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| 1 | Effect of ginger Effect of ginger on gastric motility and symptoms of functional dyspepsiaon gastric motility and symptoms of functional dyspepsia显示文摘AIM:To evaluate the effects of ginger on gastric motility and emptying,abdominal symptoms,and hormones that influence motility in dyspepsia.METHODS:Eleven patients with functional dyspepsia were studied twice in a randomized double-blind manner.After an 8-h fast,the patients ingested three capsules that contained ginger(total 1.2 g) or placebo,followed after 1 h by 500 mL low-nutrient soup.Antral area,fundus area and diameter,and the frequency of antral contractions were measured using ultrasound at frequent intervals,and the gastric half-emptying time was calculated from the change in antral area.Gastrointestinal sensations and appetite were scored using visual analog questionnaires,and blood was taken for measurement of plasma glucagon-like peptide-1(GLP-1),motilin and ghrelin concentrations,at intervals throughout the study.RESULTS:Gastric emptying was more rapid after ginger than placebo [median(range) half-emptying time 12.3(8.5-17.0) min after ginger,16.1(8.3-22.6) min after placebo,P ≤ 0.05].There was a trend for more antral contractions(P = 0.06),but fundus dimensions and gastrointestinal symptoms did not differ,nor did serum concentrations of GLP-1,motilin and ghrelin.CONCLUSION:Ginger stimulated gastric emptying and antral contractions in patients with functional dyspepsia,but had no impact on gastrointestinal symptoms or gut peptides. | Ming-Luen Hu Christophan K Rayner Keng-Liang Wu Seng-Kee Chuah Wei-Chen Tai Yeh-Pin Chou Yi-Chun Chiu King-Wah Chiu Tsung-Hui Hu | 2011 | World Journal of Gastroenterology2011，17，1： | 19 |
| 2 | Whey protein: The “whey” forward for treatment of type 2 diabetes?显示文摘A cost-effective nutritional approach to improve postprandial glycaemia is attractive considering the rising burden of diabetes throughout the world. Whey protein, a by-product of the cheese-making process, can be used to manipulate gut function in order to slow gastric emptying and stimulate incretin hormone secretion, thereby attenuating postprandial glycaemic excursions. The function of the gastrointestinal tract plays a pivotal role in glucose homeostasis, particularly during the postprandial period, and this review will discuss the mechanisms by which whey protein slows gastric emptying and stimulates release of gut peptides, including the incretins. Whey protein is also a rich source of amino acids, and these can directly stimulate beta cells to secrete insulin, which contributes to the reduction in postprandial glycaemia. Appetite is suppressed with consumption of whey, due to its effects on the gut-brain axis and the hypothalamus. These properties of whey protein suggest its potential in the management of type 2 diabetes. However, the optimal dose and timing of whey protein ingestion are yet to be defined, and studies are required to examine the long-term benefits of whey consumption for overall glycaemic control. | Linda E Mignone Tongzhi Wu Michael Horowitz Christopher K Rayner | 2015 | World Journal of Diabetes2015，6，14： | 2 |
| 3 | Extracellular release of the atheroprotective heat shock protein 27 is mediated by estrogen and competitively inhibits acLDL binding to scavenger receptor-A显示文摘 | Rayner K Chen Y X McNulty M | 2008 | Circ Res2008，103，2： | 1 |
| 4 | Localisation of mRNA for JE/MCP-1 and its receptor CCR2 in atherosclerotic lesions of the ApoE knockout mouse显示文摘 | Rayner K van Eersel S Groot P H | 2000 | J Vasc Res2000，37，2： | 1 |
| 5 | Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of ath-erosclerosis显示文摘 | Rayner K J Sheedy FJ Esau CC | | 0，，： | 1 |
| 6 | Jones and michael horowitz pathophysiology and management of gastroparesis expert review of gastroenterology & hepatology显示文摘 | Joan Khoo Christopher K Rayner Karen L | 2009 | April2009，3，2： | 1 |
| 7 | Linezolid for the treatment of multidrug-resistant, grampositive infections: experience from a compassionate-use program 显示文摘 | Birmingham M C Rayner C R Meagher A K | 2003 | Clin Infect Dis2003，36，： | 1 |
| 8 | Eye movements when looking at print advertisements:the goal of the viewer matters显示文摘 | Rayner K Miller B Rotello C.M | | 0，，05： | 1 |
| 9 | The role of microRNAs in cholesterol efflux and hepatic lipid metabolism显示文摘 | Moore K J Rayner K J Suárez Y | | 0，，： | 1 |
| 10 | Heat shock protein 27:clue to understanding estrogen-mediated atheroprotection显示文摘 | Rayner K Chen YX Siebert T | | 0，，： | 1 |
| 11 | NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals显示文摘 | Duewell P Kono H Rayner K J | 2010 | Nature2010，464，7293： | 1 |
| 12 | Localisation of mRNA for JE/MCP-1 and its receptor CCR2 in athero- sclerotic lesions of the ApoE knockout mouse 显示文摘 | Rayner K Van Eersel S Groot PHE | 2000 | J Vas- cular Res2000，37，2： | 1 |
| 13 | How Psychological Science In forms the Teaching of Reading 显示文摘 | RAYNER K FOORMAN B R PERFETTI C A PESETSKY D SEIDENBERG M S | 2001 | Psychological Science in the Public Interest2001，2，2： | 1 |
| 14 | Making and correcting errors during sentence comprehension: Eye movements in the analysis of structurally ambiguous sentences显示文摘 | FRAZIER L RAYNER K | 1982 | Cognitive Psychology1982，14，2： | 1 |
| 15 | Extracellular release of the atheroprotective heat shock protein 27 is mediated by estrogen and competitively inhibits ac LDL binding to scavenger receptor-A 显示文摘 | Rayner K Chen YX McNulty M | 2008 | Circ Res2008，103，2： | 1 |
| 16 | Recent patterns and mechanisms of carbon exchange by terrestrial ecosystems显示文摘 | Schimel D S House J I Hibbard K A Bousquet P Ciais P Peylin P Braswell B H Apps M J Baker D Bondeau A Canadell J Churkina C: Cramer W Denning A S Field CB Friedlingstein P Goodale C Heimann M Houghton RA Melillo J M Moore B 3rd Murdiyarso D Noble L Pacala S W Prentice I C Raupach M R Rayner P J Scholes R J Steffen W L Wirth C | 2001 | Nature2001，414，： | 1 |
| 17 | Eye movements in reading and information processing:20years of research显示文摘 | Rayner K | 1998 | Psychological bulletin1998，，124： | 1 |
| 18 | Effect of contextual constraint on eyemovements in reading:A further examina-tion 显示文摘 | Rayner K Amold D W | 1996 | Psychonomic Bulletin &Rev/ew1996，，4： | 1 |
| 19 | Heat shock protein 27: clue to understanding estrogen-mediated athero protection? 显示文摘 | Rayner K Chen YX Siebert T | 2010 | Trends Cardiovasc Med2010，20，2： | 1 |
| 20 | Integrating text and pictorial information:eye movements when looking at print advertisements显示文摘 | Rayner K Rotello C.M Stewart A.J | | 0，，： | 1 |
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