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| 1 | Photodegradation of 17α-ethynylestradiol in dissolved humic substances solution:Kinetics,mechanism and estrogenicity variation显示文摘17α-Ethynylestradiol(EE2) in natural waters may cause adverse effects on organisms due to its high estrogenic potency. Laboratory studies were performed to study the effects of a local humic acid(LHA), fulvic acid(LFA) and Aldrich humic acid(AHA) on the photochemical behavior and estrogenic potency of EE2. Here photolytic experiments demonstrated that pure aqueous EE2 could undergo direct and self-sensitized photodegradation at a global rate of 0.0068 hr^(-1).Photodegradation rate of EE2 in 5.0 mg/L dissolved humic substances(DHS) was determined to be 0.0274, 0.0296 and 0.0254 hr^(-1) for LHA, LFA and AHA, respectively. Reactive oxygen species(ROS) and triplet dissolved humic substances(~3DHS*) scavenging experiments indicated that the promotion effect of DHS on EE2 photodegradation was mainly aroused by the reactions of HOU(35%–50%),~1O_2(<10%) andDHS*(22%–34%). However, the photodegradation of EE2 could also be inhibited when DHS exceeded the threshold of 10 mg/L. Three hydroxylation products of EE2 were identified using GC–MS and their formation pathways were also proposed. In vitro estrogenicity tests showed that EE2 was transformed into chemicals without estrogenic potency. These findings could extend our knowledge on the photochemical behaviors of steroid estrogens in sunlit natural waters. | Dong Ren Bin Huang Dan Xiong Huan He Xiangqi Meng Xuejun Pan | 2017 | Journal of Environmental Sciences2017，29，4： | 9 |
| 2 | Pioneering function of Isl1 in the epigenetic control of cardiomyocyte cell fate显示文摘Generation of widely differing and specialized cell types from a single totipotent zygote involves large-scale transcriptional changes and chromatin reorganization. Pioneer transcription factors play key roles in programming the epigenome and facilitating recruitment of additional regulatory factors during successive cell lineage specification and differentiation steps. Here we show that Isl1 acts as a pioneer factor driving cardiomyocyte lineage commitment by shaping the chromatin landscape of cardiac progenitor cells. Using an Isl1 hypomorphic mouse line which shows congenital heart defects, genome-wide profiling of Isl1 binding together with RNA- and ATAC-sequencing of cardiac progenitor cells and their derivatives, we uncover a regulatory network downstream of Isl1 that orchestrates cardiogenesis. Mechanistically, we show that Isl1 binds to compacted chromatin and works in concert with the Brg1-Baf60c-based SWI/SNF complex to promote permissive cardiac lineage-specific alterations in the chromatin landscape not only of genes with critical functions in cardiac progenitor cells, but also of cardiomyocyte structural genes that are highly expressed when Isl1 itself is no longer present. Thus, the Isl1/Brg1-Baf60c complex plays a crucial role in orchestrating proper cardiogenesis and in establishing epigenetic memory of cardiomyocyte fate commitment. | Rui Gao Xingqun Liang Sirisha Cheedipudi Julio Cordero Xue Jiang Qingquan Zhang Luca Caputo Stefan Günther Carsten Kuenne Yonggang Ren Shoumo Bhattacharya Xuejun Yuan Guillermo Barreto Yihan Chen Thomas Braun Sylvia M. Evans Yunfu Sun Gergana Dobreva | 2019 | Cell Research2019，29，6： | 5 |
| 3 | Analysis and experimentation of key technologies in service-oriented optical internet显示文摘To satisfy diverse bandwidth-intensive applications envisioned in the internet of the future, research on a distributed optical internet, enabling efficient utilization of geographically distributed resources, has become attractive. The deployment of such a network, however, has its own technical challenges, including network architecture, resource management, and high-speed transmission. To address these issues, a service-oriented-architecture-based distributed optical internet architecture is proposed. Thereafter, key technologies of an optical internet, such as optical multicasting, distributed resource control, and high-speed transmission, are analyzed and investigated. The proposed schemes are verified through experimentation and simulation. | JI YueFeng REN DanPing LI Hui LIU XueJun WANG ZhengZhong | 2011 | Science China(Information Sciences)2011，54，2： | 3 |
| 4 | AGRICULTURAL GREEN DEVELOPMENT TO ACHIEVE FOOD SECURITY AND CARBON REDUCTION IN THE CONTEXT OF CHINA'S DUAL CARBON GOALS显示文摘The agricultural sector,a major source of greenhouse gas emissions,and emissions from agriculture must be reduced substantially to achieve carbon(C)neutrality.Based on a literature analysis and other research results,this study investigated the effects and prospects of C reduction in agricultural systems under different scenarios(i.e.,methods and approaches)in the context of China's dual C goals,as those working in the agricultural sector have yet to reach a consensus on how to move forward.Different views,standards,and countermeasures were analyzed to provide a reference for agricultural action supporting China's C neutrality goal. | Yulong YIN Kai HE Zhong CHEN Yangyang LI Fengling REN Zihan WANG Yingcheng WANG Haiqing GONG Qichao ZHU Jianbo SHEN Xuejun LIU Zhenling CUI | 2023 | Frontiers of Agricultural Science and Engineering2023，10，2： | 2 |
| 5 | RanBPM is an acetylcholinesterase-interacting protein that translocates into the nucleus during apoptosis显示文摘Acetylcholinesterase (疼痛) 表示可以在各种各样的房间类型在 apoptosis 期间被导致。这里,我们使用了疼痛的 C 终端屏蔽人的胎儿的大脑图书馆并且发现它在组织微导管的中心(RanBPM ) 与跑绑定蛋白质交往了。这个相互作用被 coimmunoprecipitation 分析进一步证实。在 HEK293T 房间, RanBPM 和疼痛不同类地在 cisplatin 未经治疗的细胞质的摘录并且在对待 cisplatin 的细胞质或原子的摘录被表示。我们用词法方法执行的以前的研究在 apoptosis 期间从细胞质显示出那疼痛 translocates 到原子核。一起拿,这些结果建议 RanBPM 是在 apoptosis 期间是从进原子核的细胞质的 translocated 的交往疼痛的蛋白质,类似于在疼痛的情况下观察的 translocation。 | Xiaowen Gong Weiyuan Ye Haibo Zhou Xiaohui Ren Zhigang Li Weiyin Zhou Jun Wu Yicheng Gong Qi Ouyang Xiaolin Zhao Xuejun Zhang | 2009 | Acta Biochimica et Biophysica Sinica2009，41，11： | 2 |
| 6 | Stress - Strain Behaviors Simulation of High Chromium Steel at Elevated Temperatures显示文摘 | Ligang Liu Qiang Li Bo Liao Yukui Gao Yuhui Wang Xuejun Ren and Qingxiang Yang | 2010 | Journal of Ma- terials Engineering and Performance2010，，19： | 1 |
| 7 | Phase diagram calculation of high chromium cast irons and influence of its chemical composition显示文摘 | Da Li Ligang Liu Yunkun Zhang Chunlei Ye Xuejun Ren Yulin Yang Qingxiang Yang | 2008 | Materials and Design2008，，2： | 1 |
| 8 | Effect of Rare Earth Elements on Thermal Fatigue of High Ni-Cr Alloy Cast Iron显示文摘 | Yang Qingxiang Wang Airong Ren Xuejun et 81 | 1996 | J Rare Earths1996，14，4： | 1 |
| 9 | Effects of aging treatment on martensitic transformation of Fe–Ni–Co–Al–Ta–B alloys显示文摘 | Yonghong Geng Mingjiang Jin Wenjing Ren Weimin Zhang Xuejun Jin | 2012 | Journal of Alloys and Compounds2012，，： | 1 |
| 10 | Effect of Carburization on Residual Stress Field of 20CrMnTi Specimen and Its Numerical Simulation 显示文摘 | Yang Qingxiang Ren Xuejun Gao Yukui | 2005 | Materials Science and Engineering2005，392，12： | 1 |
| 11 | Effect of rare earth elements on thermal fatigue of high Ni-Cr alloy cast iron显示文摘 | Yang Qingxiang Wang Airong Ren Xuejun | 1996 | J Rare Earths1996，14，4： | 1 |
| 12 | Brake performance snalysis of ABS for eddy current and electrohydraulic hybrid brake system显示文摘 | He Ren Liu Xuejun Liu Cunxiang | 2013 | Mathematical Problems in Engineering2013，，2013： | 1 |
| 13 | Study on crustal deformation of the Ms6.6 Damxungearthquake in 2008 by InSAR measurements显示文摘从 ESA 的三幅 Envisat 图象被用来导出 pre -- 并且 co 地震的变丑 interfereo 克由 Damxung Ms6 引起了。10 月 6,2008 日的 6 地震,由使用 InSAR。结果不显示出重要外壳的运动在地震前的超过 4 个月,而是在 20 km 瑡ㄠ琩敨搠獩潬慣楴湯挠湯楳瑳 ? 景搠灩猠楬? 湡 ? 楲桧 ? 慬整慲? 瑳楲敫猠楬? 学琩敨挠 ? 敳獩業? 牧癡瑩 ? 的一个震央的区域的大约 0.3 m 的最大的 co 地震的排水量档湡敧猠潨獷愠映畯 ? 畱摡慲瑮瀠瑡整湲 ? 桷捩 ? 獩朠敲瑡祬挠湯牴汯敬 ? 祢琠敨搠獩牴扩瑵潩 ? 景琠敨瘠牥楴慣? 楤灳慬散敭瑮 ? 獥数楣污祬椠 ? 桴 ? 敮牡昭汩摥 ? 琩敨朠慲楶祴挠慨杮? 獩朠湥牥污祬氠獥 ? 桴湡ㄠ鬰鵅钡吗?? | Xuejun Qiao Shanjun Ren Zhaosheng Nie Yu Zhou Qiang Shen Shaomin Yang | 2010 | Geodesy and Geodynamics2010，1，1： | 1 |
| 14 | Preparationand properties of the organic-inorganic compositecoating on aluminum alloy显示文摘 | Li Guojun Cui Xuejun Ren Ruiming | 2011 | Materials Science Fo-rum Vols2011，，： | 1 |
| 15 | Brake performanceanalysis of abs for eddy current and electrohydraulic hy-brid brake system 显示文摘 | He Ren Liu Xuejun Liu Cunxiang | | Mathematical Problems in0，，： | 1 |
| 16 | A pilot study in different unstable designs on the biomechanical effect of gait characteristics显示文摘 | Gu Yaodong Li Jianshe Ren Xuejun | 2012 | J Mech Med Biol2012，12，5： | 1 |
| 17 | Dissolved organic matter accelerates microbial degradation of 17 alpha-ethinylestradiol in the presence of iron mineral显示文摘Dissolved organic matter(DOM)and iron minerals widely existing in the natural aquatic environment can mediate the migration and transformation of organic pollutants.However,the mechanism of interaction between DOM and iron minerals in the microbial degradation of pollutants deserves further investigation.In this study,the mechanism of 17 alphaethinylestradiol(EE2)biodegradation mediated by humic acid(HA)and three kinds of iron minerals(goethite,magnetite,and pyrite)was investigated.The results found that HA and iron minerals significantly accelerated the biodegradation process of EE2,and the highest degradation efficiency of EE2(48%)was observed in the HA-mediated microbial system with pyrite under aerobic conditions.Furthermore,it had been demonstrated that hydroxyl radicals(HO·)was the main active substance responsible for the microbial degradation of EE2.HO·is primarily generated through the reaction between hydrogen peroxide secreted by microorganisms and Fe(II),with aerobic conditions being more conducive.The presence of iron minerals and HA could change the microbial communities in the EE2 biodegradation system.These findings provide new information for exploring the migration and transformation of pollutants by microorganisms in iron-rich environments. | Huan He Min Shi Xiaoxia Yang Juhong Zhan Yanting Lin Ziwei Guo Zhicheng Liao Chaochao Lai Xiaomin Ren Bin Huang Xuejun Pan | 2024 | Journal of Environmental Sciences2024，，5： | 0 |
| 18 | Post-transcriptional regulation of grain weight and shape by the RBP-A-J-K complex in rice显示文摘RNA-binding proteins(RBPs)are components of the post-transcriptional regulatory system,but their regulatory effects on complex traits remain unknown.Using an integrated strategy involving map-based cloning,functional characterizations,and transcriptomic and population genomic analyses,we revealed that RBP-K(LOC_Os08g23120),RBP-A(LOC_Os11g41890),and RBP-J(LOC_Os10g33230)encode proteins that form an RBP-A-J-K complex that negatively regulates rice yield-related traits.Examinations of the RBP-A-J-K complex indicated RBP-K functions as a relatively non-specific RBP chaperone that enables RBP-A and RBP-J to function normally.Additionally,RBP-J most likely affects GA pathways,resulting in considerable increases in grain and panicle lengths,but decreases in grain width and thickness.In contrast,RBP-A negatively regulates the expression of genes most likely involved in auxin-regulated pathways controlling cell wall elongation and carbohydrate transport,with substantial effects on the rice grain filling process as well as grain length and weight.Evolutionarily,RBP-K is relatively ancient and highly conserved,whereas RBP-J and RBP-A are more diverse.Thus,the RBP-A-J-K complex may represent a typical functional model for many RBPs and protein complexes that function at transcriptional and post-transcriptional levels in plants and animals for increased functional consistency,efficiency,and versatility,as well as increased evolutionary potential.Our results clearly demonstrate the importance of RBP-mediated post-transcriptional regulation for the diversity of complex traits.Furthermore,rice grain yield and quality may be enhanced by introducing various complete or partial loss-of-function mutations to specific RBP genes using clustered regularly interspaced palindromic repeats(CRISPR)/CRISPR-associated protein 9 technology and by exploiting desirable natural tri-genic allelic combinations at the loci encoding the components of the RBP-A-J-K complex through marker-assisted selection. | Ding Ren Hui Liu Xuejun Sun Fan Zhang Ling Jiang Ying Wang Ning Jiang Peiwen Yan Jinhao Cui Jinshui Yang Zhikang Li Pingli Lu Xiaojin Luo | 2024 | Journal of Integrative Plant Biology2024，66，1： | 0 |
| 19 | Unstable Allotetraploid Tobacco Genome due to Frequent Homeologous Recombination, -. Segmental Deletion, and Chromosome Loss显示文摘 | Shumin Chen Feihong Ren Lei Zhang Yong Liu Xuejun Chen Yuanmei Li Liang Zhang Bin Zhu Pan.Zeng Zaiyun Li Robert M. Larkin Hanhui Kuang | 2018 | Molecular Plant2018，11，7： | 0 |
| 20 | Carbon matrix/SiNWs heterogeneous block as improved reversible anodes material for lithium ion batteries显示文摘A novel carbon matrix/silicon nanowires(SiNWs) heterogeneous block was successfully produced by dispersing SiNWs into templated carbon matrix via a modified evaporation induced self-assembly method. The heterogeneous block was determined by X-ray diffraction, Raman spectra and scanning electron microscopy. As an anode material for lithium batteries, the block was investigated by cyclic voltammograms(CV), charge/discharge tests, galvanostatic cycling performance and A. C. impedance spectroscopy. We show that the SiNWs disperse into the framework, and are nicely wrapped by the carbon matrix. The heterogeneous block exhibits superior electrochemical reversibility with a high specific capacity of 529.3 mAh/g in comparison with bare SiNWs anode with merely about 52.6 mAh/g capacity retention. The block presents excellent cycle stability and capacity retention which can be attributed to the improvement of conductivity by the existence of carbon matrix and the enhancement of ability to relieve the large volume expansion of SiNWs during the lithium insertion/extraction cycle. The results indicate that the as-prepared carbon matrix/SiNWs heterogeneous block can be an attractive and potential anode material for lithium-ion battery applications. | Yao Wang Long Ren Yundan Liu Xuejun Liu Kai Huang Xiaolin Wei Jun Li Xiang Qi Jianxin Zhong | 2014 | Journal of Energy Chemistry2014，23，1： | 0 |
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