-at-home orders and school closures.Declines in energy expenditure resulting from canceled physical education classes and reduced physical activity may elevate childhood obesity risk.This study estimated the impact of COVID-19 on childhood obesity.Methods:A microsimulation model simulated the trajectory of a nationally representative kindergarten cohort’s body mass index z-scores and childhood obesity prevalence from April 2020 to March 2021 under the control scenario without COVID-19 and under the 4 alternative scenarios with COVID-19—Scenario 1:2-month nationwide school closure in April and May 2020;Scenario 2:Scenario 1 followed by a 10%reduction in daily physical activity in the summer from June to August;Scenario 3:Scenario 2 followed by 2-month school closure in September and October;and Scenario 4:Scenario 3 followed by an additional 2-month school closure in November and December.Results:Relative to the control scenario without COVID-19,Scenarios 1,2,3,and 4 were associated with an increase in the mean body mass index z-scores by 0.056(95%confidence interval(95%CI):0.0550.056),0.084(95%CI:0.0840.085),0.141(95%CI:0.1400.142),and 0.198(95%CI:0.1970.199),respectively,and an increase in childhood obesity prevalence by 0.640(95%CI:0.5150.765),0.972(95%CI:0.8191.126),1.676(95%CI:1.4751.877),and 2.373(95%CI:2.1352.612)percentage points,respectively.Compared to girls and non-Hispanic whites and Asians,the impact of COVID-19 on childhood obesity was modestly larger among boys and non-Hispanic blacks and Hispanics,respectively.Conclusion:Public health interventions are urgently called to promote an active lifestyle and engagement in physical activity among children to mitigate the adverse impact of COVID-19 on unhealthy weight gains and childhood obesity. | Ruopeng An | 2020 | Journal of Sport and Health Science2020，9，4： | 4 |
| 4 | Electrodeposition:Synthesis of advanced transition metal-based catalyst for hydrogen production via electrolysis of water显示文摘Developing lower-cost and higher-effective catalyst to support hydrogen(H_(2))production by electrochemical water-splitting has been recognized as a preferred strategy to drive the clean energy utilization.As a credible technology for the synthesis of functional materials,electrodeposition has attracted widespread attention,especially suitable for non-noble transition metal-based catalysts(TMCs).Recently,lots of researchers have been devoted to this hot research direction with plentiful achievements,however,a comprehensive review towards this area is still missing.Hence,we summarize the past research progress,presents the technical characteristics of electrodeposition from the viewpoint of fundamental theory and influence factors for the electrochemical deposition behavior,and introduce its application in various of TMCs with versatile nanostructures and compositions.Except a deeper and more comprehensive cognition of electrodeposition,we further discuss the catalyst’s optimized hydrogen evolution reaction(HER),oxygen evolution reaction(OER)performance as well as overall water splitting that combined with the synthetic process.Finally,we conclude the technical advantages towards electrodeposition,propose challenge and future research directions in this promising field.This timely review aims to promote a deeper understanding of effective catalysts obtained via electrodeposition strategy,and provide new guidance for the design and synthesis of future catalysts for hydrogen production. | Ruopeng Li Yun Li Peixia Yang Dan Wang Hao Xu Bo Wang Fan Meng Jinqiu Zhang Maozhong An | 2021 | Journal of Energy Chemistry2021，30，6： | 4 |
| 5 | Optimization of mechanical and damping properties of Mg-0.6Zr alloy by different extrusion processing显示文摘In this study,the optimization of mechanical and damping capacities of Mg-0.6 wt.%Zr alloys by controlling the recrystallized(DRXed)grain size under varying extrusion processing parameters including extrusion temperature T and strain rate was investigated.The relationship between the DRXed grain size and damping properties of the studied alloy was also discussed.The DRXed grain size of the as-extruded Mg-Zr alloys decreased as the extrusion temperature T decreased and the strain rateεincreased.As the DRXed grain size decreased,the strength and elongation of the as-extruded alloys exhibited improved performance through the grain refinement mechanism,while the damping properties deteriorated.The extrusion temperature of the Mg-Zr alloy had relatively greater effects on the mechanical and damping properties than the strain rate.The results of the present work indicate that alloys with appropriate mechanical and damping properties may be obtained from controlling the DRXed grain size by careful tailoring of the extrusion process parameters. | Jingfeng Wang Zhongshan Wu Shan Gao Ruopeng Lu Dezhao Qin Wenxiang Yang Fusheng Pan | 2015 | Journal of Magnesium and Alloys2015，3，1： | 4 |
| 6 | Trimetallic Au@PdPb nanowires for oxygen reduction reaction显示文摘The development of highly efficient and stable Pd-based catalysts is crucial to improve their sluggish oxygen reduction reaction(ORR)kinetics in acid media.To improve ORR activity and utilization efficiency of Pd,an ideal catalyst should have ORR-favorable chemical environment,optimized geometric structure,and long periods of operation.In this work,we first synthesize a novel trimetallic Au@PdPb core–shell catalyst consisting of PdPb alloy nano-layers grown on the surface of ultrathin Au nanowires(NWs)by a two-step water-bath method.The Au@PdPb NWs have the merits of anisotropic one-dimensional nanostructure,high utilization efficiency of Pd atoms and doping of Pb atoms.Because of the structural and multiple compositional advantages,Au@PdPb NWs exhibit remarkably enhanced ORR activity with a high haIf-wave potential(0.827 V),much better than those of commercial Pd black(0.788 V)and bimetallic Au@Pd NWs(0.803 V).Moreover,Au@PdPb NWs display better electrocatalytic stability for the ORR than those of Pd black and Au@Pd NWs.This study demonstrates the validity of our approach for deriving highly ORR-active Pd-based catalysts by modifying their structure and composition. | Xian Jiang Yuexin Xiong Ruopeng Zhao Jiancheng Zhou Jong-Min Lee Yawen Tang | 2020 | Nano Research2020，13，10： | 3 |
| 7 | Study of Cell Behaviors on Anodized TiO_2 Nanotube Arrays with Coexisting Multi-Size Diameters显示文摘It has been revealed that the different morphologies of anodized TiO_2 nanotubes, especially nanotube diameters, triggered different cell behaviors. However, the influence of TiO_2 nanotubes with coexisting multi-size diameters on cell behaviors is seldom reported. In this work, coexisting four-diameter TiO_2 nanotube samples, namely,one single substrate with the integration of four different nanotube diameters(60, 150, 250, and 350 nm), were prepared by repeated anodization. The boundaries between two different diameter regions show well-organized structure without obvious difference in height. The adhesion behaviors of MC3T3-E1 cells on the coexisting fourdiameter TiO_2 nanotube arrays were investigated. The results exhibit a significant difference of cell density between smaller diameters(60 and 150 nm) and larger diameters(250 and 350 nm) within 24 h incubation with the coexistence of different diameters, which is totally different from that on the single-diameter TiO_2 nanotube arrays. The coexistence of four different diameters does not change greatly the cell morphologies compared with the singlediameter nanotubes. The findings in this work are expected to offer further understanding of the interaction between cells and materials. | Yifan Chen Jiahua Ni Hongliu Wu Ruopeng Zhang Changli Zhao Wenzhi Chen Feiqing Zhang Shaoxiang Zhang Xiaonong Zhang | 2016 | Nano-Micro Letters2016，8，1： | 2 |
| 8 | Metamaterials: Reshape and Rethink显示文摘Metamaterials are composite materials whose material properties(acoustic, electrical, magnetic, or optical, etc.) are determined by their constitutive structural materials, especially the unit cells. The development of metamaterials continues to redefine the boundaries of materials science. In the field of electromagnetic research and beyond, these materials offer excellent design flexibility with their customized properties and their tunability under external stimuli. In this paper, we first provide a literature review of metamaterials with a focus on the technology and its evolution. We then discuss steps in the industrialization process and share our own experience. | Ruopeng Liu Chunlin Ji Zhiya Zhao Tian Zhou | 2015 | Engineering2015，1，2： | 2 |
| 9 | Association of single nucleotide polymorphisms of brain-derived neurotrophic factor gene and multidrug resistance 1 gene to refractory epilepsy in Chinese Han children显示文摘BACKGROUND:There are two hypotheses for the underlying cause of refractory epilepsy:'target'and'transport'.Studies have shown that brain-derived neurotrophic factor(BDNF) is over-expressed in refractory epilepsy.Multidrug resistance 1(MDR1) gene encodes for P-glycoprotein,the primary ATP-binding cassette transporter in the human body.Some single nucleotide polymorphisms of the MDR1 gene have been associated with refractory epilepsy. OBJECTIVE:To investigate the association between BDNF gene C270T polymorphism and MDR1 T-129C polymorphism with refractory epilepsy in Chinese Han children through the use of polymerase chain reaction(PCR)-restriction fragment length polymorphism analysis. DESIGN,TIME AND SETTING:A case-control,genetic association study was performed at the Central Laboratory,Third Xiangya Hospital of Central South University from June 2005 to November 2007. PARTICIPANTS:A total of 84 cases of unrelated children with epilepsy,including 41 cases of refractory epilepsy and 43 cases of drug-responsive epilepsy,were enrolled.An additional 30 healthy,Chinese Han children,whose ages and gender matched the refractory epilepsy patients, were selected as normal controls. METHODS:Venous blood was collected and genomic DNA was extracted from the blood specimens.C270T polymorphism in BDNF gene and T-129C polymorphism in MDR1 gene were genotyped using PCR-restriction fragment length polymorphism analysis.Association analysis using the Ftest and Chi-square test was statistically performed between C270T polymorphism in BDNF gene and T-129C polymorphism in MDR1 gene and refractory epilepsy. MAIN OUTCOME MEASURES:The distribution of genotypes and allele frequencies of C270T polymorphism in BDNF gene and T-129C polymorphism in MDR1 gene. RESULTS:The distribution of CC,CT,and TT genotypes,as well as C and T allele frequencies,in the BDNF gene was not significantly different between the refractory epilepsy group, drug-responsive epilepsy group,or the normal control group(P>0.05).The distribution of TT genotype and T allele frequencies of the MDR1 gene was significantly different in the refractory epilepsy group compared with the drug-responsive epilepsy and normal control groups(P<0.05). Comparison of haplotype combinations demonstrated that there were no significant differences in combinations of TT+CC,TT+CT,TC+CC,and TC+CT among the three groups(P>0.05). CONCLUSION:C270T polymorphism of the BDNF gene was not associated with refractory epilepsy in Chinese Han children,but T-129C polymorphism in the MDR1 gene was associated with refractory epilepsy in Chinese Han children.The TT genotype and T allele frequencies could serve as susceptibility loci for refractory epilepsy.Interactions between C270T in BDNF gene and T-129C in MDR1 gene were not observed in refractory epilepsy in Chinese Han children. | Guangxin Wang Zuocheng Yang Ruifeng Jin Ruopeng Sun | 2009 | Neural Regeneration Research2009，4，11： | 2 |
| 10 | Peroxidase from foxtail millet bran exerts anticolorectal cancer activity via targeting cellsurface GRP78 to inactivate STAT3 pathway显示文摘Molecular targeted therapy has become an emerging promising strategy in cancer treatment,and screening the agents targeting at cancer cell specific targets is very desirable for cancer treatment.Our previous study firstly found that a secretory peroxidase of class III derived from foxtail millet bran(FMBP)exhibited excellent targeting anti-colorectal cancer(CRC)activity in vivo and in vitro,whereas its underlying target remains unclear.The highlight of present study focuses on the finding that cell surface glucose-regulated protein 78(cs GRP78)abnormally located on CRC is positively correlated with the anti-CRC effects of FMBP,indicating it serves as a potential target of FMBP against CRC.Further,we demonstrated that the combination of FMBP with the nucleotide binding domain(NBD)of cs GRP78interfered with the downstream activation of signal transducer and activator of transcription 3(STAT3)in CRC cells,thus promoting the intracellular accumulation of reactive oxygen species(ROS)and cell grown inhibition.These phenomena were further confirmed in nude mice tumor model.Collectively,our study highlights cs GRP78 acts as an underlying target of FMBP against CRC,uncovering the clinical potential of FMBP as a targeted agent for CRC in the future. | Shuhua Shan Jinping Niu Ruopeng Yin Jiangying Shi Lizhen Zhang Caihong Wu Hanqing Li Zhuoyu Li | 2022 | Acta Pharmaceutica Sinica B2022，12，3： | 2 |
| 11 | Resonant crystal bandgap metamaterials in microwave regime and their exotic amplification of evanescent waves显示文摘 | Ruopeng Liu Tie Jun Off Bo Zhao Xian Qi Lin Hui Feng Ma Da Huang D R Smith | 2007 | Appl Phys Lett2007，90，09： | 1 |
| 12 | Effect of long period stacking ordered (LPSO) structure on the damping capacities of Mg-Cu-Mn-Zn-Y alloys显示文摘 | WANG Jingfeng LU Ruopeng WEI Wenwen | 2012 | Journal of Alloys and Compounds2012，537，5： | 1 |
| 13 | Circuit verification of tunneling effect in zero permit-tivity medium 显示文摘 | CHENG Qiang LIU Ruopeng HUANG Da | 2007 | Appl Phys Lett2007，91，23： | 1 |
| 14 | Synergistic Interfacial and Doping Engineering of Heterostructured NiCo(OH)_(x)-Co_(y)W as an Efficient Alkaline Hydrogen Evolution Electrocatalyst显示文摘To achieve high efficiency of water electrolysis to produce hydrogen(H_(2)),developing non-noble metal-based catalysts with consid-erable performance have been considered as a crucial strategy,which is correlated with both the interphase properties and multi-metal synergistic effects.Herein,as a proof of concept,a delicate NiCo(OH)_(x)-CoyW catalyst with a bush-like heterostructure was realized via gas-template-assisted electrodeposition,followed by an electrochemical etching-growth process,which ensured a high active area and fast gas release kinetics for a superior hydrogen evolution reaction,with an overpotential of 21 and 139 mV at 10 and 500 mA cm^(−2),respectively.Physical and electrochemical analyses demonstrated that the synergistic effect of the NiCo(OH)_(x)-Co_(y)W heteroge-neous interface resulted in favorable electron redistribution and faster electron transfer efficiency.The amorphous NiCo(OH)_(x) strengthened the water dissociation step,and metal phase of CoW provided sufficient sites for moderate H immediate adsorption/H_(2) desorption.In addition,NiCo(OH)_(x)-CoyW exhibited desirable urea oxidation reaction activity for matching H_(2) generation with a low voltage of 1.51 V at 50 mA cm^(−2).More importantly,the synthesis and testing of the NiCo(OH)_(x)-CoyW catalyst in this study were all solar-powered,sug-gesting a promising environmentally friendly process for practical applications. | Ruopeng Li Hao Xu Peixia Yang Dan Wang Yun Li Lihui Xiao Xiangyu Lu Bo Wang Jinqiu Zhang Maozhong An | 2021 | Nano-Micro Letters2021，13，8： | 1 |
| 15 | Acute Inhibition of Rho-Kinase Attenuates Pulmonary Hypertension in Patients with Congenital Heart Disease显示文摘 | Fuhai Li Wei Xia Shuanghu Yuan Ruopeng Sun | 2009 | Pediatric Cardiology2009，，3： | 1 |
| 16 | Metamaterials beyond negative refractive index: Applications in telecommunication and sensing显示文摘Metamaterials have earned their name with extraordinary properties such as negative refractive index and invisibility cloaking. With over 15 years of research and development, metamaterials show their debut in real world applications, especially in the areas of telecommunication, sensing, aerospace & defense, optics and medical instrumentation. In the meanwhile, metamaterials are expanding their concept in areas beyond electromagnetics. In this paper, the authors would like to focus on the research and applications in telecommunication and sensing. Octave-bandwidth horn antennas, flat-panel satellite antennas and air-borne holographic satellite antennas are all fabulous examples of clever implementation that bring metamaterials into practical devices. We would like to discuss the features that differentiate metamaterials from conventional counterparts in case studies. With the advancement in design, manufacturing, packaging, detection and testing, more sophisticated features are expected in the telecommunication, sensing, and beyond. | LIU RuoPeng ZHAO ZhiYa JI ChunLin ZHOU Tian | 2016 | Science China(Technological Sciences)2016，59，7： | 1 |
| 17 | MicroRNA-26a acts as a tumor suppressor inhibiting gallbladder cancercell proliferation by directly targeting HMGA2显示文摘 | Huading Zhou Weijie Guo Yingjun Zhao Yifei Wang Ruopeng Zha Jie Ding Linhui Liang Jun Hu Hao Shen Zongyou Chen Baobing Yin Baojin Ma | 2014 | International Journal of Oncology2014，，6： | 1 |
| 18 | Engagement in outdoor physical activity under ambient fine particulate matter pollution: A risk-benefit analysis显示文摘Background:Outdoor physical activity(PA)brings important health benefits,but exposure to polluted air increases health risks.This study aimed to quantify the tradeoff of PA under fine particulate matter(PM_(2.5))air pollution by estimating the optimal PA duration under various pollution levels.Methods:A risk-benefit analysis was performed to estimate the optimal outdoor moderate-intensity PA(MPA)duration under varying PM_(2.5) concentrations.Results:An inverse nonlinear relationship was identified between optimal MPA duration and background PM_(2.5) concentration levels.When background PM_(2.5) concentration increased to 186 μg/m^(3),the optimal outdoor MPA duration decreased to 2.5 h/week,the minimum level recommended by current PA guidelines.When background PM_(2.5) concentration further increased to 235 μg/m^(3),the optimal outdoor MPA duration decreased to 1 h/week.The relationship between optimal MPA duration and background PM_(2.5) concentration levels was stronger when exercising at a location closer to a source of air pollution.Compared to the general adult population,adults aged 60 years and older had substantially steeper curves—the optimal outdoor MPA duration decreased to 2.5 h/week when background PM_(2.5) concentration reached 45 μg/m^(3).Conclusion:The health benefit of outdoor MPA by far outweighs the health risk of PM_(2.5) pollution for the global average urban background concentration(22 μg/m^(3),).This modeling study examined a single type of air pollutant and suffered from measurement errors and estimation uncertainties.Future research should examine other air pollutants and indoor PA,incorporate short-and mid-term health effects of MPA and air pollution into the risk-benefit analysis,and provide estimates specific for high-risk subgroups. | Ruopeng An Hyojung Kang Lianzhong Cao Xiaoling Xiang | 2022 | Journal of Sport and Health Science2022，11，4： | 1 |
| 19 | Defining Adaptation Con- straints for Business Process Variants显示文摘 | Lu Ruopeng Sadiq S W Govematori G | 2009 | Business Information Sys- tems2009，，： | 1 |
| 20 | Microstructural Impact of Ischemia and Bone Marrow–Derived Cell Therapy Revealed With Diffusion Tensor Magnetic Resonance Imaging Tractography of the Heart In Vivo显示文摘 | David E. Sosnovik Choukri Mekkaoui Shuning Huang Howard H. Chen Guangping Dai Christian T. Stoeck Soeun Ngoy Jian Guan Ruopeng Wang William J. Kostis Marcel P. Jackowski Van J. Wedeen Sebastian Kozerke Ronglih Liao | 2014 | Circulation2014，，： | 1 |
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