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| 1 | 大鼠中风模型的超小氧化铁粒子神经血管成像(英文)显示文摘现今诱导血管增生剂在中风后的治疗效应引起了人们的关注.这项工作的一个目的是用短时脑中动脉栓塞大鼠中风模型(MCAO)和磁化率加权成像(SWI)的核磁共振成像(MRI)方法,监测在中风后半月形损伤区新生成的旁侧血管.P904是法国格尔伯实验室生产的超小超顺磁氧化铁粒子弛豫试剂(USPIO).它在低剂量减少T1弛豫时间,适中剂量时减少T2*弛豫时间.实验动物被随机分为3组:中风Sildenafil治疗组(n=6)、中风无治疗对照组(n=5)和无中风无治疗对照组(n=1).在P904注入前后分别进行MRI成像.磁化率加权成像的时间点是:栓塞手术前、栓塞手术后24小时、栓塞手术后两周和四周.结果表明,术后两周,在治疗组中中风严重的动物的缺血区的周边显示了MRI可见的新生血管.结论:在短时脑中动脉栓塞大鼠中风模型中,使用超小超顺磁氧化铁粒子弛豫试剂和7 T高分辨磁化率加权成像能够监测半月形损伤区新生血管的形成. | 沈伊民 郑伟丽 CHENG Yu-Chung N 丁玉川 HIGASHIDA Tetsuhiro 李杰 叶永泉 RAYNAUD Jean-Sebastien HAACKE E Mark | 2014 | 波谱学杂志2014，31，1： | 2 |
| 2 | Substrate oxidation during exercise: type 2 diabetes is associated with a decrease in lipid oxidation and an earlier shift towards carbohydrate utilization显示文摘 | E Ghanassia JF Brun C Fedou E Raynaud J Mercier | 2006 | Diabetes and Metabolism2006，，6： | 1 |
| 3 | Balance of Substrate Oxidation during Submaximal Exercise in Lean and Obese People显示文摘 | PEREZ-MARTIN A DUMORTIER M RAYNAUD E | 2001 | Diabetes Metab2001，27，41： | 1 |
| 4 | Alignment Between Quality Enforcement Devices and Governance Structures in the Agro-food Vertical Chains显示文摘 | Raynaud E Sauvee L Valceschini E | | 0，，01： | 1 |
| 5 | Effect of a high dose of simvastatin on muscle mitochondrial metab- olism and calcium signaling in healthy volunteers 显示文摘 | Galtier F Mura T Raynaud de Mauverger E | 2012 | Toxi col Appl Pharmacol2012，263，3： | 1 |
| 6 | Rho-GTPase-activating protein interacting with Cdc-42-interacting protein 4 homolog 2 (Rich2): A new Ras-related C3 botulinum toxin substrate 1 (Racl) GTPase-activating protein that controls dendritic spine morphogenesis显示文摘 | Raynaud F Moutin E Schmidt S | 2014 | J Biol Chem2014，289，5： | 1 |
| 7 | Discovery of epigenetically silenced genes in acute myeloid leukemias显示文摘 | Desmond JC Raynaud S Tung E | 2007 | Leukemia2007，21，： | 1 |
| 8 | Calpain 1-titin internactions concentrate calpain 1 in the Z-band edges and in the N2-line region within the skeletal myofibril显示文摘 | Raynaud F Fernandez E Coulis G | 2005 | FEBS Journal2005，272，： | 1 |
| 9 | Climate and atmospheric history of the past 420,000 years from the Vostok ice core, Antarctica 显示文摘 | Petit J R Jouzl J Raynaud D Barkov N I Barnola J M Basile I Bender M Chappellaz J Davis M Delay- gue G Delmotte M Kotlyakov V M Legrand M Lipenkov V Y Lorius C Pepin L Ritz C Saltzman E Stievenard M | 1999 | Nature1999，399，6735： | 1 |
| 10 | Stable carbon cycle climate relationship during the late pleistocene显示文摘 | Siegenthaler U Stocker T F Monnin E L thi D Schwander J Stauffer B Raynaud D Barnola J-M Fischer H Masson-Delmotte V Jouzel J | 2005 | Sci- ence2005，310，5752： | 1 |
| 11 | Fa- milial benign chronic pemphigus and doxycycline: a re- view of 6 cases 显示文摘 | Le Sache-De PL Raynaud E Bouchardeau A | 2014 | J Eur Acad Dermatol Venereol2014，28，3： | 1 |
| 12 | Magnetic resonance imaging of ruptured plaques in the rabbit with ultrasmall superparamagnetic particles of iron oxide显示文摘 | Durand E Raynaud JS Bruneval P | | 0，，： | 1 |
| 13 | Rho-GTPase-activating protein interacting with Cdc-42-interacting protein 4 homolog 2 (Rich2): a new Ras-related C3 botulinum toxin substrate 1 (Racl) GTPase-activating protein that controls dendritic spine morphogenesis显示文摘 | Raynaud F Moutin E Schmidt S | 2014 | J Biol Chem2014，289，5： | 1 |
| 14 | Discovery of epigenetically silenced genes in acute myeloid leukemias显示文摘 | Desmond JC Raynaud S Tung E | 2007 | Leukemia2007，21，5： | 1 |
| 15 | Balance of substrate oxidation during submaximal exercise in lean and obese people 显示文摘 | PEREZ-MARTIN A DUMORTIER M RAYNAUD E | 2001 | Diabetes Metab2001，27，4： | 1 |
| 16 | Corymboside, nouvelle di-C-gl ycosylflavone des Racines de carline corymbosa 显示文摘 | Besson E Dombris A Raynaud J | 1979 | Phytochemistry1979，18，： | 1 |
| 17 | Bal- ance of substrate oxidation during submaximal exercise in lean and obese people显示文摘 | Perez-Martin A Durnortier M Raynaud E | 2001 | Diabetes Metabolism2001，，27： | 1 |
| 18 | cis-Amminedichloro(2-methyl-pyridine) platinum(Ⅱ) (AMD473), a novel sterically hindered platinum complex: in vivo activity, toxicology, and phmmacokinetics in mice显示文摘 | Raynaud F I Boxell F E Goddard P M | 1997 | Clin Cancer Res1997，3，11： | 1 |
| 19 | 查看详情显示文摘 | Raynaud S Champion E Bernache- Assolant D | | 0，，： | 1 |
| 20 | Emulsifying Properties of biodegradable polylactide-grafted dextran copolymers显示文摘 | Raynaud J Choquenet B Marie E Dellacherie E Nouvel C Six J L Durand A | 2008 | Biorrmcromolecules2008，9，： | 1 |
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