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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | Steady State plasma- noradrenaline kinetics in quadriplegic chronic spinal cordinjury patients 显示文摘 | Krum H Brown D J Rowe P R | 1990 | J Auton Pharmacol1990，10，4： | 1 |
| 3 | High-temperature refractory metal-intermetallic composites显示文摘 | BEWLAY B P ROWE R G | 1996 | JOM1996，1996，： | 1 |
| 4 | Finite-element modelling of metal flow in three-dimensional forming显示文摘 | HARTLEY P P STURGESS C E N ROWE R W | 1985 | Int J Mach Tool Des Res1985，25，： | 1 |
| 5 | Production of in vitro matured oocytes from 6-week old calves显示文摘 | Earl C R Irvine B J Rowe J P | | 0，，： | 1 |
| 6 | The role of callous and un- emotional traits in the diagnosis of conduct disorder显示文摘 | Rowe R Maughan B Moran P | 2010 | J Child Psychol Psyc2010，51，6： | 1 |
| 7 | High temperature refractory metal intermetallic composites 显示文摘 | JACKSON M R BEWLAY B P ROWE R G | 1996 | JOM1996，48，： | 1 |
| 8 | Predictive value of CallousUnemotional traits in a large community sample显示文摘 | Moran P Rowe R Flach C | | 0，，11： | 1 |
| 9 | Plasticization of aqueous poly(vinyl alcohol)and hydroxypropyl methylcellulose with polyethylene glycols and glycerol显示文摘 | Sakellariou P Hassan A Rowe R | 1994 | European Polymer Journal1994，29，7： | 1 |
| 10 | Evaluation of the hydraulic conductivity of aquitards显示文摘 | Rowe R K Nadarajah P | 1993 | Canadian Geotechnical Journal1993，30，5： | 1 |
| 11 | ACR-ASTRO prac- tice guideline for the performance of therapy with unsealed radio- pharmaceutical sources显示文摘 | Henkin R E Del Rowe J D Grigsby P W | 2011 | Clin Nucl Med2011，36，8： | 1 |
| 12 | High-temperature refractory metal-intermetallic composites显示文摘 | JACKSON M R BEWLAY B P ROWE R G SKELLY D W LIPSITT H A | 1996 | JOM1996，48，1： | 1 |
| 13 | Hightemperature refractory metal-intermetallic composites显示文摘 | BEWLAY B P ROWE R G | 1996 | JOM1996，48，1： | 1 |
| 14 | Plasticization of aqueous poly (vinyl alcohol) and hydroxypropyl methylcellulose with polyethylene glycols and glycerol显示文摘 | Sakellariou P Hassan A Rowe R | 1993 | Eur Polym1993，29，7： | 1 |
| 15 | Isolation and characterization of bergenin derivaves from Macaranga peltata显示文摘 | Ramaiah P A Row L R Reddy D S | 1979 | JCSPerkin 11979，，9： | 1 |
| 16 | Isolation of a cytopathic agent from human adenoids undergoing spontaneous degradation in tissue culture显示文摘 | ROWE W P HUEBNER R J | 1953 | Prnc Soc Exp Biol Med1953，84，： | 1 |
| 17 | Serum 2-hydroxyglutarate levels predict isocitrate dehydrogenase mutations and clinical outcome in acute myeloid leukemia显示文摘 | DiNardo C D Propert K J Loren A W Paietta E Sun Z X Levine R L Straley K S Yen K Patel J P Agresta S Abdel-Wahab O Perl A E Litzow M R Rowe J M Lazarus H M Fernandez H F Margolis D J Tallman M S Luger S M Carroll M | 2012 | Blood2012，121，24： | 1 |
| 18 | Isolation of a cy topathic agent from human adenoids undergoing spontaneous degradation in tissue culture显示文摘 | Rowe W P H uebner R J Gilmore L K et a l | 1953 | Proceedings of the Society for Experimental Biology and Medicine1953，84，： | 1 |
| 19 | A theoretical study of Pile-rock socket behavior Proceedings of International Conference on Structural Foundations on rock显示文摘 | Rowe R K BeUs P J N | 1980 | Sydney1980，，5： | 1 |
| 20 | Efficacy and safety of inhaled insulin (Exubera) compared with subcutaneous insulin therapy in patients with type 2 diabetes:results of a 6-month,randomized,comparative trial显示文摘 | HOLLANDER P A BLONDE L ROWE R | 2004 | Diabetes Care2004，27，10： | 1 |
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