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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | Localization of mrna for vascular endothelial growth factor (Vegf), angio- poietins and their receptors during the peri-implanta- tion period and early pregnancy in marmosets (Cal- lithrix Jacchus) 显示文摘 | Rowe A J Wulff C Fraser H M | 2003 | Reproduction2003，126，2： | 1 |
| 3 | Production and processing of milk from transgenic goats expressing human lysozyme in the mammary gland 显示文摘 | MAGA E A SHOEMAKER C F ROWE J D | 2006 | Journal of Dairy Science2006，89，2： | 1 |
| 4 | Effects of dietary sodium bicarbonate and calcium chloride on physiological responses of lactating dairy cows in hot weather显示文摘 | ESCOBASA A COPPOCK C E ROWE L D | 1984 | Dairy Sci1984，67，： | 1 |
| 5 | Sequen- tial microarray to identify timing of molecular respon- ses to Haemonchus contortus infection in sheep显示文摘 | ROWE A GONDRO C EMERY D | 2009 | Vet Parasitol2009，161，12： | 1 |
| 6 | Forensic paleontology: The Archaeoraptor forgery显示文摘 | Rowe T Ketcham R A Denison C | 2001 | Nature2001，410，： | 1 |
| 7 | Ultrahigh-vacuum studies of enhanced Raman scattering from pyridine on Ag surfaces显示文摘 | Rowe J E Shank C V Zwemer D A | 1980 | Phys Rev Lett1980，44，： | 1 |
| 8 | A soluble form of Epstein-Barr virus gH/gL inhibits EBV-induced membrane fusion and does not function in fusion显示文摘 | Rowe C L Connolly S A Chen J Jardetzky T S Longnecker R | 2013 | Virology2013，436，1： | 1 |
| 9 | A test of morphological hypotheses for tribal and subtribal relationships of Aphidinae(Insecta:Hemiptera:Aphididae) using DNA seguences显示文摘 | von Dohlen C D Rowe C A Heie O E | | 0，，： | 1 |
| 10 | Biochemical networks and epistasis shape the Arabidopsis thaliana metabolome显示文摘 | Rowe H C Hansen B G Halkier B A | 2008 | Plant Cell2008，20，5： | 1 |
| 11 | Theoretic aspects of chiral separation in capillary electrophoresis 显示文摘 | WREN S A C ROWE R C | 1992 | J Chromatrogr1992，603，： | 1 |
| 12 | Production and processing of milk from transgenic goats expressing human lysozyme in the mammary gland显示文摘 | Maga E A Shoemaker C F Rowe J D | 2006 | J Dairy Sci2006，89，2： | 1 |
| 13 | Design, synthesis and evaluation of furanocoumarin monomers as inhibitors of CYP3A4 显示文摘 | ROW E C BROWN S A STACHULSKI A V | 2006 | Org Biomol Chem2006，4，10： | 1 |
| 14 | Plasma-enhanced a- tomic layer deposition of anatase TiO2 using TIC14 显示文摘 | Kubala N G Row Wolden C A | 2009 | J Phys Chem C2009，113，16： | 1 |
| 15 | Serum 2-hydroxyglutarate levels predict isocitrate dehydrogenase mutations and clinical outcome in acute myeloid leukemia显示文摘 | DiNardo C D Propert K J Loren A W Paietta E Sun Z X Levine R L Straley K S Yen K Patel J P Agresta S Abdel-Wahab O Perl A E Litzow M R Rowe J M Lazarus H M Fernandez H F Margolis D J Tallman M S Luger S M Carroll M | 2012 | Blood2012，121，24： | 1 |
| 16 | Embolotherapy for pelvic congestion syndrome:long-term results显示文摘 | KIM H S MALHOTRA A D ROWE P C | 2006 | J Vasc Interv Radiol2006，17，21： | 1 |
| 17 | A distinct lineage of influenza A virus from bats显示文摘 | Tong S Li Y Rivailler P Conrardy C Castillo D A Chen L M Recuenco S Ellison J A Davis C T York I A Turmelle A S Moran D Rogers S Shi M Tao Y Weil M R Tang K Rowe L A Sammons S Xu X Frace M Lindblade K A Cox N J Anderson L J Rupprecht C E Donis R O | 2012 | PANS2012，109，11： | 1 |
| 18 | “Theory of mind” Impairments and Their Relationship to Executive Functioning Following Frontal Lobe Excisions 显示文摘 | Rowe A D Bullock P R Polkey C E | 2001 | Brain2001，124，： | 1 |
| 19 | Effects of dietary sodium bicarbonate and calcium chloride on physiological responses of lactating dairy cows in hot weather显示文摘 | Escobosa A Coppock C E Rowe L D | 1984 | J Dairy Sci1984，67，： | 1 |
| 20 | Bacterial lysis ofAureococcus anophagefferens CCMP 1784 ( Pelagophyceae) 显示文摘 | FRAZIER A D ROWE J M RENTZ C A | 2007 | Journal of Phycology2007，43，46： | 1 |
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