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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | Localization of mrna for vascular endothelial growth factor (Vegf), angio- poietins and their receptors during the peri-implanta- tion period and early pregnancy in marmosets (Cal- lithrix Jacchus) 显示文摘 | Rowe A J Wulff C Fraser H M | 2003 | Reproduction2003，126，2： | 1 |
| 3 | Evidence-based treatments for acute asthma显示文摘 | ROWE B H EDMONDS M L SPOONER C H | 2001 | Respir Care2001，46，12： | 1 |
| 4 | Favorable results with syringosubanachnoid shunts for treatment of syringomyelia显示文摘 | Tator C H Meguro K Rowed D W | 1982 | J Neurosurg1982，56，4： | 1 |
| 5 | Favorable results with sy- ringosubarachnoid shunts for treatment of syringomyelia显示文摘 | Tator C H Meguro K Rowed D W | 1982 | JNeurosurg1982，56，： | 1 |
| 6 | Biochemical networks and epistasis shape the Arabidopsis thaliana metabolome显示文摘 | Rowe H C Hansen B G Halkier B A | 2008 | Plant Cell2008，20，5： | 1 |
| 7 | Facile Synthesis of Carboxylic Linker on Halofuginone:A Method to Derivatize Haptens Containing both Amine and Hydroxy Functionalities显示文摘 | Rowe L D Beier R C Elissalde M H | 1993 | Synthetic Conmunications1993，23，15： | 1 |
| 8 | Production and Characterization of Monoclonal Antibodies Against the Poultry Coccidiostat Halofuginone显示文摘 | Rowe L D Beier R C Elissalde M H | 1994 | J Agric Food Chem1994，42，： | 1 |
| 9 | insulin-like growth factor I regulates type 1 precollagen messenger ribonucleic acid steady state levels in bone of rats显示文摘 | Schmie C H P Guler D Rowe | 1989 | Endocrinology1989，125，： | 1 |
| 10 | Serum 2-hydroxyglutarate levels predict isocitrate dehydrogenase mutations and clinical outcome in acute myeloid leukemia显示文摘 | DiNardo C D Propert K J Loren A W Paietta E Sun Z X Levine R L Straley K S Yen K Patel J P Agresta S Abdel-Wahab O Perl A E Litzow M R Rowe J M Lazarus H M Fernandez H F Margolis D J Tallman M S Luger S M Carroll M | 2012 | Blood2012，121，24： | 1 |
| 11 | Embolotherapy for pelvic congestion syndrome:long-term results显示文摘 | KIM H S MALHOTRA A D ROWE P C | 2006 | J Vasc Interv Radiol2006，17，21： | 1 |
| 12 | Experimental investigation of heat transfer in grinding显示文摘 | Rowe W B Black S C E Qi H S | 1995 | Annals of the CIIIP1995，44，1： | 1 |
| 13 | Prey preference and host suitability of the predatory and parasitoid carabid beetle,Lebia grandis,for several species of Leptinotarsa beetles显示文摘 | WEBERD C ROWELY D L GREENSTONE M H | 2006 | Journal of Insect Science2006，6，： | 1 |
| 14 | Favorable results with syringo-subarachniod shunts for treatment of yringomyelia显示文摘 | Tator C H Meguor K Rowed D W | 1982 | Neurosurg1982，56，4： | 1 |
| 15 | Favorable results with syringosubarachnoid shunts for treatment of syringomyelia显示文摘 | Tator C H Meguro K Rowed D W | 1982 | J Neurosurg1982，56，： | 1 |
| 16 | Automatic P- wave arrival detection and picking with multiscale wavelet analysis for single-componem recordings 显示文摘 | Zhang H J Thurber T Rowe C A | 2003 | Bulletin of the Seismological Society of Ameri- ca2003，93，5： | 1 |
| 17 | When the levee breaks: Treating adolescents and families in the aftermath of Hurricane Katrina 显示文摘 | Rowe C L Liddle H A | 2008 | Journal of Marital and Family Therapy2008，34，2： | 1 |
| 18 | Analysis of expressed sequence tags from multiple Vitis species and development of a compendium of gene expression during berry development显示文摘 | GOES DA SIL V A F IANDOLINO A AL-KAYAL F BOHLMANN M C CUSHMAN M A LIM H ERGULA FIGUEROA R KABULOGLU E K OSBORNE C ROWE J Characterizing the grape transcriptome | 2005 | Plant Physiology2005，139，2： | 1 |
| 19 | Favorable results with syringesubarachnoid shunts for treatment of syringomyelia显示文摘 | Tator C H Megur O K Rowed D W | 1982 | J Neurosurg1982，56，4： | 1 |
| 20 | Automatic P-wave arrival detection and picking with multiscale wavelet analysis for single-component recording显示文摘 | Zhang H J Thurber C Rowe C | 2003 | Bulletin of the Seismological Soiciety of America2003，93，5： | 1 |
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