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| 1 | Situation Awareness of Active Distribution Network:Roadmap,Technologies,and Bottlenecks显示文摘With the rapid development of local generation and demand response,the active distribution network(ADN),which aggregates and manages miscellaneous distributed resources,has moved from theory to practice.Secure and optimal operations now require an advanced situation awareness(SA)system so that operators are aware of operation states and potential risks.Current solutions in distribution supervisory control and data acquisition(DSCADA)as well as the distribution automation system(DAS)generally are not able to meet the technology requirements of SA.In this paper,the authors’participation in the project of developing an SA system as the basic component of a practical active distribution management system(ADMS)deployed in Beijing,China,is presented.This paper reviews the ADN’s development roadmap by illustrating the changes that are made in elements,topology,structure,and control scheme.Taking into consideration these hardware changes,a systematic framework is proposed for the main components and the functional hierarchy of an SA system for the ADN.The SA system’s implementation bottlenecks are also presented,including,but not limited to issues in big data platform,distribution forecasting,and security evaluation.Potential technology solutions are also provided. | Jin Lin Can Wan Yonghua Song Renle Huang Xiaoshuang Chen Wanfang Guo Yi Zong You Shi | 2016 | CSEE Journal of Power and Energy Systems2016，2，3： | 13 |
| 2 | Ouabain at pathological concentrations might induce damage in human vascular endothelial cells显示文摘瞄准:为了在人的脐的静脉 endothelial (HUVEC ) 上检验哇巴因的时间依赖者和剂量依赖者效果,在大动脉的内皮细胞层和不同表示的在活体内,和变化 Kv4.2 铺平在试管内。方法:HUVEC 和细胞死亡的增长被 3-(4,5-dimethylthiazol-2-yl ) 决定 -2,5-diphenyl-2H-tetrazolium 溴化物(MTT ) 试金,加入[3H ] TdR,染色的尝试平底锅蓝色,和 lactate 脱氢酶(LDH ) 版本。到哇巴因的 endothelial 的反应与一个互补 DNA 微数组被探索,候选人基因被发现。Ouabain 敏感的高血压的老鼠被哇巴因的长期的管理建立。在大动脉的内皮细胞层的变化被电子显微镜学观察,并且表示在不同动物 Kv4.2 铺平被使用即时量的反向的抄写聚合酶链反应(RT-PCR ) 学习。结果:哇巴因在生理的集中(0.3-0.9 nmol/L ) 刺激了 HUVEC 的增长。在病理学的集中(0.9-1.8 nmol/L ) 的哇巴因禁止了增长并且导致了细胞死亡。mRNA 侧面分析显示 340 基因是在哇巴因处理以后表示的差别:145 起来调整,哪个 6 起来显著地调整了,包括 KCND2 (编码钾电压门隧道 shal 相关的亚科成员 2 ) 。起来调整基因主要与房间新陈代谢和抄写有关。在 ouabain 敏感的高血压的老鼠,大动脉的内皮细胞层被损坏并且 Kv4.2 (由 KCND2 编码了) 是过去表示的。结论:在 HUVEC 的哇巴因的生理的角色可能包含生长和新陈代谢的控制。在病理学的集中的哇巴因可能由 KCND2 基因的表示的修正影响脉管的内皮细胞层的结构和功能,并且参与在高血压的脉管的改变。 | Yan-ping RENl Ruo-wen HUANG Zhuo-ren LU | 2006 | Acta Pharmacologica Sinica2006，27，2： | 8 |
| 3 | TGIF2 promotes the progression of lung adenocarcinoma by bridging EGFR/RAS/ERK signaling to cancer cell stemness显示文摘TGF-β-induced factor homeobox 2(TGIF2)is a transcription regulator that plays essential roles in the regulation of development and cell fate decisions.Aberrant expression of TGIF family proteins has been observed in several cancers,including ovarian,esophageal,and colorectal cancers.Here,we report that TGIF2 mediates the EGFR–RAS–ERK signaling pathway to enhance the stemness of lung adenocarcinoma(LUAD)cells and,therefore,promote the progression and metastasis of LUAD.We found that high TGIF2 expression was closely correlated with tumor growth,lymph node metastasis,and survival of patients with LUAD.Mice bearing TGIF2-silenced H1299 xenografts developed smaller tumors and fewer lung metastases.Importantly,silencing TGIF2 decreased the cancer stem cell(CSC)-like properties in A549 and H1299 cells.Furthermore,we identified that TGIF2 binding to the OCT4 promoter promotes its expression.In both LUAD cells and in vivo LUAD mouse models,we revealed that EGFR–RAS–ERK signaling phosphorylated TGIF2 and increased its stability,which was important for TGIF2-promoted LUAD stemness since phosphorylation-deficient TGIF2 mutants lost these functions.Thus,our study revealed that an important factor,TGIF2,bridges EGFR signaling to the CSC characteristics of LUAD cells,which can be utilized as an effective target for LUAD therapy. | Renle Du Wenzhi Shen Yi Liu Wenjuan Gao Wei Zhou Jun Li Shuangtao Zhao Chong Chen Yanan Chen Yanhua Liu Peiqing Sun Rong Xiang Yi Shi Yunping Luo | 2019 | Signal Transduction and Targeted Therapy2019，4，1： | 7 |
| 4 | WangFX(王伏雄),FmbryologicalstudyofPaphiopedilumgodefroyaeStein[J]显示文摘 | RenL(任玲) | | 植物学报0，，： | 1 |
| 5 | EmbryologicalstudiesofPaphiopedilumgodefroyaeStein[J]显示文摘 | RENL(任玲) WANGFX(王伏雄) | | 植物学报0，，： | 1 |
| 6 | Experimental investigation on lateral performance of pre-stressed tube bolted connection with high initial stiffness 显示文摘 | HE Minjuan ZHAO Yi MA Renle | 2016 | Advaces in Structural Engineering2016，19，5： | 1 |
| 7 | RelationshipbetweenmetalionwithAlzheimer’sdisease显示文摘 | RenL(任琳) etal | | 生命的化学0，，： | 1 |
| 8 | Preven- tion and treatment of bone cement related complications in patients receiving percutaneous kyphoplasty显示文摘 | Kaining Zhang Yingchun Shen Yanjun Renl | 2015 | Int J Clin Exp Med2015，8，2： | 1 |
| 9 | Topical tacrolimus(FK506) and mometasone furoate in treatment of dyshidrotic palmar eczema: A randomized, observer-blinded trial显示文摘 | Renling R Mohrenschlager M | 2002 | J Am Acad Dermatol2002，46，1： | 1 |
| 10 | Promotional effect of colloidal alumina on the activity of the In/HZSM-5 catalyst for the selective reduction of NO with methane 显示文摘 | RenL Zhang T Tang J | 2003 | Applied Catalysis B:Environmental2003，41，： | 1 |
| 11 | Mast cell tryptase may modulate endothelial cell phenotype in healing myocardial infarcts 显示文摘 | Somasundaraml P Renl GF Nagarl H | 2005 | Pathol2005，205，1： | 1 |
| 12 | Resistance to chemothera- py via STAT3 dependent overexpression of Bcl-2 in metastatic breast cancer cell 显示文摘 | Renl PJ Sierra A Juan A | 2002 | Oneogene2002，21，50： | 1 |
| 13 | Acetoacetate promotes muscle cell proliferation via the miR-133b/SRF axis through the Mek-Erk-MEF2 pathway显示文摘Acetoacetate(AA)is an important ketone body that is used as an oxidative fuel to supply energy for the cellular activities of various tissues,including the brain and skeletal muscle.We recently revealed a new signaling role for AA by showing that it promotes muscle cell proliferation in vitro,enhances muscle regeneration in vivo,and ameliorates the dystrophic muscle phenotype of Mdx mice.In this study,we provide new molecular insight into this function of AA.We show that AA promotes C2C12 cell proliferation by transcriptionally upregulating the expression of muscle-specific miR-133b,which in turn stimulates muscle cell proliferation by targeting serum response factor.Furthermore,we show that the AA-induced upregulation of miR-133b is transcriptionally mediated by MEF2 via the Mek-Erk1/2 signaling pathway.Mechanistically,our findings provide further convincing evidence that AA acts as signaling metabolite to actively regulate various cellular activities in mammalian cells. | Ran Zhong Renling Miaot Jiao Meng Rimao Wu Yong Zhang Dahai Zhu | 2021 | Acta Biochimica et Biophysica Sinica2021，53，8： | 1 |
| 14 | PeanutvarietyandpedigreeanalysisinHenanProvince(河南花生品种及系谱分析)[J]显示文摘 | ITANGFS(汤丰收) ZHANGXY(张新友) RENL(任丽) etal | | 中国油料作物学报0，，： | 1 |
| 15 | Dynamic reserve allocation for system contingency by DFIG wind farms显示文摘 | Renl Chien C Hung C M | | 0，，02： | 1 |
| 16 | EmbryologicalstudiesofPaphiopedilumgodefroyaeStein显示文摘 | RENL(任玲) WANGFx(王伏雄) | 1987 | 植物学报1987，29，1： | 1 |
| 17 | Viraland myco plasma p- neumoniaecommunity acquired pneumonia and novel clinical outcome evaluation in ambulatory adult PatientsinChina 显示文摘 | CAOB RENL L ZHAOF | 2010 | Eur J Clin MierobiolInfeet Dis2010，29，11： | 1 |
| 18 | General anesthesia combined with epidural anesthesia ameliorates the effect of fast-track surgery by mitigating immunosuppression and facilitating intestinal functional recovery in colon cancer patients显示文摘 | Chen W K RenL WeiY | 2015 | International Journal of Colorectal Disease2015，30，4： | 1 |
| 19 | The buzz on buzz显示文摘 | DYE RENl(E)E | | 0，，： | 1 |
| 20 | Neuroprotectiveeffectofarctige-ninviaupregulationofP-CREBinmouseprimaryneuronsandhu-manSH-SY5Yneuroblastomacells显示文摘 | ZhangN WenQ RenL etal | 2013 | IntJMolSci2013，14，18： | 1 |
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