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10篇 您的检索式:作者名="Ruirui Fang"
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1Cerebral fractional amplitude of low-frequency fluctuations may predict headache intensity improvement following acupuncture treatment in migraine patients显示文摘OBJECTIVE:To explore how baseline resting-state cerebral function predicts clinical outcomes of acupuncture treatment for migraine.METHODS:One hundred migraine patients and 46 healthy subjects were recruited.Patients were randomized into the acupuncture,sham acupuncture,and waiting list groups.Resting-state functional magnetic resonance imaging data were collected at baseline and after 1 month of longitudinal acupuncture treatments.Fractional amplitude of low-frequency fluctuations(f ALFF)calculations were applied to explore the associations between baseline f ALFF and changes in clinical variables in the acupuncture treatment group and the waiting list group.RESULTS:Compared with healthy subjects,migraine patients had lower f ALFF in the left rostral ventromedial medulla,right thalamus,left amygdala,and right angular gyrus.Regression analyses revealed that baseline f ALFF values in the left middle frontal gyrus,left superior temporal gyrus,and middle temporal gyrus were positively associated with headache intensity changes in the acupuncture treatment group,while baseline f ALFF values in the bilateral lingual gyrus and cuneus were negatively associated with headache intensity changes in this group.CONCLUSION:The baseline f ALFF values of brain regions associated with cognitive pain modulation,but not migraine severity,may predict future headache intensity improvement levels in migraine patients receiving acupuncture treatment.Li Zhengjie Zhou Jun Cheng Shirui Lan Lei Sun Ruirui Liu Mailan Yang Jie Gao Yujie Guo Taipin Gong Qiyong Zeng Fang Liang Fanrong 2020Journal of Traditional Chinese Medicine2020,40,6:5
2Evolution from small molecule to nano-drug delivery systems:An emerging approach for cancer therapy of ursolic acid显示文摘Ursolic acid(UA),a natural pentacyclic triterpenoid,possesses widespread biological and pharmacological activities.However,drawbacks such as low bioavailability,poor targeting and rapid metabolism greatly hinder its further clinical application.Recently,with the development of nanotechnology,various UA nanosystems have emerged as promising strategies for effective cancer therapy.This article reviews various types of UA-based nanodelivery systems,primarily with emphasis placed on novel UA-based carrier-free nanodrugs,which are considered to be innovative methods for cancer therapy.Moreover,this review presents carrier-free nano-drugs that co-assembled of UA and photosensitizers that displayed synergistic antitumor performance.Finally,the article also describes the development and challenges of UA nanosystems for future research in this field.Overall,the information presented in this review will provide new insight into the rational utilization of nano-drugs in cancer therapy.Jingwei Shao Yifan Fang Ruirui Zhao Fangmin Chen Mingyue Yang Jiali Jiang Zixuan Chen Xiaotian Yuan Lee Jia 2020Asian Journal of Pharmaceutical Sciences2020,15,6:3
3Particulate matter pollution in Kunshan High-Tech zone: Source apportionment with trace elements, plume evolution and its monitoring显示文摘Particulate matter(PM) in the Kunshan High-Tech zone is studied during a three-month campaign. PM and trace elements are measured by the online pollution monitoring, forecastwarning and source term retrieval system AS3. Hourly measured concentrations of PM_(10), PM_(2.5) and 16 trace elements in the PM_(2.5) section(Ca, Pb, Cu, Cl, V, Cr, Fe, Ti, Mn, Ni, Zn, Ga, As, Se, Sr, Ba)are focused. Source apportionment of trace elements by Positive Matrix Factorization modeling indicates that there are five major sources, including dust, industrial processing, traffic,combustion, and sea salt with contribution rate of 23.68%, 21.66%, 14.30%, 22.03%, and 6.89%,respectively. Prediction of plume dispersion from concrete plant and traffic emissions shows that PM_(10) pollution of concrete plant is three orders of magnitude more than that of the traffic. The influence range can extend to more than 3 km in 1 hr. Because the footprint of the industrial plumes is constantly moving according to the local meteorological conditions, the fixed monitoring sites scattered in a few hundred meters haven't captured the heaviest pollution plume at the local scale of a few km^2. As a more intensive monitoring network is not operationally possible, the use of online modeling gives accurate and quantitative information of plume location, which increases the spatial pollution monitoring capacity and improves the understanding of measurement data. These results indicate that the development of the AS3 system, which combines monitoring equipment and air pollution modeling systems, is beneficial to the real-time pollution monitoring in the industrial zone.Suwei Zhang Qijie Zhang Armand Albergel Didier Buty Liangmin Yu Haiting Wang Wuxia Bi Peng Cheng Fu Chen Jun Fang Ruirui Hou Xudong Luan Changgan Shu Jingjing Su 2018Journal of Environmental Sciences2018,30,9:3
4Import of Rift Valley fever to China:a potential new threat?显示文摘Several recent studies in Virologica Sinica and other journals have highlighted the enormous international challenge of emerging arboviral diseases,such as Zika virus disease,dengue,and chikungunya(Islam et al.,2015;Maurice et al.,2015;Dai et al.,2016;Deng et al.,2016;Song et al.,2016;Wang et al.,2016;Xu et al.,2016;Zhang et al.,2016;ZhouXinliang FU Lifang Wang Bo Fang Ruirui Ma Yun Zheng San Huang Pei Zhou Zongxi Cao Jin Tian Shoujun Li Guihong Zhang 2016Virologica Sinica2016,31,5:2
5Boron and nitrogen dual-doped carbon as a novel cathode for high performance hybrid ion capacitors显示文摘Hybrid ion capacitors have been considered as a very attractive energy source with high energy density and power density since it combines both merits of lithium ion batteries and supercapacitors. However,their commercial application has been limited by the mismatch of charge-storage capacity and electrode kinetics between the capacitor-type cathode and battery-type anode. Herein, B and N dual-doped 3D superstructure carbon cathode is prepared through a facile template method. It delivers a high specific capacity, excellent rate capability and good cycling stability due to the B, N dual-doping, which has a profound effect in control the porosity, functional groups, and electronic conductivity for the carbon cathode. The hybrid ion capacitors using B, N dual-doping carbon cathode and prelithiated graphite anode show a high energy density of 115.5 Wh/kg at 250 W/kg and remain about 53.6 Wh/kg even at a high power density of 10 kW/kg. Additionally, the novel hybrid device achieves 76.3% capacity retention after 2000 cycles tested at 1250 W/kg power density. Significantly, the simultaneous manipulation of heteroatoms in carbon materials provides new opportunities to boost the energy and power density for hybrid ion capacitors.Jiangmin Jiang Ping Nie Shan Fang Yadi Zhang Yufeng An Ruirui Fu Hui Dou Xiaogang Zhang 2018Chinese Chemical Letters2018,29,4:1
6Anchoring Group Effects of Surface Ligands on Magnetic Properties of Fe3O4 Nanoparticles: Towards High Performance MRI Contrast Agents显示文摘Jianfeng Zeng Lihong Jing Yi Hou Mingxia Jiao Ruirui Qiao Qiaojuan Jia Chunyan Liu Fang Fang Hao Lei Mingyuan Gao 2014Adv. Mater2014,,17:1
7Influence of Selective Laser Melting Process Parameters on Microstructure and Properties of a Typical Ni-Based Superalloy显示文摘The influence of selective laser melting(SLM)process parameters on the microstructure and mechanical properties of a typical Ni-based superalloy was researched.The optimum parameters of P=170 W,V=0.8 m/s were determined,under which the SLMed samples exhibited both the largest relative density of 99.57%and the best mechanical properties,including the microhardness(329.3±3.8 HV),yield strength(726±8.1 MPa),ultimate tensile strength(900±5.9 MPa)and elongation((31.9±0.24)%).The average grain size ranges of SLMed samples are from 15.2 to 17.4μm,with a typical mixed grain structure.Owing to the high cooling rate and remelting during SLM process,a large number of low-angle grain boundaries(LAGBs),dislocations and sub-grains were formed,and the fraction of LAGBs reached above 65%.At the same time,the content of low-Σcoincidence site lattice(CSL)boundaries was mostly less than 1%,while there was almost noγ′phase precipitated in the matrix.The texture of SLMed samples was weak,and there was no obvious preferred growth direction.Combining with the microstructure characterization,both grain refinement strengthening and dislocation strengthening were considered as the main strengthening mechanisms.Moreover,the fracture mechanism of the optimum sample belonged to ductile fracture.Zhen Lu Chengcai Zhang Nana Deng Haiping Zhou Ruirui Fang Kuidong Gao Yukuo Su Hongbin Zhang 2022Acta Metallurgica Sinica(English Letters)2022,35,10:0
8A reference-grade genome assembly for Astragalus mongholicus and insights into the biosynthesis and high accumulation of triterpenoids and flavonoids in its roots显示文摘Astragalus membranaceus var.mongholicus(AMM),a member of the Leguminosae,is one of the most important medicinal plants worldwide.The dried roots of AMM have a wide range of pharmacological effects and are a traditional Chinese medicine.Here,we report the first chromosome-level reference genome of AMM,comprising nine pseudochromosomes with a total size of 1.47 Gb and 27868 protein-encoding genes.Comparative genomic analysis reveals that AMM has not experienced an independent wholegenome duplication(WGD)event after the WGD event shared by the Papilionoideae species.Analysis of long terminal repeat retrotransposons suggests a recent burst of these elements at approximately 0.13 million years ago,which may explain the large size of the AMM genome.Multiple gene families involved in the biosynthesis of triterpenoids and flavonoids were expanded,and our data indicate that tandemduplication has been the main driver for expansion of these families.Among the expanded families,the phenylalanine ammonia-lyase gene family was primarily expressed in the roots of AMM,suggesting their roles in the biosynthesis of phenylpropanoid compounds.The functional versatility of 2,3-oxidosqualene cyclase genes in cluster Ⅲ may play a critical role in the diversification of triterpenoids in AMM.Our findings provide novel insights into triterpenoid and flavonoid biosynthesis and can facilitate future research on the genetics and medical applications of AMM.Yi Chen Ting Fang He Su Sifei Duan Ruirui Ma Ping Wang Lin Wu Wenbin Sun Qichen Hu Meixia Zhao Lianjun Sun Xuehui Dong 2023Plant Communications2023,4,2:0
9PS-G-GERT Effectiveness Evaluation Model of Link-Based GEO Satellite Communication Constellation under Poor Information Background显示文摘The effectiveness evaluation of GEO satellite communication constellation not only characterizes the communication capability of the constellation but also provides a basis for optimizing the constellation structure.Whether due to information poverty or the complexity of the system,the impact of uncertain information on the effectiveness evaluation needs to be considered to ensure the accuracy of the evaluation results.To address this issue,this paper develops a model for evaluating the GEO satellite communication constellation’s effectiveness in the context of poor information.Firstly,it analyses the GEO satellite communication constellation plus system based on communication links with an in-depth analysis of the constellation structure.Secondly,an equivalent transfer function algorithm based on the characteristic function and transfer probability is proposed with the help of graphical evaluation and review technique.Then,by analyzing the communication link importance connotation,the algorithm formula of communication link effectiveness and its importance is derived,and the constellation effectiveness and variance are found.Finally,the model constructed in this paper is used to evaluate the effectiveness of a GEO satellite communication constellation,further verifying the accuracy and validity of the model.Through comparative analysis,it is shown that the model can not only solving the effectiveness of the constellation but also analyzing the variation of its effectiveness.It lays a theoretical foundation for the analysis and optimization of the GEO satellite communication constellation effectiveness.Ruirui Shao Zhigeng Fang Su Gao Sifeng Liu Weiqing You 2022China Communications2022,19,12:0
10Measurements of Reaction Cross Section and Fragment Momentum Distribution for Proton-rich Nucleus ^31Cl显示文摘Fang Deqing Ma Chunwang Fu Yaoa Ma Yugang Cai Xiangzhou Guo Wei Liu Guihua Shi Yu Tian Wendong Wang Hongwei Fan Ruirui Fu Fen Gao Hui Gao Qi Guo Wentao Han Jianlong Hu Zhengguo Huang Tianhen Jia Fei Lei Xiangguo Li Bo Sun Zhiyu Wang Meng Wang Jiansong Xiao Zhigang Xu Zhiguo Yao Xiangwu Zhang Hongbin Zhang Xueheng Zheng Chuan Xu Hushan Xiao Guoqing Zhan Wenlong 2007近代物理研究所和兰州重离子加速器实验室年报:英文版2007,,1:0
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