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| 1 | 金丝桃素和二甲基亚甲蓝对唑类耐药的白念珠菌菌株的光动力杀菌效应显示文摘背景与目的念珠菌属是普遍存在于哺乳动物和人类皮肤黏膜的微生物。由于念珠菌病复发率很高,唑类真菌药的应用尤为广泛,伴随而来的是高度耐药性。抗微生物光动力治疗(Antimicrobial photodynamic,a PDT)是基于光敏剂联合可见光的一种新兴的抗感染方法。本研究的目的是观察PDT对唑类耐药的白念珠菌菌株的杀真菌效应。 | 周少娜 Paz-Cristobal MP Royo D Rezusta A | 2017 | 中国激光医学杂志2017，26，4： | 3 |
| 2 | Insulin-mimetic compound hexaquis(benzylammonium) decavanadate is antilipolytic in human fat cells显示文摘AIM To assess in rodent and human adipocytes the antilipolytic capacity of hexaquis(benzylammonium) decavanadate(B6V10), previously shown to exert antidiabetic effects in rodent models, such as lowering free fatty acids(FFA) and glucose circulating levels.METHODS Adipose tissue(AT) samples were obtained after informed consent from overweight women undergoing plastic surgery. Comparison of the effects of B6V10 and reference antilipolytic agents(insulin,benzylamine,vanadate) on the lipolytic activity was performed on adipocytes freshly isolated from rat, mouse and human AT. Glycerol release was measured using colorimetric assay as an index of lipolytic activity. The influence of B6V10 and reference agents on glucose transport into human fat cells was determined using the radiolabelled 2-deoxyglucose uptake assay.RESULTS In all the species studied, B6V10 exhibited a dosedependent inhibition of adipocyte lipolysis when triglyceride breakdown was moderately enhanced by β-adrenergic receptor stimulation. B6V10 exerted on human adipocyte a maximal lipolysis inhibition of glycerol release that was stronger than that elicited by insulin. However, B6V10 did not inhibit basal and maximally stimulated lipolysis. When incubated at dose ≥ 10 μmol/L, B6V10 stimulated by twofold the glucose uptake in human fat cells, but-similarly to benzylamine-without reaching the maximal effect of insulin, while it reproduced one-half of the insulin-stimulation of lipogenesis in mouse fat cells. CONCLUSION B6V10 exerts insulin-like actions in adipocytes, including lipolysis inhibition and glucose transport activation. B6V10 may be useful in limiting lipotoxicity related to obesity and insulin resistance. | Christian Carpéné Silvia Garcia-Vicente Marta Serrano Luc Marti ChloéBelles Miriam Royo Jean Galitzky Antonio Zorzano Xavier Testar | 2017 | World Journal of Diabetes2017，8，4： | 2 |
| 3 | Role of minimally invasive surgery in complex adnexal tumours and ovarian cancer显示文摘Ovarian cancer is one of the most common causes of cancer-related death in women. Adnexal masses are frequently diagnosed during reproductive age and often require surgical removal. The risk of malignancy when dealing with a complex adnexal mass should be defined prior to surgery and several scoring systems may be useful for this purpose. Laparoscopic management of ovarian tumours allows a minimally invasive approach with respect to several oncological assumptions. In the last decade concerns have been raised regarding the risk of cyst rupture and tumour spillage as a consequence of the laparoscopic technique itself both in early and advanced stages of ovarian cancer. Although limited data have been reported in the literature on the use of minimally invasive techniques in ovarian cancer, the clear benefits of this approach must be balanced with the potential hazards in different clinical situations. Laparoscopic staging in borderline tumours and presumed early-stage ovarian cancer performed by alaparoscopic oncologist seems to be safe and effective when compared to laparotomy. The precise role of laparoscopy in patients with more advanced cancer is still to be defined, and the risk of suboptimal surgery should never outweigh the potential benefits of minimally invasive surgery. Thus, a tailored prediction of optimal laparoscopic debulking is mandatory in these patients. | Juan Gilabert-Estelles Cristina Aghababyan Paula Garcia Jesus Moscardo Susana Royo Silvana Aniorte Juan Gilabert-Aguilar | 2014 | World Journal of Obstetrics and Gynecology2014，3，3： | 2 |
| 4 | Real-Time PCR for Diagnosing Helicobacter pylori Infection in Patients with Upper Gastrointestinal Bleeding: Comparison with Other Classical Diagnostic Methods显示文摘 | Jesús Saez Sofía Belda Miguel Santibá?ez Juan Carlos Rodríguez Javier Sola-Vera Antonio Galiana Montserrat Ruiz-García Alicia Brotons Elena López-Girona Eva Girona Carlos Sillero Gloria Royo | 2012 | Journal of Clinical Microbiology2012，，10： | 2 |
| 5 | From quantum dots to quantum wires:electronic structyre of semiconductor nanorods显示文摘 | Planelles J Royo R Ballester | 2009 | Phys Rev B2009，80，： | 1 |
| 6 | The value of minilaparotomy for total hysterectomy for benign uterine disease:A comparative study with conventional pfannenstiel and laparoscopic approaches显示文摘 | Royo P A-JL García-Manero Manuel | 2009 | Int Arch Med2009，2，1： | 1 |
| 7 | Structural theory and thermoeconomic diagnosis显示文摘 | Cesar Tones Antonio Valero Luis Serra Javier Royo | 2002 | Energy Conversion and management2002，，： | 1 |
| 8 | Molecular definition of anallelic series of mutations disrupting the myostatin function and cau-sing double muscling in cattle显示文摘 | Grobet L D Poncelet L J Royo B | 1998 | Mammalian Genome1998，9，3： | 1 |
| 9 | Non-nodal typeof mantle cell lymphoma is a specific biological and clinical subgroup of thedis?ease显示文摘 | Royo C Navarro A Clot G | 2012 | Leukemia2012，26，8： | 1 |
| 10 | Are ICTs improving transparency and accountability in the EU regional and local governments? An empirical study 显示文摘 | Pina V Torres L Royo S | 2007 | Public Administration2007，85，3： | 1 |
| 11 | Differences in the expression of the ASIP gene are involved in the recessive black coat colour pattern in sheep: evidence from the rare Xalda sheep breed显示文摘 | Royo L J Alvarez I Arranz J J | 2008 | Animal Genetics2008，39，3： | 1 |
| 12 | Stem cell transplantation as atherapeutic strategy for traumatic brain injury 显示文摘 | Longhi L Zanier ER Royo N | 2005 | Transpl Immunol2005，15，： | 1 |
| 13 | Kinetics and catalyst regeneration by coke combustion I Increased reaction rate due to the presence of chromium 显示文摘 | ROYO C MENENDEZ M SANTAMARIA J | 1991 | React Kinet Catal Lett1991，44，2： | 1 |
| 14 | Molecular definition of an allelic series of mumations disrupting the myostatin function and causing double-muscling in cattle 显示文摘 | Poncelet D Royo L J | 1998 | Mamm Genome1998，9，3： | 1 |
| 15 | The origins of Iberian horses assessed via mitochondrial DNA 显示文摘 | ROYO L J ALVAREZ I BEJA - PEREIRA A | 2005 | J Hered2005，96，6： | 1 |
| 16 | Stem cell transplantation as a therapeutic strategy for traumatic brain injury显示文摘 | Longhi L Zanier ER Royo N | 2005 | Transpl Immunol2005，15，2： | 1 |
| 17 | 1 400W,apotent selective inducible NOS inhibitor,improves histopatho1ogicaI outcome following traumatic brain injury in rats显示文摘 | Jafarian-Tehrani M Louin G Royo NC | 2005 | Nitric Oxide2005，12，： | 1 |
| 18 | 工业4.0时代钢铁行业转型中的新型服务显示文摘伴随着数字化和工业4. 0的快速发展,出现了多种新型的冶金服务模式,并且这些服务模式与中国钢铁行业'十三五'规划制定的转型升级措施相吻合。用3个实例进一步验证了钢铁生产企业要想保持良好的竞争力,与拥有雄厚实力且能提供设备制造、工艺、电气自动化和全方位服务支持的原始设备供应商,建立长期合作、互利共赢的合作关系是十分必要性的。 | Karl Purkarthofer Eva Tatschl-Unterberger Ludwig Reiter Gerald Hohenbichler Klaus Stohl Gabriel Royo | 2019 | 河北冶金2019，，1： | 1 |
| 19 | Patterns of grain filling of spring and winter hexaploid triticales 显示文摘 | Santiveri F Royo C Romagosa I | 2002 | European Journal of Agronomy2002，16，： | 1 |
| 20 | Field screening of barley cultivars to soil salinity using a sprinkler and a drip irrigation system显示文摘 | Isla R Royo A Aragii6s R | 1997 | Plant Soil1997，197，1： | 1 |
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