|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Alterations in metastatic properties of hepatocellular carcinoma cell following H-ras oncogene transfection显示文摘AIM To demonstrate the relationship betweenH-ras oncogene and hepatocellular carcinoma(HCC) metastasis.METHODS Activated H-ras oncogene wastransfected into SMMC 7721, a cell line derivedfrom human HCC, by calcium phosphatetransfection method. Some metastasis-relatedparameters were detected in vitro, includingadhesion assay, migration assay, expression ofcollagenase ⅣV (c ⅣV ase) and epidermal growthfactor receptor (EGFR).RESULTS The abilities of H-ras-transfected cellclones in adhesion to laminin (LN) or fibronectin(FN), migration, c Ⅳ ase secretion increasedmarkedly, and the expression of EGFR elevatedmoderately. More importantly, these alterationswere consistent positively with the expressionof p21, the protein product of H-ras oncogene.CONCLUSION H-ras oncogene could inducethe metastatic phenotype of HCC cell in vitro toraise its metastatic potential. | Qing Wang~1 Zhi Ying Lin~2 Xiao Li Feng~3 ~1Department of Microbiology,Medical Center of Fudan University.the former Shanghai Medical University,Shanghai 200032,China ~2Liver Cancer Institute,Zhongshan Hospital,Shanghai 200032,China ~3Shanghai Institute of Biochemistry,Academy Sinica,Shanghai 200031,ChinaQing Wang earned master degree from Shanghai Medical University in 1996,now a senior lecturer of microbiology,specialized in the role of oncogcncs on tumor metastasis,having 8 papers published. | 2001 | World Journal of Gastroenterology2001，7，3： | 48 |
| 2 | Response characteristics of an ascending auditory neuron AN3 and its projections in the brain of the bushcricket Gampsocleis grationsa显示文摘The phonotaxis of bushcrickets demonstrates that they have goodcapability of recognizing conspecific songs and locating the sound source,which bases on complicated auditory mechanisms of the central nervoussystem(CNS).This article describes the response characteristics of AN3,an auditory ascending neuron in the prothoracic ganglion,and its projec-tions within the brain.The AN3,with a quasi-tonic discharge pattern,has high sensitivity,directionality and ability to encode sound intensity.Therefore,it plays an important role in auditory information processingof CNS.Its projections in the brain are mainly concentrated in the lateralzone of the deutencephalon,where synaptically connecting local auditoryinterneurons in the brain. | GAO Panpan and SHEN Jun -Xian(Institute of Biophysics, Academia Sinica, Beijing 100080)The phonotaxis of bushcrickets demonstrates that they have good capability of recognizing conspecific songs and locating the sound source, which bases on complicated auditory mechanisms of the central nervous system (CNS). This article describes the response characteristics of AN3, an auditory ascending neuron in the prothoracic ganglion, and its projections within the brain. The AN3 , with a quasi-tonic discharge pattern, has high sensitivity, directionality and ability to encode sound intensity. Therefore, it plays an important role in auditory information processing of CNS. Its projections in the brain are mainly concentrated in the lateral zone of the deutencephalon, where synaptically connecting local auditory interneurons in the brain. | 1992 | Chinese Journal of Acoustics1992，11，1： | 3 |
| 3 | 在全球经济环境转变中土地利用决策的分化:印度班加罗尔的实例显示文摘本文探讨了在全球经济环境转变的影响下,印度城市班加罗尔在土地利用规划决策过程中所发生的变化,地方决策过程在重构中产生了分化因而导致冲突。本文重点分析了在这种变化过程中规划过程组织结构的转变,规划决策的合理性,权力结构的变化及其在地方层面引起的冲突。 | Rolee Aranya 杜潇芳 | 2003 | 国外城市规划2003，18，2： | 3 |
| 4 | Alpha4 beta2 neuronal nicotinic acet-ylcholine receptors in the central nervous system are inhibited by isoflurane and propofol, but alpha7-type nicotinic acetylcholine receptors are unaffected 显示文摘 | Flood P Ramirez-Latorre J Role L | 1997 | Anesthesiology1997，86，4： | 1 |
| 5 | Developmental regulation of nicotinic acetylcholine receptors显示文摘 | Role LW | 1987 | Ann Rev Neurosci1987，10，40： | 1 |
| 6 | Alpha 4 beta 2 neuronal nicotinic acetylcholine receptors in the central nervous system are inhibited by isoflurane and propofol,but alpha 7-type nicotinic acetylcholine receptors are unaffected显示文摘 | Flood P Ramirez-Latorre J Role L | 1997 | Anesthesiology1997，86，4： | 1 |
| 7 | cell makeover rather than cell death显示文摘 | Cecconi F Levine B The role of autophagy in mammalian develop-ment | 2008 | Dev Cell2008，15，： | 1 |
| 8 | White PF显示文摘 | Propofol:Its role in changing the practice of anesthesia | 2008 | Anesthesiology2008，109，6： | 1 |
| 9 | Back signaling by the Nrg-1 intracelular domain显示文摘 | Bao J Wolpowitz D Role LW Talmage DA | | 0，，： | 1 |
| 10 | Radial tunnel syndrome: resistant tennis elbow as nerve entrapment显示文摘 | Roles NC Maudsley RH | 1972 | J Bone Joint Surg Br1972，54，： | 1 |
| 11 | Endoscopy显示文摘 | Gay G Delvaux M Rey J E The role of video capsule endoscopy in the diagnosis of digestive diseases: a review of current possibilities | 2004 | Endoscopy2004，36，4： | 1 |
| 12 | Robust, hydrocarbon degradation and dynamics of bacterial communities during nutrient-enhanced oil spill bioremediation显示文摘 | WILFRED F ROLING M MICHAEL G | 2002 | Applied and Environmental Microbiology2002，68，11： | 1 |
| 13 | Wound metastases following laparoscopic and open surgery for abdominal cancer ina rat model显示文摘 | Mathew G Watson DI Role AM | 1996 | Br J Surg1996，83，： | 1 |
| 14 | A Neurophysiological Study显示文摘 | Smith AR Hosker GL Warrell DW〉The Role of Partial Denervation of the Pelvic Floor in the Aetiology of Genitourinary Prolapse and Stress Incontinence of Urine | 1989 | Br J Obstet and Gynaecol1989，96，： | 1 |
| 15 | Alpha 4 beta 2 neuronal nicotinic acetylcholine receptors in the central nervous system are inhibited by isoflurane and propofol, but alpha 7 - type nicotinic acetylcheline receptors are unaffected 显示文摘 | Flood P Ramirez - Latorre J Role L | 1997 | Anesthesiology1997，86，4： | 1 |
| 16 | Lancet显示文摘 | Adam IJ Mohamdee MO Martin IG Role of circumferential margin involvement in the local recurrence of rectal cancer | 1994 | 334:701~7071994，334，： | 1 |
| 17 | Innovative behavior in the of performance and image out- come expectations显示文摘 | Yuan F Woodman R workplace: The role W | 2010 | Academy of Management Jour- nal2010，53，2： | 1 |
| 18 | Strain rate dependence of the spall strength of steels显示文摘 | Buchar J Role S Hrebieek | 1997 | Journal de Physique-41997，7，3： | 1 |
| 19 | of infantile laryngotracheal haemangioma 显示文摘 | Denoyelle F Leboulanger N Enjolras O Role of propranolol in the therapeutic strategy | 2009 | Int J Pediatr Otorhinolaryngo12009，73，8： | 1 |
| 20 | Benign and malignant musculoskeletal lesion:Dynamic contrast-enhanced MR imaging-parametric first-pass images depict tissue vascularization and perfusion显示文摘 | Verstraete KL De Deene Y Roles H | 1994 | Radiology1994，192，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员