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| 1 | Update on pathogenesis and predictors of response of therapeutic strategies used in inflammatory bowel disease显示文摘The search for biomarkers that characterize specific aspects of inflammatory bowel disease(IBD), has received substantial interest in the past years and is moving forward rapidly with the help of modern technologies. Nevertheless, there is a direct demand to identify adequate biomarkers for predicting and evaluating therapeutic response to different therapies. In this subset, pharmacogenetics deserves more attention as part of the endeavor to provide personalized medicine. The ultimate goal in this area is the adjustment of medication for a patient's specific genetic background and thereby to improve drug efficacy and safety rates. The aim of the following review is to utilize the latest knowledge on immunopathogenesis of IBD and update the findings on the field of Immunology and Genetics, to evaluate the response to the different therapies. In the present article, more than 400 publications were reviewed but finally 287 included based on design, reproducibility(or expectancy to be reproducible and translationable into humans) or already measured in humans. A few testshave shown clinical applicability. Other, i.e., genetic associations for the different therapies in IBD have not yet shown consistent or robust results. In the close future it is anticipated that this, cellular and genetic material, as well as the determination of biomarkers will be implemented in an integrated molecular diagnostic and prognostic approach to manage IBD patients. | Emilio G Quetglas Zlatan Mujagic Simone Wigge Daniel Keszthelyi Sebastian Wachten Ad Masclee Walter Reinisch | 2015 | World Journal of Gastroenterology2015，21，44： | 3 |
| 2 | Imaging techniques for assessment of inflammatory bowel disease: Joint ECCO and ESGAR evidence-based consensus guidelines显示文摘 | J. Panes Y. Bouhnik W. Reinisch J. Stoker S.A. Taylor D.C. Baumgart S. Danese S. Halligan B. Marincek C. Matos L. Peyrin-Biroulet J. Rimola G. Rogler G. van Assche S. Ardizzone A. Ba-Ssalamah M.A. Bali D. Bellini L. Biancone F. Castiglione R. Ehehalt R. G | 2013 | Journal of Crohn’s and Colitis2013，，7： | 2 |
| 3 | Imaging techniques for assessment of inflammatory bowel disease: Joint ECCO and ESGAR evidence-based consensus guidelines显示文摘 | J. Panes Y. Bouhnik W. Reinisch J. Stoker S.A. Taylor D.C. Baumgart S. Danese S. Halligan B. Marincek C. Matos L. Peyrin-Biroulet J. Rimola G. Rogler G. van Assche S. Ardizzone A. Ba-Ssalamah M.A. Bali D. Bellini L. Biancone F. Castiglione R. Ehehalt R. G | 2013 | Journal of Crohn’s and Colitis2013，，7： | 1 |
| 4 | Determination of the Relative Molecular Weight of Poly by Viscosimetry of Solutions显示文摘 | Wandrey C Jaeger W Reinisch G | 1982 | Acta Polymerica1982，33，2： | 1 |
| 5 | New digisonde for research and monitoring applica-tions显示文摘 | REINISCH B W GALKIN I A KHMYROV G M etal | 2009 | Radio Science2009，44，1： | 1 |
| 6 | Determination of the Relative Molecular Weight of Poly(Dimethyldiallylammonium Chloride) by Viscosimetry of Solutions显示文摘 | Wandrey C Jaeger W Reinisch G | 1982 | Acta Polymerica1982，33，2： | 1 |
| 7 | Efficient MRI labeling of endothelial progenitor ceils: thiolated surface superparamagnetic design of stabilized iron nanoparticles显示文摘 | Shahnaz G Kremser C Reinisch A | 2013 | Eur J Biopharm2013，85，3： | 1 |
| 8 | The second European evidence-based Consensus on the diagnosis and management of Crohn' s disease:special situations显示文摘 | Van Assche G Dignass A Reinisch W | 2010 | J Crohns Colitis2010，4，1： | 1 |
| 9 | Determination of the Relative Molecular W - eight of Poly ( Dimethyldiallylammonium Chloride) by Viscosimetry of Solutions 显示文摘 | Wandrey C Jaeger W Reinisch G | 1982 | ActaPolymerica1982，33，2： | 1 |
| 10 | Intralesional corticosteroid therapy for infantile hemangiomas显示文摘 | Sloan G M Reinisch J F Nichter L S | 1989 | Plast Reconstr Surg1989，83，3： | 1 |
| 11 | The second Europe- an evidence-based Consensus on the diagnosis and management of Crohn's disease : Special situations 显示文摘 | Van Assche G Dignass A Reinisch W | 2010 | J Crohns Colitis2010，4，1： | 1 |
| 12 | Kinetics,mass transp-ort and thoughts about the mechanism of the formation of polyethylene terephthalate by metal ion catalysis显示文摘 | RAFLER G REINISCH G BONATZ E | 1974 | Acta Chem (Budapest)1974，81，： | 1 |
| 13 | The second European evidence-based Consensus on the diagnosis and management of Crohn's disease:Special situations显示文摘 | Van Assche G Diqnass A Reinisch W | 2010 | J Crohns Colitis2010，4，1： | 1 |
| 14 | New Digisonde for research and monitoring applications显示文摘 | Reinisch B W Galkin I A Khmyrov G M | | 0，，： | 1 |
| 15 | Determination of the relative molec-ular weight of poly(dimethyldiallylammonium chloride) by viscosimetry of solutions显示文摘 | Wandrey C Jaeger W Reinisch G | 1982 | Acta Polymerica1982，33，2： | 1 |
| 16 | The second European evidence-based Consensus on the diagnosis and management of Crohn's disease:Special situations显示文摘 | Van Assche G Dignass A Reinisch W | 2010 | J Crohns Colitis2010，4，1： | 1 |
| 17 | Recommendations for the treatment of ulcerative colitis with infliximab:a gastroenterolo-gy expert group consensus显示文摘 | Reinisch W Van Assche G Befrits R | | 0，，02： | 1 |
| 18 | Adalimumab in- duces and maintains clinical remission in patients with moderate-to-severe ulcerative colitis 显示文摘 | Sandborn WJ van Assche G Reinisch W | 2012 | Gastroenterology2012，142，2： | 1 |
| 19 | The second European evidence-based Consensus on the diagnosis and management of Crohn's disease : Special situations 显示文摘 | Van Assche G Dignass A Reinisch W | 2010 | J Crohns Colitis2010，4，1： | 1 |
| 20 | Adalimumab in-duces and maintains clinical remission in patients with moderate-to-severe ulcerative colitis显示文摘 | Sandborn WJ van Assche G Reinisch W | | 0，，02： | 1 |
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