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| 1 | Heat shock protein 90 inhibition by 17-DMAG lessens disease in the MRL/Ipr mouse model of systemic lupus erythematosus显示文摘热吃惊蛋白质 90 的提高的表示(HSP90 ) 在全身的豺狼座 erythematosus (SLE ) 的肾和浆液被发现了病人和 MRL/Mp-Fas lpr /Fas lpr (MRL/lpr ) 自体免疫的老鼠。如果 HSP90 的抑制将在 MRL/lpr 老鼠减少疾病,我们调查了。在在 vivo 的 vitro,有在 IL-6 的有免疫力刺激的显示出的减少的表示以前的 HSP90 禁止者 Geldanamycin 的 mesangial 房间的预告的处理, IL-12 和号码,我们发现当与 C57BL/6 相比鼠标和 MRL/lpr 鼠标与 HSP90 禁止者 17-DMAG 对待时, HSP90 表示在 MRL/lpr 肾被提高。与 17-DMAG 对待的 MRL/lpr 老鼠显示出减少的 proteinuria 并且减少了浆液 anti-dsDNA 抗体生产。Glomerulonephritis 和 glomerular IgG 和 C3 没被 17-DMAG 的管理显著地在 MRL/lpr 影响。17-DMAG 增加了 CD8 + T 房间,减少的双 negative T 房间,减少 CD4/CD8 比率和减少的小囊的 B 房间。这些研究建议 HSP90 可以在调整 T 房间区别和激活起一个作用并且 HSP90 抑制可以在豺狼座减少发炎。 | Samuel K Shimp III Cristen B Chafin Nicole L Regna Sarah E Hammond Molly A Read David L Caudell Marissa Nichole Rylander Christopher M Reilly | 2012 | Cellular & Molecular Immunology2012，9，3： | 3 |
| 2 | Creep and physical aging of PVC: dependence on stress and temperature显示文摘 | Read B E Dean G D Tomlins P E | 1994 | Journal of Non-CrystaUine Solids1994，，： | 1 |
| 3 | Physical properties of axenic maize root mucilage显示文摘 | Read D B Gregory P J Bell A E | 1999 | Plant and Soil1999，211，： | 1 |
| 4 | An ovary transcriptome for all maturational stages of the striped bass ( Morone saxatilis) , a highly advanced perciform fish 显示文摘 | Reading B J Chapman R W Schaff J E | 2012 | BMC Research Notes2012，5，： | 1 |
| 5 | An maturational stages of the striped bass ( Morone saxatilis) , a highly advanced perciform fish 显示文摘 | Reading B J Chapman R ovary transcriptome for all W Schaff J E | 2012 | BMC Research Notes2012，5，： | 1 |
| 6 | Physical properties of axenicmaize root mucilage显示文摘 | Read D B Gregory P J Bell A E | 1999 | Plant Soil1999，211，： | 1 |
| 7 | Prevalence and significance of coagulation abnormalities in community-acquired pneumonia显示文摘 | MILBRANDT E B READE M C LEE M | 2009 | Mol Med2009，15，1112： | 1 |
| 8 | Time-dependent Deformation of Potypropylene in Response to Different Stress Histories显示文摘 | READ B E TOMLINS P E | 1997 | Polymer1997，38，18： | 1 |
| 9 | Creep and Physical Ageing of Polypropylene: a Comparison of Models显示文摘 | READ B E TOMLINS P E | 1997 | Polymer1997，39，2： | 1 |
| 10 | Time-dependent deformation of polypropylene in response to different stress histories显示文摘 | Read B E Tomlins P E | 1997 | Polymer1997，38，18： | 1 |
| 11 | Therapeutic potential of mesenchymal stem cells for severe acute lung injury显示文摘 | MATTHAY M A THOMPSON B T READ E J | | 0，，04： | 1 |
| 12 | Creep and physical ageing of polypropylene:a comparison of models显示文摘 | Tomlins P E Read B E | 1998 | Polymer1998，39，2： | 1 |
| 13 | Effects of physical ageing on creep in polypropylene显示文摘 | Read B E Dean G D Tomlins P E | 1988 | Polymer1988，29，12： | 1 |
| 14 | Creep and physical ageing in PVC at high stresses显示文摘 | Dean G D Read B E Lesniarek-Hamid J L | 1992 | Plast Rubber Compos Proces Appl1992，17，4： | 1 |
| 15 | A model for nonlinear creep and physical aging in poly (vinyl chloride)显示文摘 | Dean G D Tomlins P E Read B E | 1995 | Polym Eng Sci1995，35，16： | 1 |
| 16 | GIS and biogeochemical models for examining the legacy of forest disturbance in the Adirondack Park, NY, USA 显示文摘 | McNeil B E Martell R E Read J M | 2006 | Ecological Modelling2006，195，34： | 1 |
| 17 | Prevalence and significance of coagulation abnormalities in community - acquired pneumonia 显示文摘 | Milbrandt E B Reade M C Lee M | 2009 | Mol Med2009，15，： | 1 |
| 18 | Time-dependent deformation of polypropylene in response to different stress histories 显示文摘 | READ B E TOMLINS P E | 1997 | Polymer1997，38，18： | 1 |
| 19 | Creep and physical ageing of polypropylene: a comparison of models 显示文摘 | READ B E TOMLINS P E | 1997 | Polymer1997，39，2： | 1 |
| 20 | No consistent effect of plant diversity on productivity显示文摘 | Huston M A Aarssen L W Austin M P Cade B S Fridley J D Garnier E Grime J P Hodgson J Lauenroth W K Thompson K Vandermeer J H Wardle D A Hector A Schmid B Beierkuhnlein C Caldeira M C Diemer M Dimitrakopoulos P G Finn J A Freitas H Giller P S Good J Harris R Hogberg P Huss-Danell K Joshi J Jumpponen A Korner C Leadley P W Loreau M Minns A Mulde C P H O'Donovan G Otway S J Pereira J S Prinz A Read D J Scherer-Lorenzen M Schulze E D Siamanrziouras A S D Spehn E Terry A C Troumbis A Y Woodward F I Yaehi S Lawton J H | 2000 | Science2000，289，： | 1 |
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