维普中文期刊产品整合服务
211篇 您的检索式:作者名="Rudolf D"
    题名 作者 年代 出处 被引量
1全球生态系统服务与自然资本的价值估算显示文摘编者按:地球上的生态系统是一种复杂的生命支持系统,生态系统对人类的贡献,在生态学研究中经常用“社会效益和经济效益”来表述,是可以用经济价值来估算的。然而,由于其复杂性和不确定性,对这两个效益如何进行估价,一直是困扰生态学家和经济学家的重要问题。Cos...Robert Costanza Ralph d'Arge Rudolf de Groot Stephen Farber Monica Grasso Bruce Hannon Karin Limburg Shahid Naeem Robert V.O'neill Jose Paruelo Robert G.Raskin Paul Sutton Marjan van den Belt 陶大立(译) 1999生态学杂志1999,18,2:38
2The value of the world’s ecosystem services and natural capital显示文摘Robert Costanza Ralph d’Arge Rudolf de Groot Stephen Farber Monica Grasso Bruce Hannon Karin Limburg Shahid Naeem Robert V. O’Neill Jose Paruelo Robert G. Raskin Paul Sutton Marjan van den Belt 1998Ecological Economics1998,,1:4
3The value of the world’s ecosystem services and natural capital显示文摘Robert Costanza Ralph d'Arge Rudolf de Groot Stephen Farber Monica Grasso Bruce Hannon Karin Limburg Shahid Naeem Robert V. O'Neill Jose Paruelo Robert G. Raskin Paul Sutton Marjan van den Belt 1998Ecological Economics1998,,1:2
4Safety,immunogenicity,and protection provided by unadjuvanted and adjuvanted formulations of a recombinant plant-derived virus-like particle vaccine candidate for COVID-19 in nonhuman primates显示文摘Although antivirals are important tools to control severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection,effective vaccines are essential to control the current coronavirus disease 2019(COVID-19)pandemic.Plant-derived virus-like particle(VLP)vaccine candidates have previously demonstrated immunogenicity and efficacy against influenza.Here,we report the immunogenicity and protection induced in rhesus macaques by intramuscular injections of a VLP bearing a SARS-CoV-2 spike protein(CoVLP)vaccine candidate formulated with or without Adjuvant System 03(AS03)or cytidine-phospho-guanosine(CpG)1018.Although a single dose of the unadjuvanted CoVLP vaccine candidate stimulated humoral and cell-mediated immune responses,booster immunization(at 28 days after priming)and adjuvant administration significantly improved both responses,with higher immunogenicity and protection provided by the AS03-adjuvanted CoVLP.Fifteen micrograms of CoVLP adjuvanted with AS03 induced a polyfunctional interleukin-2(IL-2)-driven response and IL-4 expression in CD4 T cells.Animals were challenged by multiple routes(i.e.,intratracheal,intranasal,and ocular)with a total viral dose of 106 plaque-forming units of SARS-CoV-2.Lower viral replication in nasal swabs and bronchoalveolar lavage fluid(BALF)as well as fewer SARS-CoV-2-infected cells and immune cell infiltrates in the lungs concomitant with reduced levels of proinflammatory cytokines and chemotactic factors in the BALF were observed in animals immunized with the CoVLP adjuvanted with AS03.No clinical,pathologic,or virologic evidence of vaccineassociated enhanced disease was observed in vaccinated animals.The CoVLP adjuvanted with AS03 was therefore selected for vaccine development and clinical trials.Stéphane Pillet Prabhu SArunachalam Guadalupe Andreani Nadia Golden Jane Fontenot Pyone Pyone Aye Katharina Röltgen Gabrielle Lehmicke Philipe Gobeil Charlotte Dubé Sonia Trépanier Nathalie Charland Marc-AndréD’Aoust Kasi Russell-Lodrigue Christopher Monjure Robert V.Blair Scott D.Boyd Rudolf P.Bohm Jay Rappaport François Villinger Nathalie Landry Bali Pulendran Brian J.Ward 2022Cellular & Molecular Immunology2022,19,2:2
5The value of ecosystem services:putting the issues in perspective 显示文摘Robert Costanza Ralph d'Arge Rudolf de Groot 1998Ecological Economics1998,25,:1
6The value of the world' s ecosystem services and natural capital显示文摘Costanza R Ralph d' Arge Rudolf de Groot 1997Nature1997,387,:1
7The valve of the world's ecosystem services and natural capital 显示文摘Costanza R Rudolf D de Groot R 1997Nature1997,387,:1
8The value of the world's ecosystem services and natural capital 显示文摘Robert Costanza Ralph d' Arge Rudolf de Groot 1997Nature ( 387)1997,,:1
9The value of the world' s ecosystem services and natural capital 显示文摘Robert Costanza Palph d' Arge Rudolf de Groot 1997Nature1997,386,:1
10Hydrogenolytic Degradation of Thermosets 显示文摘Braun D Gentzkow W Rudolf A P 2001Polym Degrad Stab2001,74,1:1
11The Value of the World's Ecosystem Services and Natural Cap- ital显示文摘Robert Costanza Ralph d' Arge Rudolf de Groot 1997Nature1997,,5:1
12The value of the world's ecosystem services and natural capital显示文摘CONSTANZA R ARGE R d' RUDOLF de GROOT 1997Nature1997,387,:1
13Contaminant concentration and biomarker response in great blue heron eggs from 10 colonies on the upper Missippi River,USA显示文摘Hans Rudolf Buser Markus D Muller 1995Environ Sci Technol1995,29,:1
14The value of the world's ecosystem services and natural capital显示文摘COSTANZA Robert D'ARGE Ralph DE GROOT Rudolf 1997Nature1997,387,:1
15The value of the world's ecosystem services and nature capital显示文摘Robert Costanza Ralph D'Arge Rudolf DE Groot 1997Nature1997,386,:1
16The value of the world' s ecosystem services and natural capital 显示文摘Costanza R d' Arge R Rudolf de Groot 1997Nature1997,,387:1
17Relationship between microstrueture, eytotoxicity and corrosion properties of a Cu-AI-Ni shape memon'y alloy 显示文摘Colic M Rudolf R Stamenkovi6 D 2010Aeta Binmaterialia2010,6,1:1
18The value ofthe world’s ecosystem services and natural capital显示文摘Robert Costanza Ralph d’Arge Rudolf de Groot 1997Nature1997,387,:1
19The value of the world's ecosystem services and natural capital显示文摘 D'arge R Rudolf DE G 1997Nature1997,387,:1
20The value of the world's ecosystem services and natural capital 显示文摘Constanza R d' Arge R Rudolf de Groot 1997Nature1997,387,:1
返回顶部 每页显示:
共11页 首页 上一页 第1页 下一页 末页 /11 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费