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| 1 | 脐带血铅含量与婴儿神经行为发育的关系显示文摘为了探讨儿童铅中毒的诊断标准,作者选择132名婴儿,以其脐血铅水平作为铅暴露示标,3月龄时在蓓蕾(Bayley)婴儿发育量表上的精神发育指数(MDI)和心理运动发育指数(PDI)为效应示标,研究铅对婴儿神经发育的影响。结果血铅≥0.48μmol/L的婴儿其MDI和PDI均明显落后于血铅<0.48μmol/L者。若分别以血铅为0.72、0.48和0.24μmol/L为分界线,将所有婴儿分为高铅组和相对低铅组,发现随着分界线的下移,两组间MDI和PDI的差别渐趋缩小,当分界线为0.24μmol/L时,高低铅组间MDI和PDI的统计学差异不复存在。据此,作者建议,我国宜采纳血铅≥0.48μmol/L作为儿童铅中毒的诊断标准。 | 沈晓明 颜崇淮 周建德 敖黎明 李纫秋 黄红 郭迪 吴圣楣 John Rosen | 1996 | 中华预防医学杂志1996，30，2： | 41 |
| 2 | 狼逼门前:1994~2000的好莱坞和中国电影市场(上)显示文摘 | 斯坦利.罗森(Stanley Rosen) 戚锰 钟静宁 龚湘凌 | 2003 | 北京电影学院学报2003，，1： | 18 |
| 3 | 低水平铅暴露对早期婴儿发育的影响显示文摘为了研究出生前后低水平铅暴露对儿童发育的影响,前瞻性观察了102例出生时血铅在0.10~0.84μmol/L低水平铅暴露婴儿的发育,通过多因素统计评价其因果关系。结果发现,即使在这个以往完全被认为是正常的铅暴露范围内,脐血血铅水平与3个月时在Bayley发育量表上的精神发育指数(MDI)和心理运动发育指数(PDI)有明确的负相关关系。血铅≥0.48μmol/L的婴儿在3月龄时的MDI和PDI明显低于血铅水平<0.48μmol/L者,分别相差4.6和8.8分,差异有非常显著意义(P<0.01)。经多元逐步回归分析和多元协方差分析,结果提示这种差异依然存在。提示儿童血铅水平≥0.48μmol/L时确能对其早期发育产生不利影响。 | 沈晓明 颜崇淮 周建德 敖黎明 李纫秋 黄红 郭迪 吴圣楣 John Rosen | 1996 | 中华儿科杂志1996，34，4： | 17 |
| 4 | Visceral hypersensitivity and electromechanical dysfunction as therapeutic targets in pediatric functional dyspepsia显示文摘Functional gastrointestinal disorders(FGID) are common clinical syndromes diagnosed in the absence of biochemical,structural,or metabolic abnormalities. They account for significant morbidity and health care expenditures and are identifiable across variable age,geography,and culture. Etiology of abdominal pain associated FGIDs,including functional dyspepsia(FD),remains incompletely understood,but growing evidence implicates the importance of visceral hypersensitivity and electromechanical dysfunction. This manuscript explores data supporting the role of visceral hypersensitivity and electromechanical dysfunction in FD,with focus on pediatric data when available,and provides a summary of potential therapeutic targets. | John M Rosen Jose T Cocjin Jennifer V Schurman Jennifer M Colombo Craig A Friesen | 2014 | World Journal of Gastrointestinal Pharmacology and Therapeutics2014，5，3： | 16 |
| 5 | 基于A位元素置换策略合成新型MAX相材料Ti_3ZnC_2显示文摘MAX相材料是一类兼具金属和陶瓷特性的三元层状材料,在高温导电、耐磨、耐腐蚀和耐辐照损伤等方面性能优异。目前已经合成出的MAX相材料已有70余种,但A位元素一直局限在ⅢA和ⅣA主族元素,如Al、Si、Ga等,而以副族元素占据A位的MAX相鲜有报道。本研究以Ti_3AlC_2为前驱体,利用熔盐中的A位置换反应,制备出了A位为Zn元素的全新MAX相材料Ti_3ZnC_2。结合X射线衍射、扫描电子显微镜和透射电子显微镜等分析手段对Ti_3ZnC_2的成分和结构进行了确认,并通过密度泛函理论对Ti_3ZnC_2的结构稳定性和晶格参数进行了确定。进一步通过热力学计算对Fe、Co、Ni、Cu等几种元素的A位置换反应进行了预测,发现采用这几种元素的氧化物进行置换反应在热力学上也都具有可行性。本研究所提出的元素置换策略是在保持MAX相六方层状晶体结构的基础上,利用Al、Zn在高温下形成共晶产物实现Zn原子向A层内的迁移,而熔盐介质的存在促进了反应动力学。本方法巧妙地避免了MAX相传统合成过程中竞争相的形成,如M-A合金相,因此可以用于探索更多未知的MAX相材料。 | 李勉 李友兵 罗侃 LU Jun EKLUND Per PERSSON Per ROSEN Johanna HULTMAN Lars 都时禹 黄政仁 黄庆 | 2019 | 无机材料学报2019，34，1： | 14 |
| 6 | 用值来综合评估燃煤锅炉排放烟气污染程度的可行性显示文摘目的用一个参数值来评估一个大型燃煤锅炉所排放烟气中温度和化学物(SO2、NO、CO2)各自和综合污染分布特性,简化实际污染评估手段.方法通过数学模拟的方法建立大型锅炉烟气排放分析模型、建立排放烟气的温度分布、质量浓度分布、分布数学模型,并把所得的3种分布结果及特性进行比较.结果给出锅炉烟气排放分析模型中烟气的温度污染和主要排放物CO2,SO2,NO2的化学污染的火用值在排放高度、离地10m高度、和地面上沿风向分布的轴向模拟分析曲线、烟气的温度和主要排放物的浓度的分布曲线;找出烟气在3个不同高度污染的特点、污染的最严重地点,检查总污染的火用指标与各污染物单独评价指标的异同.结论得出仅用参数值作为污染评估值来评估排放烟气污染是完全可行的,而且充分显示了一个能联系不同自然学科,并在不同学科中自由转换的参数值火用作为污染评估标准的优越性.即可以把不同污染物的污染特性综合起来,集复杂的多种评估参数为一体,简化评估手段和方法,易于找到多种污染的最不利点. | 敖永安 Marc A Rosen | 2005 | 沈阳建筑大学学报(自然科学版)2005，21，3： | 9 |
| 7 | Management of low transsphincteric anal fistula with serial setons and interval muscle-cutting fistulotomy显示文摘This study evaluates low transsphincteric anal fistula managed by serial setons and interval fistulotomy, with attention to healing without recurrence and preservation of continence. Following Institutional Review Board approval, consecutive anal fistula operations performed by a single surgeon from January 1, 2009 to December 31, 2013 were retrospectively reviewed using electronic medical records and telephone interviews for patients lost to follow up. Of the 71 patients, 26(37%) had low transsphincteric fistula(23 males and 3 females; mean age: 46 years), treated at our institution by seton placement followed by interval surgical muscle cutting and subsequent seton replacement or final fistulotomy. Of the 26 patients, 22(85%) were initially referred due to previous failed treatment, with a 30.6 month mean duration of fistula prior to referral and a mean of 2.2(range: 0–6) prior anorectal surgeries. At a mean follow-up of 11.9 months, none of the 21 patients experienced recurrence or fecal incontinence. Serial seton with interval muscle-cutting sphincterotomy followed by complete fistulotomy is an effective treatment for the management of patients who are either initially seen for low transsphincteric fistula, or referred after failed anorectal surgery for that condition. | Chen Wang Lester Rosen | 2016 | Journal of Integrative Medicine2016，14，2： | 7 |
| 8 | 开关模式LED驱动器的调光技术显示文摘线性电流源由于其耗电性而不再被节能意识日益增强的世界所接受,开关模式的LED驱动器早已取代其成为现今的标准。此处描述的是LED的一些基本理论,以及用于为开关模式LED驱动器提供调光控制的多种技术。 | Rich Rosen | 2009 | 电子产品世界2009，16，10： | 7 |
| 9 | Fault diagnosis model based on multi-manifold learning and PSO-SVM for machinery显示文摘Fault diagnosis technology plays an important role in the industries due to the emergency fault of a machine could bring the heavy lost for the people and the company. A fault diagnosis model based on multi-manifold learning and particle swarm optimization support vector machine(PSO-SVM) is studied. This fault diagnosis model is used for a rolling bearing experimental of three kinds faults. The results are verified that this model based on multi-manifold learning and PSO-SVM is good at the fault sensitive features acquisition with effective accuracy. | Wang Hongjun Xu Xiaoli Rosen B G | 2014 | 仪器仪表学报2014，35，S2： | 6 |
| 10 | Evaluating the management of anaphylaxis in US emergency departments:Guidelines vs.practice显示文摘BACKGROUND:Anaphylaxis is characterized by acute episodes of potentially life-threatening symptoms that are often treated in the emergency setting.Current guidelines recommend:1) quick diagnosis using standard criteria;2) first-line treatment with epinephrine;and 3) discharge with a prescription for an epinephrine auto-injector,written instructions regarding long-term management,and a referral(preferably,allergy) for follow-up.However,studies suggest low concordance with guideline recommendations by emergency medicine(EM) providers.The study aimed to evaluate how emergency departments(EDs) in the United States(US) manage anaphylaxis in relation to guideline recommendations.METHODS:This was an online anonymous survey of a random sample of EM health providers in US EDs.RESULTS:Data analysis included 207 EM providers.For respondent EDs,approximately 9%reported using agreed-upon clinical criteria to diagnose anaphylaxis;42%reported administering epinephrine in the ED for most anaphylaxis episodes;and <50%provided patients with a prescription for an epinephrine auto-injector and/or an allergist referral on discharge.Most provided some written materials,and follow-up with a primary care clinician was recommended.CONCLUSIONS:This is the first cross-sectional survey to provide 'real-world' data showing that practice in US EDs is discordant with current guideline recommendations for the diagnosis,treatment,and follow-up of patients with anaphylaxis.The primary gaps are low(or no) utilization of standard criteria for defining anaphylaxis and inconsistent use of epinephrine.Prospective research is recommended. | W.Scott Russell Judith Rosen Farrar Richard Nowak Daniel P.Hays Natalie Schmitz Joseph Wood Judi Miller | 2013 | World Journal of Emergency Medicine2013，4，2： | 4 |
| 11 | 在心前区导联用T波向量方向鉴别起搏后与缺血性T波倒置 | Shvilkin A. Ho K.K.L. Rosen M.R. Josephson M.E. 刘文秀 | 2005 | 世界核心医学期刊文摘(心脏病学分册)2005，0，8： | 4 |
| 12 | Targeted cancer therapies显示文摘With unprecedented understanding of molecular events underlying human cancer in this genomic era, a large number of drugs specifically targeting hypothesized oncogenic drivers to which tumors are potentially addicted to have been developed and continue to be developed. These targeted cancer therapies are being actively tested in clinical trials with mixed successes. This editorial provides an overview on successful targeted cancer drugs on the market and those drugs that are in late clinical development stages. Importantly, the article lays out main challenges in developing molecular targeted therapies and potential path forward to overcome these challenges, as well as opportunities for China in this new era of targeted agents. The editorial serves as an introduction to the Targeted Cancer Therapies series that will review in depth of major pathways and drugs targeting these pathways to be published in the coming issues of the Chinese Journal of Cancer. | Li Yan Neal Rosen Carlos Arteaga | 2011 | Chinese Journal of Cancer2011，30，1： | 3 |
| 13 | Physiological and pharmacological basis for the ergogenic effects of growth hormone in elite sports显示文摘生长荷尔蒙(GH ) 是在前面的垂体从房间在一个脉动的模式被分泌的重要、强大的新陈代谢的荷尔蒙,由几正常和 pathophysiological 条件影响了。人的 GH 首先在 1950 年代被孤立,人的导出的 cadaveric GH 开始被用来与 GH 缺乏对待病人。然而,自从 mid-1980s 和这 recombinant GH 的来临作为一个做的代理人增加了 GH 的滥用,合成 recombinant GH 是广泛地可得到的。与 GH 做是在精英运动员之中并且在在体育馆训练的人之中的一个著名问题,但是为医药、道德的原因被禁止。它主要是 anabolism 并且到某程度,被它的用户珍视的 GH 的分解脂肪的效果。尽管 GH 作为在运动员之中的有效的因此遗传因子的药是谣言, GH 的有效性在最后几年期间作为一个单个做代理人被询问了。有科学证据的缺乏在在上的那 GH 生理的剂量除那些以外的肌肉锻练性能上的另外的效果从训练优化和食谱本身获得了。然而,如果 GH 与被相结合,可能有 synergistic 效果,例如 anabolism 的类固醇,和 GH 似乎穿上积极效果骨胶原合成。不管是否做的 GH 是有效的,有需要让一个可靠测试方法检测做的 GH。几个问题为检测复杂的做的 GH 做了一个方法的发展,但是一个方法在雅典和 Turin 在奥林匹克被介绍了并且使用。有方法的一个问题使用了,在测试能有效地揭示哪个做期间从最后 GH 管理是短时间跨度(24 36 个小时) 。因此,测试的 out-of-competition 将是关键的。然而,与不同途径工作开发其他的、可靠测试是进行中的。 | Christer Ehrnborg Thord Rosen | 2008 | Asian Journal of Andrology2008，10，3： | 3 |
| 14 | The European registry of quality outcomes for cataract and refractive surgery(EUREQUO):a database study of trends in volumes,surgical techniques and outcomes of refractive surgery显示文摘Background:A European web-based registry for refractive surgery was established in 2008;The European Registry of Quality Outcomes for Cataract and Refractive Surgery(EUREQUO).The aim of the registry was to improve treatment and standards of care for refractive surgery.Further aims were to offer a tool for benchmarking by establishing a reference database and for surgeons to enter and analyze their own outcomes.The purpose of this study was to characterize the registry and analyze the data collected during its first decade.Methods:The characteristics of the web-based registry are described.Data collected from February 4^(th) 2004 until June 30th 2014 are included in the analysis.The database is analyzed in terms of surgical technique,indications for surgery,complications,and refractive and visual outcomes.Results:Data have been reported from 47 centers in 14 countries until mid-2014.About 4,000 procedures were reported annually.The most frequent procedure was laser-assisted in-situ keratomileusis(LASIK)with 11697 reported surgeries.Over time in the database,LASIK declined(p<0.001)while photorefractive keratectomy(PRK)and refractive lens exchange(RLE)increased(p<0.001 for both procedures).The indications for surgery,in terms of preoperative refraction and age,were stable over time,for all types of procedures.Surgical complications were reported infrequently and with a well-known relationship to the type of surgical procedure.The reported refractive outcomes were good.The visual outcomes indicate a significant increase of visual acuity after high myopia treatment by phakic intraocular lens in the anterior(phakic IOL AC)and the posterior(phakic IOL PC)chamber and a poorer visual outcome,after both myopia and hyperopia treatment,by epithelial LASIK(Epi-LASIK).Conclusions:We describe the establishment of a European registry for refractive surgery.The database increases at a rate of approximately 4000 refractive procedures per year.The most frequent procedure is LASIK,but both PRK and RLE are an increasing part of the reported procedures.The indications for surgery have been stable over time.Surgical complications and visual outcome vary,depending on the type of surgery. | Mats Lundström Sonia Manning Peter Barry Ulf Stenevi Ype Henry Paul Rosen | 2015 | Eye and Vision2015，2，1： | 3 |
| 15 | Epithelial-Mesenchymal Transition (EMT) in Tumor-Initiating Cells and Its Clinical Implications in Breast Cancer显示文摘 | Chad J. Creighton Jenny C. Chang Jeffrey M. Rosen | 2010 | Journal of Mammary Gland Biology and Neoplasia2010，，： | 3 |
| 16 | Mathematical modelling of translational motion of rail-guided cart with suspended payload显示文摘In this paper modelling of the translational motion of transportation rail-guided cart with rope suspended payload is considered. The linearly moving cart,driven by a travel mechanism,is modelled as a discrete six degrees of freedom (DOF) dynamic system. The hoisting mechanism for lowering and lifting the payload is considered and is included in the dynamic model as one DOF system. Differential equations of motion of the cart elements are derived using Lagrangian dynamics and are solved for a set of real-life constant parameters of the cart. A two-sided interaction was observed between the swinging payload and the travel mechanism. Results for kinematical and force parameters of the system are obtained. A verification of the proposed model was conducted. | MITREV Rosen | 2007 | Journal of Zhejiang University-Science A(Applied Physics & Engineering)2007，8，9： | 3 |
| 17 | Combined Liver Transplantation and Gastric Sleeve Resection for Patients With Medically Complicated Obesity and End‐Stage Liver Disease显示文摘 | J. K. Heimbach K. D. S. Watt J. J. Poterucha N. Francisco Ziller S. D. Cecco M. R. Charlton J. E. Hay R. H. Wiesner W. Sanchez C. B. Rosen J. M. Swain | 2012 | American Journal of Transplantation2012，，2： | 3 |
| 18 | Hemorrhage following colonoscopic polypectomy显示文摘 | Les Rosen M.D. David S. Bub B.S. James F. Reed Ph.D. Susan A. Nastasee B.S | 1993 | Diseases of the Colon & Rectum1993，，12： | 2 |
| 19 | 三元层状材料结构调控及性能研究进展显示文摘MAX/MAB相是一类非范德华三元层状材料,具有丰富的元素组成和晶体结构,兼具陶瓷和金属的物理性质,在高温、强腐蚀、辐照等极端环境中极具应用潜力。近年来,由MAX/MAB相衍生的二维(2D)材料(MXene和MBene)在材料物理与材料化学领域引起了广泛兴趣,已经成为继石墨烯和过渡金属硫族化合物之后最受关注的二维范德华材料。MAX/MAB相材料结构调控不仅对这类非范德华层状材料本征性能产生重要影响,而且对其衍生的二维范德华材料结构功能特性研究也具有重要价值。本文归纳和总结了MAX/MAB相层状材料在结构调控、理论计算和应用基础研究等方向的最新科研进展,并展望了该类层状材料未来发展方向。 | 丁浩明 李勉 李友兵 陈科 肖昱琨 周洁 陶泉争 Johanna ROSEN 尹航 柏跃磊 张毕堃 孙志梅 王俊杰 张一鸣 黄振莺 张培根 孙正明 韩美康 赵双 王晨旭 黄庆 | 2023 | 无机材料学报2023，38，8： | 2 |
| 20 | How robotics is changing and will change the field of colorectal surgery显示文摘During the last decade there has been a significant upward trend in colon and rectal minimally invasive surgery which can be attributed largely to the acceptance of robotic surgery platforms such as the da Vinci?robotic system.The fourth generation da Vinci?system,introduced in 2014,includes integrated table motion,intelligent laser targeted docking and more sophisticated instrumentation and imaging.These developments have enabled more surgeons to efficiently and safely perform multi-quadrant operations.Firefly?technology allows assessment of colon perfusion and identification of ureters,and has shown potential in detecting occult recurrence or metastasis using molecular-labelled tumor markers.Wristed instrumentation has increased the technical ease of intracorporeal anastomosis(ICA)for many surgeons,leading to more common use of ICA during right colectomy.Advanced imaging has shown potential to decrease the incidence of presacral nerve injury and improve urogenital outcomes after pelvic surgery,as has been the case in robotic urologic procedures.Finally,the robotic platform lends itself to surgical simulation for surgical trainees,as a pre-operative tool for mock operations and as an ongoing assessment tool for established colorectal surgeons.Given these advantages,surgeons should anticipate continued and increased utilization of this beneficial technology. | Crystal Koerner Seth Alan Rosen | 2019 | World Journal of Gastrointestinal Surgery2019，11，10： | 2 |
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