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| 1 | The Genome of Artemisia annua Provides Insight into the Evolution of Asteraceae Family and Artemisinin Biosynthesis显示文摘Artemisia annua,通常已知的同样香甜的苦恼或 Qinghao,是到中国的一个灌木土著人并且长被用于药用的目的。A。annua 现在作为有势力抗疟药混合物的唯一的生来的来源全球性被栽培, artemisinin。这里,我们报导 A 的 1.74-gigabase 染色体的一个高质量的草稿集会。annua,高度异质接合,富于重复定序,并且包含 63 ? 226 编码蛋白质的基因,在定序的植物种类之中的最大的数字之一。我们发现了那,作为在 Asteraceae 的一些定序的染色体之一, A。annua 染色体包含对这大被子植物 clade 特定的很多基因。尤其是,扩大和编码涉及萜烯生合成的酶的基因的功能的多样化与 artemisinin biosynthetic 小径的进化一致。我们进一步由介绍那 A 的 transcriptome 揭示了。annua 发展了复杂 transcriptional 规章的网络位于 \O 下面 artemisinin 生合成。把转基因的 A 基于我们产生了的全面 genomic 和 transcriptomic 分析。artemisinin 高级的生产的 annua 线,它现在为大规模生产准备好了并且将从而帮助遇见增加 artemisinin 的全球需求的挑战。 | Qian Shen Lida Zhang Zhihua Liao Shengyue Wang Tingxiang Yan Pu Shi Meng Liu Xueqing Fu Qifang Pan Yuliang Wang Zongyou Lv Xu Lu Fangyuan Zhang Weimin Jiang Yanan Ma Minghui Chen Xiaolong Hao Ling Li Yueli Tang Gang Lv Yan Zhou Xiaofen Sun Peter E. Brodelius Jocelyn K.C. Rose Kexuan Tang | 2018 | Molecular Plant2018，11，6： | 47 |
| 2 | Blood levels and serum protein binding of cis-platinum (Ⅱ) complexed to carboxymethyl-dextran显示文摘 | Schechter B Rosing MA Wilchek M | 1989 | Cancer Chemother Pharmacol1989，24，： | 1 |
| 3 | Advances in drop wise condensation heat transfer: Chinese research 显示文摘 | MA Xuehu ROSE J W XU Dunqi | 2000 | Chemical Engineering Journal2000，78，1： | 1 |
| 4 | Prospective mem- ory in Parkinson disease during a virtual week: effects of both prospective and retrospective demands显示文摘 | Foster ER Rose NS McDaniel MA | 2013 | Neuropsychol- ogy2013，27，2： | 1 |
| 5 | The effectiveness of deep placement of fertilisers is determined by crop species and edaphic conditions in Mediterranean-type environments: a review显示文摘 | Ma Q Rengel Z Rose T | 2009 | Australia Journal of Soil Research2009，，47： | 1 |
| 6 | Conservative surgery and radiation therapy for early breast cancer显示文摘 | Olivotto I Cady B | 1989 | Arch Surg1989，124，2： | 1 |
| 7 | Gabapentin:pharmacology and its use in pain management显示文摘 | Rose MA Kam PC | 2002 | Anaesthesia2002，57，： | 1 |
| 8 | Synthetic dsRNA Dicer substrate enhance RNAi potency and efficiency显示文摘 | Kim DH Behlke MA Rose SD | 2005 | Nat Biotechnol2005，23，2： | 1 |
| 9 | Cultured pressure ulcer flbroblasts show replicative senescence with elevated production of plasmin, plasminogen activator inhibitor-l,and transforming growth factor-betal 显示文摘 | Vande Berg JS Rose MA Haywood-Reid PL etal | 2005 | Wound Repair Regen2005，13，1： | 1 |
| 10 | Interleukin-lbeta modulates proinflammatory cytokine production in human epithelial cells显示文摘 | Eskan MA Benakanakere MR Rose BG | 2008 | Infect lmmun2008，76，5： | 1 |
| 11 | Interleukin -1 beta modulates proinflammatnry cytokine production in human epithelial cells 显示文摘 | Eskan MA Benakanakere MR Rose BG | 2008 | Infect Immun2008，76，5： | 1 |
| 12 | Heat transfer and pressure drop char- acteristics for condensation of R113 in a vertical micro-finned tube with wire insert 显示文摘 | Ma X H Briggs A Rose J W | 2004 | International Communications in Heat and Mass Transfer2004，31，： | 1 |
| 13 | Advances in dropwise condensation heat transfer: Chinese Research显示文摘 | MA XUEHU ROSE J W | 2000 | Chemical Enginnering Journal2000，78，1： | 1 |
| 14 | Phase Ⅱ evaluation of pacli- taxel and carboplatin in the treatment of carcinosarcoma of the uterus: a Gynecologic Oncology Group study 显示文摘 | Powell MA Filiaci VL Rose PG | 2010 | J Clin Oncol2010，28，16： | 1 |
| 15 | Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy 显示文摘 | KIM DH BEHLKE MA ROSE SD | 2005 | Nature Bio- technology2005，23，： | 1 |
| 16 | Chemical modification patterns compatible with high potency dicer-substrate smaU interfering RNAs 显示文摘 | Collingwood MA Rose SD Huanq L | 2005 | Oligonucleotides2005，18，2： | 1 |
| 17 | Phase Ⅱ trial of external beam radiation with etanidazole (SR-2508) for the treatment of locally advanced prostate cancer 显示文摘 | Beard C 13uswell L Rose MA | 1994 | Int J Radiat Oncol Biol Phys1994，29，3： | 1 |
| 18 | Gabapentin: pharmacology and it s use in pain management显示文摘 | Rose MA Kam PC | 2002 | Anaesthesia2002，57，： | 1 |
| 19 | Gabapentin:Pharmacologyand its use in pain management显示文摘 | Rose MA Kam PC | 2002 | Anesthesia2002，57，5： | 1 |
| 20 | Gabapentin: Pharmacology and its use in pain management显示文摘 | Rose MA Kam PC | 2002 | Anesthesia2002，57，5： | 1 |
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