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| 1 | Relationship between Th17 immune response and cancer显示文摘Cancer is the second leading cause of death worldwide and epidemiological projections predict growing cancer mortality rates in the next decades.Cancer has a close relationship with the immune system and,although Th17 cells are known to play roles in the immune response against microorganisms and in autoimmunity,studies have emphasized their roles in cancer pathogenesis.The Th17 immune response profile is involved in several types of cancer including urogenital,respiratory,gastrointestinal,and skin cancers.This type of immune response exerts pro and antitumor functions through several mechanisms,depending on the context of each tumor,including the protumor angiogenesis and exhaustion of T cells and the antitumor recruitment of T cells and neutrophils to the tumor microenvironment.Among other factors,the paradoxical behavior of Th17 cells in this setting has been attributed to its plasticity potential,which makes possible their conversion into other types of T cells such as Th17/Treg and Th17/Th1 cells.Interleukin(IL)-17 stands out among Th17-related cytokines since it modulates pathways and interacts with other cell profiles in the tumor microenvironment,which allow Th17 cells to prevail in tumors.Moreover,the IL-17 is able to mediate pro and antitumor processes that influence the development and progression of various cancers,being associated with variable clinical outcomes.The understanding of the relationship between the Th17 immune response and cancer as well as the singularities of carcinogenic processes in each type of tumor is crucial for the identification of new therapeutic targets. | Hanna Santos Marques Breno Bittencourt de Brito Filipe Antônio França da Silva Maria Luísa Cordeiro Santos Júlio César Braga de Souza Thiago Macêdo Lopes Correia Luana Weber Lopes Nayara Silva de Macêdo Neres Rafael Santos Dantas Miranda Dórea Anna Carolina Saúde Dantas Lorena Lôbo Brito Morbeck Iasmin Souza Lima Amanda Alves de Almeida Maiara Raulina de Jesus Dias Fabrício Freire de Melo | 2021 | World Journal of Clinical Oncology2021，12，10： | 5 |
| 2 | NSAID use and dementia risk in the Cardiovascular Health Study*: Role of APOE and NSAID type显示文摘 | C A. Szekely J C.S. Breitner A L. Fitzpatrick T D. Rea B M. Psaty L H. Kuller P P. Zandi | 2008 | Neurology2008，，1： | 2 |
| 3 | 特发性肺间质纤维化患者疱疹病毒感染与血管重塑、肺高血压相关显示文摘肺高血压是特发性肺问质纤维化(idiopathic pulmonary fibrosis,IPF)的主要并发症,对患者预后有不良影响。目前认为疱疹病毒在IPF的发生发展过程中起致病作用。病毒对IPF相关的肺高血压的影响尚不清楚。该研究重点探讨病毒对IPF患者肺高血压相关方面的影响,同时还对γ疱疹病毒[鼠疱疹病毒68(maus herpesvirus 68,MHV-68)]诱发的肺间质纤维化实验室小鼠模型进行评估。 | Calabrese F Kipar A Lunardi F Balestro E Perissinotto E Rossi E Nannini N Marulli G Stewart JP Rea F 刘莉 叶鹏 | 2013 | 中华高血压杂志2013，21，5： | 2 |
| 4 | A direct link between the China loess and marine δ^18O records:Aeolian flux to the north Pacific显示文摘 | Hovan S A Rea D K PisiasN G | 1989 | Nature1989，340，： | 1 |
| 5 | Dry deposition and foliar leaching of mercury and selected trace elements in deciduous forest throughfall显示文摘 | Rea A W Lindberg S E Keeler G J | 2001 | Atmospheric Environment2001，35，： | 1 |
| 6 | Pesticide sorption onto aquifer sediments 显示文摘 | Rea J E Cooper C S Parker A | 1998 | J of Geochemical Exploration1998，64，： | 1 |
| 7 | Clinical evoked electromyography for recurrent laryngeal nerve preservation: use of an endotracheal tube electrode and a postcricoid surface electrode 显示文摘 | Rea JL Khan A | 1998 | Laryngoscope1998，108，12： | 1 |
| 8 | Biohydrometallurgical iron oxidation and precipitation: Part I-- Effect of pH on process performance显示文摘 | KAKSONEN A H MORRIS C REA S LI J WYLIE J USHER K M G1NIGE M P CHENG K Y HILARIO F du PLESSIS C A | 2014 | Hydrometallurgy2014，，： | 1 |
| 9 | Lung abnormalities after dasatinib treatment for chronic myeloid leukemia: a case series显示文摘 | Bergeron A Rea D Levy V | 2007 | Am J Respir Crit Care Med2007，176，8： | 1 |
| 10 | Acidic residues necessary for pyrophosphate-energized pumping and inhibition of the vacuolar H+-pyrophosphatase by N,N'-dicyclohexylcarbodiimide显示文摘 | Zhen R G Kim E J Rea P A | 1997 | Journal of Biological Chemistry1997，272，22： | 1 |
| 11 | A new sphineter- splitting operation for surgical access to low-lying tumors of the rectum显示文摘 | Fingerhut A Rea S Pourcher J | 1988 | Ital J Surg Sci1988，18，1： | 1 |
| 12 | Predicting survival after out- of-hospital cardiac arrest : role of the Utstein data elements 显示文摘 | Rea TD Cook A J Stiell IG | 2010 | Ann Emerg Med2010，55，3： | 1 |
| 13 | Acinetobacter baumannii bloodstream infection while receiving tigecycline:a cautionary report显示文摘 | Peleg A Y Potoski B A Rea R | 2007 | J Antimicrob Chemother2007，59，1： | 1 |
| 14 | Vacuolar uptake of the phytoa-lexin medicarpin by the glutathione conjugate pump 显示文摘 | Li Z S Alfenito M Rea P A | 1997 | Phytochemistry1997，45，： | 1 |
| 15 | Response of bushbean exposed to acid rain mist显示文摘 | Hindawi I J Rea J A Griffis W L | 1980 | American Journalof Botany1980，67，2： | 1 |
| 16 | Upgrade and de novo cardiac resynchronization therapy:impact of paced or intrinsic QRS morphology on outcomes and survival显示文摘 | Wokhlu A Rea RF Asirvatham SJ | 2009 | Heart Rhythm2009，6，10： | 1 |
| 17 | Plant ATP-binding cassette transporters显示文摘 | Rea P A | 2007 | Annual Review of Plant Biology2007，58，： | 1 |
| 18 | From vacuolar GS-X pumps to multispecific ABC transparters显示文摘 | Rea P A Li Z S Lu Y P | 1998 | Annual Review of Plant Physiology and Plant Molecular Biology1998，49，： | 1 |
| 19 | Long electron-hole separation of ZnO-CdS core-shell quantum dots 显示文摘 | XU F VOLKOV V ZHU Y BAI H Y REA A VALAPPIL N V SU W GAO X Y KUSKOVSKY I L MATSUI H | 2009 | Journal of Physical Chemistry C2009，113，19： | 1 |
| 20 | Neodymium isotopic variation in North Pacific modern silicate sediment and the insignificance of detrital REE contributions to seawater显示文摘 | Jones C E Halliday A N Rea D K | 1994 | Earth and Planetary Science Letters1994，127，： | 1 |
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