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10篇 您的检索式：作者名="Rughetti"

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		题名	作者	年代	出处	被引量
	1	Targeting of macrophage galactose-type C-type lectin (MGL) induces DC sig- naling and activation显示文摘	Napoletano CI Zizzari G Rughetti A	2012	Eur Immunol2012，42，4：	1
	2	MAGE-A and NY-ESO-1 expression in cervical cancer: Prognostic factors and effects of chemotherapy显示文摘	Chiara Napoletano Filippo Bellati Elisabetta Tarquini Federica Tomao Federica Taurino Giulio Spagnoli Aurelia Rughetti Ludovico Muzii Marianna Nuti Pierluigi Benedetti Panici	2008	American Journal of Obstetrics and Gynecology2008，，1：	1
	3	Recombinant tumorassociated MUCI glycoproteinimpairs the differentiation and function of dendritic cells 显示文摘	Rughetti A Pellicciotta I Biffoni M	2005	J Immunol2005，174，12：	1
	4	Regulated expression of MUC1 epithelial antigen in erythropoiesis显示文摘	RUGHETTI A BIFFONI M PIERELLI L	2003	Br J Haematol2003，120，2：	1
	5	Identification of an optimal concentration of platelet gel for promoting angiogenesis in human endothelial cells 显示文摘	Giusi I Rughetti A D'Ascenzo S	2009	Transfusion2009，49，4：	1
	6	Identification of an optimal concentration of platelet gel for promoting angiogenesis in human endothelial cells显示文摘	Giusti I Rughetti A D	2009	Transfusion2009，49，4：	1
	7	Antitumor Immunity Produced by the Liver Kupffer Cells, NK Cells, NKT Cells, and CD8<sup>+</sup> CD122<sup>+</sup> T Cells显示文摘	Shuhji Seki Hiroyuki Nakashima Masahiro Nakashima Manabu Kinoshita Aurelia Rughetti	2011	Clinical and Developmental Immunology2011，，：	1
	8	Recombinant tumor-associated MUCI glyeoprotein impairs the differentiation and function of dendritie cells显示文摘	RUGHETTI A PELLICCIOTTA I BIFFONI M	2005	Immunology2005，174，12：	1
	9	Transfected human dendritic cells to induce antituraor immunity 显示文摘	Rughetti A Biffoni M Sabbatucci M	2000	Gene Ther2000，7，17：	1
	10	HER2-based recombinant immunogen to target DCs through FcγRs for cancer immunotherapy显示文摘Dendritic cell(DC)-based immunotherapy is an attractive approach to induce long lasting antitumor effector cells aiming to control cancer progression. DC targeting is a critical step in the design of DC vaccines in order to optimize delivery and processing of the antigen, and several receptors have been characterized for this purpose. In this study, we employed the FcγRs to target DCs both in vitro and in vivo. We designed a recombinant molecule(HER2- Fc) composed of the immunogenic sequence of the human tumor-associated antigen HER2(aa 364–391) and the Fc domain of a human Ig G1. In a mouse model, HER2-Fc c DNA vaccination activated significant T cell-mediated immune responses towards HER2 peptide epitopes as detected by IFN-γ ELIspot and induced longer tumor latency as compared to Ctrl-Fc-vaccinated control mice. Human in vitro studies indicated that the recombinant HER2-Fc immunogen efficiently targeted human DCs through the FcγRs resulting in protein cross-processing and in the activation of autologous HER2-specific CD8+ T cells from breast cancer patients.	Ilaria Grazia Zizzari Filippo Veglia Federica Taurino Hassan Rahimi Elena Quaglino Francesca Belleudi Federica Riccardo Morena Antonilli Chiara Napoletano Filippo Bellati Pierluigi Benedetti-Panici Maria Rosaria Torrisi Luigi Frati Marianna Nuti Aurelia Rughetti	2015	世界最新医学信息文摘2015，15，5：	0

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