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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | Determination of Enrofloxacin and Ciprofloxacin in Milk Using Molecularly Imprinted Solid - phase Extraction显示文摘 | Yan H Y Tian M L Row K H | 2008 | J Sep Sci2008，31，： | 1 |
| 3 | Localization of mrna for vascular endothelial growth factor (Vegf), angio- poietins and their receptors during the peri-implanta- tion period and early pregnancy in marmosets (Cal- lithrix Jacchus) 显示文摘 | Rowe A J Wulff C Fraser H M | 2003 | Reproduction2003，126，2： | 1 |
| 4 | Evidence-based treatments for acute asthma显示文摘 | ROWE B H EDMONDS M L SPOONER C H | 2001 | Respir Care2001，46，12： | 1 |
| 5 | Operative intervention in delivery is associated with compromised early mother-infant interaction显示文摘 | Rowe M H J Fisher J R | 2001 | British Journal of Obstetrics and Gynaecology2001，108，10： | 1 |
| 6 | Latent membrane protein 1 of Epstein-Barr virus stimulates processing of NF-kappa B2p100 to p52显示文摘 | Atkinson PG Coope H J Rowe M | 2003 | J Biol Chem2003，278，51： | 1 |
| 7 | 显示文摘 | Zou H Rowe D M Min G | 2001 | Journal of Vacuum Sci- ence and Technology A2001，19，3： | 1 |
| 8 | Molecular cloning of polyoma virus DNA in Escherichia coli: plasmid vector system显示文摘 | Israel M A Chan H W Rowe W P | 1979 | Science1979，203，4383： | 1 |
| 9 | Facile Synthesis of Carboxylic Linker on Halofuginone:A Method to Derivatize Haptens Containing both Amine and Hydroxy Functionalities显示文摘 | Rowe L D Beier R C Elissalde M H | 1993 | Synthetic Conmunications1993，23，15： | 1 |
| 10 | Production and Characterization of Monoclonal Antibodies Against the Poultry Coccidiostat Halofuginone显示文摘 | Rowe L D Beier R C Elissalde M H | 1994 | J Agric Food Chem1994，42，： | 1 |
| 11 | High-temperature refractory metal-intermetallic composites显示文摘 | JACKSON M R BEWLAY B P ROWE R G SKELLY D W LIPSITT H A | 1996 | JOM1996，48，1： | 1 |
| 12 | Chiral separation and determination of ofloxacin enantiomers by ionic liquid-assisted ligand-exchange chromatography显示文摘 | Bi W T Tian M L Row K H | 2011 | Analyst2011，136，： | 1 |
| 13 | The effect of deformation on the contact area in grinding 显示文摘 | ROWE W B MORGAN M N QI H S | 1993 | CIRP Annals: Manufacturing Technology1993，42，1： | 1 |
| 14 | MBE growth and properties of ZnO on sapphire and SiC substrates 显示文摘 | Johnson M A L Fujita S Row landW H J | | Electron Mater0，25，5： | 1 |
| 15 | Histone deacetylase inhibitors exhibit anti-inflammatory and neuroprotective effects in a rat permanent ischemic model of stroke : multiple mechanisms of action 显示文摘 | KIM H J ROWE M REN M | 2007 | J Pharmaeol Exp Ther2007，321，3： | 1 |
| 16 | Determination of Enrofloxacin and Ciprofloxacin in Milk Using Molecularly Imprinted Solid - phase Extraction显示文摘 | Yan H Y Tian M L Row K H | 2008 | J Sep Sci2008，31，： | 1 |
| 17 | Serum 2-hydroxyglutarate levels predict isocitrate dehydrogenase mutations and clinical outcome in acute myeloid leukemia显示文摘 | DiNardo C D Propert K J Loren A W Paietta E Sun Z X Levine R L Straley K S Yen K Patel J P Agresta S Abdel-Wahab O Perl A E Litzow M R Rowe J M Lazarus H M Fernandez H F Margolis D J Tallman M S Luger S M Carroll M | 2012 | Blood2012，121，24： | 1 |
| 18 | Molecular cloning of polyoma virus DNA in Escherichia coli:plasmid vector system显示文摘 | Israel M A Chan H W Rowe W P | 1997 | Science1997，203，4383： | 1 |
| 19 | Collagen biomechanics in cerebral arteries and bifurcations assessed by polarizing microscopy显示文摘 | Rowe A J Finlay H M Canham P B | 2003 | J Vasc Res2003，40，4： | 1 |
| 20 | Isolation of mycobacterium paratuberculosis from milk by immunomagnetic separation显示文摘 | GRANT I R BALL H J ROWE M T | 1998 | Appl Environ Microbiol1998，8，64： | 1 |
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