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2篇 您的检索式：作者名="Rotonya Carr"

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		题名	作者	年代	出处	被引量
	1	Experimental models of metabolic and alcoholic fatty liver disease显示文摘Non-alcoholic fatty liver disease(NAFLD)is a multi-systemic disease that is considered the hepatic manifestation of metabolic syndrome(MetS).Because alcohol consumption in NAFLD patients is common,there is a significant overlap in the pathogenesis of NAFLD and alcoholic liver disease(ALD).Indeed,MetS also significantly contributes to liver injury in ALD patients.This“syndrome of metabolic and alcoholic steatohepatitis”(SMASH)is thus expected to be a more prevalent presentation in liver patients,as the obesity epidemic continues.Several pre-clinical experimental models that couple alcohol consumption with NAFLDinducing diet or genetic obesity have been developed to better understand the pathogenic mechanisms of SMASH.These models indicate that concomitant MetS and alcohol contribute to lipid dysregulation,oxidative stress,and the induction of innate immune response.There are significant limitations in the applicability of these models to human disease,such as the ability to induce advanced liver injury or replicate patterns in human food/alcohol consumption.Thus,there remains a need to develop models that accurately replicate patterns of obesogenic diet and alcohol consumption in SMASH patients.	Delfin Gerard Buyco Jasmin Martin Sookyoung Jeon Royce Hooks Chelsea Lin Rotonya Carr	2021	World Journal of Gastroenterology2021，27，1：	2
	2	Temporal Effects of Ethanol Consumption on Energy Homeostasis, Hepatic Steatosis, and Insulin Sensitivity in Mice显示文摘	Rotonya M. Carr Ravi Dhir Xiaoyan Yin Beamon Agarwal Rexford S. Ahima	2013	Alcohol Clin Exp Res2013，，7：	1

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