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| 1 | Virus profile in children with acute respiratory infections with various severities in Beijing, China显示文摘 | Zhu Runan Song Qinwei Qian Yuan Zhao Linqing Deng Jie Wang Fang Sun Yu | 2014 | Chinese Medical Journal2014，，21： | 10 |
| 2 | Human rhinovirus C infection is associated with asthma in children determined by x TAG respiratory viral panel FAST显示文摘Dear Editor,Cumulative evidence supports the role of early-life viral infections,especially respiratory syncytial virus(RSV)and human rhinovirus(HRV),as major antecedents of childhood asthma(Lemanske,2002;Jackson et al.,2008).In this study,the x TAG respiratory viral panel FAST(RVP FAST)assay,a multiplex polymerase chain reaction(PCR)-based method(Arens et al.,2010;BaladaLlasat et al.,2011;Gharabaghi et al.,2011;Selvaraju,2012),was used to investigate the association of infec- | Dongmei Chen Qinwei Song Runan Zhu Yuan Qian Yu Sun Jie Deng Fang Wang Yaxin Ding Run Tian Chuanhe Liu Wenjing Zhu Linqing Zhao | 2017 | Virologica Sinica2017，32，2： | 5 |
| 3 | Gadd45a deletion aggravates hematopoietic stem cell dysfunction in ATM-deficient mice显示文摘混乱毛细管扩张变异(ATM ) kinase 在 genomic 的维护起一个必要作用稳定性。ATM 缺乏(ATM/) 老鼠展出造血的干细胞(HSC ) 机能障碍和淋巴瘤的高发生。Gadd45a 控制房间周期拘捕, apoptosis 和 DNA 修理,并且涉及 ATM-p53 调停的 DNA 损坏反应。然而,在调整 ATM/ HSC 的功能的 Gadd45a 的角色是未知的。这里,我们报导那 Gadd45a 删除没在 ATM/ 鼠标救 T 房间和 B 房间开发的缺点。相反, ATM 和 Gadd45a 加倍 HSC 展出了的大美人(ATM/Gadd45a/) 在与在 HSC 移植的 ATM/ HSC 相比的长期的自强能力的一个加重的缺点试验。进一步的实验表明 ATM/Gadd45a/ HSC 的加重的缺点由于房间增长的减小,包括 p53-p21 发信号的一条起来规定与 DNA 损坏的累积和 DNA 损坏反应的随后的激活联系了小径。另外, ATM/Gadd45a/ 老鼠比 ATM/ 老鼠显示出造血的恶意,以及转移的增加的率的增加的发生。在结论, Gadd45a 删除加重了 DNA 损坏累积,它随后在 ATM/ HSC 导致了一个进一步损害的自强能力和增加的恶意的转变。 | Yulin Chen Runan Yang Peng Guo Zhenyu Ju | 2014 | Protein & Cell2014，5，1： | 4 |
| 4 | Highly Improved Microstructure and Properties of Poly(p-phenylene terephthalamide) Paper-based Materials via Hot Calendering Process显示文摘In this study,the effect of hot calendering process on the microstructure and properties of poly(p-phenylene terephthalamide)(PPTA) paper-based materials was investigated.The microstructures of the fracture surface,crystalline structure,and single fiber strength of the PPTA paperbased materials as well as the different bonding behaviors between the PPTA fibers and PPTA fibrids obtained before and after the hot calendering process were examined.The results indicated that a high linear pressure would result in a limited improvement of the strength owing to the unimproved paper structure.The optimal values of tensile index and dielectric strength of 56.6 N·m/g and 27.6 kV/mm,respectively,could only be achieved with a synergistic effects of hot calendering temperature and linear pressure(240℃ and 110 k N/m,respectively).This result suggested it was possible to achieve a significant reinforcement and improvement in the interfacial bonding of functional PPTA paper-based materials,and avoid the formation of unexpected pleats and cracks in PPTA paper-based materials during the hot calendering process. | Bin Yang ZhaoQing Lu MeiYun Zhang ShunXi Song RuNan Wang | 2017 | Paper And Biomaterials2017，2，3： | 3 |
| 5 | Application of Human Adenovirus Genotyping by Phylogenetic Analysis in an Outbreak to Identify Nosocomial Infection显示文摘Nosocomial infections are common in pediatric patients and can be fatal in infants and immunocompromised patients. In September 2018, a high positive rate of human adenovirus HAdV was occurred among hospitalized children in the Children's Hospital Affiliated to the Capital Institute of Paediatrics in Beijing. To investigate whether this outbreak of HAdV was related to nosocomial infections or the result of community infections, we collected respiratory specimens from patients with acute respiratory infections in a respiratory ward during June to December 2018, and screened for respiratory viruses. Among 1,840 cases included, 95(5.2%, 95/1840) were positive for HAdV and 81 were genotyped based on phylogenetic analysis, including seven as HAdV-1(8.6%), 30 HAdV-3(37.0%), two HAdV-6(2.5%), and 42 HAdV-7(51.9%). More HAdV-positive samples were collected in August(4.7%, 12/255), September(15.0%, 41/274) and October(6.9%, 17/247), with a peak in September 2018. By combining the results of HAdV phylogenetic analysis with clinical data of patients, there were 77 cases(4.2%, 77/1840;81.1%, 77/95) excluded from nosocomial infections, eight cases representing possible infections transmitted by visitors or attending parents, three cases without sequences that might have been due to infection transmitted by roommates positive for HAdV, one case of a roommate without an HAdV sequence, and six cases that shared highly homologous sequences with those of their roommates, for which nosocomial infections might be considered. In conclusion, genotyping of HAdVs based on phylogenetic analysis combined with clinical information provides a powerful method to distinguish nosocomial infections from community acquired infection, especially when tracing the origins of nosocomial infections. | Chuanyu Yang Chunmei Zhu Yuan Qian Jie Deng Baoyuan Zhang Runan Zhu Fang Wang Yu Sun Dongmei Chen Qi Guo Yutong Zhou Lei Yu Ling Cao Linqing Zhao | 2021 | Virologica Sinica2021，36，3： | 3 |
| 6 | Bamboo-inspired cell-scale assembly for energy device applications显示文摘Rapid advances in flexible and wearable smart textiles demand low-cost,high-energy/power-density fiber-shaped supercapacitors(FSCs).The performance of FSCs is determined by the fabrication and assembly of fiber-shaped electrodes(FSEs),where an active charge-storage material is always clad around flexible charge transmission current collectors.Inspired by the tissue structure of natural bamboo,wherein parenchyma cells(PCs)that store nutrients are clad around bamboo fibers(BFs),we propose a strategy for converting bamboo cells into FSEs using conductive BFs and activated PCs as current collectors and active materials,respectively.The assembled electrode has a high specific capacitance of 1454 mF cm^(−2) at 0.64 mA cm^(−2).A solid-state FSC with a pair of bamboo-structured electrodes exhibited a substantially high energy density.Its mechanical flexibility enabled the knitting of wearable wristbands to drive ultra-small voltmeter indicators.This lightweight,low cost,and high-energy-density bamboostructured FSC could enable numerous smart textile applications. | Qiuqin Lin Runan Gao Daohao Li Yun Lu Shiqin Liu Yanglun Yu Yuxiang Huang Wenji Yu | 2022 | npj Flexible Electronics2022，6，1： | 1 |
| 7 | Regenerating leather waste for flexible pressure sensing applications显示文摘Pressure sensor can be applied in a wide range of fields,such as voice recognition,human motions detection and artificial electronic skin,the sensing of which is greatly influenced by the flexibility and stretchability of substrate materials.Here,based on the piezoresistive effect,new kinds of flexible pressure sensors have been realized from a pair of flexible and biocompatible collagen films:one is coated by silver nanowires(Ag NWs)and the other by interdigital electrode,respectively.The collagen films are regenerated from leather waste and could bring economic benefits to society.The prepared pressure sensors are applied for voice recognition and human motion detection. | Jie Lei Binghua Zou Runan Zhang Kang Zhang Ruijie Xie Weina Zhang Jiansheng Wu Sheng Li Bing Zheng Fengwei Huo | 2019 | Journal of Leather Science and Engineering2019，1，1： | 1 |
| 8 | A comparative study of oxidation of Cr( Ⅲ ) in aqueous ions, complex ions and insoluble compounds by manganese-beating mineral (bimessite) 显示文摘 | Dai Runan Yu Chanb-yuan Sun Rui | 2009 | Chemosphere2009，76，： | 1 |
| 9 | The study of modified talc powder on filler retention in papermaking 显示文摘 | Zhang Haitao Zhang Yunzhan Yang Runan | 2006 | Journal of Tianjin University of Science and technol ogy2006，，19： | 1 |
| 10 | Prevalence analysis of different human bocavirus genotypes in pediatric patients revealed intra-genotype recombination显示文摘 | Min Zhao Runan Zhu Yuan Qian Jie Deng Fang Wang Yu Sun Huijin Dong Liying Liu Liping Jia Linqing Zhao | 2014 | Infection, Genetics and Evolution2014，，： | 1 |
| 11 | China-Singapore Intergovernmental Cooperation and Economic and Trade Relations显示文摘Since the establishment of diplomatic relations between China and Singapore in 1990, both the economic and political ties between the two countries have experienced a substantial growth. China-Singapore Suzhou Industrial Park, China-Singapore(Chongqing) Demonstrative Initiative on Strategic Connectivity, and the compatibility between Singapore's development strategy and China's Belt and Road initiative are testimony to the ever-growing bilateral economic and trade links. The deepening and expanding economic and trade relations between China and Singapore enhance political mutual trust, propelling China's economic and industrial upgrading. At the same time, they exert a positive influence on the development of China-ASEAN relations and an effective implementation of the Belt and Road initiative in Southeast Asia. | Li Wei Zhao Runan | 2017 | Contemporary International Relations2017，27，6： | 0 |
| 12 | Leaf phenotypic variation in natural populations of Carpinus tschonoskii in China显示文摘Carpinus tschonoskii Maxim.exhibits rich leaf phenotypic variation and various leaf shapes,but few studies show why leaf phenotypic traits have such a large variation.Basic morphological markers may provide guidance for studying plant genetic variation and species protection and utilization.To study leaf phenotypic variations and the relationship between variation characteristics and climatic and geographical factors,phenotypic traits among natural populations were investigated.Results revealed that leaf phenotypes varied significantly among and within populations.Some populations had higher phenotypic diversity,while others had lower phenotypic diversity.Among the phenotypic traits,leaf area and petiole length had the most variation.Leaf index and primary lateral veins were the most stable phenotypes,which may be important reference indexes for phenotype identification in field investigations.There was a strong consistency between leaf phenotypic traits and geographical location.Plants in high latitudes tend to have longer leaves,and plants in low temperatures tend to have longer leaves and larger leaf perimeter.In addition,plants in areas with less rainfall have longer petioles.The 13 populations of C.tschonoskii can be divided into four branches by cluster analysis,and the results show a good relationship with the geographical location of each population.Additionally,some populations geographically isolated also had unique leaf phenotypes. | Runan Zhao Xiaojie Chu Qianqian He Wei Liu Zunling Zhu | 2023 | Journal of Forestry Research2023，34，5： | 0 |
| 13 | Radiated noise measurement method of underwater low noise target by a vertical nested array显示文摘A radiated noise measurement method of underwater acoustic targets with relatively low power by a vertical nested array is studied. Firstly, the array gain requirements for different frequency bands are obtained through comparative analysis of the background noise level and the radiated noise level of the target. Secondly, an ultra wideband constant-beamwidth beamforming method with high robustness is established for the waveguide environment based on convex optimization. The radiated noise measurement and the following spatial array signal processing procedure is formulated. Finally, a vertical nested array measurement system is developed, and the radiated noise measurement method is verified using lake test data. Experimental results show that the radiated noise measurement method has large working bandwidth, high robustness and low measurement uncertainty of about 2 dB. | LI Xuegang JIANG Guoqing SUN Guocang HUA Runan ZHU Jie | 2024 | Chinese Journal of Acoustics2024，43，1： | 0 |
| 14 | Simultaneous multi-material embedded printing for 3D heterogeneous structures显示文摘In order to mimic the natural heterogeneity of native tissue and provide a better microenvironment for cell culturing,multi-material bioprinting has become a common solution to construct tissue models in vitro.With the embedded printing method,complex 3D structure can be printed using soft biomaterials with reasonable shape fidelity.However,the current sequential multi-material embedded printing method faces a major challenge,which is the inevitable trade-off between the printed structural integrity and printing precision.Here,we propose a simultaneous multi-material embedded printing method.With this method,we can easily print firmly attached and high-precision multilayer structures.With multiple individually controlled nozzles,different biomaterials can be precisely deposited into a single crevasse,minimizing uncontrolled squeezing and guarantees no contamination of embedding medium within the structure.We analyse the dynamics of the extruded bioink in the embedding medium both analytically and experimentally,and quantitatively evaluate the effects of printing parameters including printing speed and rheology of embedding medium,on the 3D morphology of the printed filament.We demonstrate the printing of double-layer thin-walled structures,each layer less than 200μm,as well as intestine and liver models with 5%gelatin methacryloyl that are crosslinked and extracted from the embedding medium without significant impairment or delamination.The peeling test further proves that the proposed method offers better structural integrity than conventional sequential printing methods.The proposed simultaneous multi-material embedded printing method can serve as a powerful tool to support the complex heterogeneous structure fabrication and open unique prospects for personalized medicine. | Ziqi Gao Jun Yin Peng Liu Qi Li Runan Zhang Huayong Yang Hongzhao Zhou | 2023 | International Journal of Extreme Manufacturing2023，5，3： | 0 |
| 15 | More common RNAemia in the early stage of severe SARS-CoV-2 BF.7.14 infections in pediatric patients显示文摘The risk factors of severe infections in children during the severe acute respiratory syndrome coronavirus 2(SARS‐CoV‐2)outbreak in Beijing remain elusive.SARS‐CoV‐2‐positive children admitted to the intensive care unit(ICU)with collected plasma specimens were enrolled and screened for common pathogens using capillary electrophoresis‐based multiplex PCR from December 12,2022,to January 24,2023.The SARS‐CoV‐2 subvariants were identified using next‐generation sequencing.Plasma was positive for two(positive;P),one(suspicious;S),or no(negative;N)SARS‐CoV‐2 genes were classified as plasmatic RNA‐positive(RNAemia;P+S)or without RNAemia(N).Clinical and laboratory data of the enrolled cases were then collected and analyzed.The 34 enrolled children included 26 males and 24 younger than three years.All were negative for other respiratory pathogens.BF.7.14(18/29)was the predominant subvariant.Viral loads in respiratory specimens,hours from symptom onset to the first respiratory specimen collection(time‐variable),with comorbidities and BF.7.14 and BA.5.2 distributions were significantly different in P vs.N and RNAemia vs.without RNAemia group.Among most cases,the T lymphocyte ratios decreased,while the cytokine level and the B lymphocyte ratio increased.The time variables were 2.22±2.05 and 4.00±2.49 days in BF.7.14 and BA.5.2 infections,respectively.In conclusion,SARS‐CoV‐2 was more likely to cause severe infections among males aged≤3 years old with comorbidities during the SARS‐CoV‐2 outbreak in Beijing,while RNAemia is more common in children at the early stage of severe BF.7.14 infections,and most had high cytokine levels and B‐cell activation. | Yu Sun Runan Zhu Yang Pan Ri De Shuang Liu Liping Jia Bing Lv Xiaoyun Li Dongmei Chen Yao Yao Dong Qu Daitao Zhang Linqing Zhao | 2024 | Biosafety and Health2024，6，1： | 0 |
| 16 | Measurement of Free and Glucuronidated Cardamonin in Rat Plasma and Bile Using UPLC-MS/MS and Its Application to a Pharmacokinetic and Bile Excretion Study显示文摘A rapid and accurate ultra-high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry(UPLC-MS/MS)method was established and validated for the measurement of two forms of cardamonin,i.e.,free and glucuronidated,in the plasma and bile of rats.Cardamonin and an internal standard(1,8-dihydroxyanthraquinone)were extracted from plasma and bile with ethyl ether via liquid-liquid extraction.The analytes in the extracts were separated by an Agilent Zorbax Stable Bond-C18 column(2.1 mm×50 mm,1.8μm)under isocratic elution conditions[acetonitrile(A)and 0.1%ammonium formate in water(B),40:60(volume ratio)]with a flow rate of 0.4 mL/min,and mass spectrometry in negative ion MRM mode was implemented for analysis.Good linearity over the wide ranges of 0.01–5μg/mL for plasma and 0.025–10μg/mL for bile samples was acquired.Method validation was performed according to the FDA guidelines for bioanalytical methods. | WU Yi JING Runan JIA Guihua WANG Yixiao YU Tianmiao ZHANG Weidong | 2019 | Chemical Research in Chinese Universities2019，35，6： | 0 |
| 17 | Responses of CO_2 in surface water in subtropical West Pacific to El Nio event显示文摘In order to investigate the relationships between the change of T CO 2 , Δ P CO 2 and SST, current, upwelling and biological activities during El Nio event in the subtropical Pacific, the responses of T CO 2 and Δ P CO 2 in surface water in the subtropical Pacific during El Nio and La Nina have been simulated using a three dimension carbon cycle model with biota pump. The results of numerical simulations show that T CO 2 in sea water increases with reducing of SST during mature phase of El Nio in the subtropical West Pacific . At the same period ,the Kuroshio in this region was weakened ,the zonal currents were divergence , the upwelling carried the water with high concentrations of CO 2 to the sea surface , so both of T CO 2 and Δ P CO 2 in surface water were increased . But T CO 2 and Δ P CO 2 were decreased during La Nina period. These simulated results confirmed the observations in 1982/1983 , 1986/1987 , 1991/1995 and 1997/1998 El Nio events . | Xing Runan 1, Ma Liming 2, Qiao Ran 2,Wang Zhanggui 21 .TrainingCenterofChineseMeteorologicalAdministration ,Beijing 10 0 0 81,China2 .NationalResearchCenterforMarineEnvironmentalForecasts ,StateOceanicAdministration ,Beijing 10 0 0 81,China | 2001 | Acta Oceanologica Sinica2001，20，1： | 0 |
| 18 | Tailored amorphous titanium oxide and carbon composites for enhanced pseudocapacitive sodium storage显示文摘As an effective and competitive supplement to the commercialized lithium ion batteries(LIBs),sodium ion batteries(SIBs)have been receiving increasing attention in recent years due to lower cost,richer content,and broader distribution of sodium[1–7].Sodium has similar electrochemical properties to lithium,and thus the concepts for the preparation of electrode materials for SIBs can be borrowed from LIBs[8,9]. | Meng Shao Chengcheng Sun Tianming Chen Ningxiang Wu Runan Zhang Xu Han Yu Shen Peng Wu Wei-Wei Xiong Weina Zhang Sheng Li Fengwei Huo | 2022 | Journal of Energy Chemistry2022，31，2： | 0 |
| 19 | The numerical simulation of Pacific Ocean circulation with five-level model显示文摘A five-level oceanic primitive equation model has been developed. This model is integrated numerically with annual mean wind stress and heat flux at sea surface for 30 a. The ocean circulations tend to quasi-stability. The simulated results show that the computed annual mean currents and sea surface temperature agree well with the observations. | Xing Runan and Chao Jiping Beijing Meteorological College, Beijing 100081 China National Research Center for Marine Environmental Forecasts, Beijing 100081, China | 1993 | Acta Oceanologica Sinica1993，12，3： | 0 |
| 20 | The molecular characteristics of soybean ARR-B transcription factors显示文摘The Type-B authentic response regulator(ARR-Bs)gene family is one of the important plant-specific transcription factor families involved in variety of physiological processes.However,study of ARR-Bs gene family in soybean is limited.Genome-wide analysis and expression profiling of the ARR-Bs gene family were performed in the soybean genome.31 ARR-Bs genes(namely GmARR-B1-31)were identified,containing conserved catalytic domains with protein lengths and molecular weights ranging from 246 to 699 amino acids(aa)and 28.30 to 76.86 kDa,respectively.Phylogenetic analysis grouped ARR-Bs genes into three clusters—Cluster I,Cluster II,and Cluster III—which included 15,12,and 4 genes,respectively,and were asymmetrically distributed on 17 chromosomes.Tissue specific expression analysis of GmARR-Bs family revealed a high transcription level in flowers,roots and seeds.The subcellular localization of GmARR5,GmARR14 were observed in the nucleus,and the promoter region of them included low-temperature responsive element(LTR),the C-repeat/dehydration responsive element(DRE),MBS,ABRE,MYB,MEJA and TCA-elements,which possibly participate in abiotic stress and hormones responses.qRTPCR analysis showed that the expression of GmARR-B genes were affected by different abiotic stresses,especially cold stress and salt stress,and GmARR-B5 and GmARR-B14 were significantly induced by cold stress.This suggested that ARR-Bs genes were involved in multiple abiotic stress response pathways and acted as a positive factor under cold stress. | HE LI RUNAN CHEN ZHONGCHENG CHEN JIAXIN LIN XIJUN JIN CHUNYUAN REN QIUSEN CHEN FENGQIONG CHEN GAOBO YU YUXIAN ZHANG | 2022 | BIOCELL2022，46，6： | 0 |
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