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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | Production and processing of milk from transgenic goats expressing human lysozyme in the mammary gland 显示文摘 | MAGA E A SHOEMAKER C F ROWE J D | 2006 | Journal of Dairy Science2006，89，2： | 1 |
| 3 | Effects of dietary sodium bicarbonate and calcium chloride on physiological responses of lactating dairy cows in hot weather显示文摘 | ESCOBASA A COPPOCK C E ROWE L D | 1984 | Dairy Sci1984，67，： | 1 |
| 4 | Sequen- tial microarray to identify timing of molecular respon- ses to Haemonchus contortus infection in sheep显示文摘 | ROWE A GONDRO C EMERY D | 2009 | Vet Parasitol2009，161，12： | 1 |
| 5 | Ultrahigh-vacuum studies of enhanced Raman scattering from pyridine on Ag surfaces显示文摘 | Rowe J E Shank C V Zwemer D A | 1980 | Phys Rev Lett1980，44，： | 1 |
| 6 | Electrical transport properties of SnBi4Te7 and PbBi4Te7 with different deviations from stoichiometry显示文摘 | Kuznetsov V L Kuznetsova L A ROWE D M | | 0，，： | 1 |
| 7 | A test of morphological hypotheses for tribal and subtribal relationships of Aphidinae(Insecta:Hemiptera:Aphididae) using DNA seguences显示文摘 | von Dohlen C D Rowe C A Heie O E | | 0，，： | 1 |
| 8 | The effects of infiltr-ation on the stability of a dry ash dump显示文摘 | FOURIE A B ROWE D BLIGHT G H | 1999 | Gé otechnique1999，49，1： | 1 |
| 9 | Seven polymorphic microsatellite loci in honeybees (Apis mellifera) 显示文摘 | ROWE D J RINDERER T E STELZER J A | 1997 | Insectes-Soc iaux1997，44，2： | 1 |
| 10 | Value Orientations, Awareness of Consequences, and Participation in a Whale Watching Education Program in Oregon 显示文摘 | Christensen A Rowe S Needham M D | 2007 | Human Dimensions of Wildlife2007，12，4： | 1 |
| 11 | Is the current BMI obesity classification appropriate for black and white post- menopausal women? 显示文摘 | EVANS E M ROWE D A GACETTE S B etal | 2006 | Int J Obes (Lond)2006，30，5： | 1 |
| 12 | High-temperature refractory metal-intermetallic composites显示文摘 | JACKSON M R BEWLAY B P ROWE R G SKELLY D W LIPSITT H A | 1996 | JOM1996，48，1： | 1 |
| 13 | Isolation and characterization of bergenin derivaves from Macaranga peltata显示文摘 | Ramaiah P A Row L R Reddy D S | 1979 | JCSPerkin 11979，，9： | 1 |
| 14 | Production and processing of milk from transgenic goats expressing human lysozyme in the mammary gland显示文摘 | Maga E A Shoemaker C F Rowe J D | 2006 | J Dairy Sci2006，89，2： | 1 |
| 15 | Exploiting temperature dependency in the detection of NQR signals显示文摘 | JAKOBSSON A MOSSBERG M ROWE M D | 2006 | IEEE Transactions on Signal Processing2006，54，5： | 1 |
| 16 | Mechanisms of pathogenicity of influenza A (H5N1) viruses in mice显示文摘 | Bright R A Cho D S Rowe T | 2003 | Avian Dis2003，47，3： | 1 |
| 17 | Mechanisms of pathogenicity of influenza A(H5N1) viruses in mice显示文摘 | Bright R A Cho D S Rowe T | 2003 | Avian Dis2003，47，3： | 1 |
| 18 | Robust detection of stochastic nuclear quadrupole resonance signals 显示文摘 | SOMASUNDARAM S D JAKOBSSON A ROWE M D | 2008 | IEEE Transactions on Signal Processing2008，56，9： | 1 |
| 19 | Serum 2-hydroxyglutarate levels predict isocitrate dehydrogenase mutations and clinical outcome in acute myeloid leukemia显示文摘 | DiNardo C D Propert K J Loren A W Paietta E Sun Z X Levine R L Straley K S Yen K Patel J P Agresta S Abdel-Wahab O Perl A E Litzow M R Rowe J M Lazarus H M Fernandez H F Margolis D J Tallman M S Luger S M Carroll M | 2012 | Blood2012，121，24： | 1 |
| 20 | Bacterial resistance evolution by recruitment of super - integron gene cassettes 显示文摘 | ROWE MAGNUS D A GUEROUT A M MAZEL D | 2002 | Mol Microbiol2002，43，6： | 1 |
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